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Volumn , Issue , 2009, Pages 27-71

Oxysterols and oxysterol-binding proteins in cellular lipid metabolism

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EID: 84900108597     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-00300-4_2     Document Type: Chapter
Times cited : (3)

References (270)
  • 1
    • 10644239801 scopus 로고    scopus 로고
    • Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs
    • Adams CM, Reitz J, De Brabander JK, Feramisco JD, Li L, Brown MS, Goldstein JL (2004) Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs. J Biol Chem 279 : 52772-52780
    • (2004) J Biol Chem , vol.279 , pp. 52772-52780
    • Adams, C.M.1    Reitz, J.2    De Brabander, J.K.3    Feramisco, J.D.4    Li, L.5    Brown, M.S.6    Goldstein, J.L.7
  • 3
    • 0032554080 scopus 로고    scopus 로고
    • A Drosophila homologue of oxysterol binding protein (OSBP) - implications for the role of OSBP
    • Alphey L, Jimenez J, Glover D (1998) A Drosophila homologue of oxysterol binding protein (OSBP) - implications for the role of OSBP. Biochim Biophys Acta. 1395 : 159-164
    • (1998) Biochim Biophys Acta , vol.1395 , pp. 159-164
    • Alphey, L.1    Jimenez, J.2    Glover, D.3
  • 4
    • 14044268935 scopus 로고    scopus 로고
    • Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction
    • Amarilio R, Ramachandran S, Sabanay H, Lev S (2005) Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction. J Biol Chem 280 : 5934-5944
    • (2005) J Biol Chem , vol.280 , pp. 5934-5944
    • Amarilio, R.1    Ramachandran, S.2    Sabanay, H.3    Lev, S.4
  • 6
    • 23844452073 scopus 로고    scopus 로고
    • Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation
    • Antonny B, Bigay J, Casella JF, Drin G, Mesmin B, Gounon P (2005) Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation. Biochem Soc Trans 33 : 619-622
    • (2005) Biochem Soc Trans , vol.33 , pp. 619-622
    • Antonny, B.1    Bigay, J.2    Casella, J.F.3    Drin, G.4    Mesmin, B.5    Gounon, P.6
  • 7
    • 0028025654 scopus 로고
    • A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily
    • Apfel R, Benbrook D, Lernhardt E, Ortiz MA, Salbert G, Pfahl M (1994) A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily. Mol Cell Biol 14 : 7025-7035
    • (1994) Mol Cell Biol , vol.14 , pp. 7025-7035
    • Apfel, R.1    Benbrook, D.2    Lernhardt, E.3    Ortiz, M.A.4    Salbert, G.5    Pfahl, M.6
  • 8
    • 33846811272 scopus 로고    scopus 로고
    • Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: Reduction During atorvastatin and fenofibrate therapy
    • Arca M, Natoli S, Micheletta F, Riggi S, Di Angelantonio E, Montali A, Antonini TM, Antonini R, Diczfalusy U, Iuliano L (2007) Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: Reduction During atorvastatin and fenofibrate therapy. Free Radic Biol Med 42 : 698-705
    • (2007) Free Radic Biol Med , vol.42 , pp. 698-705
    • Arca, M.1    Natoli, S.2    Micheletta, F.3    Riggi, S.4    Di Angelantonio, E.5    Montali, A.6    Antonini, T.M.7    Antonini, R.8    Diczfalusy, U.9    Iuliano, L.10
  • 10
    • 0030720329 scopus 로고    scopus 로고
    • Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport
    • Babiker A, Andersson O, Lund E, Xiu RJ, Deeb S, Reshef A, Leitersdorf E, Diczfalusy U, Björkhem I (1997) Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport. J Biol Chem 272 : 26253-26261
    • (1997) J Biol Chem , vol.272 , pp. 26253-26261
    • Babiker, A.1    Andersson, O.2    Lund, E.3    Xiu, R.J.4    Deeb, S.5    Reshef, A.6    Leitersdorf, E.7    Diczfalusy, U.8    Björkhem, I.9
  • 11
    • 0036696804 scopus 로고    scopus 로고
    • Escrt-III: An endosomeassociated heterooligomeric protein complex required for mvb sorting
    • Babst M, Katzmann DJ, Estepa-Sabal EJ, Meerloo T, Emr SD (2002a) Escrt-III: An endosomeassociated heterooligomeric protein complex required for mvb sorting. Dev Cell 3 : 271-282
    • (2002) Dev Cell , vol.3 , pp. 271-282
    • Babst, M.1    Katzmann, D.J.2    Estepa-Sabal, E.J.3    Meerloo, T.4    Emr, S.D.5
  • 12
    • 0036697166 scopus 로고    scopus 로고
    • Endosome-Associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body
    • Babst M, Katzmann DJ, Snyder WB, Wendland B, Emr SD (2002b) Endosome-Associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev Cell 3 : 283-289
    • (2002) Dev Cell , vol.3 , pp. 283-289
    • Babst, M.1    Katzmann, D.J.2    Snyder, W.B.3    Wendland, B.4    Emr, S.D.5
  • 13
    • 28444461398 scopus 로고    scopus 로고
    • Phosphatidylinositol transfer protein function in the yeast Saccharomyces cerevisiae
    • Bankaitis VA, Phillips S, Yanagisawa L, Li X, Routt S, Xie Z (2005) Phosphatidylinositol transfer protein function in the yeast Saccharomyces cerevisiae. Adv Enzyme Regul 45 : 155-170
    • (2005) Adv Enzyme Regul , vol.45 , pp. 155-170
    • Bankaitis, V.A.1    Phillips, S.2    Yanagisawa, L.3    Li, X.4    Routt, S.5    Xie, Z.6
  • 15
    • 4344641314 scopus 로고    scopus 로고
    • A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution
    • Beh CT, Rine J (2004) A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution. J Cell Sci 117 : 2983-2996
    • (2004) J Cell Sci , vol.117 , pp. 2983-2996
    • Beh, C.T.1    Rine, J.2
  • 16
    • 0035108917 scopus 로고    scopus 로고
    • Overlapping functions of the yeast oxysterol-binding protein homologues
    • Beh CT, Cool L, Phillips J, Rine J (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157 : 1117-1140
    • (2001) Genetics , vol.157 , pp. 1117-1140
    • Beh, C.T.1    Cool, L.2    Phillips, J.3    Rine, J.4
  • 18
    • 0022600652 scopus 로고
    • Characterization of oxysterol-binding protein in rat embryo fibroblasts and variations as a function of the cell cycle
    • Beseme F, Astruc ME, Defay R, Descomps B, Crastes De Paulet A (1986) Characterization of oxysterol-binding protein in rat embryo fibroblasts and variations as a function of the cell cycle. Biochim Biophys Acta 886 : 96-108
    • (1986) Biochim Biophys Acta , vol.886 , pp. 96-108
    • Beseme, F.1    Astruc, M.E.2    Defay, R.3    Descomps, B.4    Crastes De Paulet, A.5
  • 19
    • 0023088792 scopus 로고
    • Rat liver cytosol oxysterol-binding protein Characterization and comparison with the HTC cell protein
    • Beseme F, Astruc ME, Defay R, Crastes de Paulet A (1987) Rat liver cytosol oxysterol-binding protein. Characterization and comparison with the HTC cell protein. FEBS Lett 210 : 97-103
    • (1987) FEBS Lett , vol.210 , pp. 97-103
    • Beseme, F.1    Astruc, M.E.2    Defay, R.3    Crastes De Paulet, A.4
  • 20
    • 34247139296 scopus 로고    scopus 로고
    • Selective up-regulation of LXR-regulated genes ABCA1, ABCG, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol
    • Beyea MM, Heslop CL, Sawyez CG, Edwards JY, Markle JG, Hegele RA, Huff MW (2007) Selective up-regulation of LXR-regulated genes ABCA1, ABCG, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol. J Biol Chem 282 : 5207-5216
    • (2007) J Biol Chem , vol.282 , pp. 5207-5216
    • Beyea, M.M.1    Heslop, C.L.2    Sawyez, C.G.3    Edwards, J.Y.4    Markle, J.G.5    Hegele, R.A.6    Huff, M.W.7
  • 22
    • 22744442219 scopus 로고    scopus 로고
    • ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif
    • Bigay J, Casella JF, Drin G, Mesmin B, Antonny B (2005) ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif. EMBO J 24 : 2244-2253
    • (2005) EMBO J , vol.24 , pp. 2244-2253
    • Bigay, J.1    Casella, J.F.2    Drin, G.3    Mesmin, B.4    Antonny, B.5
  • 23
    • 0022446878 scopus 로고
    • Assay of unesterified 7-oxocholesterol in human serum by isotope dilution-mass spectrometry
    • Björkhem I (1986) Assay of unesterified 7-oxocholesterol in human serum by isotope dilution-mass spectrometry. Anal Biochem 154 : 497-501
    • (1986) Anal Biochem , vol.154 , pp. 497-501
    • Björkhem, I.1
  • 24
  • 25
    • 0035076216 scopus 로고    scopus 로고
    • Genes involved in initial steps of bile acid synthesis
    • Björkhem I, Eggertsen G (2001) Genes involved in initial steps of bile acid synthesis. Curr Opin Lipidol 12 : 97-103
    • (2001) Curr Opin Lipidol , vol.12 , pp. 97-103
    • Björkhem, I.1    Eggertsen, G.2
  • 26
    • 0028068796 scopus 로고
    • Atherosclerosis and sterol 27-hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages
    • Björkhem I, Andersson O, Diczfalusy U, Sevastik B, Xiu RJ, Duan C, Lund E (1994) Atherosclerosis and sterol 27-hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages. Proc Natl Acad Sci USA 91 : 8592-8596
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8592-8596
    • Björkhem, I.1    Andersson, O.2    Diczfalusy, U.3    Sevastik, B.4    Xiu, R.J.5    Duan, C.6    Lund, E.7
  • 27
    • 0030729021 scopus 로고    scopus 로고
    • Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro
    • Björkhem I, Lütjohann D, Breuer O, Sakinis A, Wennmalm A (1997) Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro. J Biol Chem 272 : 30178-30184
    • (1997) J Biol Chem , vol.272 , pp. 30178-30184
    • Björkhem, I.1    Lütjohann, D.2    Breuer, O.3    Sakinis, A.4    Wennmalm, A.5
  • 29
    • 0026033178 scopus 로고
    • Oxysterols, cholesterol biosyn thesis, and vascular endothelial cell monolayer barrier function
    • Boissonneault GA, Hennig B, Ouyang CM (1991) Oxysterols, cholesterol biosynthesis, and vascular endothelial cell monolayer barrier function. Proc Soc Exp Biol Med 196 : 338-343
    • (1991) Proc Soc Exp Biol Med , vol.196 , pp. 338-343
    • Boissonneault, G.A.1    Hennig, B.2    Ouyang, C.M.3
  • 30
    • 30844437681 scopus 로고    scopus 로고
    • Docosahexaneoic acid (22:6,n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- And 26S proteasome-dependent pathways
    • Botolin D, Wang Y, Christian B, Jump DB (2006) Docosahexaneoic acid (22:6,n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- And 26S proteasome-dependent pathways. J Lipid Res 47 : 181-192
    • (2006) J Lipid Res , vol.47 , pp. 181-192
    • Botolin, D.1    Wang, Y.2    Christian, B.3    Jump, D.B.4
  • 31
    • 49649095715 scopus 로고    scopus 로고
    • Oxysterol binding protein (OSBP) negatively regulates ATP binding cassette transporter A1 (ABCA1) protein stability
    • Bowden K, Ridgway ND (2008) Oxysterol binding protein (OSBP) negatively regulates ATP binding cassette transporter A1 (ABCA1) protein stability. J Biol Chem 283 : 18210-18217
    • (2008) J Biol Chem , vol.283 , pp. 18210-18217
    • Bowden, K.1    Ridgway, N.D.2
  • 33
    • 0016206178 scopus 로고
    • Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol
    • Brown MS, Goldstein JL (1974) Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol. J Biol Chem 249 : 7306-7314
    • (1974) J Biol Chem , vol.249 , pp. 7306-7314
    • Brown, M.S.1    Goldstein, J.L.2
  • 34
    • 0032890337 scopus 로고    scopus 로고
    • Oxysterols and atherosclerosis
    • Brown AJ, Jessup W (1999) Oxysterols and atherosclerosis. Atherosclerosis 142 : 1-28
    • (1999) Atherosclerosis , vol.142 , pp. 1-28
    • Brown, A.J.1    Jessup, W.2
  • 35
    • 0033995604 scopus 로고    scopus 로고
    • Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells Accumulation of oxidized esters in lysosomes
    • Brown AJ, Mander EL, Gelissen IC, Kritharides L, Dean RT, Jessup W (2000a) Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells. Accumulation of oxidized esters in lysosomes. J Lipid Res 41 : 226-237
    • (2000) J Lipid Res , vol.41 , pp. 226-237
    • Brown, A.J.1    Mander, E.L.2    Gelissen, I.C.3    Kritharides, L.4    Dean, R.T.5    Jessup, W.6
  • 36
    • 0034623160 scopus 로고    scopus 로고
    • Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture
    • Brown AJ, Watts GF, Burnett JR, Dean RT, Jessup W (2000b) Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture. J Biol Chem 275 : 27627-27633
    • (2000) J Biol Chem , vol.275 , pp. 27627-27633
    • Brown, A.J.1    Watts, G.F.2    Burnett, J.R.3    Dean, R.T.4    Jessup, W.5
  • 37
    • 0036671360 scopus 로고    scopus 로고
    • Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism
    • Brown AJ, Sun L, Feramisco JD, Brown MS, Goldstein JL (2002) Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism. Mol Cell 10 : 237-245
    • (2002) Mol Cell , vol.10 , pp. 237-245
    • Brown, A.J.1    Sun, L.2    Feramisco, J.D.3    Brown, M.S.4    Goldstein, J.L.5
  • 40
    • 0242361567 scopus 로고    scopus 로고
    • Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism
    • Castrillo A, Joseph SB, Vaidya SA, Haberland M, Fogelman AM, Cheng G, Tontonoz P (2003) Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Mol Cell 12 : 805-816
    • (2003) Mol Cell , vol.12 , pp. 805-816
    • Castrillo, A.1    Joseph, S.B.2    Vaidya, S.A.3    Haberland, M.4    Fogelman, A.M.5    Cheng, G.6    Tontonoz, P.7
  • 41
    • 0030908862 scopus 로고    scopus 로고
    • Characterization of cholesterol oxidation products formed by oxidative modification of low density lipoprotein
    • Chang YH, Abdalla DS, Sevanian A (1997) Characterization of cholesterol oxidation products formed by oxidative modification of low density lipoprotein. Free Radic Biol Med 23 : 202-214
    • (1997) Free Radic Biol Med , vol.23 , pp. 202-214
    • Chang, Y.H.1    Abdalla, D.S.2    Sevanian, A.3
  • 42
    • 0036237015 scopus 로고    scopus 로고
    • 25-hydroxycholesterol is produced by testicular macrophages during the early postnatal period and influences differentiation of Leydig cells in vitro
    • Chen JJ, Lukyanenko Y, Hutson JC (2002) 25-hydroxycholesterol is produced by testicular macrophages during the early postnatal period and influences differentiation of Leydig cells in vitro. Biol Reprod 66 : 1336-1341
    • (2002) Biol Reprod , vol.66 , pp. 1336-1341
    • Chen, J.J.1    Lukyanenko, Y.2    Hutson, J.C.3
  • 43
    • 33845587711 scopus 로고    scopus 로고
    • Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
    • Chen W, Chen G, Head DL, Mangelsdorf DJ, Russell DW (2007) Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. Cell Metab 5 : 73-79
    • (2007) Cell Metab , vol.5 , pp. 73-79
    • Chen, W.1    Chen, G.2    Head, D.L.3    Mangelsdorf, D.J.4    Russell, D.W.5
  • 44
    • 0028134883 scopus 로고
    • 7 beta-hydroperoxycholest-5-en-3 beta-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein
    • Chisolm GM, Ma G, Irwin KC, Martin LL, Gunderson KG, Linberg LF, Morel DW, DiCorleto PE (1994) 7 beta-hydroperoxycholest-5-en-3 beta-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein. Proc Natl Acad Sci USA 91 : 11452-11456
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11452-11456
    • Chisolm, G.M.1    Ma, G.2    Irwin, K.C.3    Martin, L.L.4    Gunderson, K.G.5    Linberg, L.F.6    Morel, D.W.7    DiCorleto, P.E.8
  • 45
    • 0035185753 scopus 로고    scopus 로고
    • Oxidized LDL-induced injury and apoptosis in atherosclerosis Potential roles for oxysterols
    • Colles SM, Maxson JM, Carlson SG, Chisolm GM (2001) Oxidized LDL-induced injury and apoptosis in atherosclerosis. Potential roles for oxysterols. Trends Cardiovasc Med 11 : 131-138
    • (2001) Trends Cardiovasc Med , vol.11 , pp. 131-138
    • Colles, S.M.1    Maxson, J.M.2    Carlson, S.G.3    Chisolm, G.M.4
  • 47
    • 33744788672 scopus 로고    scopus 로고
    • Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells
    • Corcoran RB, Scott MP (2006) Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells. Proc Natl Acad Sci USA 103 : 8408-8413
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 8408-8413
    • Corcoran, R.B.1    Scott, M.P.2
  • 48
    • 0034623288 scopus 로고    scopus 로고
    • Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
    • Costet P, Luo Y, Wang N, Tall AR (2000) Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J Biol Chem 275 : 28240-28245
    • (2000) J Biol Chem , vol.275 , pp. 28240-28245
    • Costet, P.1    Luo, Y.2    Wang, N.3    Tall, A.R.4
  • 49
    • 47649123929 scopus 로고    scopus 로고
    • The multiple roles of PtdIns(4) P - not just the precursor of PtdIns(4,5)P 2
    • D'Angelo G, Vicinauza M, Di Campli A, De Matteis MA (2008) The multiple roles of PtdIns(4) P - not just the precursor of PtdIns(4,5)P 2. J Cell Sci 121 : 1955-1963
    • (2008) J Cell Sci , vol.121 , pp. 1955-1963
    • D'Angelo, G.1    Vicinauza, M.2    Di Campli, A.3    De Matteis, M.A.4
  • 51
    • 0024422669 scopus 로고
    • Cdna cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper
    • Dawson PA, Ridgway ND, Slaughter CA, Brown MS, Goldstein JL (1989a) cDNA cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper. J Biol Chem 264 : 16798-16803
    • (1989) J Biol Chem , vol.264 , pp. 16798-16803
    • Dawson, P.A.1    Ridgway, N.D.2    Slaughter, C.A.3    Brown, M.S.4    Goldstein, J.L.5
  • 55
    • 33644638521 scopus 로고    scopus 로고
    • Estrogen receptors and human Disease
    • Deroo BJ, Korach KS (2006) Estrogen receptors and human Disease. J Clin Invest 116 : 561-570
    • (2006) J Clin Invest , vol.116 , pp. 561-570
    • Deroo, B.J.1    Korach, K.S.2
  • 57
    • 34247844371 scopus 로고    scopus 로고
    • Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells
    • Dwyer JR, Sever N, Carlson M, Nelson SF, Beachy PA, Parhami F (2007) Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells. J Biol Chem 282 : 8959-8968
    • (2007) J Biol Chem , vol.282 , pp. 8959-8968
    • Dwyer, J.R.1    Sever, N.2    Carlson, M.3    Nelson, S.F.4    Beachy, P.A.5    Parhami, F.6
  • 58
    • 0028816863 scopus 로고
    • Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry
    • Dzeletovic S, Breuer O, Lund E, Diczfalusy U (1995) Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry. Anal Biochem 225 : 73-80
    • (1995) Anal Biochem , vol.225 , pp. 73-80
    • Dzeletovic, S.1    Breuer, O.2    Lund, E.3    Diczfalusy, U.4
  • 59
    • 10044271037 scopus 로고    scopus 로고
    • SREBP transcription factors: Master regulators of lipid homeostasis
    • Eberle D, Hegarty B, Bossard P, Ferre P, Foufelle F (2004) SREBP transcription factors: Master regulators of lipid homeostasis. Biochimie 86 : 839-848
    • (2004) Biochimie , vol.86 , pp. 839-848
    • Eberle, D.1    Hegarty, B.2    Bossard, P.3    Ferre, P.4    Foufelle, F.5
  • 61
    • 34047127402 scopus 로고    scopus 로고
    • Expression of ATP-binding cassette-Transporter ABCG1 prevents cell death by transporting cytotoxic 7 b -hydroxycholesterol
    • Engel T, Kannenberg F, Fobker M, Nofer J-R, Bode G, Lueken A, Assmann G, Seedorf U (2007) Expression of ATP-binding cassette-Transporter ABCG1 prevents cell death by transporting cytotoxic 7 b -hydroxycholesterol. FEBS Lett 581 : 1673-1680
    • (2007) FEBS Lett , vol.581 , pp. 1673-1680
    • Engel, T.1    Kannenberg, F.2    Fobker, M.3    Nofer, J.-R.4    Bode, G.5    Lueken, A.6    Assmann, G.7    Seedorf, U.8
  • 62
    • 33947106449 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages
    • Erridge C, Webb DJ, Spickett CM (2007) 25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages. Free Radic Res 41 : 260-266
    • (2007) Free Radic Res , vol.41 , pp. 260-266
    • Erridge, C.1    Webb, D.J.2    Spickett, C.M.3
  • 63
    • 18844430347 scopus 로고    scopus 로고
    • Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein-related protein 1 short) in the regulation of vesicular transport
    • Fairn GD, McMaster CR (2005a) Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein- related protein 1 short) in the regulation of vesicular transport. Biochem J 387 : 889-896
    • (2005) Biochem J , vol.387 , pp. 889-896
    • Fairn, G.D.1    McMaster, C.R.2
  • 64
    • 29144498313 scopus 로고    scopus 로고
    • The roles of the human lipid-binding proteins ORP9S and ORP10S in vesicular transport
    • Fairn GD, McMaster CR (2005b) The roles of the human lipid-binding proteins ORP9S and ORP10S in vesicular transport. Biochem Cell Biol 83 : 631-636
    • (2005) Biochem Cell Biol , vol.83 , pp. 631-636
    • Fairn, G.D.1    McMaster, C.R.2
  • 65
    • 34848818827 scopus 로고    scopus 로고
    • The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function
    • Fairn GD, Curwin AJ, Stefan CJ, McMaster CR (2007) The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function. Proc Natl Acad Sci USA 104 : 15352-15357
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15352-15357
    • Fairn, G.D.1    Curwin, A.J.2    Stefan, C.J.3    McMaster, C.R.4
  • 66
    • 0029803610 scopus 로고    scopus 로고
    • Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis
    • Fang M, Kearns BG, Gedvilaite A, Kagiwada S, Kearns M, Fung MK, Bankaitis VA (1996) Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis. EMBO J 15 : 6447-6459
    • (1996) EMBO J , vol.15 , pp. 6447-6459
    • Fang, M.1    Kearns, B.G.2    Gedvilaite, A.3    Kagiwada, S.4    Kearns, M.5    Fung, M.K.6    Bankaitis, V.A.7
  • 67
    • 0030885520 scopus 로고    scopus 로고
    • The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism
    • Forman BM, Ruan B, Chen J, Schroepfer GJ Jr, Evans RM (1997) The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism. Proc Natl Acad Sci USA 94 : 10588-10593
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10588-10593
