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Volumn 39, Issue 5, 2007, Pages 359-370

Cytochrome P450 - Physiological key factor against cholesterol accumulation and the atherosclerotic vascular process

Author keywords

ABC transporter; Apolipoprotein AI; CYP; Cytochrome P450; Gene activation; HDL; Induction; LXR; Oxysterol; PPAR

Indexed keywords

ABC TRANSPORTER; ADENOSINE A2 RECEPTOR AGONIST; ANTICONVULSIVE AGENT; APOLIPOPROTEIN; BEZAFIBRATE; COLECALCIFEROL RECEPTOR; COLESTYRAMINE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; FARNESOID X RECEPTOR; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GAMMA INTERFERON; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; KETOCONAZOLE; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MEVINOLIN; OXYSTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHENOBARBITAL; PIOGLITAZONE; PITAVASTATIN; PREGNANE X RECEPTOR; RETINOL DERIVATIVE; ROSIGLITAZONE; SIMVASTATIN; STEROID; THIAZIDE DIURETIC AGENT;

EID: 34547887264     PISSN: 07853890     EISSN: 16512219     Source Type: Journal    
DOI: 10.1080/07853890701379767     Document Type: Review
Times cited : (25)

References (157)
  • 1
    • 50449100139 scopus 로고
    • The carbon-monoxide-binding pigment in liver microsomes. II. Solubilization, purification and properties
    • Omura T, Sato R. The carbon-monoxide-binding pigment in liver microsomes. II. Solubilization, purification and properties. J Biol Chem. 1964;239:2379-85.
    • (1964) J Biol Chem , vol.239 , pp. 2379-2385
    • Omura, T.1    Sato, R.2
  • 2
    • 0037068964 scopus 로고    scopus 로고
    • Clinical importance of the cytochromes P450
    • Nebert DW, Russell DW. Clinical importance of the cytochromes P450. Lancet. 2002;360:1155-62.
    • (2002) Lancet , vol.360 , pp. 1155-1162
    • Nebert, D.W.1    Russell, D.W.2
  • 3
    • 0018832516 scopus 로고
    • Plasma high density lipoprotein cholesterol and hepatic cytochrome P-450 concentrations in epileptics undergoing anticonvulsant treatment
    • Luoma PV, Sotaniemi EA, Pelkonen RO, Myllylä VV. Plasma high density lipoprotein cholesterol and hepatic cytochrome P-450 concentrations in epileptics undergoing anticonvulsant treatment. Scand J Clin Lab Invest. 1980;40:163-7.
    • (1980) Scand J Clin Lab Invest , vol.40 , pp. 163-167
    • Luoma, P.V.1    Sotaniemi, E.A.2    Pelkonen, R.O.3    Myllylä, V.V.4
  • 5
    • 0019977717 scopus 로고
    • Plasma high density lipoproteins and hepatic microsomal induction - relation to histological changes in the liver
    • Luoma PV, Sotaniemi EA, Pelkonen RO, Arranto A, Ehnholm C. Plasma high density lipoproteins and hepatic microsomal induction - relation to histological changes in the liver. Eur J Clin Pharmacol. 1982;23:275-82.
    • (1982) Eur J Clin Pharmacol , vol.23 , pp. 275-282
    • Luoma, P.V.1    Sotaniemi, E.A.2    Pelkonen, R.O.3    Arranto, A.4    Ehnholm, C.5
  • 6
    • 0021090010 scopus 로고
    • Inverse relation of serum LDL cholesterol and the LDL/HDL cholesterol ratio to liver microsomal induction in man
    • Luoma PV, Sotaniemi EA, Pelkonen RO. Inverse relation of serum LDL cholesterol and the LDL/HDL cholesterol ratio to liver microsomal induction in man. Res Commun Chem Pathol Pharmacol. 1983;42:173-6.
    • (1983) Res Commun Chem Pathol Pharmacol , vol.42 , pp. 173-176
    • Luoma, P.V.1    Sotaniemi, E.A.2    Pelkonen, R.O.3
  • 7
    • 0021017278 scopus 로고
    • Serum LDL cholesterol and LDL/HDL cholesterol ratio and liver microsomal induction evaluated by antipyrine kinetics
    • Luoma PV, Sotaniemi EA, Arranto AJ. Serum LDL cholesterol and LDL/HDL cholesterol ratio and liver microsomal induction evaluated by antipyrine kinetics. Scand J Clin Lab Invest. 1983;43:671-5.
    • (1983) Scand J Clin Lab Invest , vol.43 , pp. 671-675
    • Luoma, P.V.1    Sotaniemi, E.A.2    Arranto, A.J.3
  • 9
  • 10
    • 0028068796 scopus 로고
    • Atherosclerosis and sterol 27-hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages
    • Björkhem I, Andersson O, Diczfalusy U, Sefastik B, Xiu R-J, Duan C, et al. Atherosclerosis and sterol 27-hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages. Proc Natl Acad Sci U S A. 1994;91:8592-6.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 8592-8596
    • Björkhem, I.1    Andersson, O.2    Diczfalusy, U.3    Sefastik, B.4    Xiu, R.-J.5    Duan, C.6
  • 12
    • 0032892176 scopus 로고    scopus 로고
    • Removal of cholesterol from extrahepatic sources by oxidative mechanisms
    • Björkhem I, Diczfalusy U, Lütjohann D. Removal of cholesterol from extrahepatic sources by oxidative mechanisms. Curr Opin Lipidol. 1999;10:161-5.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 161-165
    • Björkhem, I.1    Diczfalusy, U.2    Lütjohann, D.3
  • 13
    • 0034693064 scopus 로고    scopus 로고
    • Specific binding of apoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABCA1
    • Wang N, Silver DL, Costet P, Tall AR. Specific binding of apoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABCA1. J Biol Chem. 2000;275:33053-8.
    • (2000) J Biol Chem , vol.275 , pp. 33053-33058
    • Wang, N.1    Silver, D.L.2    Costet, P.3    Tall, A.R.4
  • 14
    • 3042798281 scopus 로고    scopus 로고
    • ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins
    • Wang N, Lan D, Chen W, Matsuura F, Tall AR. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc Natl Acad Sci U S A. 2004;101:9774-9.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9774-9779
    • Wang, N.1    Lan, D.2    Chen, W.3    Matsuura, F.4    Tall, A.R.5
  • 15
    • 12944286618 scopus 로고    scopus 로고
    • ABCG1 (ABC8), the human homolog of the drosophila white gene, is regulator of macrophage cholesterol and phospholipid transport
    • Klucken J, Büchler C, Orsó E, Kaminski WE, Porsch-Özcrmez M, Liebisch G, et al. ABCG1 (ABC8), the human homolog of the drosophila white gene, is regulator of macrophage cholesterol and phospholipid transport. Proc Natl Acad Sci U S A. 2000;97:817-22.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 817-822
    • Klucken, J.1    Büchler, C.2    Orsó, E.3    Kaminski, W.E.4    Porsch-Özcrmez, M.5    Liebisch, G.6
  • 16
    • 0030787747 scopus 로고    scopus 로고
    • Gene activation, apolipoprotein A-I/ high density lipoprotein, atherosclerosis prevention and longevity
    • Luoma PV. Gene activation, apolipoprotein A-I/ high density lipoprotein, atherosclerosis prevention and longevity. Pharmacol Toxicol. 1997;81:57-64.
    • (1997) Pharmacol Toxicol , vol.81 , pp. 57-64
    • Luoma, P.V.1
  • 17
    • 0020559718 scopus 로고
    • Plasma high density lipoprotein and liver lipids and proteins in man. Relation to hepatic histology and microsomal enzyme induction
    • Luoma PV, Savolainen MJ, Sotaniemi EA, Pelkonen RO, Arranto AJ, Ehnholm C. Plasma high density lipoprotein and liver lipids and proteins in man. Relation to hepatic histology and microsomal enzyme induction. Acta Med Scand. 1983;214:103-9.
    • (1983) Acta Med Scand , vol.214 , pp. 103-109
    • Luoma, P.V.1    Savolainen, M.J.2    Sotaniemi, E.A.3    Pelkonen, R.O.4    Arranto, A.J.5    Ehnholm, C.6
  • 19
    • 0022375805 scopus 로고
    • Effect of alcohol intake on high and low density lipoprotein metabolism in healthy volunteers
    • Malmendier CL, Delcroix C. Effect of alcohol intake on high and low density lipoprotein metabolism in healthy volunteers. Clinica Chimica Acta. 1985;152:281-8.
