Oxysterol-induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC- and PKA-dependent pathway

Journal of Cellular Biochemistry

Volumn 100, Issue 5, 2007, Pages 1131-1145

  Richardson, Jennifer A ^a   Amantea, Christopher M ^a   Kianmahd, Benjamin ^a   Tetradis, Sotirios ^b   Lieberman, Jay R ^a   Hahn, Theodore J ^c   Parhami, Farhad ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UCLA SCHOOL OF DENTISTRY   (United States)

^c VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

Marrow stromal cells; Osteoblastic differentiation; Oxysterols; PKA; PKC; Runx2

Indexed keywords

ALKALINE PHOSPHATASE; BISINDOLYLMALEIMIDE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 14; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OSTEOCALCIN; OSTEOGENIC PROTEIN 1; OXYSTEROL; PROTEIN KINASE C; ROTTLERIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; C3H MOUSE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME MECHANISM; FIBROBLAST; MESENCHYME CELL; MOUSE; NONHUMAN; OSTEOBLAST; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM;

ALKALINE PHOSPHATASE; ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CYCLIC AMP-DEPENDENT PROTEIN KINASES; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C3H; OSTEOBLASTS; PLURIPOTENT STEM CELLS; PROTEIN KINASE C; SIGNAL TRANSDUCTION; STEROLS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 33947573706     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21112     Document Type: Article

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