    • Forman, B.M.1    Ruan, B.2    Chen, J.3    Schroepfer Jr., G.J.4    Evans, R.M.5
  • 69
    • 0037063345 scopus 로고    scopus 로고
    • OSBPa, a predicted oxysterol binding protein of Dictyostelium, is required for regulated entry into culmination
    • Fukuzawa M, Williams JG (2002) OSBPa, a predicted oxysterol binding protein of Dictyostelium, is required for regulated entry into culmination. FEBS Lett 527 : 37-42
    • (2002) FEBS Lett , vol.527 , pp. 37-42
    • Fukuzawa, M.1    Williams, J.G.2
  • 72
    • 0030008367 scopus 로고    scopus 로고
    • Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol
    • Gelissen IC, Brown AJ, Mander EL, Kritharides L, Dean RT, Jessup W (1996) Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol. J Biol Chem 271 : 17852-17860
    • (1996) J Biol Chem , vol.271 , pp. 17852-17860
    • Gelissen, I.C.1    Brown, A.J.2    Mander, E.L.3    Kritharides, L.4    Dean, R.T.5    Jessup, W.6
  • 73
    • 53149118574 scopus 로고    scopus 로고
    • Sterol regulators of cholesterol homeostasis and beyond: The oxysterol hypothesis revisited and revised
    • Gill S, Chow R, Brown AJ (2008) Sterol regulators of cholesterol homeostasis and beyond: The oxysterol hypothesis revisited and revised. Progr Lipid Res 47 : 391-404
    • (2008) Progr Lipid Res , vol.47 , pp. 391-404
    • Gill, S.1    Chow, R.2    Brown, A.J.3
  • 78
    • 0025315653 scopus 로고
    • Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region
    • Guyton JR, Black BL, Seidel CL (1990) Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region. Am J Pathol 137 : 425-434
    • (1990) Am J Pathol , vol.137 , pp. 425-434
    • Guyton, J.R.1    Black, B.L.2    Seidel, C.L.3
  • 80
    • 1542328927 scopus 로고    scopus 로고
    • Structure, regulation and function of PKB/AKT-A major therapeutic target
    • Hanada M, Feng J, Hemmings BA (2004) Structure, regulation and function of PKB/AKT-A major therapeutic target. Biochim Biophys Acta 1697 : 3-16
    • (2004) Biochim Biophys Acta , vol.1697 , pp. 3-16
    • Hanada, M.1    Feng, J.2    Hemmings, B.A.3
  • 82
    • 15944391363 scopus 로고    scopus 로고
    • Sterol homeostasis in the budding yeast, Saccharomyces cerevisiae
    • Henneberry AL, Sturley SL (2005) Sterol homeostasis in the budding yeast, Saccharomyces cerevisiae. Semin Cell Dev Biol 16 : 155-161
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 155-161
    • Henneberry, A.L.1    Sturley, S.L.2
  • 84
    • 57649233033 scopus 로고    scopus 로고
    • Direct interaction of nuclear receptor LXR b with ABCA1 modulates cholesterol efflux
    • Hojozi M, Munehira Y, Ikeda Y, Makishima M, Matsuo M, Kioka N, Ueda K (2008) Direct interaction of nuclear receptor LXR b with ABCA1 modulates cholesterol efflux. J Biol Chem 283 : 30057-30063
    • (2008) J Biol Chem , vol.283 , pp. 30057-30063
    • Hojozi, M.1    Munehira, Y.2    Ikeda, Y.3    Makishima, M.4    Matsuo, M.5    Kioka, N.6    Ueda, K.7
  • 85
    • 0027139362 scopus 로고
    • SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element
    • Hua X, Yokoyama C, Wu J, Briggs MR, Brown MS, Goldstein JL, Wang X (1993) SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. Proc Natl Acad Sci USA 90 : 11603-11607
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11603-11607
    • Hua, X.1    Yokoyama, C.2    Wu, J.3    Briggs, M.R.4    Brown, M.S.5    Goldstein, J.L.6    Wang, X.7
  • 86
    • 2442614716 scopus 로고    scopus 로고
    • Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism
    • Hult M, Elleby B, Shafqat N, Svensson S, Rane A, Jornvall H, Abrahmsen L, Oppermann U (2004) Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism. Cell Mol Life Sci 61 : 992-999
    • (2004) Cell Mol Life Sci , vol.61 , pp. 992-999
    • Hult, M.1    Elleby, B.2    Shafqat, N.3    Svensson, S.4    Rane, A.5    Jornvall, H.6    Abrahmsen, L.7    Oppermann, U.8
  • 87
    • 33947109086 scopus 로고    scopus 로고
    • Characterization of Osh3, an oxysterol-binding protein, in filamentous growth of Saccharomyces cerevisiae and Candida albicans
    • Hur HS, Ryu JH, Kim KH, Kim J (2006) Characterization of Osh3, an oxysterol-binding protein, in filamentous growth of Saccharomyces cerevisiae and Candida albicans. J Microbiol 44 : 523-529
    • (2006) J Microbiol , vol.44 , pp. 523-529
    • Hur, H.S.1    Ryu, J.H.2    Kim, K.H.3    Kim, J.4
  • 89
    • 38549141572 scopus 로고    scopus 로고
    • Cellular cholesterol trafficking and compartmentalization
    • Ikonen E (2008) Cellular cholesterol trafficking and compartmentalization. Nat Rev Mol Cell Biol 9 : 125-138
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 125-138
    • Ikonen, E.1
  • 90
    • 24344455560 scopus 로고    scopus 로고
    • Structural mechanism for sterol sensing and transport by OSBP-related proteins
    • Im YJ, Raychaudhuri S, Prinz WA, Hurley JH (2005) Structural mechanism for sterol sensing and transport by OSBP-related proteins. Nature 437 : 154-158
    • (2005) Nature , vol.437 , pp. 154-158
    • Im, Y.J.1    Raychaudhuri, S.2    Prinz, W.A.3    Hurley, J.H.4
  • 91
    • 38149069055 scopus 로고    scopus 로고
    • Purified NPC1 protein I Binding of cholesterol and oxysterols to a 1278-Amino acid membrane protein
    • Infante RE, Abi-Mosleh L, Radhakrishnan A, Dale JD, Brown MS, Goldstein JL (2008a) Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-Amino acid membrane protein . J Biol Chem 283 : 1052-1063
    • (2008) J Biol Chem , vol.283 , pp. 1052-1063
    • Infante, R.E.1    Abi-Mosleh, L.2    Radhakrishnan, A.3    Dale, J.D.4    Brown, M.S.5    Goldstein, J.L.6
  • 93
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
    • Janowski BA, Willy PJ, Devi TR, Falck JR, Mangelsdorf DJ (1996) An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 383 : 728-731
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 95
    • 0035976936 scopus 로고    scopus 로고
    • The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols
    • Janowski BA, Shan B, Russell DW (2001) The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols. J Biol Chem 276 : 45408-45416
    • (2001) J Biol Chem , vol.276 , pp. 45408-45416
    • Janowski, B.A.1    Shan, B.2    Russell, D.W.3
  • 96
    • 4544363033 scopus 로고    scopus 로고
    • Oxysteroids: A new class of steroids with autocrine and paracrine functions
    • Javitt NB (2004) Oxysteroids: A new class of steroids with autocrine and paracrine functions. Trends Endocrinol Metab 15 : 393-397
    • (2004) Trends Endocrinol Metab , vol.15 , pp. 393-397
    • Javitt, N.B.1
  • 97
    • 37649021073 scopus 로고    scopus 로고
    • Oxysterols: Novel biologic roles for the 21st century
    • Javitt NB (2008) Oxysterols: Novel biologic roles for the 21st century. Steroids 73 : 149-157
    • (2008) Steroids , vol.73 , pp. 149-157
    • Javitt, N.B.1
  • 98
    • 0035885867 scopus 로고    scopus 로고
    • A family of 12 human genes containing oxysterol-binding domains
    • Jaworski CJ, Moreira E, Li A, Lee R, Rodriguez IR (2001) A family of 12 human genes containing oxysterol-binding domains. Genomics 78 : 185-196
    • (2001) Genomics , vol.78 , pp. 185-196
    • Jaworski, C.J.1    Moreira, E.2    Li, A.3    Lee, R.4    Rodriguez, I.R.5
  • 99
    • 0028213802 scopus 로고
    • A new family of yeast genes implicated in ergosterol synthesis is related to the human oxysterol binding protein
    • Jiang B, Brown JL, Sheraton J, Fortin N, Bussey H (1994) A new family of yeast genes implicated in ergosterol synthesis is related to the human oxysterol binding protein. Yeast 10 : 341-353
    • (1994) Yeast , vol.10 , pp. 341-353
    • Jiang, B.1    Brown, J.L.2    Sheraton, J.3    Fortin, N.4    Bussey, H.5
  • 100
    • 0037342401 scopus 로고    scopus 로고
    • The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinct
    • Johansson M, Bocher V, Lehto M, Chinetti G, Kuismanen E, Ehnholm C, Staels B, Olkkonen VM (2003) The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinct. Mol Biol Cell 14 : 903-915
    • (2003) Mol Biol Cell , vol.14 , pp. 903-915
    • Johansson, M.1    Bocher, V.2    Lehto, M.3    Chinetti, G.4    Kuismanen, E.5    Ehnholm, C.6    Staels, B.7    Olkkonen, V.M.8
  • 101
    • 28644446115 scopus 로고    scopus 로고
    • The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments
    • Johansson M, Lehto M, Tanhuanpää K, Cover TL, Olkkonen VM (2005) The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments. Mol Biol Cell 16 : 5480-5492
    • (2005) Mol Biol Cell , vol.16 , pp. 5480-5492
    • Johansson, M.1    Lehto, M.2    Tanhuanpää, K.3    Cover, T.L.4    Olkkonen, V.M.5
  • 102
    • 33847003020 scopus 로고    scopus 로고
    • Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin
    • Johansson M, Rocha N, Zwart W, Jordens I, Janssen L, Kuijl C, Olkkonen VM, Neefjes J (2007) Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin. J Cell Biol 176 : 459-471
    • (2007) J Cell Biol , vol.176 , pp. 459-471
    • Johansson, M.1    Rocha, N.2    Zwart, W.3    Jordens, I.4    Janssen, L.5    Kuijl, C.6    Olkkonen, V.M.7    Neefjes, J.8
  • 107
    • 23944462533 scopus 로고    scopus 로고
    • Overexpression of OSBP-related protein 2 (ORP2) in CHO cells induces alterations of phospholipid species composition
    • Käkelä R, Tanhuanpää K, Laitinen S, Somerharju P, Olkkonen VM (2005) Overexpression of OSBP-related protein 2 (ORP2) in CHO cells induces alterations of phospholipid species composition. Biochem Cell Biol 83 : 677-683
    • (2005) Biochem Cell Biol , vol.83 , pp. 677-683
    • Käkelä, R.1    Tanhuanpää, K.2    Laitinen, S.3    Somerharju, P.4    Olkkonen, V.M.5
  • 108
    • 0016256292 scopus 로고
    • Inhibition of sterol synthesis in cultured mouse cells by cholesterol derivatives oxygenated in the side chain
    • Kandutsch AA, Chen HW (1974) Inhibition of sterol synthesis in cultured mouse cells by cholesterol derivatives oxygenated in the side chain. J Biol Chem 249 : 6057-6061
    • (1974) J Biol Chem , vol.249 , pp. 6057-6061
    • Kandutsch, A.A.1    Chen, H.W.2
  • 109
    • 0019809230 scopus 로고
    • Assay of oxysterol-binding protein in a mouse fibroblast, cell-free system. Dissociation constant and other properties of the system
    • Kandutsch AA, Shown EP (1981) Assay of oxysterol-binding protein in a mouse fibroblast, cell-free system. Dissociation constant and other properties of the system. J Biol Chem 256 : 13068-13073
    • (1981) J Biol Chem , vol.256 , pp. 13068-13073
    • Kandutsch, A.A.1    Shown, E.P.2
  • 110
    • 0019168614 scopus 로고