    • (1985) Clinica Chimica Acta , vol.152 , pp. 281-288
    • Malmendier, C.L.1    Delcroix, C.2
  • 20
    • 0021868786 scopus 로고
    • Effects of fenofibrate on high and low density lipoprotein metabolism in heterozygous familial hypercholesterolemia
    • Malmendier C, Delcroix C. Effects of fenofibrate on high and low density lipoprotein metabolism in heterozygous familial hypercholesterolemia. Atherosclerosis. 1985;55:161-9.
    • (1985) Atherosclerosis , vol.55 , pp. 161-169
    • Malmendier, C.1    Delcroix, C.2
  • 21
    • 0021824527 scopus 로고
    • Mechanism of action of gemfibrozil on lipoprotein metabolism
    • Saku K, Gartside PS, Hynd BA, Kashyap ML. Mechanism of action of gemfibrozil on lipoprotein metabolism. J Clin Invest. 1985;75:1702-12.
    • (1985) J Clin Invest , vol.75 , pp. 1702-1712
    • Saku, K.1    Gartside, P.S.2    Hynd, B.A.3    Kashyap, M.L.4
  • 22
    • 0025946372 scopus 로고
    • Effects of gemfibrozil and ketoconazole on human apolipoprotein A-I and E levels in two hepatoma cell lines HepG2 and HepG3
    • Tam SP. Effects of gemfibrozil and ketoconazole on human apolipoprotein A-I and E levels in two hepatoma cell lines HepG2 and HepG3. Atherosclerosis. 1991;91:51-61.
    • (1991) Atherosclerosis , vol.91 , pp. 51-61
    • Tam, S.P.1
  • 23
    • 0027052280 scopus 로고
    • Effect of ethanol on lipoprotein secretion in two human hepatoma cell lines HepG2 and HepG3
    • Tam SP. Effect of ethanol on lipoprotein secretion in two human hepatoma cell lines HepG2 and HepG3. Alcohol Clin Exp Res. 1992;16:1021-8.
    • (1992) Alcohol Clin Exp Res , vol.16 , pp. 1021-1028
    • Tam, S.P.1
  • 24
    • 0025902231 scopus 로고
    • Inhibition of early atherogenesis in transgenic mice by human apoprotein A-I
    • Rubin EM, Krauss MR, Spangler EA, Verstuyft JG, Clift MS. Inhibition of early atherogenesis in transgenic mice by human apoprotein A-I. Nature. 1991;353:265-7.
    • (1991) Nature , vol.353 , pp. 265-267
    • Rubin, E.M.1    Krauss, M.R.2    Spangler, E.A.3    Verstuyft, J.G.4    Clift, M.S.5
  • 25
    • 9544221670 scopus 로고    scopus 로고
    • Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-I transgenic rabbits
    • Duverger N, Kruth NH, Emmanuel F, Caillaud JM, Viglietta C, Castro G, et al. Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-I transgenic rabbits. Circulation. 1996;94:713-7.
    • (1996) Circulation , vol.94 , pp. 713-717
    • Duverger, N.1    Kruth, N.H.2    Emmanuel, F.3    Caillaud, J.M.4    Viglietta, C.5    Castro, G.6
  • 26
    • 0033543084 scopus 로고    scopus 로고
    • Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans
    • Eriksson M, Carlson LA, Miettinen TA, Angelin B. Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans. Circulation. 1999;100:594-8.
    • (1999) Circulation , vol.100 , pp. 594-598
    • Eriksson, M.1    Carlson, L.A.2    Miettinen, T.A.3    Angelin, B.4
  • 27
    • 0034672672 scopus 로고    scopus 로고
    • Oxysterol biosynthetic enzymes
    • Russell DW. Oxysterol biosynthetic enzymes. Biochim Biophys Acta. 2000;1529:126-35.
    • (2000) Biochim Biophys Acta , vol.1529 , pp. 126-135
    • Russell, D.W.1
  • 28
    • 0037503924 scopus 로고    scopus 로고
    • Liver X receptors signalling pathways in cardiovascular disease
    • Tontonoz P, Mangelsdorf DJ. Liver X receptors signalling pathways in cardiovascular disease. Mol Endocrinol. 2003;17:985-93.
    • (2003) Mol Endocrinol , vol.17 , pp. 985-993
    • Tontonoz, P.1    Mangelsdorf, D.J.2
  • 29
    • 4944247161 scopus 로고    scopus 로고
    • Nuclear receptor signalling in the control of cholesterol homeostasis: Have the orphans found a home
    • Ory DS. Nuclear receptor signalling in the control of cholesterol homeostasis: have the orphans found a home. Circ Res. 2004;95:660-70.
    • (2004) Circ Res , vol.95 , pp. 660-670
    • Ory, D.S.1
  • 30
    • 0037790917 scopus 로고    scopus 로고
    • The enzymes, regulation and genetics of bile acid synthesis
    • Russell DW. The enzymes, regulation and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72:137-74.
    • (2003) Annu Rev Biochem , vol.72 , pp. 137-174
    • Russell, D.W.1
  • 32
    • 0035914330 scopus 로고    scopus 로고
    • 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol loaded cells
    • Fu X, Menke JG, Chen Y, Zhou G, MacNaul KL, Wright SD, et al. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol loaded cells. J Biol Chem. 2001;276:38378-87.
    • (2001) J Biol Chem , vol.276 , pp. 38378-38387
    • Fu, X.1    Menke, J.G.2    Chen, Y.3    Zhou, G.4    MacNaul, K.L.5    Wright, S.D.6
  • 33
    • 0038175529 scopus 로고    scopus 로고
    • Expression of sterol 27-hydroxylase (CYP27A1) enhances cholesterol efflux
    • Escher G, Krozowski Z, Croft KD, Sviridov D. Expression of sterol 27-hydroxylase (CYP27A1) enhances cholesterol efflux. J Biol Chem. 2003;278:11015-9.
    • (2003) J Biol Chem , vol.278 , pp. 11015-11019
    • Escher, G.1    Krozowski, Z.2    Croft, K.D.3    Sviridov, D.4
  • 34
    • 0034602245 scopus 로고    scopus 로고
    • Oxysterol 7α-hydroxylase activity by cholesterol 7α-hydroxylase (CYP7A)
    • Norlin M, Andersson U, Björkhem I, Wikwall K. Oxysterol 7α-hydroxylase activity by cholesterol 7α-hydroxylase (CYP7A). J Biol Chem. 2000;275:34046-53.
    • (2000) J Biol Chem , vol.275 , pp. 34046-34053
    • Norlin, M.1    Andersson, U.2    Björkhem, I.3    Wikwall, K.4
  • 35
    • 2442557294 scopus 로고    scopus 로고
    • Brain cholesterol: Long secret life behind a barrier
    • Björkhem I, Meaney S. Brain cholesterol: long secret life behind a barrier. Arterioscler Thromb Vasc Biol. 2004;24:806-15.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 806-815
    • Björkhem, I.1    Meaney, S.2
  • 36
    • 3543104951 scopus 로고    scopus 로고
    • Cholesterol metabolism in the central nervous system during early development and in the mature animal
    • Dietschy JM, Turley SD. Cholesterol metabolism in the central nervous system during early development and in the mature animal. J Lipid Res. 2004;45:1375-97.
    • (2004) J Lipid Res , vol.45 , pp. 1375-1397
    • Dietschy, J.M.1    Turley, S.D.2
  • 37
    • 0029835410 scopus 로고    scopus 로고
    • Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into circulation
    • Lütjohann D, Breuer O, Ahlborg G, Nennesmo I, Sidén Å, Diczfalusy U, et al. Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into circulation. Proc Natl Acad Sci U S A. 1996;93:9799-804.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9799-9804
    • Lütjohann, D.1    Breuer, O.2    Ahlborg, G.3    Nennesmo, I.4    Sidén, A.5    Diczfalusy, U.6
  • 38
    • 0034595650 scopus 로고    scopus 로고
    • Expression cloning of an oxysterol 7α-hydroxylase selective for 24-hydroxycholesterol
    • Li-Hawkins J, Lund EG, Bronson AD, Russell DW. Expression cloning of an oxysterol 7α-hydroxylase selective for 24-hydroxycholesterol. J Biol Chem. 2000;275:16543-48.
