Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain

Biochemical Journal

Volumn 326, Issue 1, 1997, Pages 205-213

  Lagace, Thomas A ^a   Byers, David M ^a   Cook, Harold W ^a   Ridgway, Neale D ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYCHOLESTEROL; BINDING PROTEIN; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PLECKSTRIN; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CHO CELL; CHOLESTEROL ESTERIFICATION; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; ENZYME ACTIVITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GOLGI COMPLEX; IMMUNOFLUORESCENCE; METABOLIC REGULATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; RABBIT;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; ORYCTOLAGUS CUNICULUS;

EID: 0030882949     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3260205     Document Type: Article

References (40)

1. Hwang, P. L. (1991) BioEssays 13, 583-589
2. Smith, L. L. (1996) Lipids 31, 453-487
3. Kandutsch, A. A., Chen, H. W. and Heiniger, H.-J. (1978) Science 201, 498-501
4. Goldstein, J. L. and Brown, M. S. (1990) Nature (London) 343, 425-430
5. Taylor, F. R. and Kandutsch, A. A. (1985) Methods Enzymol. 110, 9-19
6. Kandutsch, A. A. and Shown, E. P. (1981) J. Biol. Chem. 256, 13068-13073
7. Taylor, F. R., Saucier, S. E., Shown, E. P., Parish, E. J. and Kandutsch, A. A. (1984) J. Biol. Chem. 259, 12384-12387
8. Levanon, D., Hsieh, C.-L., Franke, U., Dawson, P. A., Ridgway, N. D., Brown, M. S. and Goldstein, J. L. (1990) Genomics 7, 65-74
9. Dawson, P. A., Ridgway, N. D., Slaughter, C. A., Brown, M. S. and Goldstein, J. L. (1989) J. Biol. Chem. 264, 16798-16803
10. Dawson, P. A., Van Der Wethuyzen, D. R., Goldstein, J. L. and Brown, M. S. (1989) J. Biol. Chem. 264, 9046-9052
11. Ridgway, N. D., Dawson, P. A., Ho, Y. K., Brown, M. S. and Goldstein, J. L. (1992) J. Cell Biol. 116, 307-319
12. Gibson, T. J., Hyvonen, M., Musacchio, A. and Saraste, M. (1994) Trends Biochem. Sci. 19, 349-353
13. Haslam, R. J., Kolde, H. B. and Hemmings, B. A. (1993) Nature (London) 363, 309-310
14. Jiang, B., Brown, J. L., Sheraton, J., Fortin, N. and Bussey, H. (1994) Yeast 10, 341-353
15. Fang, M., Kearns, B. G., Gedvitaite, A., Kagiwada, S., Kearns, M., Fung, M. K. Y. and Bankaitis, V. A. (1996) EMBO J. 15, 6447-6459
16. Esser, V., Limbird, L. E., Brown, M. S., Goldstein, J. L. and Russell, D. W. (1988) J. Biol. Chem. 263, 13283-13290
17. Goldstein, J. L., Basu, S. K. and Brown, M. S. (1983) Methods Enzymol. 98, 241-260
18. Metherall, J. E., Ridgway, N. D., Dawson, P. A., Goldstein, J. L. and Brown, M. S. (1991) J. Biol. Chem. 266, 12734-12740
19. Ridgway, N. D. and Lagace, T. A. (1995) J. Biol. Chem. 270, 8023-8031
20. Cao, G., Goldstein, J. L. and Brown, M. S. (1996) J. Biol. Chem. 271, 14642-14648
21. Brown, M. S., Faust, J. R., Goldstein, J. L., Kandeko, I. and Endo, A. (1978) J. Biol. Chem. 253, 1121-1128
22. Brown, M. S., Dana, S. E. and Goldstein, J. L. (1975) J. Biol. Chem. 250, 4025-5027
23. Cheng, D., Chang, C. C. Y., Qu, X. M. and Chang, T. Y. (1995) J. Biol. Chem. 270, 685-695
24. Myant, N. B. (1990) in Cholesterol Metabolism, LDL and LDL Receptor, (Myant, N. B., ed.), pp. 85-98, Academic Press, San Diego
25. Inglese, J., Koch, J. W., Kazushige, T. and Lefkowitz, R. J. (1995) Trends Biochem. Sci. 20, 151-156
26. Lemmon, M. A., Ferguson, K. M. and Schlessinger, J. (1996) Cell 85, 621-624
27. Uleman, P. J., Oka, K., Sullivan, M., Chang, C. C. Y., Chang, T. Y. and Chan, L. (1995) J. Biol. Chem. 270, 26192-26201
28. Ferguson, K. M., Lemmon, M. A., Schlessinger, J. and Sigler, P. B. (1994) Cell 79, 199-209
29. Yoon, S.-H., Hadjuk, P. J., Petros, A. M., Olejniczak, E. T., Meadows, R. P. and Fesik, S. W. (1994) Nature (London) 369, 672-677
30. Ferguson, K. M., Lemmon, M. A., Schlessinger, J. and Sigler, P. B. (1995) Cell 83, 1037-1046
31. Touhara, K., Inglese, J., Pitcher, J. A., Shaw, G. and Lefkowitz, R. J. (1994) J. Biol. Chem. 269, 10217-10220
32. Touhara, K., Koch, W. J., Hawes, B. E. and Lefkowitz, R. J. (1995) J. Biol. Chem. 270, 17000-17005
33. Yao, L., Kawakami, Y. and Kawakami, T. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 9175-9179
34. Konishi, H., Kuroda, S. and Kikkawa, U. (1994) Biochem. Biophys. Res. Commun. 205, 1770-1775
35. Wang, D. S., Shaw, R., Hattori, M., Arai, H., Inoue, K. and Shaw, G. (1995) Biochem. Biophys. Res. Commun. 209, 622-629
36. Paterson, H. F., Savopoulos, J. W., Perisisc, O., Cheung, R., Ellis, M. V., Williams, R. L. and Katan, M. (1995) Biochem. J. 312, 661-666
37. Essen, L. O., Pewrisic, O., Cheung, R., Katan, M. and Williams, R. L. (1996) Nature (London) 380, 595-602
38. Lemmon, M. A., Ferguson, K. M., O'Brien, R., Sigler, P. B. and Schlessinger, J. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 10472-10476
39. Hyvönen, M., Macias, M. J., Nilges, M., Oschkinat, H., Saraste, M. and Wilmanns, M. (1995) EMBO J. 14, 4676-4685
40. Harlan, J. E., Hadjuk, P. J., Yoon, H.-S. and Fesik, S. W. (1994) Nature (London) 371, 168-170