    • Cytosolic proteins that bind oxygenated sterols. Cellular distribution, specificity, and some properties
    • Kandutsch AA, Thompson EB (1980) Cytosolic proteins that bind oxygenated sterols. Cellular distribution, specificity, and some properties. J Biol Chem 255 : 10813-10821
    • (1980) J Biol Chem , vol.255 , pp. 10813-10821
    • Kandutsch, A.A.1    Thompson, E.B.2
  • 111
    • 0017702258 scopus 로고
    • Binding of 25-hydroxycholesterol and cholesterol to different cytoplasmic proteins
    • Kandutsch AA, Chen HW, Shown EP (1977) Binding of 25-hydroxycholesterol and cholesterol to different cytoplasmic proteins. Proc Natl Acad Sci USA 74 : 2500-2503
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 2500-2503
    • Kandutsch, A.A.1    Chen, H.W.2    Shown, E.P.3
  • 112
    • 0018079091 scopus 로고
    • Biological activity of some oxygenated sterols
    • Kandutsch AA, Chen HW, Heiniger HJ (1978) Biological activity of some oxygenated sterols. Science 201 : 498-501
    • (1978) Science , vol.201 , pp. 498-501
    • Kandutsch, A.A.1    Chen, H.W.2    Heiniger, H.J.3
  • 113
    • 0347034082 scopus 로고    scopus 로고
    • Characterization of the human ABCG1 gene: Liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein
    • Kennedy MA, Venkateswaran A, Tarr PT, Xenarios I, Kudoh J, Shimizu N, Edwards PA (2001) Characterization of the human ABCG1 gene: Liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. J Biol Chem 276 : 39438-39447
    • (2001) J Biol Chem , vol.276 , pp. 39438-39447
    • Kennedy, M.A.1    Venkateswaran, A.2    Tarr, P.T.3    Xenarios, I.4    Kudoh, J.5    Shimizu, N.6    Edwards, P.A.7
  • 115
    • 38449113816 scopus 로고    scopus 로고
    • 20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism
    • Kim WK, Meliton V, Amantea CM, Hahn TJ, Parhami F (2007) 20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism. J Bone Miner Res 22 : 1711-1719
    • (2007) J Bone Miner Res , vol.22 , pp. 1711-1719
    • Kim, W.K.1    Meliton, V.2    Amantea, C.M.3    Hahn, T.J.4    Parhami, F.5
  • 119
    • 33746939368 scopus 로고    scopus 로고
    • Homologues of oxysterol-binding proteins affect Cdc42p- And Rho1p-mediated cell polarization in Saccharomyces cerevisiae
    • Kozminski KG, Alfaro G, Dighe S, Beh CT (2006) Homologues of oxysterol-binding proteins affect Cdc42p- And Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7 : 1-19
    • (2006) Traffic , vol.7 , pp. 1-19
    • Kozminski, K.G.1    Alfaro, G.2    Dighe, S.3    Beh, C.T.4
  • 120
  • 121
    • 8744254603 scopus 로고    scopus 로고
    • Nvj1p is the outer-nuclear-membrane receptor for oxysterol-binding protein homolog Osh1p in Saccharomyces cerevisiae
    • Kvam E, Goldfarb DS (2004) Nvj1p is the outer-nuclear-membrane receptor for oxysterol-binding protein homolog Osh1p in Saccharomyces cerevisiae. J Cell Sci 117 : 4959-4968
    • (2004) J Cell Sci , vol.117 , pp. 4959-4968
    • Kvam, E.1    Goldfarb, D.S.2
  • 122
    • 0030882949 scopus 로고    scopus 로고
    • Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain
    • Lagace TA, Byers DM, Cook HW, Ridgway ND (1997) Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain. Biochem J 326 : 205-213
    • (1997) Biochem J , vol.326 , pp. 205-213
    • Lagace, T.A.1    Byers, D.M.2    Cook, H.W.3    Ridgway, N.D.4
  • 123
    • 0032895139 scopus 로고    scopus 로고
    • Chinese hamster ovary cells overexpressing the oxysterol binding protein (OSBP) display enhanced synthesis of sphingomyelin in response to 25-hydroxycholesterol
    • Lagace TA, Byers DM, Cook HW, Ridgway ND (1999) Chinese hamster ovary cells overexpressing the oxysterol binding protein (OSBP) display enhanced synthesis of sphingomyelin in response to 25-hydroxycholesterol. J Lipid Res 40 : 109-116
    • (1999) J Lipid Res , vol.40 , pp. 109-116
    • Lagace, T.A.1    Byers, D.M.2    Cook, H.W.3    Ridgway, N.D.4
  • 125
    • 0028999147 scopus 로고
    • Movement of 25-hydroxycholesterol from the plasma membrane to the rough endoplasmic reticulum in cultured hepatoma cells
    • Lange Y, Ye J, Strebel F (1995) Movement of 25-hydroxycholesterol from the plasma membrane to the rough endoplasmic reticulum in cultured hepatoma cells. J Lipid Res 36 : 1092-1097
    • (1995) J Lipid Res , vol.36 , pp. 1092-1097
    • Lange, Y.1    Ye, J.2    Strebel, F.3
  • 126
    • 38349112601 scopus 로고    scopus 로고
    • Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase
    • Lange Y, Ory DS, Ye J, Lanier MH, Hsu FF, Steck TL (2008) Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase. J Biol Chem 283 : 1445-1455
    • (2008) J Biol Chem , vol.283 , pp. 1445-1455
    • Lange, Y.1    Ory, D.S.2    Ye, J.3    Lanier, M.H.4    Hsu, F.F.5    Steck, T.L.6
  • 127
    • 33747329092 scopus 로고    scopus 로고
    • Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects
    • Larsson DA, Baird S, Nyhalah JD, Yuan XM, Li W (2006) Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects. Free Radic Biol Med 41 : 902-910
    • (2006) Free Radic Biol Med , vol.41 , pp. 902-910
    • Larsson, D.A.1    Baird, S.2    Nyhalah, J.D.3    Yuan, X.M.4    Li, W.5
  • 129
    • 0037455984 scopus 로고    scopus 로고
    • The OSBP-related proteins: A novel protein family involved in vesicle transport, cellular lipid metabolism, and cell signalling
    • Lehto M, Olkkonen VM (2003) The OSBP-related proteins: A novel protein family involved in vesicle transport, cellular lipid metabolism, and cell signalling. Biochim Biophys Acta 1631 : 1-11
    • (2003) Biochim Biophys Acta , vol.1631 , pp. 1-11
    • Lehto, M.1    Olkkonen, V.M.2
  • 131
    • 2342447668 scopus 로고    scopus 로고
    • Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: The expression and intracellular localization of ORP3, ORP6, and ORP7
    • Lehto M, Tienari J, Lehtonen S, Lehtonen E, Olkkonen VM (2004) Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: The expression and intracellular localization of ORP3, ORP6, and ORP7. Cell Tissue Res 315 : 39-57
    • (2004) Cell Tissue Res , vol.315 , pp. 39-57
    • Lehto, M.1    Tienari, J.2    Lehtonen, S.3    Lehtonen, E.4    Olkkonen, V.M.5
  • 132
    • 26844518949 scopus 로고    scopus 로고
    • Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants
    • Lehto M, Hynynen R, Karjalainen K, Kuismanen E, Hyvarinen K, Olkkonen VM (2005) Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants. Exp Cell Res 310 : 445-462
    • (2005) Exp Cell Res , vol.310 , pp. 445-462
    • Lehto, M.1    Hynynen, R.2    Karjalainen, K.3    Kuismanen, E.4    Hyvarinen, K.5    Olkkonen, V.M.6
  • 135
    • 67349196703 scopus 로고    scopus 로고
    • 7 B -Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: Oxysterols-induced IL-8 secretion is calcium-dependent
    • in press), DOI: PMID 18317936
    • Lemaire-Ewing S, Berthier A, Royer MC, Logette E, Corcos L, Bouchot A, Monier S, Prunet C, Raveneau M, Rebe C, Desrumaux C, Lizard G, Neel D (2008) 7 b -Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: Oxysterols-induced IL-8 secretion is calcium-dependent. Cell Biol Toxicol (in press), DOI: PMID 18317936
    • (2008) Cell Biol Toxicol
    • Lemaire-Ewing, S.1    Berthier, A.2    Royer, M.C.3    Logette, E.4    Corcos, L.5    Bouchot, A.6    Monier, S.7    Prunet, C.8    Raveneau, M.9    Rebe, C.10    Desrumaux, C.11    Lizard, G.12    Neel, D.13
  • 136
    • 1642422735 scopus 로고    scopus 로고
    • Trojan horse-like behavior of a biologically representative mixture of oxysterols
    • Leonarduzzi G, Biasi F, Chiarpotto E, Poli G (2004) Trojan horse-like behavior of a biologically representative mixture of oxysterols. Mol Aspects Med 25 : 155-167
    • (2004) Mol Aspects Med , vol.25 , pp. 155-167
    • Leonarduzzi, G.1    Biasi, F.2    Chiarpotto, E.3    Poli, G.4
  • 138
    • 0037131563 scopus 로고    scopus 로고
    • Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis
    • Leoni V, Masterman T, Diczfalusy U, De Luca G, Hillert J, Björkhem I (2002) Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis. Neurosci Lett 331 : 163-166
    • (2002) Neurosci Lett , vol.331 , pp. 163-166
    • Leoni, V.1    Masterman, T.2    Diczfalusy, U.3    De Luca, G.4    Hillert, J.5    Björkhem, I.6
  • 139
    • 33845698910 scopus 로고    scopus 로고
    • Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation
    • Lessmann E, Ngo M, Leitges M, Minguet S, Ridgway ND, Huber M (2007) Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation. Cell Signal 19 : 384-392
    • (2007) Cell Signal , vol.19 , pp. 384-392
    • Lessmann, E.1    Ngo, M.2    Leitges, M.3    Minguet, S.4    Ridgway, N.D.5    Huber, M.6
  • 140
    • 2942518361 scopus 로고    scopus 로고
    • The role of the Nir/rdgB protein family in membrane trafficking and cytoskeleton remodeling
    • Lev S (2004) The role of the Nir/rdgB protein family in membrane trafficking and cytoskeleton remodeling. Exp Cell Res 297 : 1-10
    • (2004) Exp Cell Res , vol.297 , pp. 1-10
    • Lev, S.1
  • 141
    • 0025144236 scopus 로고
    • Cdna cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19
    • Levanon D, Hsieh CL, Francke U, Dawson PA, Ridgway ND, Brown MS, Goldstein JL (1990) cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19. Genomics 7 : 65-74
    • (1990) Genomics , vol.7 , pp. 65-74
    • Levanon, D.1    Hsieh, C.L.2    Francke, U.3    Dawson, P.A.4    Ridgway, N.D.5    Brown, M.S.6    Goldstein, J.L.7
  • 142
    • 4444307875 scopus 로고    scopus 로고
    • Short-range intracellular trafficking of small molecules across endoplasmic reticulum junctions
    • Levine T (2004) Short-range intracellular trafficking of small molecules across endoplasmic reticulum junctions. Trends Cell Biol 14 : 483-490
    • (2004) Trends Cell Biol , vol.14 , pp. 483-490
    • Levine, T.1
  • 143
    • 0032543562 scopus 로고    scopus 로고
    • The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes
    • Levine TP, Munro S (1998) The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes. Curr Biol 8 : 729-739
    • (1998) Curr Biol , vol.8 , pp. 729-739
    • Levine, T.P.1    Munro, S.2
  • 144
    • 0035163224 scopus 로고    scopus 로고
    • Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction
    • Levine TP, Munro S (2001) Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction. Mol Biol Cell 12 : 1633-1644
    • (2001) Mol Biol Cell , vol.12 , pp. 1633-1644
    • Levine, T.P.1    Munro, S.2
  • 145
    • 0037197804 scopus 로고    scopus 로고
    • Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components
    • Levine TP, Munro S (2002) Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components. Curr Biol 12 : 695-704