    • (2000) J Biol Chem , vol.275 , pp. 16543-16548
    • Li-Hawkins, J.1    Lund, E.G.2    Bronson, A.D.3    Russell, D.W.4
  • 39
    • 33744948883 scopus 로고    scopus 로고
    • 24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux
    • Abildayeva K, Jansen PJ, Hirsch-Reinshagen V, Bloks WV, Bakker AHF, Ramaekers FCS, et al. 24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux. J Biol Chem. 2006;281:12799-808.
    • (2006) J Biol Chem , vol.281 , pp. 12799-12808
    • Abildayeva, K.1    Jansen, P.J.2    Hirsch-Reinshagen, V.3    Bloks, W.V.4    Bakker, A.H.F.5    Ramaekers, F.C.S.6
  • 40
    • 0037230328 scopus 로고    scopus 로고
    • Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes
    • Pfrieger FW. Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes. Bioessays. 2002;25:72-8.
    • (2002) Bioessays , vol.25 , pp. 72-78
    • Pfrieger, F.W.1
  • 41
    • 0037044840 scopus 로고    scopus 로고
    • ABCA1 and scavenger receptor class B, type I, are modulators of reverse cholesterol transport at an in vitro blood-brain barrier constituted porcine brain capillary endothelial cells
    • Panzenboeck U, Balazs Z, Sovic A, Hrzenjak A, Levak-Frank S, Wintersperger A, et al. ABCA1 and scavenger receptor class B, type I, are modulators of reverse cholesterol transport at an in vitro blood-brain barrier constituted porcine brain capillary endothelial cells. J Biol Chem. 2002;277:42781-9.
    • (2002) J Biol Chem , vol.277 , pp. 42781-42789
    • Panzenboeck, U.1    Balazs, Z.2    Sovic, A.3    Hrzenjak, A.4    Levak-Frank, S.5    Wintersperger, A.6
  • 43
    • 0035914368 scopus 로고    scopus 로고
    • Antiepileptic drugs increase plasma levels of 4β-hydroxycholesterol in humans
    • Bodin K, Bretillon L, Aden Y, Bertilsson L, Broome U, Einarsson C, et al. Antiepileptic drugs increase plasma levels of 4β-hydroxycholesterol in humans. J Biol Chem. 2001;276:38685-9.
    • (2001) J Biol Chem , vol.276 , pp. 38685-38689
    • Bodin, K.1    Bretillon, L.2    Aden, Y.3    Bertilsson, L.4    Broome, U.5    Einarsson, C.6
  • 44
    • 0037413191 scopus 로고    scopus 로고
    • The role of cytochrome P450 in the regulation of cholesterol biosynthesis
    • Gibbons GF. The role of cytochrome P450 in the regulation of cholesterol biosynthesis. Lipids. 2002;37:1163-70.
    • (2002) Lipids , vol.37 , pp. 1163-1170
    • Gibbons, G.F.1
  • 45
    • 0026564767 scopus 로고
    • Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding
    • Ridgway ND, Dawson PA, Ho YK, Brown MS, Goldstein JL. Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding. J Cell Biol. 1992;116:307-19.
    • (1992) J Cell Biol , vol.116 , pp. 307-319
    • Ridgway, N.D.1    Dawson, P.A.2    Ho, Y.K.3    Brown, M.S.4    Goldstein, J.L.5
  • 46
    • 33745477974 scopus 로고    scopus 로고
    • The OSBP-related proteins (ORPS): Global sterol sensors for co-ordination of cellular lipid metabolism, membrane trafficking and signalling processes
    • Olkkonen VM, Johansson M, Suchanek M, Yan D, Hynynen R, Ehnholm C, et al. The OSBP-related proteins (ORPS): global sterol sensors for co-ordination of cellular lipid metabolism, membrane trafficking and signalling processes. Biochem Soc Transact. 2006;34:389-91.
    • (2006) Biochem Soc Transact , vol.34 , pp. 389-391
    • Olkkonen, V.M.1    Johansson, M.2    Suchanek, M.3    Yan, D.4    Hynynen, R.5    Ehnholm, C.6
  • 47
    • 33645727511 scopus 로고    scopus 로고
    • Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein related proteins and phosphoinositides
    • Raychaudhuri S, Im YJ, Hurley JH, Prinz WA. Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein related proteins and phosphoinositides. J Cell Biol. 2006;173:107-19.
    • (2006) J Cell Biol , vol.173 , pp. 107-119
    • Raychaudhuri, S.1    Im, Y.J.2    Hurley, J.H.3    Prinz, W.A.4
  • 48
    • 17744376173 scopus 로고    scopus 로고
    • A PPARγ- LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
    • Chawla A, Boisvert W, Lee C-H, Laffitte BA, Barak Y, Joseph SB, et al. A PPARγ- LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell. 2001;7:161-71.
    • (2001) Mol Cell , vol.7 , pp. 161-171
    • Chawla, A.1    Boisvert, W.2    Lee, C.-H.3    Laffitte, B.A.4    Barak, Y.5    Joseph, S.B.6
  • 49
    • 0032813809 scopus 로고    scopus 로고
    • The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
    • Bodzioch M, Orso E, Klucken J, Langmann T, Bottcher A, Diederich W, et al. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat Genet. 1999;22:347-51.
    • (1999) Nat Genet , vol.22 , pp. 347-351
    • Bodzioch, M.1    Orso, E.2    Klucken, J.3    Langmann, T.4    Bottcher, A.5    Diederich, W.6
  • 50
    • 0032813808 scopus 로고    scopus 로고
    • Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
    • Brooks-Wilson A, Marcil M, Clee SM, Zhang LH, Roomp K, van Dam M, et al. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat Genet. 1999;22:336-45.
    • (1999) Nat Genet , vol.22 , pp. 336-345
    • Brooks-Wilson, A.1    Marcil, M.2    Clee, S.M.3    Zhang, L.H.4    Roomp, K.5    van Dam, M.6
  • 51
    • 0032813660 scopus 로고    scopus 로고
    • Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
    • Rust S, Rosier M, Funke H, Real J, Amoura Z, Piett JC, et al. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat Genet. 1999;22:352-5.
    • (1999) Nat Genet , vol.22 , pp. 352-355
    • Rust, S.1    Rosier, M.2    Funke, H.3    Real, J.4    Amoura, Z.5    Piett, J.C.6
  • 52
    • 0032725185 scopus 로고    scopus 로고
    • The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway
    • Lawn RM, Wade DP, Garvin MR, Wang X, Schwartz K, Porter JG, et al. The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest. 1999;104:R25-31.
    • (1999) J Clin Invest , vol.104
    • Lawn, R.M.1    Wade, D.P.2    Garvin, M.R.3    Wang, X.4    Schwartz, K.5    Porter, J.G.6
  • 56
    • 5344253917 scopus 로고    scopus 로고
    • Regulation of plasma high-density lipoprotein levels by the ABCA1 transporter and the emerging role of high-density lipoprotein in the treatment of cardiovascular disease
    • Brewer HB Jr, Remaley AT, Neufeld EB, Basso F, Jouce C. Regulation of plasma high-density lipoprotein levels by the ABCA1 transporter and the emerging role of high-density lipoprotein in the treatment of cardiovascular disease. Arterioscler Thromb Vasc Biol. 2004;24:1755-60.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1755-1760
    • Brewer Jr, H.B.1    Remaley, A.T.2    Neufeld, E.B.3    Basso, F.4    Jouce, C.5
  • 57
    • 20944435724 scopus 로고    scopus 로고
    • Targeted inactivation of hepatic Abc 1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I
    • Timmins JM, Lee J-Y, Boydyguina E, Kluckman KD, Brunham LR, Mulya A, et al. Targeted inactivation of hepatic Abc 1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. J Clin Invest. 2005;115:1333-42.
    • (2005) J Clin Invest , vol.115 , pp. 1333-1342
    • Timmins, J.M.1    Lee, J.-Y.2    Boydyguina, E.3    Kluckman, K.D.4    Brunham, L.R.5    Mulya, A.6
  • 59
    • 0034284918 scopus 로고    scopus 로고
    • Regulation of absorption of ABCA1-mediated efflux of cholesterol by RXR heterodimers
    • Repa JJ, Turley SD, Lobaccaro JA, Medina J, Li L, Lustig K, et al. Regulation of absorption of ABCA1-mediated efflux of cholesterol by RXR heterodimers. Science. 2000;289:1524-9.
