Enzymatic Reduction of Oxysterols Impairs LXR Signaling in Cultured Cells and the Livers of Mice

Cell Metabolism

Volumn 5, Issue 1, 2007, Pages 73-79

  Chen, Wenling ^a   Chen, Guoxen ^a   Head, Daphne L ^a   Mangelsdorf, David J ^a,b   Russell, David W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

HUMDISEASE

Indexed keywords

25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; CHOLESTEROL; CHOLESTEROL DERIVATIVE; LIGAND; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; OXYSTEROL; SULFOTRANSFERASE;

ADENOVIRUS VECTOR; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIETARY INTAKE; ENZYME DEGRADATION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LIVER; MALE; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CELLS, CULTURED; CRICETINAE; DNA-BINDING PROTEINS; HEPATOCYTES; HUMANS; HYDROXYCHOLESTEROLS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SULFOTRANSFERASES; TRANSFECTION;

ADENOVIRIDAE; MAMMALIA;

EID: 33845587711     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2006.11.012     Document Type: Article

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