    • (2002) Curr Biol , vol.12 , pp. 695-704
    • Levine, T.P.1    Munro, S.2
  • 146
    • 10044223533 scopus 로고    scopus 로고
    • PPAR- And LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis
    • Li AC, Glass CK (2004) PPAR- And LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J Lipid Res 45 : 2161-2173
    • (2004) J Lipid Res , vol.45 , pp. 2161-2173
    • Li, A.C.1    Glass, C.K.2
  • 147
    • 37049000132 scopus 로고    scopus 로고
    • Molecular characterization of a novel salt-inducible gene for an OSBP (oxysterol-binding protein)-homologue from soybean
    • Li DY, Inoue H, Takahashi M, Kojima T, Shiraiwa M, Takahara H (2008) Molecular characterization of a novel salt-inducible gene for an OSBP (oxysterol-binding protein)-homologue from soybean . Gene 407 : 12-20
    • (2008) Gene , vol.407 , pp. 12-20
    • Li, D.Y.1    Inoue, H.2    Takahashi, M.3    Kojima, T.4    Shiraiwa, M.5    Takahara, H.6
  • 149
    • 0036544518 scopus 로고    scopus 로고
    • Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex
    • Li X, Rivas MP, Fang M, Marchena J, Mehrotra B, Chaudhary A, Feng L, Prestwich GD, Bankaitis VA (2002) Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex. J Cell Biol 157 : 63-77
    • (2002) J Cell Biol , vol.157 , pp. 63-77
    • Li, X.1    Rivas, M.P.2    Fang, M.3    Marchena, J.4    Mehrotra, B.5    Chaudhary, A.6    Feng, L.7    Prestwich, G.D.8    Bankaitis, V.A.9
  • 150
    • 37249016419 scopus 로고    scopus 로고
    • Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes
    • Li X, Pandak WM, Erickson SK, Ma Y, Yin L, Hylemon P, Ren S (2007) Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes. J Lipid Res 48 : 2587-2596
    • (2007) J Lipid Res , vol.48 , pp. 2587-2596
    • Li, X.1    Pandak, W.M.2    Erickson, S.K.3    Ma, Y.4    Yin, L.5    Hylemon, P.6    Ren, S.7
  • 151
    • 7244238074 scopus 로고    scopus 로고
    • ATP-binding cassette (ABC) transporters mediate nonvesicular, raft-modulated sterol movement from the plasma membrane to the endoplasmic reticulum
    • Li Y, Prinz WA (2004) ATP-binding cassette (ABC) transporters mediate nonvesicular, raft-modulated sterol movement from the plasma membrane to the endoplasmic reticulum. J Biol Chem 279 : 45226-45234
    • (2004) J Biol Chem , vol.279 , pp. 45226-45234
    • Li, Y.1    Prinz, W.A.2
  • 152
    • 0034595445 scopus 로고    scopus 로고
    • Disruption of the oxysterol 7alphahydroxylase gene in mice
    • Li-Hawkins J, Lund EG, Turley SD, Russell DW (2000) Disruption of the oxysterol 7alphahydroxylase gene in mice. J Biol Chem 275 : 16536-16542
    • (2000) J Biol Chem , vol.275 , pp. 16536-16542
    • Li-Hawkins, J.1    Lund, E.G.2    Turley, S.D.3    Russell, D.W.4
  • 153
    • 0038558194 scopus 로고    scopus 로고
    • A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP
    • Loewen CJ, Roy A, Levine TP (2003) A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP. EMBO J 22 : 2025-2035
    • (2003) EMBO J , vol.22 , pp. 2025-2035
    • Loewen, C.J.1    Roy, A.2    Levine, T.P.3
  • 155
    • 36749038234 scopus 로고    scopus 로고
    • Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6betaepoxide
    • Lordan S, O'Callaghan YC, O'Brien NM (2007) Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta- hydroxycholesterol and cholesterol-5beta,6betaepoxide. J Biochem Mol Toxicol 21 : 362-372
    • (2007) J Biochem Mol Toxicol , vol.21 , pp. 362-372
    • Lordan, S.1    O'Callaghan, Y.C.2    O'Brien, N.M.3
  • 156
    • 0027457242 scopus 로고
    • 24-, 25- And 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver
    • Lund E, Björkhem I, Furster C, Wikvall K (1993) 24-, 25- And 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver. Biochim Biophys Acta 1166 : 177-182
    • (1993) Biochim Biophys Acta , vol.1166 , pp. 177-182
    • Lund, E.1    Björkhem, I.2    Furster, C.3    Wikvall, K.4
  • 157
    • 0032545281 scopus 로고    scopus 로고
    • CDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism
    • Lund EG, Kerr TA, Sakai J, Li WP, Russell DW (1998) cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism. J Biol Chem 273 : 34316-34327
    • (1998) J Biol Chem , vol.273 , pp. 34316-34327
    • Lund, E.G.1    Kerr, T.A.2    Sakai, J.3    Li, W.P.4    Russell, D.W.5
  • 158
    • 34547887264 scopus 로고    scopus 로고
    • Cytochrome P450 - physiological key factor against cholesterol accumulation and the atherosclerotic vascular process
    • Luoma PV (2007) Cytochrome P450 - physiological key factor against
    • (2007) Ann Med , vol.39 , pp. 359-370
    • Luoma, P.V.1
  • 160
    • 0029835410 scopus 로고    scopus 로고
    • Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation
    • Lütjohann D, Breuer O, Ahlborg G, Nennesmo I, Siden A, Diczfalusy U, Björkhem I (1996) Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation. Proc Natl Acad Sci USA 93 : 9799-804
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9799-804
    • Lütjohann, D.1    Breuer, O.2    Ahlborg, G.3    Nennesmo, I.4    Siden, A.5    Diczfalusy, U.6    Björkhem, I.7
  • 162
    • 0035952338 scopus 로고    scopus 로고
    • 7-Ketocholesterol delivered to mice in chylomicron remnant-like particles is rapidly metabolised, excreted and does not accumulate in aorta
    • Lyons MA, Brown AJ (2001a) 7-Ketocholesterol delivered to mice in chylomicron remnant-like particles is rapidly metabolised, excreted and does not accumulate in aorta. Biochim Biophys Acta 1530 : 209-218
    • (2001) Biochim Biophys Acta , vol.1530 , pp. 209-218
    • Lyons, M.A.1    Brown, A.J.2
  • 163
    • 0034892932 scopus 로고    scopus 로고
    • Metabolism of an oxysterol, 7-ketocholesterol, by sterol 27-hydroxylase in HepG2 cells
    • Lyons MA, Brown AJ (2001b) Metabolism of an oxysterol, 7-ketocholesterol, by sterol 27-hydroxylase in HepG2 cells. Lipids 36 : 701-711
    • (2001) Lipids , vol.36 , pp. 701-711
    • Lyons, M.A.1    Brown, A.J.2
  • 164
    • 0032832986 scopus 로고    scopus 로고
    • Rapid hepatic metabolism of 7-ketocholesterol in vivo: Implications for dietary oxysterols
    • Lyons MA, Samman S, Gatto L, Brown AJ (1999) Rapid hepatic metabolism of 7-ketocholesterol in vivo: Implications for dietary oxysterols. J Lipid Res 40 : 1846-1857
    • (1999) J Lipid Res , vol.40 , pp. 1846-1857
    • Lyons, M.A.1    Samman, S.2    Gatto, L.3    Brown, A.J.4
  • 165
    • 0034708367 scopus 로고    scopus 로고
    • Oxidized monocyte-derived macrophages in aortic atherosclerotic lesion from apolipoprotein E-deficient mice and from human carotid artery contain lipid peroxides and oxysterols
    • Maor I, Kaplan M, Hayek T, Vaya J, Hoffman A, Aviram M (2000) Oxidized monocyte-derived macrophages in aortic atherosclerotic lesion from apolipoprotein E-deficient mice and from human carotid artery contain lipid peroxides and oxysterols. Biochem Biophys Res Commun 269 : 775-780
    • (2000) Biochem Biophys Res Commun , vol.269 , pp. 775-780
    • Maor, I.1    Kaplan, M.2    Hayek, T.3    Vaya, J.4    Hoffman, A.5    Aviram, M.6
  • 167
    • 0030064188 scopus 로고    scopus 로고
    • Effects of a novel 2,3-oxidosqualene cyclase inhibitor on the regulation of cholesterol biosynthesis in HepG2 cells
    • Mark M, Muller P, Maier R, Eisele B (1996) Effects of a novel 2,3-oxidosqualene cyclase inhibitor on the regulation of cholesterol biosynthesis in HepG2 cells. J Lipid Res 37 : 148-158
    • (1996) J Lipid Res , vol.37 , pp. 148-158
    • Mark, M.1    Muller, P.2    Maier, R.3    Eisele, B.4
  • 168
    • 0030060474 scopus 로고    scopus 로고
    • Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages
    • Mattsson-Hulten L, Lindmark H, Diczfalusy U, Björkhem I, Ottosson M, Liu Y, Bondjers G, Wiklund O (1996) Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages. J Clin Invest 97 : 461-468
    • (1996) J Clin Invest , vol.97 , pp. 461-468
    • Mattsson-Hulten, L.1    Lindmark, H.2    Diczfalusy, U.3    Björkhem, I.4    Ottosson, M.5    Liu, Y.6    Bondjers, G.7    Wiklund, O.8
  • 169
    • 2942739012 scopus 로고    scopus 로고
    • Lysophosphatidylcholine and 7-oxocholesterol modulate Ca2+ signals and inhibit the phosphorylation of endothelial NO synthase and cytosolic phospholipase A2
    • Millanvoye-Van Brussel E, Topal G, Brunet A, Do Pham T, Deckert V, Rendu F, David-Dufilho M (2004) Lysophosphatidylcholine and 7-oxocholesterol modulate Ca2+ signals and inhibit the phosphorylation of endothelial NO synthase and cytosolic phospholipase A2. Biochem J 380 : 533-539
    • (2004) Biochem J , vol.380 , pp. 533-539
    • Millanvoye-Van Brussel, E.1    Topal, G.2    Brunet, A.3    Do Pham, T.4    Deckert, V.5    Rendu, F.6    David-Dufilho, M.7
  • 170
    • 0034947717 scopus 로고    scopus 로고
    • Golgi localization and phosphorylation of oxysterol binding protein in niemann-pick c and u18666a-Treated cells
    • Mohammadi A, Perry RJ, Storey MK, Cook HW, Byers DM, Ridgway ND (2001) Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-Treated cells. J Lipid Res 42 : 1062-1071
    • (2001) J Lipid Res , vol.42 , pp. 1062-1071
    • Mohammadi, A.1    Perry, R.J.2    Storey, M.K.3    Cook, H.W.4    Byers, D.M.5    Ridgway, N.D.6
  • 172
    • 0035947666 scopus 로고    scopus 로고
    • Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina
    • Moreira EF, Jaworski C, Li A, Rodriguez IR (2001) Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina. J Biol Chem 276 : 18570-18578
    • (2001) J Biol Chem , vol.276 , pp. 18570-18578
    • Moreira, E.F.1    Jaworski, C.2    Li, A.3    Rodriguez, I.R.4
  • 173
    • 0029792867 scopus 로고    scopus 로고
    • Comparison of the intracellular metabolism and trafficking of 25-hydroxycholesterol and cholesterol in macrophages
    • Morel DW, Edgerton ME, Warner GE, Johnson WJ, Phillips MC, Rothblat GH (1996) Comparison of the intracellular metabolism and trafficking of 25-hydroxycholesterol and cholesterol in macrophages. J Lipid Res 37 : 2041-2051
    • (1996) J Lipid Res , vol.37 , pp. 2041-2051
    • Morel, D.W.1    Edgerton, M.E.2    Warner, G.E.3    Johnson, W.J.4    Phillips, M.C.5    Rothblat, G.H.6
  • 174
    • 0019420840 scopus 로고
    • Biosynthesis of 24,25-epoxycholesterol from squalene 2, 3; 22,23-dioxide
    • Nelson JA, Steckbeck SR, Spencer TA (1981) Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide. J Biol Chem 256 : 1067-1068
    • (1981) J Biol Chem , vol.256 , pp. 1067-1068
    • Nelson, J.A.1    Steckbeck, S.R.2    Spencer, T.A.3
  • 176
    • 0034602245 scopus 로고    scopus 로고
    • Oxysterol 7 alpha-hydroxylase activity by cholesterol 7 alpha-hydroxylase (CYP7A