    • (2000) Science , vol.289 , pp. 1524-1529
    • Repa, J.J.1    Turley, S.D.2    Lobaccaro, J.A.3    Medina, J.4    Li, L.5    Lustig, K.6
  • 60
    • 0036733630 scopus 로고    scopus 로고
    • Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
    • Yu L, Li-Hawkins J, Hammer RE, Berge KE, Horton JD, Cohen JC, et al. Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest. 2002;110:671-80.
    • (2002) J Clin Invest , vol.110 , pp. 671-680
    • Yu, L.1    Li-Hawkins, J.2    Hammer, R.E.3    Berge, K.E.4    Horton, J.D.5    Cohen, J.C.6
  • 61
    • 11144257009 scopus 로고    scopus 로고
    • Increased fecal neutral steroid loss upon liver-X-receptor activation is independent of biliary sterol secretion in mice
    • Kruit JK, Plösch T, Havinga R, Boverhof R, Groot PEH, Groen AK, et al. Increased fecal neutral steroid loss upon liver-X-receptor activation is independent of biliary sterol secretion in mice. Gastroenterology. 2005;128:147-56.
    • (2005) Gastroenterology , vol.128 , pp. 147-156
    • Kruit, J.K.1    Plösch, T.2    Havinga, R.3    Boverhof, R.4    Groot, P.E.H.5    Groen, A.K.6
  • 62
    • 17744390348 scopus 로고    scopus 로고
    • Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
    • Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schutz J, et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science. 2000;290:1771-5.
    • (2000) Science , vol.290 , pp. 1771-1775
    • Berge, K.E.1    Tian, H.2    Graf, G.A.3    Yu, L.4    Grishin, N.V.5    Schutz, J.6
  • 63
    • 0035138625 scopus 로고    scopus 로고
    • PPARα and PPARγ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
    • Chinetti G, Lestavel S, Bocher V, Remaley AT, Neve B, Torra IP, et al. PPARα and PPARγ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med. 2001;7:53-8.
    • (2001) Nat Med , vol.7 , pp. 53-58
    • Chinetti, G.1    Lestavel, S.2    Bocher, V.3    Remaley, A.T.4    Neve, B.5    Torra, I.P.6
  • 64
    • 10044223533 scopus 로고    scopus 로고
    • and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis
    • Li AC, Glass CK. PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J Lipid Res. 2004;45:2161-73.
    • (2004) J Lipid Res , vol.45 , pp. 2161-2173
    • AC, L.1    Glass, C.P.2
  • 65
    • 0037199994 scopus 로고    scopus 로고
    • Regulated expression of the apolipoproteinE/C-I/C-IV/C-CII gene cluster in murine and human macrophage. A critical role for nuclear liver X receptors α and β
    • Mak PA, Laffitte BA, Resrumaux C, Joseph SB, Curtiss LK, Mangelsdorf DJ, et al. Regulated expression of the apolipoproteinE/C-I/C-IV/C-CII gene cluster in murine and human macrophage. A critical role for nuclear liver X receptors α and β. J Biol Chem. 2002;277:31900-8.
    • (2002) J Biol Chem , vol.277 , pp. 31900-31908
    • Mak, P.A.1    Laffitte, B.A.2    Resrumaux, C.3    Joseph, S.B.4    Curtiss, L.K.5    Mangelsdorf, D.J.6
  • 67
    • 3442895325 scopus 로고    scopus 로고
    • Liver X receptors (LXRs) regulate apolipoprotein AIV - implications of the antiatherosclerotic effect of LXR agonists
    • Liang Y, Jiang X-C, Liu R, Liang G, Beyer TP, Gao H, et al. Liver X receptors (LXRs) regulate apolipoprotein AIV - implications of the antiatherosclerotic effect of LXR agonists. Mol Endocrinol. 2004;18:2000-10.
    • (2004) Mol Endocrinol , vol.18 , pp. 2000-2010
    • Liang, Y.1    Jiang, X.-C.2    Liu, R.3    Liang, G.4    Beyer, T.P.5    Gao, H.6
  • 68
    • 0034669025 scopus 로고    scopus 로고
    • Regulation of mouse sterol regulatory element-binding protein-1c (SREBP-1c) by oxysterol receptors LXRα and LXRβ
    • Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JMA, Shimomura I, et al. Regulation of mouse sterol regulatory element-binding protein-1c (SREBP-1c) by oxysterol receptors LXRα and LXRβ. Genes Dev. 2000;14:2819-30.
    • (2000) Genes Dev , vol.14 , pp. 2819-2830
    • Repa, J.J.1    Liang, G.2    Ou, J.3    Bashmakov, Y.4    Lobaccaro, J.M.A.5    Shimomura, I.6
  • 69
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest. 2002;109:1125-31.
    • (2002) J Clin Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 70
    • 0038542910 scopus 로고    scopus 로고
    • Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes
    • Malerod L, Juvet LK, Hanssen-Bauer A, Eskild W, Berg T. Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes. Biochem Biophys Res Commun. 2002;299:916-23.
    • (2002) Biochem Biophys Res Commun , vol.299 , pp. 916-923
    • Malerod, L.1    Juvet, L.K.2    Hanssen-Bauer, A.3    Eskild, W.4    Berg, T.5
  • 71
    • 0030868610 scopus 로고    scopus 로고
    • Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux
    • Ji Y, Jian B, Wang N, Sun Y, de la Llera Moya M, Phillips MC, et al. Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux. J Biol Chem. 1997;272:20982-5.
    • (1997) J Biol Chem , vol.272 , pp. 20982-20985
    • Ji, Y.1    Jian, B.2    Wang, N.3    Sun, Y.4    de la Llera Moya, M.5    Phillips, M.C.6
  • 72
    • 9944247695 scopus 로고    scopus 로고
    • Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism
    • Eloranta JJ, Kullak-Ublick GA. Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism. Arch Biochem Biophys. 2005;433:397-412.
    • (2005) Arch Biochem Biophys , vol.433 , pp. 397-412
    • Eloranta, J.J.1    Kullak-Ublick, G.A.2
  • 73
    • 26244441014 scopus 로고    scopus 로고
    • The farnesoid X receptor - a molecular link between bile acid and lipid and glucose metabolism
    • Claudel T, Staels B, Kuipers F. The farnesoid X receptor - a molecular link between bile acid and lipid and glucose metabolism. Arterioscler Thromb Vasc Biol. 2005;25:2020-31.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2020-2031
    • Claudel, T.1    Staels, B.2    Kuipers, F.3
  • 74
    • 13644266845 scopus 로고    scopus 로고
    • Novel pathways of bile acid metabolism involving CYP3A4
    • Bodin K, Lindbom U, Diczfalusy U. Novel pathways of bile acid metabolism involving CYP3A4. Biochim Biophys Acta. 2005;1687:84-93.
    • (2005) Biochim Biophys Acta , vol.1687 , pp. 84-93
    • Bodin, K.1    Lindbom, U.2    Diczfalusy, U.3
  • 77
    • 0031026377 scopus 로고    scopus 로고
    • Hepatic microsomal enzyme induction, β-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil or bezafibrate in the CD rat
    • Amacher D, Beck D, Schomaker SJ, Kenny CV. Hepatic microsomal enzyme induction, β-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil or bezafibrate in the CD rat. Toxicol Appl Pharmacol. 1997;142:143-50.
    • (1997) Toxicol Appl Pharmacol , vol.142 , pp. 143-150
    • Amacher, D.1    Beck, D.2    Schomaker, S.J.3    Kenny, C.V.4
  • 78
    • 1842855584 scopus 로고    scopus 로고
    • Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes
    • Kocarek T, Dahn MS, Cai H, Strom SC, Mercer-Haines NA. Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. Drug Metab Dispos. 2002;30:1400-5.
    • (2002) Drug Metab Dispos , vol.30 , pp. 1400-1405
    • Kocarek, T.1    Dahn, M.S.2    Cai, H.3    Strom, S.C.4    Mercer-Haines, N.A.5
  • 79
    • 22344439421 scopus 로고    scopus 로고
    • Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor
    • Kobayashi K, Yamanaka Y, Iwazaki N, Nakajo I, Hosokawa M, Negishi M, et al. Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor. Drug Metab Dispos. 2005;33:924-9.
