The Hypocholesterolemic Agent LY295427 Reverses Suppression of Sterol Regulatory Element-binding Protein Processing Mediated by Oxysterols

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 45408-45416

  Janowski, Bethany A ^a   Shan, Bei ^b   Russell, David W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHOLESTEROL; DNA; ENZYME INHIBITION; ESTERS; GENES; METABOLISM; PROTEINS; RNA;

MICROMOLAR CONCENTRATION;

BIOCHEMISTRY;

4ALPHA ALLYL 5ALPHA CHOLESTAN 3ALPHA OL; CHOLESTEROL ESTER; COMPLEMENTARY DNA; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN RECEPTOR; LY 306039; OXYSTEROL; PROTEINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNCLASSIFIED DRUG; 25 HYDROXYCHOLESTEROL; 25-HYDROXYCHOLESTEROL; CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEINS; CHOLESTANOL; CHOLESTEROL; CHOLESTEROL DERIVATIVE; DNA BINDING PROTEIN; DNA BINDING PROTEINS; LOW DENSITY LIPOPROTEIN; RNA; SPHINGOMYELIN PHOSPHODIESTERASE; SRE 1 BINDING PROTEIN; SRE-1 BINDING PROTEIN; STEROID; TRIACYLGLYCEROL;

ANIMAL CELL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; DNA MICROARRAY; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; HUMAN CELL; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN PROCESSING; ANIMAL; BLOOD; CELL CULTURE; CELL LINE; CELL NUCLEUS; CHEMICAL MODEL; CHEMISTRY; CHO CELL; FIBROBLAST; HAMSTER; IMMUNOBLOTTING; METABOLISM; PROTEIN BINDING; TIME;

ANIMALIA;

ANIMAL; ANTICHOLESTEREMIC AGENTS; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CELL NUCLEUS; CELLS, CULTURED; CHO CELLS; CHOLESTANOLS; CHOLESTEROL; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; FIBROBLASTS; HAMSTERS; HUMAN; HYDROXYCHOLESTEROLS; IMMUNOBLOTTING; LIPOPROTEINS, LDL; MODELS, CHEMICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; RNA; SPHINGOMYELIN PHOSPHODIESTERASE; STEROIDS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS; TRIGLYCERIDES;

EID: 0035976936     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108348200     Document Type: Article

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