    • Norlin M, Andersson U, Björkhem I, Wikvall K (2000a) Oxysterol 7 alpha-hydroxylase activity by cholesterol 7 alpha-hydroxylase (CYP7A). J Biol Chem 275 : 34046-34053
    • (2000) J Biol Chem , vol.275 , pp. 34046-34053
    • Norlin, M.1    Andersson, U.2    Björkhem, I.3    Wikvall, K.4
  • 177
    • 0033779953 scopus 로고    scopus 로고
    • 24-hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A
    • Norlin M, Toll A, Björkhem I, Wikvall K (2000b) 24- hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A). J Lipid Res 41 : 1629-1639
    • (2000) J Lipid Res , vol.41 , pp. 1629-1639
    • Norlin, M.1    Toll, A.2    Björkhem, I.3    Wikvall, K.4
  • 178
    • 39049179735 scopus 로고    scopus 로고
    • Lipids deposited in human atheromatous lesions induce apoptosis of human vascular smooth muscle cells
    • Ohtsuka M, Miyashita Y, Shirai K (2006) Lipids deposited in human atheromatous lesions induce apoptosis of human vascular smooth muscle cells. J Atheroscler Thromb 13 : 256-262
    • (2006) J Atheroscler Thromb , vol.13 , pp. 256-262
    • Ohtsuka, M.1    Miyashita, Y.2    Shirai, K.3
  • 179
    • 11144233997 scopus 로고    scopus 로고
    • Oxysterols and oxysterol binding proteins: Role in lipid metabolism and atherosclerosis
    • Olkkonen VM, Lehto M (2004) Oxysterols and oxysterol binding proteins: Role in lipid metabolism and atherosclerosis. Ann Med 36 : 562-572
    • (2004) Ann Med , vol.36 , pp. 562-572
    • Olkkonen, V.M.1    Lehto, M.2
  • 180
    • 2342637722 scopus 로고    scopus 로고
    • Oxysterol binding proteins: In more than one place at one time
    • Olkkonen VM, Levine TP (2004) Oxysterol binding proteins: In more than one place at one time. Biochem Cell Biol 82 : 87-98
    • (2004) Biochem Cell Biol , vol.82 , pp. 87-98
    • Olkkonen, V.M.1    Levine, T.P.2
  • 181
    • 44849097130 scopus 로고    scopus 로고
    • Epoxycholesterol impairs cholesterol ester hydrolysis in macrophage foam cells, resulting in Decreased cholesterol efflux
    • Ouimet M, Wang M-D, Cadotte N, Ho K, Marcel YL (2008) Epoxycholesterol impairs cholesterol ester hydrolysis in macrophage foam cells, resulting in Decreased cholesterol efflux. Arterioscler Thromb Vasc Biol 28 : 1144-1150
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1144-1150
    • Ouimet, M.1    Wang, M.-D.2    Cadotte, N.3    Ho, K.4    Marcel, Y.L.5
  • 182
    • 33750927892 scopus 로고    scopus 로고
    • ATP-Binding cassette cholesterol transporters and cardiovascular disease
    • Oram JF, Vaughan AM (2006) ATP-Binding cassette cholesterol transporters and cardiovascular disease. Circ Res 99 : 1031-1043
    • (2006) Circ Res , vol.99 , pp. 1031-1043
    • Oram, J.F.1    Vaughan, A.M.2
  • 183
    • 34248210553 scopus 로고    scopus 로고
    • On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis
    • Panzenboeck U, Andersson U, Hansson M, Sattler W, Meaney S, Björkhem I (2007) On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis. J Lipid Res 48 : 1167-1174
    • (2007) J Lipid Res , vol.48 , pp. 1167-1174
    • Panzenboeck, U.1    Andersson, U.2    Hansson, M.3    Sattler, W.4    Meaney, S.5    Björkhem, I.6
  • 184
    • 0036292705 scopus 로고    scopus 로고
    • Two-hybrid cloning and characterization of OSH3, a yeast oxysterol-binding protein homolog
    • Park YU, Hwang O, Kim J (2002) Two-hybrid cloning and characterization of OSH3, a yeast oxysterol-binding protein homolog. Biochem Biophys Res Commun 293 : 733-740
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 733-740
    • Park, Y.U.1    Hwang, O.2    Kim, J.3
  • 185
    • 55549111249 scopus 로고    scopus 로고
    • Coordinated lipid transfer between the ebnoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport
    • Peretti D, Dahan N, Shimoni E, Hirschberg K, Lev S (2008) Coordinated lipid transfer between the ebnoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport. Mol Biol Cell 19 : 3871-3884
    • (2008) Mol Biol Cell , vol.19 , pp. 3871-3884
    • Peretti, D.1    Dahan, N.2    Shimoni, E.3    Hirschberg, K.4    Lev, S.5
  • 186
    • 33744728346 scopus 로고    scopus 로고
    • Oxysterol-binding protein and vesicle-Associated membrane protein-Associated protein are required for sterol-dependent activation of the ceramide transport protein
    • Perry RJ, Ridgway ND (2006) Oxysterol-binding protein and vesicle-Associated membrane protein-Associated protein are required for sterol-dependent activation of the ceramide transport protein. Mol Biol Cell 17 : 2604-2616
    • (2006) Mol Biol Cell , vol.17 , pp. 2604-2616
    • Perry, R.J.1    Ridgway, N.D.2
  • 187
    • 34249848111 scopus 로고    scopus 로고
    • Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig
    • Radhakrishnan A, Ikeda Y, Kwon HJ, Brown MS, Goldstein JL (2007) Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig. Proc Natl Acad Sci USA 104 : 6511-6518
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 6511-6518
    • Radhakrishnan, A.1    Ikeda, Y.2    Kwon, H.J.3    Brown, M.S.4    Goldstein, J.L.5
  • 188
    • 33846975468 scopus 로고    scopus 로고
    • Identification of OORP-T, a novel oocyte-specific gene encoding a protein with a conserved oxysterol binding protein Domain in rainbow trout
    • Ramachandra RK, Lankford SE, Weber GM, Rexroad CE, 3rd, Yao J (2007) Identification of OORP-T, a novel oocyte-specific gene encoding a protein with a conserved oxysterol binding protein Domain in rainbow trout. Mol Reprod Dev 74 : 502-511
    • (2007) Mol Reprod Dev , vol.74 , pp. 502-511
    • Ramachandra, R.K.1    Lankford, S.E.2    Weber, G.M.3    Rexroad III, C.E.4    Yao, J.5
  • 189
    • 33645727511 scopus 로고    scopus 로고
    • Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides
    • Raychaudhuri S, Im YJ, Hurley JH, Prinz WA (2006) Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides. J Cell Biol 173 : 107-119
    • (2006) J Cell Biol , vol.173 , pp. 107-119
    • Raychaudhuri, S.1    Im, Y.J.2    Hurley, J.H.3    Prinz, W.A.4
  • 190
    • 0034518420 scopus 로고    scopus 로고
    • The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
    • Repa JJ, Mangelsdorf DJ (2000) The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Annu Rev Cell Dev Biol 16 : 459-481
    • (2000) Annu Rev Cell Dev Biol , vol.16 , pp. 459-481
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 193
    • 33947573706 scopus 로고    scopus 로고
    • Oxysterol-induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC- And PKA-dependent pathway
    • Richardson JA, Amantea CM, Kianmahd B, Tetradis S, Lieberman JR, Hahn TJ, Parhami F (2007) Oxysterol-induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC- And PKA-dependent pathway. J Cell Biochem 100 : 1131-1145
    • (2007) J Cell Biochem , vol.100 , pp. 1131-1145
    • Richardson, J.A.1    Amantea, C.M.2    Kianmahd, B.3    Tetradis, S.4    Lieberman, J.R.5    Hahn, T.J.6    Parhami, F.7
  • 194
    • 0026564767 scopus 로고
    • Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding
    • Ridgway ND, Dawson PA, Ho YK, Brown MS, Goldstein JL (1992) Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding. J Cell Biol 116 : 307-319
    • (1992) J Cell Biol , vol.116 , pp. 307-319
    • Ridgway, N.D.1    Dawson, P.A.2    Ho, Y.K.3    Brown, M.S.4    Goldstein, J.L.5
  • 195
    • 0032553324 scopus 로고    scopus 로고
    • Differential effects of sphingomyelin hydrolysis and cholesterol transport on oxysterol-binding protein phosphorylation and Golgi localization
    • Ridgway ND, Lagace TA, Cook HW, Byers DM (1998) Differential effects of sphingomyelin hydrolysis and cholesterol transport on oxysterol-binding protein phosphorylation and Golgi localization. J Biol Chem 273 : 31621-31628
    • (1998) J Biol Chem , vol.273 , pp. 31621-31628
    • Ridgway, N.D.1    Lagace, T.A.2    Cook, H.W.3    Byers, D.M.4
  • 197
    • 44349141839 scopus 로고    scopus 로고
    • Oxysterol and diabetes activate STAT3, and control endothelial expression of profilin-1 via OSBP1
    • Romeo GR, Kazlauskas A (2008) Oxysterol and diabetes activate STAT3, and control endothelial expression of profilin-1 via OSBP1. J Biol Chem 283 : 9595-9605
    • (2008) J Biol Chem , vol.283 , pp. 9595-9605
    • Romeo, G.R.1    Kazlauskas, A.2
  • 199
    • 0142120095 scopus 로고    scopus 로고
    • Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: A novel mechanism for the attenuation of foam cell formation
    • Rowe AH, Argmann CA, Edwards JY, Sawyez CG, Morand OH, Hegele RA, Huff MW (2003) Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: A novel mechanism for the attenuation of foam cell formation. Circ Res 93 : 717-725
    • (2003) Circ Res , vol.93 , pp. 717-725
    • Rowe, A.H.1    Argmann, C.A.2    Edwards, J.Y.3    Sawyez, C.G.4    Morand, O.H.5    Hegele, R.A.6    Huff, M.W.7
  • 200
    • 7244248722 scopus 로고    scopus 로고
    • Multiple pools of phosphatidylinositol 4-phosphate detected using the pleckstrin homology domain of Osh2p
    • Roy A, Levine TP (2004) Multiple pools of phosphatidylinositol 4-phosphate detected using the pleckstrin homology domain of Osh2p. J Biol Chem 279 : 44683-44689
    • (2004) J Biol Chem , vol.279 , pp. 44683-44689
    • Roy, A.1    Levine, T.P.2
  • 201
    • 0034672672 scopus 로고    scopus 로고
    • Oxysterol biosynthetic enzymes
    • Russell DW (2000) Oxysterol biosynthetic enzymes. Biochim Biophys Acta 1529 : 126-135
    • (2000) Biochim Biophys Acta , vol.1529 , pp. 126-135
    • Russell, D.W.1
  • 202
    • 25444529284 scopus 로고    scopus 로고
    • The human ABCG1 gene: Identification of LXR response elements that modulate expression in macrophages and liver
    • Sabol SL, Brewer HB, Jr., Santamarina-Fojo S (2005) The human ABCG1 gene: Identification of LXR response elements that modulate expression in macrophages and liver. J Lipid Res 46 : 2151-2167
    • (2005) J Lipid Res , vol.46 , pp. 2151-2167
    • Sabol, S.L.1    Brewer Jr., H.B.2    Santamarina-Fojo, S.3
  • 203
    • 48849096990 scopus 로고    scopus 로고
    • 7-ketocholesterol, a major oxysterol, promotes Pi-induced vascular calcification in cultured smooth muscle cells
    • Saito E, Wachi H, Saro F, Seyama Y (2008) 7-ketocholesterol, a major oxysterol, promotes Pi-induced vascular calcification in cultured smooth muscle cells. J Atheroscler Thromb 15 : 130-137
    • (2008) J Atheroscler Thromb , vol.15 , pp. 130-137
    • Saito, E.1    Wachi, H.2    Saro, F.3    Seyama, Y.4
  • 205
    • 0028048619 scopus 로고
    • SWH1 from yeast encodes a candidate nuclear factor containing ankyrin repeats and showing homology to mammalian oxysterol-binding protein