    • (2005) Drug Metab Dispos , vol.33 , pp. 924-929
    • Kobayashi, K.1    Yamanaka, Y.2    Iwazaki, N.3    Nakajo, I.4    Hosokawa, M.5    Negishi, M.6
  • 80
    • 9144234810 scopus 로고    scopus 로고
    • Fan P, Zhang B, Kuroki S, Saku K. Pitavastatin, a potent hydroxymethylglutaryl coenzyme A reductase inhibitor, increases cholesterol 7α-hydroxylase gene expression in HepG2 cells. Circ J. 2004;68:1061-6.
    • Fan P, Zhang B, Kuroki S, Saku K. Pitavastatin, a potent hydroxymethylglutaryl coenzyme A reductase inhibitor, increases cholesterol 7α-hydroxylase gene expression in HepG2 cells. Circ J. 2004;68:1061-6.
  • 81
    • 0037379266 scopus 로고    scopus 로고
    • Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition
    • Sahi J, Black CB, Hamilton GA, Zheng X, Jolley S, Rose KA, et al. Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition. Drug Metab Dispos. 2003;31:439-46.
    • (2003) Drug Metab Dispos , vol.31 , pp. 439-446
    • Sahi, J.1    Black, C.B.2    Hamilton, G.A.3    Zheng, X.4    Jolley, S.5    Rose, K.A.6
  • 82
    • 0021338960 scopus 로고
    • To drink (moderately) or not to drink?
    • Lieber CS. To drink (moderately) or not to drink? N Engl J Med. 1984;310:846-8.
    • (1984) N Engl J Med , vol.310 , pp. 846-848
    • Lieber, C.S.1
  • 84
    • 4344561916 scopus 로고    scopus 로고
    • Adenosine A2A receptor occupancy stimulates expression of proteins involved in reverse cholesterol transport and inhibits foam cell formation in macrophages
    • Reiss AB, Rahman M, Chan ES, Montesinos C, Awadallah NW, Cronstein BN. Adenosine A2A receptor occupancy stimulates expression of proteins involved in reverse cholesterol transport and inhibits foam cell formation in macrophages. J Leucoc Biol. 2004;76:727-34.
    • (2004) J Leucoc Biol , vol.76 , pp. 727-734
    • Reiss, A.B.1    Rahman, M.2    Chan, E.S.3    Montesinos, C.4    Awadallah, N.W.5    Cronstein, B.N.6
  • 87
    • 20144373625 scopus 로고    scopus 로고
    • Fenofibric acid, an active form of fenofibrate increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter AI gene in a liver X receptor-dependent manner
    • Arakawa R, Tamehiro N, Nishimaki-Mogami T, Ueda K, Yokoyama S. Fenofibric acid, an active form of fenofibrate increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter AI gene in a liver X receptor-dependent manner. Arterioscler Thromb Vasc Biol. 2005;25:1193-7.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1193-1197
    • Arakawa, R.1    Tamehiro, N.2    Nishimaki-Mogami, T.3    Ueda, K.4    Yokoyama, S.5
  • 88
    • 0344236149 scopus 로고    scopus 로고
    • Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice
    • Knight BL, Patel DD, Humphreys SM, Wiggins D, Gibbons GF. Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice. J Lipid Res. 2003;44:2049-58.
    • (2003) J Lipid Res , vol.44 , pp. 2049-2058
    • Knight, B.L.1    Patel, D.D.2    Humphreys, S.M.3    Wiggins, D.4    Gibbons, G.F.5
  • 89
    • 1642503920 scopus 로고    scopus 로고
    • Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation
    • Guan J-Z, Tamasava N, Murakami H, Matsui J, Yamato K, Suda T. Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation. Tohoku J Exp Med. 2003;201:251-9.
    • (2003) Tohoku J Exp Med , vol.201 , pp. 251-259
    • Guan, J.-Z.1    Tamasava, N.2    Murakami, H.3    Matsui, J.4    Yamato, K.5    Suda, T.6
  • 90
    • 20444432732 scopus 로고    scopus 로고
    • Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl- CoA reductase inhibition
    • Argmann CA, Edwards JY, Sawyez CG, O'Neil CH, Hegele RA, Pickering JG, et al. Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl- CoA reductase inhibition. J Biol Chem. 2005;280:22212-21.
    • (2005) J Biol Chem , vol.280 , pp. 22212-22221
    • Argmann, C.A.1    Edwards, J.Y.2    Sawyez, C.G.3    O'Neil, C.H.4    Hegele, R.A.5    Pickering, J.G.6
  • 91
    • 5144220807 scopus 로고    scopus 로고
    • Maejima T, Yamazaki H, Aoki T, Tamaki T, Sato F, Kitahara M, et al. Y. Effect of pitavastatin on apolipoprotein A-I production in HepG2 cell. Biochem Biophys Res Commun. 2004;324:835-9.
    • Maejima T, Yamazaki H, Aoki T, Tamaki T, Sato F, Kitahara M, et al. Y. Effect of pitavastatin on apolipoprotein A-I production in HepG2 cell. Biochem Biophys Res Commun. 2004;324:835-9.
  • 92
    • 0034994075 scopus 로고    scopus 로고
    • Statin-induced inhibition of the Rho-signaling pathway activates PPARα and induces HDL apoA-I
    • Martin G, Duez H, Blanquart C, Berezowski V, Poulain P, Fruchart JC, et al. Statin-induced inhibition of the Rho-signaling pathway activates PPARα and induces HDL apoA-I. J Clin Invest. 2001;107:1423-32.
    • (2001) J Clin Invest , vol.107 , pp. 1423-1432
    • Martin, G.1    Duez, H.2    Blanquart, C.3    Berezowski, V.4    Poulain, P.5    Fruchart, J.C.6
  • 93
    • 0032169485 scopus 로고    scopus 로고
    • Human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, Kliewer SA. Human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Invest. 1998;102:1016-23.
    • (1998) J Clin Invest , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    McKee, D.D.2    Watson, M.A.3    Willson, T.M.4    Moore, J.T.5    Kliewer, S.A.6
  • 94
    • 0032793068 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentation and determination factor1/sterol regulatory element binding protein 1: Implications for adipocyte differentiation and metabolism
    • Fajas L, Schoonjans K, Gelman L, Kim JB, Najib J, Martin G, et al. Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentation and determination factor1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism. Mol Cell Biol. 1999;19:5495-503.
    • (1999) Mol Cell Biol , vol.19 , pp. 5495-5503
    • Fajas, L.1    Schoonjans, K.2    Gelman, L.3    Kim, J.B.4    Najib, J.5    Martin, G.6
  • 95
    • 0022222611 scopus 로고
    • Nonpharmacologic and pharmacologic alteration of high-density lipoprotein cholesterol: Therapeutic approaches to prevention of atherosclerosis
    • Glueck CJ. Nonpharmacologic and pharmacologic alteration of high-density lipoprotein cholesterol: therapeutic approaches to prevention of atherosclerosis. Am Heart J. 1985;110:1107-15.
    • (1985) Am Heart J , vol.110 , pp. 1107-1115
    • Glueck, C.J.1
  • 96
    • 0018776515 scopus 로고
    • The effect of cholestyramine on high density lipoprotein metabolism
    • Shepherd J. The effect of cholestyramine on high density lipoprotein metabolism. Atherosclerosis. 1979;33:433-44.
    • (1979) Atherosclerosis , vol.33 , pp. 433-444
    • Shepherd, J.1
  • 97
    • 0028972025 scopus 로고
    • 15-deoxy-Δ 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
    • Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. 15-deoxy-Δ 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell. 1995;83:803-12.
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 98
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor PPARγ
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Wilson TM, Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor PPARγ. J Biol Chem. 1995;270:12953-6.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Wilson, T.M.5    Kliewer, S.A.6
  • 99
    • 21244496784 scopus 로고    scopus 로고
    • Pharmacological augmentation of high-density lipoproteins: Mechanisms of currently available and emerging therapies
    • Myers CD, Kashyap ML. Pharmacological augmentation of high-density lipoproteins: mechanisms of currently available and emerging therapies. Curr Opin Cardiol. 2005;20:307-12.
    • (2005) Curr Opin Cardiol , vol.20 , pp. 307-312
    • Myers, C.D.1    Kashyap, M.L.2
  • 100
    • 0036205326 scopus 로고    scopus 로고
    • Conditional disruption of the peroxisome proliferator-activated receptor γ gene in mice results in lowered expression of ABCA1, ABCG1 and apo E in macrophages and reduced cholesterol efflux
    • Akiyama TE, Sakai S, Lambert G, Nicol CJ, Matsusue K, Pimprale S, et al. Conditional disruption of the peroxisome proliferator-activated receptor γ gene in mice results in lowered expression of ABCA1, ABCG1 and apo E in macrophages and reduced cholesterol efflux. Mol Cell Biol. 2002;22:2607-19.
    • (2002) Mol Cell Biol , vol.22 , pp. 2607-2619
    • Akiyama, T.E.1    Sakai, S.2    Lambert, G.3    Nicol, C.J.4    Matsusue, K.5    Pimprale, S.6
  • 101
    • 0034705071 scopus 로고    scopus 로고
    • CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors
    • Chinetti G, Gbaguidi FG, Griglio S, Mallat Z, Antonucci M, Poulain P, et al. CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors. Circulation. 2000;101:2411-7.
    • (2000) Circulation , vol.101 , pp. 2411-2417
    • Chinetti, G.1    Gbaguidi, F.G.2    Griglio, S.3    Mallat, Z.4    Antonucci, M.5    Poulain, P.6
  • 102
    • 4444337443 scopus 로고    scopus 로고
    • Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signalling in macrophages
    • Szanto A, Benko S, Szatmari I, Balint LB, Furtos I, Rhl R, et al. Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signalling in macrophages. Mol Cell Biol. 2004;24:8154-66.
    • (2004) Mol Cell Biol , vol.24 , pp. 8154-8166
    • Szanto, A.1    Benko, S.2    Szatmari, I.3    Balint, L.B.4    Furtos, I.5    Rhl, R.6
  • 103
    • 13444266129 scopus 로고    scopus 로고
    • Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: A role for RXR and PPARγ ligands
    • Quinn CM, Jessup W, Wong J, Kritharides L, Brown AJ. Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARγ ligands. Biochem J. 2005;385:823-30.
    • (2005) Biochem J , vol.385 , pp. 823-830
    • Quinn, C.M.1    Jessup, W.2    Wong, J.3    Kritharides, L.4    Brown, A.J.5
  • 104
    • 0035987895 scopus 로고    scopus 로고
    • 3A4 induction by drugs: Correlation between a pregnane x receptor receptor gene assay and CYP3A4 expression in human hepatocytes
    • Luo G, Cunningham M, Kim S, Burn T, Lin J, Sinz M, et al. 3A4 induction by drugs: correlation between a pregnane x receptor receptor gene assay and CYP3A4 expression in human hepatocytes. Drug Metab Disp. 2002;30:795-802.
    • (2002) Drug Metab Disp , vol.30 , pp. 795-802
    • Luo, G.1    Cunningham, M.2    Kim, S.3    Burn, T.4    Lin, J.5    Sinz, M.6
  • 105
    • 0034685779 scopus 로고    scopus 로고
    • Orphan nuclear receptors constitutive androstane receptor and Pregnane receptor share xenobiotic and steroid ligands
    • Moore LB, Parks DJ, Jonest SA, Bledsoe RK, Consler TG, Stimmel JB, et al. Orphan nuclear receptors constitutive androstane receptor and Pregnane receptor share xenobiotic and steroid ligands. J Biol Chem. 2000;275:15122-7.
    • (2000) J Biol Chem , vol.275 , pp. 15122-15127
    • Moore, L.B.1    Parks, D.J.2    Jonest, S.A.3    Bledsoe, R.K.4    Consler, T.G.5    Stimmel, J.B.6
  • 109
    • 0014933787 scopus 로고
    • Effects of carbon monoxide exposure on the arterial walls
    • Astrup P, Kjeldsen K, Wanstrup J. Effects of carbon monoxide exposure on the arterial walls. Ann NY Acad Sci. 1970;174:294-300.
    • (1970) Ann NY Acad Sci , vol.174 , pp. 294-300
    • Astrup, P.1    Kjeldsen, K.2    Wanstrup, J.3
  • 110
    • 0038036820 scopus 로고    scopus 로고
    • Comparison of the effects of combined nicotine replacement therapy vs. cigarette smoking in males
    • Haustein KO, Krause J, Haustein H, Rasmussen T, Cort N. Comparison of the effects of combined nicotine replacement therapy vs. cigarette smoking in males. Nicotine Tob Res. 2003;5:195-203.
    • (2003) Nicotine Tob Res , vol.5 , pp. 195-203
    • Haustein, K.O.1    Krause, J.2    Haustein, H.3    Rasmussen, T.4    Cort, N.5
  • 111
    • 0029555396 scopus 로고
    • Influence of worksite tobacco smoke on serum lipoprotein profiles of female nonsmokers
    • Moffatt RJ, Stamford BA, Biggerstaff KD. Influence of worksite tobacco smoke on serum lipoprotein profiles of female nonsmokers. Metabolism. 1995;44:1536-9.
    • (1995) Metabolism , vol.44 , pp. 1536-1539
    • Moffatt, R.J.1    Stamford, B.A.2    Biggerstaff, K.D.3
  • 112
    • 13844256197 scopus 로고    scopus 로고
    • Heterogeneity of cardiovascular risk among smokers is related to degree of carbon monoxide exposure
    • Hedblad B, Ögren M, Engström G, Wollmer P, Janzon L. Heterogeneity of cardiovascular risk among smokers is related to degree of carbon monoxide exposure. Atherosclerosis. 2005;179:177-83.
    • (2005) Atherosclerosis , vol.179 , pp. 177-183
    • Hedblad, B.1    Ögren, M.2    Engström, G.3    Wollmer, P.4    Janzon, L.5
  • 113
    • 9144222145 scopus 로고    scopus 로고
    • Interferon-γ impedes reverse cholesterol transport and promotes foam cell transformation in TPH-1 human monocytes/macrophages
    • Reiss AB, Patel CA, Rahman MM, Chan ESL, Hasneen K, Montesinos MM, et al. Interferon-γ impedes reverse cholesterol transport and promotes foam cell transformation in TPH-1 human monocytes/macrophages. Med Sci Monit. 2004;10:BR420-5.
    • (2004) Med Sci Monit , vol.10
    • Reiss, A.B.1    Patel, C.A.2    Rahman, M.M.3    Chan, E.S.L.4    Hasneen, K.5    Montesinos, M.M.6
  • 114
    • 0026043811 scopus 로고
    • Cytochrome isoforms. Regulation during infection, inflammation and by cytokines
    • Williams JF. Cytochrome isoforms. Regulation during infection, inflammation and by cytokines. J Fla Med Assoc. 1991;78:517-9.
    • (1991) J Fla Med Assoc , vol.78 , pp. 517-519
    • Williams, J.F.1
  • 115
    • 0034080596 scopus 로고    scopus 로고
    • Interferon-γ induces down-regulation of Tangier disease gene (ATP-binding cassette transporter 1) in macrophage derived foam cells
    • Panousis VG, Zuckerman SH. Interferon-γ induces down-regulation of Tangier disease gene (ATP-binding cassette transporter 1) in macrophage derived foam cells. Arterioscler Thromb Vasc Biol. 2000;20:1565-71.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1565-1571
    • Panousis, V.G.1    Zuckerman, S.H.2
  • 117
    • 85047684249 scopus 로고    scopus 로고
    • Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
    • Pullinger CR, Eng C, Salen G, Shefer S, Barra AK, Erickson SK, et al. Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. J Clin Invest. 2002;110:109-17.
    • (2002) J Clin Invest , vol.110 , pp. 109-117
    • Pullinger, C.R.1    Eng, C.2    Salen, G.3    Shefer, S.4    Barra, A.K.5    Erickson, S.K.6
  • 118
    • 0342506477 scopus 로고    scopus 로고
    • Prevention of the angiographic progression of coronary vein-graft atherosclerosis by gemfibrozil after coronary by-pass surgery in men with low levels of HDL cholesterol
    • Frick MH, Syvänne M, Nieminen MS, Kauma H, Majahalme S, Virtanen V, et al. Prevention of the angiographic progression of coronary vein-graft atherosclerosis by gemfibrozil after coronary by-pass surgery in men with low levels of HDL cholesterol. Circulation. 1997;96:2137-43.
    • (1997) Circulation , vol.96 , pp. 2137-2143
    • Frick, M.H.1    Syvänne, M.2    Nieminen, M.S.3    Kauma, H.4    Majahalme, S.5    Virtanen, V.6
  • 119
    • 0029982038 scopus 로고    scopus 로고
    • Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients
    • Ericsson CG, de Faire U, Grip L, Svane B, Hamsten A, Nilsson J. Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients. Lancet. 1996;347:849-53.