    • Schmalix WA, Bandlow W (1994) SWH1 from yeast encodes a candidate nuclear factor containing ankyrin repeats and showing homology to mammalian oxysterol-binding protein. Biochim Biophys Acta 1219 : 205-210
    • (1994) Biochim Biophys Acta , vol.1219 , pp. 205-210
    • Schmalix, W.A.1    Bandlow, W.2
  • 206
    • 0342316532 scopus 로고    scopus 로고
    • Oxysterols: Modulators of cholesterol metabolism and other processes
    • Schroepfer GJ Jr (2000) Oxysterols: Modulators of cholesterol metabolism and other processes. Physiol Rev 80 : 361-554
    • (2000) Physiol Rev , vol.80 , pp. 361-554
    • Schroepfer Jr., G.J.1
  • 207
    • 34249863339 scopus 로고    scopus 로고
    • Sterol transport in yeast and the oxysterol binding protein homologue (OSH) family
    • Schulz TA, Prinz WA (2007) Sterol transport in yeast and the oxysterol binding protein homologue (OSH) family. Biochim Biophys Acta 1771 : 769-780
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 769-780
    • Schulz, T.A.1    Prinz, W.A.2
  • 208
    • 2442513350 scopus 로고    scopus 로고
    • Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: Species-specific differences between the rat, human, and hamster enzyme
    • Schweizer RA, Zurcher M, Balazs Z, Dick B, Odermatt A (2004) Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: Species-specific differences between the rat, human, and hamster enzyme. J Biol Chem 279 : 18415-18424
    • (2004) J Biol Chem , vol.279 , pp. 18415-18424
    • Schweizer, R.A.1    Zurcher, M.2    Balazs, Z.3    Dick, B.4    Odermatt, A.5
  • 209
    • 0029164664 scopus 로고
    • Characterization of endothelial cell injury by cholesterol oxidation products found in oxidized LDL
    • Sevanian A, Hodis HN, Hwang J, McLeod LL, Peterson H (1995) Characterization of endothelial cell injury by cholesterol oxidation products found in oxidized LDL. J Lipid Res 36 : 1971-1986
    • (1995) J Lipid Res , vol.36 , pp. 1971-1986
    • Sevanian, A.1    Hodis, H.N.2    Hwang, J.3    McLeod, L.L.4    Peterson, H.5
  • 212
    • 33746786407 scopus 로고    scopus 로고
    • Identification and characterization of PiORP1, a Petunia oxysterol-binding-protein related protein involved in receptor-kinase mediated signaling in pollen, and analysis of the ORP gene family in Arabidopsis
    • Skirpan AL, Dowd PE, Sijacic P, Jaworski CJ, Gilroy S, Kao TH (2006) Identification and characterization of PiORP1, a Petunia oxysterol-binding- protein related protein involved in receptor-kinase mediated signaling in pollen, and analysis of the ORP gene family in Arabidopsis. Plant Mol Biol 61 : 553-565
    • (2006) Plant Mol Biol , vol.61 , pp. 553-565
    • Skirpan, A.L.1    Dowd, P.E.2    Sijacic, P.3    Jaworski, C.J.4    Gilroy, S.5    Kao, T.H.6
  • 214
    • 0024603895 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • 15- 9
    • Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 3 20: 9 15- 9 24
    • (1989) N Engl J Med 3 , vol.20 , Issue.9 , pp. 24
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 215
    • 0032533161 scopus 로고    scopus 로고
    • Cholesterol regulates oxysterol binding protein (OSBP) phosphorylation and Golgi localization in Chinese hamster ovary cells: Correlation with stimulation of sphingomyelin synthesis by 25-hydroxycholesterol
    • Storey MK, Byers DM, Cook HW, Ridgway ND (1998) Cholesterol regulates oxysterol binding protein (OSBP) phosphorylation and Golgi localization in Chinese hamster ovary cells: Correlation with stimulation of sphingomyelin synthesis by 25-hydroxycholesterol. Biochem J 336 : 247-256
    • (1998) Biochem J , vol.336 , pp. 247-256
    • Storey, M.K.1    Byers, D.M.2    Cook, H.W.3    Ridgway, N.D.4
  • 218
    • 0029848607 scopus 로고    scopus 로고
    • Identification of intermediates in the conversion of cholesterol to pregnenolone with a reconstituted cytochrome p-450scc system: Accumulation of the intermediate modulated by the adrenodoxin level
    • Sugano S, Miura R, Morishima N (1996) Identification of intermediates in the conversion of cholesterol to pregnenolone with a reconstituted cytochrome p-450scc system: Accumulation of the intermediate modulated by the adrenodoxin level. J Biochem 120 : 780-787
    • (1996) J Biochem , vol.120 , pp. 780-787
    • Sugano, S.1    Miura, R.2    Morishima, N.3
  • 219
    • 0034885330 scopus 로고    scopus 로고
    • BIP, a BRAM-interacting protein involved in TGF-beta signalling, regulates body length in Caenorhabditis elegans
    • Sugawara K, Morita K, Ueno N, Shibuya H (2001) BIP, a BRAM-interacting protein involved in TGF-beta signalling, regulates body length in Caenorhabditis elegans. Genes Cells 6 : 599-606
    • (2001) Genes Cells , vol.6 , pp. 599-606
    • Sugawara, K.1    Morita, K.2    Ueno, N.3    Shibuya, H.4
  • 221
    • 34249861927 scopus 로고    scopus 로고
    • Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins
    • Sun LP, Seemann J, Goldstein JL, Brown MS (2007) Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins. Proc Natl Acad Sci USA 104 : 6519-6526
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 6519-6526
    • Sun, L.P.1    Seemann, J.2    Goldstein, J.L.3    Brown, M.S.4
  • 222
    • 57449118767 scopus 로고    scopus 로고
    • 7-ketocholesterol upregulates interleukin-6 via mechanisms that are distinct from those of tumor necrosis factor-Alpha, in vascular smooth muscle cells
    • Sung SC, Kim K, Lee KA, Choi KH, Kim SM, Son YH, Moon YS, Eo SK, Rhim BY (2008) 7-ketocholesterol upregulates interleukin-6 via mechanisms that are distinct from those of tumor necrosis factor-Alpha, in vascular smooth muscle cells. J Vasc Res 46 : 36-44
    • (2008) J Vasc Res , vol.46 , pp. 36-44
    • Sung, S.C.1    Kim, K.2    Lee, K.A.3    Choi, K.H.4    Kim, S.M.5    Son, Y.H.6    Moon, Y.S.7    Eo, S.K.8    Rhim, B.Y.9
  • 223
    • 33748420211 scopus 로고    scopus 로고
    • ABCA1 mediates high-Affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells
    • Tam SP, Mok L, Chimini G, Vasa M, Deeley RG (2006) ABCA1 mediates high-Affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells. Am J Physiol Cell Physiol 291 : C490-C502
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Tam, S.P.1    Mok, L.2    Chimini, G.3    Vasa, M.4    Deeley, R.G.5
  • 225
    • 0021747172 scopus 로고
    • Correlation between oxysterol binding to a cytosolic binding protein and potency in the repression of hydroxymethylglutaryl coenzyme A reductase
    • Taylor FR, Saucier SE, Shown EP, Parish EJ, Kandutsch AA (1984) Correlation between oxysterol binding to a cytosolic binding protein and potency in the repression of hydroxymethylglutaryl coenzyme A reductase. J Biol Chem 259 : 12382-12387
    • (1984) J Biol Chem , vol.259 , pp. 12382-12387
    • Taylor, F.R.1    Saucier, S.E.2    Shown, E.P.3    Parish, E.J.4    Kandutsch, A.A.5
  • 226
    • 0024446518 scopus 로고
    • Purification, subunit structure, and DNA binding properties of the mouse oxysterol receptor
    • Taylor FR, Shown EP, Thompson EB, Kandutsch AA (1989) Purification, subunit structure, and DNA binding properties of the mouse oxysterol receptor. J Biol Chem 264 : 18433-18439
    • (1989) J Biol Chem , vol.264 , pp. 18433-18439
    • Taylor, F.R.1    Shown, E.P.2    Thompson, E.B.3    Kandutsch, A.A.4
  • 227
    • 35448980715 scopus 로고    scopus 로고
    • High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1
    • Terasaka N, Wang N, Yvan-Charvet L, Tall AR (2007) High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1. Proc Natl Acad Sci USA 104 : 15093-15098
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15093-15098
    • Terasaka, N.1    Wang, N.2    Yvan-Charvet, L.3    Tall, A.R.4
  • 230
    • 0023044208 scopus 로고
    • Membrane properties of oxysterols Interfacial orientation, influence on membrane permeability and redistribution between membranes
    • Theunissen JJ, Jackson RL, Kempen HJ, Demel RA (1986) Membrane properties of oxysterols. Interfacial orientation, influence on membrane permeability and redistribution between membranes. Biochim Biophys Acta 860 : 66-74
    • (1986) Biochim Biophys Acta , vol.860 , pp. 66-74
    • Theunissen, J.J.1    Jackson, R.L.2    Kempen, H.J.3    Demel, R.A.4
  • 231
    • 0037503924 scopus 로고    scopus 로고
    • Liver X receptor signaling pathways in cardiovascular disease
    • Tontonoz P, Mangelsdorf DJ (2003) Liver X receptor signaling pathways in cardiovascular disease. Mol Endocrinol 17 : 985-993
    • (2003) Mol Endocrinol , vol.17 , pp. 985-993
    • Tontonoz, P.1    Mangelsdorf, D.J.2
  • 233
    • 0023727786 scopus 로고
    • Quantification of oxysterols in Dutch foods: Egg products and mixed diets
    • van De Bovenkamp P, Kosmeijer-Schuil TG, Katan MB (1988) Quantification of oxysterols in Dutch foods: Egg products and mixed diets. Lipids 23 : 1079-1085
    • (1988) Lipids , vol.23 , pp. 1079-1085
    • Van De Bovenkamp, P.1    Kosmeijer-Schuil, T.G.2    Katan, M.B.3
  • 235
    • 0036472330 scopus 로고    scopus 로고
    • Oxysterol-binding-protein (OSBP -related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments
    • Wang C, JeBailey L, Ridgway ND (2002) Oxysterol-binding-protein (OSBP)-related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments. Biochem J 361 : 461-472
    • (2002) Biochem J , vol.361 , pp. 461-472
    • Wang, C.1    JeBailey, L.2    Ridgway, N.D.3
  • 236
    • 25444460845 scopus 로고    scopus 로고
    • Molecular characterization of Osh6p, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae
    • Wang P, Duan W, Munn AL, Yang H (2005a) Molecular characterization of Osh6p, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae. FEBS J 272 : 4703-4715
    • (2005) FEBS J , vol.272 , pp. 4703-4715
    • Wang, P.1    Duan, W.2    Munn, A.L.3    Yang, H.4
  • 237
    • 25444529050 scopus 로고    scopus 로고
    • AAA ATPases regulate membrane association of yeast oxysterol binding proteins and sterol metabolism
    • Wang P, Zhang Y, Li H, Chieu HK, Munn AL, Yang H (2005b) AAA ATPases regulate membrane association of yeast oxysterol binding proteins and sterol metabolism. EMBO J 24 : 2989-2999
    • (2005) EMBO J , vol.24 , pp. 2989-2999
    • Wang, P.1    Zhang, Y.2    Li, H.3    Chieu, H.K.4    Munn, A.L.5    Yang, H.6
  • 238
    • 14644391519 scopus 로고    scopus 로고
    • OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation
    • Wang PY, Weng J, Anderson RG (2005c) OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation. Science 307 : 1472-1476
    • (2005) Science , vol.307 , pp. 1472-1476
    • Wang, P.Y.1    Weng, J.2    Anderson, R.G.3
  • 239
    • 43149086626 scopus 로고    scopus 로고