    • (1996) Lancet , vol.347 , pp. 849-853
    • Ericsson, C.G.1    de Faire, U.2    Grip, L.3    Svane, B.4    Hamsten, A.5    Nilsson, J.6
  • 120
    • 0035941990 scopus 로고    scopus 로고
    • Effect of fenofibrate on progression of coronary artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study, a randomised study
    • Effect of fenofibrate on progression of coronary artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet. 2001;357:905-10.
    • (2001) Lancet , vol.357 , pp. 905-910
  • 121
    • 0027981582 scopus 로고
    • Effect of simvastatin on coronary atheroma. The Multicentre Anti-Atheroma Study (MAAS)
    • Effect of simvastatin on coronary atheroma. The Multicentre Anti-Atheroma Study (MAAS). Lancet. 1994;344:633-8.
    • (1994) Lancet , vol.344 , pp. 633-638
  • 122
    • 0027488722 scopus 로고
    • Coronary angiographic changes with lovastatin therapy; The Monitored Atherosclerosis Regression Study (MARS)
    • and the MARS Research Group
    • Blankenhorn DH, Azen SP, Kramsch DM, Mack WJ, Cashin-Hemphill L, Hodis HN, et al., and the MARS Research Group. Coronary angiographic changes with lovastatin therapy; The Monitored Atherosclerosis Regression Study (MARS). Ann Intern Med. 1993;119:969-76.
    • (1993) Ann Intern Med , vol.119 , pp. 969-976
    • Blankenhorn, D.H.1    Azen, S.P.2    Kramsch, D.M.3    Mack, W.J.4    Cashin-Hemphill, L.5    Hodis, H.N.6
  • 124
    • 18844366928 scopus 로고    scopus 로고
    • Pioglitazone decreases carotid intima-media thickness independently of glycemic control in patients with type 2 diabetes mellitus. Results from a controlled randomized study
    • Langenfeld MR, Forst T, Hohberg C, Kann P, Lubben G, Konrad T, et al. Pioglitazone decreases carotid intima-media thickness independently of glycemic control in patients with type 2 diabetes mellitus. Results from a controlled randomized study. Circulation. 2005;111:2525-31.
    • (2005) Circulation , vol.111 , pp. 2525-2531
    • Langenfeld, M.R.1    Forst, T.2    Hohberg, C.3    Kann, P.4    Lubben, G.5    Konrad, T.6
  • 125
    • 0011428103 scopus 로고
    • Influence of some factors on development of experimental cholesterol atherosclerosis
    • Myasnikov AL. Influence of some factors on development of experimental cholesterol atherosclerosis. Circulation. 1958;17:99-113.
    • (1958) Circulation , vol.17 , pp. 99-113
    • Myasnikov, A.L.1
  • 126
    • 0014802061 scopus 로고
    • Effect of phenobarbital and chlorcyclizine on the development of atheromatosis in the cholesterol-fed rabbit
    • Salvador RA, Atkins C, Haber S, Kozma C, Conney AH. Effect of phenobarbital and chlorcyclizine on the development of atheromatosis in the cholesterol-fed rabbit. Biochem Pharmacol. 1970;19:1975-81.
    • (1970) Biochem Pharmacol , vol.19 , pp. 1975-1981
    • Salvador, R.A.1    Atkins, C.2    Haber, S.3    Kozma, C.4    Conney, A.H.5
  • 127
    • 0031971817 scopus 로고    scopus 로고
    • Alcohol consumption and atherosclerosis: What is the relation. Prospective results from the Bruneck study
    • Kiehl S, Willeit J, Rungger G, Egger G, Oberhollenzer F, Bonora E, et al. Alcohol consumption and atherosclerosis: What is the relation. Prospective results from the Bruneck study. Stroke. 1998;29:900-7.
    • (1998) Stroke , vol.29 , pp. 900-907
    • Kiehl, S.1    Willeit, J.2    Rungger, G.3    Egger, G.4    Oberhollenzer, F.5    Bonora, E.6
  • 128
    • 33745939988 scopus 로고    scopus 로고
    • Coronary atherosclerosis and alcohol consumption. Angiographic and mortality data
    • Femia R, Natali A, L'Abbate A, Ferrannini E. Coronary atherosclerosis and alcohol consumption. Angiographic and mortality data. Arterioscler Thromb Vasc Biol. 2006;26:1607-12.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1607-1612
    • Femia, R.1    Natali, A.2    L'Abbate, A.3    Ferrannini, E.4
  • 129
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia
    • Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, et al. Helsinki Heart Study: primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia. New Engl J Med. 1987;317:1237-45.
    • (1987) New Engl J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3    Heinonen, O.P.4    Heinsalmi, P.5    Helo, P.6
  • 130
    • 33645729392 scopus 로고    scopus 로고
    • Gemfibrozil in the treatment of dyslipidemia. An 18-year follow-up of the Helsinki Heart Study
    • Tenkanen L, Mänttäri M, Kovanen PT, Virkkunen H, Manninen V. Gemfibrozil in the treatment of dyslipidemia. An 18-year follow-up of the Helsinki Heart Study. Arch Intern Med. 2006;166:743-8.
    • (2006) Arch Intern Med , vol.166 , pp. 743-748
    • Tenkanen, L.1    Mänttäri, M.2    Kovanen, P.T.3    Virkkunen, H.4    Manninen, V.5
  • 131
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9759 people with type 2 diabetes mellitus (the FIELD Study): Randomised controlled trial
    • Keech A, Simes RJ, Barter J, Best J, Scott R, Taskinen MR, et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9759 people with type 2 diabetes mellitus (the FIELD Study): randomised controlled trial. Lancet. 2005;366:1849-61.
    • (2005) Lancet , vol.366 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, J.3    Best, J.4    Scott, R.5    Taskinen, M.R.6
  • 132
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383-9.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 133
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 134
    • 2342468034 scopus 로고    scopus 로고
    • Meta-analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes
    • Cheung BMY, Lauder IJ, Lau C-P, Kumana C. Meta-analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes. Br J Clin Pharmacol. 2004;57:640-51.
    • (2004) Br J Clin Pharmacol , vol.57 , pp. 640-651
    • Cheung, B.M.Y.1    Lauder, I.J.2    Lau, C.-P.3    Kumana, C.4
  • 135
    • 26244432388 scopus 로고    scopus 로고
    • Cholesterol Treatment Trialists' (CTT) Collaborators. Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins
    • Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C, et al., Cholesterol Treatment Trialists' (CTT) Collaborators. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins. Lancet. 2005;366:1267-78.
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3    Blackwell, L.4    Buck, G.5    Pollicino, C.6
  • 136
    • 0021350001 scopus 로고
    • results. I. Reduction in the incidence of coronary heart disease
    • The Lipid Research Clinics Coronary Primary Prevention Trial
    • The Lipid Research Clinics Coronary Primary Prevention Trial: results. I. Reduction in the incidence of coronary heart disease. JAMA. 1984;251:351-64.
    • (1984) JAMA , vol.251 , pp. 351-364
  • 137
    • 26244453309 scopus 로고    scopus 로고
    • Secondary prevention of macrovascular events in patients with type 2 diabetes in the Proactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomised controlled trial
    • Dormandy JA, Charbonnel B, Eckland DAJ, Erdmann E, Massi-Benedetti M, Moules IK, et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the Proactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet. 2005;366:1279-89.
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.A.J.3    Erdmann, E.4    Massi-Benedetti, M.5    Moules, I.K.6
  • 138
    • 0028905623 scopus 로고
    • Alcohol and mortality: A review
    • Poikolainen K. Alcohol and mortality: a review. J Clin Epidemiol. 1995;48:455-65.
    • (1995) J Clin Epidemiol , vol.48 , pp. 455-465
    • Poikolainen, K.1
  • 139
    • 0021833979 scopus 로고
    • Plasma HDL cholesterol and blood glucose in non-insulin-dependent diabetics related to liver lipids and microsomal enzyme activity
    • Luoma PV, Savolainen MJ, Sotaniemi EA, Arranto AJ, Pelkonen RO. Plasma HDL cholesterol and blood glucose in non-insulin-dependent diabetics related to liver lipids and microsomal enzyme activity. Acta Med Scand. 1985;217:473-9.
    • (1985) Acta Med Scand , vol.217 , pp. 473-479
    • Luoma, P.V.1    Savolainen, M.J.2    Sotaniemi, E.A.3    Arranto, A.J.4    Pelkonen, R.O.5
  • 140
    • 0025312732 scopus 로고
    • High-density lipoprotein subfractions, apolipoproteins and antipyrine clearance in normal subjects
    • Luoma PV, Rautio A, Stengård J, Sotaniemi EA, Marniemi J. High-density lipoprotein subfractions, apolipoproteins and antipyrine clearance in normal subjects. Eur J Clin Pharmacol. 1990;38:625-7.
    • (1990) Eur J Clin Pharmacol , vol.38 , pp. 625-627
    • Luoma, P.V.1    Rautio, A.2    Stengård, J.3    Sotaniemi, E.A.4    Marniemi, J.5
  • 141
    • 0016695850 scopus 로고
    • Hepatic drug-oxidizing enzyme systems and urinary D-glucaric acid excretion in patients with congestive heart failure
    • Tokola O, Pelkonen O, Karki NT, Luoma P. Hepatic drug-oxidizing enzyme systems and urinary D-glucaric acid excretion in patients with congestive heart failure. Br J Clin Pharmacol. 1975;2:429-36.
    • (1975) Br J Clin Pharmacol , vol.2 , pp. 429-436
    • Tokola, O.1    Pelkonen, O.2    Karki, N.T.3    Luoma, P.4
  • 142
    • 0020362982 scopus 로고
    • Relationship between plasma high-density lipoprotein cholesterol and anticonvulsant levels in epileptics
    • Luoma PV, Myllylä VV, Hokkanen E. Relationship between plasma high-density lipoprotein cholesterol and anticonvulsant levels in epileptics. J Cardiovasc Pharmacol. 1982;4:1024-7.
    • (1982) J Cardiovasc Pharmacol , vol.4 , pp. 1024-1027
    • Luoma, P.V.1    Myllylä, V.V.2    Hokkanen, E.3
  • 143
    • 0019787889 scopus 로고
    • The relationship between alcohol consumption, liver enzymes and high-density lipoprotein cholesterol
    • LaPorte R, Valvo-Gerard L, Kuller L, Wanju R, Bates M, Cresanta J, et al. The relationship between alcohol consumption, liver enzymes and high-density lipoprotein cholesterol. Circulation. 1981;64 suppl III: 67-72.
    • (1981) Circulation , vol.64 , Issue.SUPPL. III , pp. 67-72
    • LaPorte, R.1    Valvo-Gerard, L.2    Kuller, L.3    Wanju, R.4    Bates, M.5    Cresanta, J.6
  • 144
    • 0024334726 scopus 로고
    • Factors associated with high density lipoprotein cholesterol in a population with high high density lipoprotein cholesterol levels
    • Steyn K, Fourie J, Benade AJ, Roussow JE, Langenhoven ML, Joubert G, et al. Factors associated with high density lipoprotein cholesterol in a population with high high density lipoprotein cholesterol levels. Arteriosclerosis. 1989;9:390-7.
    • (1989) Arteriosclerosis , vol.9 , pp. 390-397
    • Steyn, K.1    Fourie, J.2    Benade, A.J.3    Roussow, J.E.4    Langenhoven, M.L.5    Joubert, G.6
  • 145
    • 0021333707 scopus 로고
    • Decreases in serum high-density-lipoprotein cholesterol and total cholesterol resulting from naturally produced recombinant DNA-derived leucocyte interferon
    • Dixon RM, Borden EC, Keim NL, Anderson S, Spennetta TL, Tormey DC, et al. Decreases in serum high-density-lipoprotein cholesterol and total cholesterol resulting from naturally produced recombinant DNA-derived leucocyte interferon. Metabolism. 1984;33:400-4.
    • (1984) Metabolism , vol.33 , pp. 400-404
    • Dixon, R.M.1    Borden, E.C.2    Keim, N.L.3    Anderson, S.4    Spennetta, T.L.5    Tormey, D.C.6
  • 147
    • 0028913935 scopus 로고
    • Hepatic microsomal induction profile of carbamic acid [[2,6-bis(1-methylethyl) phenoxy] sulfonyl]-2,6-bis(1-methylethyl) phenyl ester, monosodium salt (PD138142-15), a novel lipid regulating agent
    • Robertson RG, Krause BR, Welty DF, Wolfgang GHI, Grazian MJ, Pilcher GD, et al. Hepatic microsomal induction profile of carbamic acid [[2,6-bis(1-methylethyl) phenoxy] sulfonyl]-2,6-bis(1-methylethyl) phenyl ester, monosodium salt (PD138142-15), a novel lipid regulating agent. Biochem Pharmacol. 1995;49:799-808.
    • (1995) Biochem Pharmacol , vol.49 , pp. 799-808
    • Robertson, R.G.1    Krause, B.R.2    Welty, D.F.3    Wolfgang, G.H.I.4    Grazian, M.J.5    Pilcher, G.D.6
  • 148
    • 22344444593 scopus 로고    scopus 로고
    • The nuclear receptor superfamily: A rosette stone for physiology
    • Evans RM. The nuclear receptor superfamily: a rosette stone for physiology. Mol Endocrinol. 2005;19:1429-38.
    • (2005) Mol Endocrinol , vol.19 , pp. 1429-1438
    • Evans, R.M.1
  • 149
    • 0019123306 scopus 로고
    • Low high-density lipoprotein and reduced antipyrine metabolism in members of a family with polycystic liver disease
    • Luoma PV, Sotaniemi EA, Ehnholm C. Low high-density lipoprotein and reduced antipyrine metabolism in members of a family with polycystic liver disease. Scand J Gastroenterol. 1980;15:869-73.
    • (1980) Scand J Gastroenterol , vol.15 , pp. 869-873
    • Luoma, P.V.1    Sotaniemi, E.A.2    Ehnholm, C.3
  • 150
    • 0021930594 scopus 로고
    • Serum low density and high density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes
    • Luoma PV, Sotaniemi EA, Pelkonen RO, Pirttiaho HI. Serum low density and high density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes. Eur J Clin Pharmacol. 1985;28:615-8.
    • (1985) Eur J Clin Pharmacol , vol.28 , pp. 615-618
    • Luoma, P.V.1    Sotaniemi, E.A.2    Pelkonen, R.O.3    Pirttiaho, H.I.4
  • 151
    • 0343729334 scopus 로고    scopus 로고
    • Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface
    • Bretillon L, Lütjohann D, Ståhle L, Widhe T, Bindl L, Eggertsen G, et al. Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface. J Lipid Res. 2000;41:840-5.
    • (2000) J Lipid Res , vol.41 , pp. 840-845
    • Bretillon, L.1    Lütjohann, D.2    Ståhle, L.3    Widhe, T.4    Bindl, L.5    Eggertsen, G.6
  • 152
    • 26944471737 scopus 로고    scopus 로고
    • Lehrke M, Lebherz C, Millington SC, Guan HP, Millar J, Rader DJ, et al. Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRα. Cell Metab. 2005;1:297-308.
    • Lehrke M, Lebherz C, Millington SC, Guan HP, Millar J, Rader DJ, et al. Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRα. Cell Metab. 2005;1:297-308.
  • 154
    • 0037432165 scopus 로고    scopus 로고
    • T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice
    • Terasaka N, Hiroshima A, Koieyama T, Ubukata N, Morikawa Y, Nakai D, et al. T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice. FEBS Lett. 2003;536:6-11.
    • (2003) FEBS Lett , vol.536 , pp. 6-11
    • Terasaka, N.1    Hiroshima, A.2    Koieyama, T.3    Ubukata, N.4    Morikawa, Y.5    Nakai, D.6
  • 155
    • 0037432158 scopus 로고    scopus 로고
    • Pharmacological evidence for a role of liver X receptors in atheroprotection
    • Kovanen PT, Pentikäinen MO. Pharmacological evidence for a role of liver X receptors in atheroprotection. FEBS Lett. 2003;536:3-5.
    • (2003) FEBS Lett , vol.536 , pp. 3-5
    • Kovanen, P.T.1    Pentikäinen, M.O.2
  • 157
    • 33644865172 scopus 로고    scopus 로고
    • Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo
    • Naik SU, Wang X, Da Silva JS, Jaye M, Macphee CH, Reilly MR, et al. Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo. Circulation. 2006;113:90-7.
    • (2006) Circulation , vol.113 , pp. 90-97
    • Naik, S.U.1    Wang, X.2    Da Silva, J.S.3    Jaye, M.4    Macphee, C.H.5    Reilly, M.R.6


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