    • N-Terminus controls sterol binding while c-Terminus regulates scaffolding function of OSBP
    • Wang PY, Weng J, Lee S, Anderson RG (2008a) N-Terminus controls sterol binding while c-Terminus regulates scaffolding function of OSBP. J Biol Chem 283 : 8034-8045
    • (2008) J Biol Chem , vol.283 , pp. 8034-8045
    • Wang, P.Y.1    Weng, J.2    Lee, S.3    Anderson, R.G.4
  • 240
    • 0027167918 scopus 로고
    • Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization
    • Wang X, Briggs MR, Hua X, Yokoyama C, Goldstein JL, Brown MS (1993) Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization. J Biol Chem 268 : 14497-14504
    • (1993) J Biol Chem , vol.268 , pp. 14497-14504
    • Wang, X.1    Briggs, M.R.2    Hua, X.3    Yokoyama, C.4    Goldstein, J.L.5    Brown, M.S.6
  • 241
    • 55549139504 scopus 로고    scopus 로고
    • Regulation of cholesterologenesis by the oxysterol receptor, LXR a
    • Wang Y, Rogers P, Su C, Varga G, Stayrook KR, Burris TP (2008b) Regulation of cholesterologenesis by the oxysterol receptor, LXR a. J Biol Chem 283 : 26332-26339
    • (2008) J Biol Chem , vol.283 , pp. 26332-26339
    • Wang, Y.1    Rogers, P.2    Su, C.3    Varga, G.4    Stayrook, K.R.5    Burris, T.P.6
  • 242
    • 0041666303 scopus 로고    scopus 로고
    • 27-Hydroxylation of 7- And 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: A novel metabolic pathway
    • Wassif CA, Yu J, Cui J, Porter FD, Javitt NB (2003) 27-Hydroxylation of 7- And 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: A novel metabolic pathway. Steroids 68 : 497-502
    • (2003) Steroids , vol.68 , pp. 497-502
    • Wassif, C.A.1    Yu, J.2    Cui, J.3    Porter, F.D.4    Javitt, N.B.5
  • 243
    • 0035007094 scopus 로고    scopus 로고
    • Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins
    • Vaya J, Aviram M, Mahmood S, Hayek T, Grenadir E, Hoffman A, Milo S (2001) Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins. Free Radic Res 34 : 485-497
    • (2001) Free Radic Res , vol.34 , pp. 485-497
    • Vaya, J.1    Aviram, M.2    Mahmood, S.3    Hayek, T.4    Grenadir, E.5    Hoffman, A.6    Milo, S.7
  • 244
    • 0034640288 scopus 로고    scopus 로고
    • Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols
    • Venkateswaran A, Repa JJ, Lobaccaro JM, Bronson A, Mangelsdorf DJ, Edwards PA (2000) Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols. J Biol Chem 275 : 14700-14707
    • (2000) J Biol Chem , vol.275 , pp. 14700-14707
    • Venkateswaran, A.1    Repa, J.J.2    Lobaccaro, J.M.3    Bronson, A.4    Mangelsdorf, D.J.5    Edwards, P.A.6
  • 246
    • 10644229420 scopus 로고    scopus 로고
    • Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux
    • Wong J, Quinn CM, Brown AJ (2004) Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux. Arterioscler Thromb Vasc Biol 24 : 2365-2371
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2365-2371
    • Wong, J.1    Quinn, C.M.2    Brown, A.J.3
  • 247
    • 34247381583 scopus 로고    scopus 로고
    • Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol
    • Wong J, Quinn CM, Brown AJ (2007a) Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol. Lipids Health Dis 6 : 10
    • (2007) Lipids Health Dis , vol.6 , pp. 10
    • Wong, J.1    Quinn, C.M.2    Brown, A.J.3
  • 248
    • 36249006573 scopus 로고    scopus 로고
    • Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis
    • Wong J, Quinn CM, Guillemin G, Brown AJ (2007b) Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis. J Neurochem 103 : 1764-1773
    • (2007) J Neurochem , vol.103 , pp. 1764-1773
    • Wong, J.1    Quinn, C.M.2    Guillemin, G.3    Brown, A.J.4
  • 249
    • 38149138153 scopus 로고    scopus 로고
    • Endogenous 24(S),25-epoxycholesterol fine-Tunes acute control of cellular cholesterol homeostasis
    • Wong J, Quinn CM, Gelissen IC, Brown AJ (2008) Endogenous 24(S),25-epoxycholesterol fine-Tunes acute control of cellular cholesterol homeostasis. J Biol Chem 283 : 700-707
    • (2008) J Biol Chem , vol.283 , pp. 700-707
    • Wong, J.1    Quinn, C.M.2    Gelissen, I.C.3    Brown, A.J.4
  • 250
    • 2942703761 scopus 로고    scopus 로고
    • VAMP-Associated protein-A regulates partitioning of oxysterolbinding protein-related protein-9 between the endoplasmic reticulum and Golgi apparatus
    • Wyles JP, Ridgway ND (2004) VAMP-Associated protein-A regulates partitioning of oxysterolbinding protein-related protein-9 between the endoplasmic reticulum and Golgi apparatus. Exp Cell Res 297 : 533-547
    • (2004) Exp Cell Res , vol.297 , pp. 533-547
    • Wyles, J.P.1    Ridgway, N.D.2
  • 251
    • 0037119364 scopus 로고    scopus 로고
    • Vesicle-Associated membrane protein-Associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum
    • Wyles JP, McMaster CR, Ridgway ND (2002) Vesicle-Associated membrane protein-Associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum. J Biol Chem 277 : 29908-29918
    • (2002) J Biol Chem , vol.277 , pp. 29908-29918
    • Wyles, J.P.1    McMaster, C.R.2    Ridgway, N.D.3
  • 252
    • 33947719759 scopus 로고    scopus 로고
    • Characterization of the sterol-binding domain of oxysterolbinding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization
    • Wyles JP, Perry RJ, Ridgway ND (2007) Characterization of the sterol-binding domain of oxysterolbinding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization. Exp Cell Res 313 : 1426-1437
    • (2007) Exp Cell Res , vol.313 , pp. 1426-1437
    • Wyles, J.P.1    Perry, R.J.2    Ridgway, N.D.3
  • 253
    • 0035947559 scopus 로고    scopus 로고
    • Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport
    • Xu Y, Liu Y, Ridgway ND, McMaster CR (2001) Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport. J Biol Chem 276 : 18407-18414
    • (2001) J Biol Chem , vol.276 , pp. 18407-18414
    • Xu, Y.1    Liu, Y.2    Ridgway, N.D.3    McMaster, C.R.4
  • 254
    • 0036792050 scopus 로고    scopus 로고
    • Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
    • Yabe D, Brown MS, Goldstein JL (2002) Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins. Proc Natl Acad Sci USA 99 : 12753-12758
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12753-12758
    • Yabe, D.1    Brown, M.S.2    Goldstein, J.L.3
  • 255
    • 38949137379 scopus 로고    scopus 로고
    • Characteristics of oxysterol binding proteins
    • Yan D, Olkkonen VM (2008) Characteristics of oxysterol binding proteins. Int Rev Cytol 265 : 253-285
    • (2008) Int Rev Cytol , vol.265 , pp. 253-285
    • Yan, D.1    Olkkonen, V.M.2
  • 259
    • 0036329207 scopus 로고    scopus 로고
    • Activity of specific lipid-regulated ADP ribosylation factor-GTPaseactivating proteins is required for Sec14p-dependent Golgi secretory function in yeast
    • Yanagisawa LL, Marchena J, Xie Z, Li X, Poon PP, Singer RA, Johnston GC, Randazzo PA, Bankaitis VA (2002) Activity of specific lipid-regulated ADP ribosylation factor-GTPaseactivating proteins is required for Sec14p-dependent Golgi secretory function in yeast. Mol Biol Cell 13 : 2193-206
    • (2002) Mol Biol Cell , vol.13 , pp. 2193-206
    • Yanagisawa, L.L.1    Marchena, J.2    Xie, Z.3    Li, X.4    Poon, P.P.5    Singer, R.A.6    Johnston, G.C.7    Randazzo, P.A.8    Bankaitis, V.A.9
  • 260
    • 0037162719 scopus 로고    scopus 로고
    • Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
    • Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, Brown MS (2002) Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110 : 489-500
    • (2002) Cell , vol.110 , pp. 489-500
    • Yang, T.1    Espenshade, P.J.2    Wright, M.E.3    Yabe, D.4    Gong, Y.5    Aebersold, R.6    Goldstein, J.L.7    Brown, M.S.8
  • 261
    • 0842286545 scopus 로고    scopus 로고
    • Deletion of OSH3 gene confers resistance against ISP-1 in Saccharomyces cerevisiae
    • Yano T, Inukai M, Isono F (2004) Deletion of OSH3 gene confers resistance against ISP-1 in Saccharomyces cerevisiae. Biochem Biophys Res Commun 315 : 228-234
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 228-234
    • Yano, T.1    Inukai, M.2    Isono, F.3
  • 262
    • 0035091665 scopus 로고    scopus 로고
    • Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against oxidized low-density lipoprotein and oxysterols
    • Yasunobu Y, Hayashi K, Shingu T, Yamagata T, Kajiyama G, Kambe M (2001) Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against oxidized low-density lipoprotein and oxysterols. Atherosclerosis 155 : 445-453
    • (2001) Atherosclerosis , vol.155 , pp. 445-453
    • Yasunobu, Y.1    Hayashi, K.2    Shingu, T.3    Yamagata, T.4    Kajiyama, G.5    Kambe, M.6
  • 263
    • 0027490174 scopus 로고
    • SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
    • Yokoyama C, Wang X, Briggs MR, Admon A, Wu J, Hua X, Goldstein JL, Brown MS (1993) SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell 75 : 187-197
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8
  • 265
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • Zelcer N, Tontonoz P (2006) Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest 116 : 607-614
    • (2006) J Clin Invest , vol.116 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 266
    • 33745177734 scopus 로고    scopus 로고
    • Two distinct oxysterol binding protein-related proteins in the parasitic protist Cryptosporidium parvum (Apicomplexa
    • Zeng B, Zhu G (2006) Two distinct oxysterol binding protein-related proteins in the parasitic protist Cryptosporidium parvum (Apicomplexa). Biochem Biophys Res Commun 346 : 591-399
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 591-399
    • Zeng, B.1    Zhu, G.2
  • 268
    • 0033993486 scopus 로고    scopus 로고
    • An excess concentration of oxysterols in the plasma is cytotoxic to cultured endothelial cells
    • Zhou Q, Wasowicz E, Handler B, Fleischer L, Kummerow FA (2000) An excess concentration of oxysterols in the plasma is cytotoxic to cultured endothelial cells. Atherosclerosis 149 : 191-197
    • (2000) Atherosclerosis , vol.149 , pp. 191-197
    • Zhou, Q.1    Wasowicz, E.2    Handler, B.3    Fleischer, L.4    Kummerow, F.A.5
  • 270
    • 0026082909 scopus 로고
    • Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae
    • Zinser E, Sperka-Gottlieb CD, Fasch EV, Kohlwein SD, Paltauf F, Daum G (1991) Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. J Bacteriol 173 : 2026-2034
    • (1991) J Bacteriol , vol.173 , pp. 2026-2034
    • Zinser, E.1    Sperka-Gottlieb, C.D.2    Fasch, E.V.3    Kohlwein, S.D.4    Paltauf, F.5    Daum, G.6


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