-
1
-
-
0023243055
-
Cholesterol autoxidation
-
Smith, L. L. 1987. Cholesterol autoxidation. Chem. Phys. Lipids. 44: 87-125.
-
(1987)
Chem. Phys. Lipids
, vol.44
, pp. 87-125
-
-
Smith, L.L.1
-
2
-
-
0017205073
-
Angiotoxicity and atherosclerosis due to contaminants of USP-grade cholesterol
-
Imai, H., N. T. Werthessen, C. B. Taylor, and K. T. Lee. 1976. Angiotoxicity and atherosclerosis due to contaminants of USP-grade cholesterol. Arch. Pathol. Lab. Med. 100: 565-572.
-
(1976)
Arch. Pathol. Lab. Med.
, vol.100
, pp. 565-572
-
-
Imai, H.1
Werthessen, N.T.2
Taylor, C.B.3
Lee, K.T.4
-
3
-
-
0024995969
-
26-Hydroxycholesterol: Synthesis, metabolism and biologic activities
-
Javitt, N. B. 1990. 26-Hydroxycholesterol: synthesis, metabolism and biologic activities. J. Lipid Res. 31: 1527-1533.
-
(1990)
J. Lipid Res.
, vol.31
, pp. 1527-1533
-
-
Javitt, N.B.1
-
4
-
-
0018330812
-
26-Hydroxylation of C27-steroids by soluble liver mitochondrial cytochrome P-450
-
Pederson, J. L., I. Björkhem and J. Gustaffson. 1979. 26-Hydroxylation of C27-steroids by soluble liver mitochondrial cytochrome P-450. J. Biol. Chem. 254: 6464-6469.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 6464-6469
-
-
Pederson, J.L.1
Björkhem, I.2
Gustaffson, J.3
-
5
-
-
0025831073
-
Effect of inserted oxysterols on phospholipid packing in normal and sickle red blood cell membranes
-
Szotek, R., O. Kucuk, L. J. Lis, D. Tracy, R. Mata, T. Dey, J. W. Kauffman, S. Yachnin, and M. P. Westerman. 1991. Effect of inserted oxysterols on phospholipid packing in normal and sickle red blood cell membranes. Biochem. Biophys. Res. Commun. 180: 730-734.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.180
, pp. 730-734
-
-
Szotek, R.1
Kucuk, O.2
Lis, L.J.3
Tracy, D.4
Mata, R.5
Dey, T.6
Kauffman, J.W.7
Yachnin, S.8
Westerman, M.P.9
-
6
-
-
0019418314
-
Diminished osmotic fragility of human erythrocytes following the membrane insertion of oxygenated sterol compounds
-
Theuneissen, J. J., J. R. Kanofsky, R. B. Gunn, and S. Yachnin. 1981. Diminished osmotic fragility of human erythrocytes following the membrane insertion of oxygenated sterol compounds. Blood. 58: 317-325.
-
(1981)
Blood
, vol.58
, pp. 317-325
-
-
Theuneissen, J.J.1
Kanofsky, J.R.2
Gunn, R.B.3
Yachnin, S.4
-
7
-
-
0016745486
-
Regulation of sterol synthesis in cultured cells by oxygenated derivatives of cholesterol
-
Kandutsch, A. A., and H. W. Chen. 1975. Regulation of sterol synthesis in cultured cells by oxygenated derivatives of cholesterol. J. Cell Physiol. 85: 415-424.
-
(1975)
J. Cell Physiol.
, vol.85
, pp. 415-424
-
-
Kandutsch, A.A.1
Chen, H.W.2
-
8
-
-
0026248941
-
Biological activities of oxygenated sterols: Physiological and pathological implications
-
Hwang, P. L. 1991. Biological activities of oxygenated sterols: physiological and pathological implications. Bioessays. 13: 583-589.
-
(1991)
Bioessays
, vol.13
, pp. 583-589
-
-
Hwang, P.L.1
-
9
-
-
0344485416
-
Effects of cholesterol oxidation derivatives on cholesterol esterifying and cholesteryl ester hydrolytic enzyme activity of cultured rabbit smooth muscle cells
-
Morin, R. J., and S. K. Peng. 1992. Effects of cholesterol oxidation derivatives on cholesterol esterifying and cholesteryl ester hydrolytic enzyme activity of cultured rabbit smooth muscle cells. Lipids. 27: 478-480.
-
(1992)
Lipids
, vol.27
, pp. 478-480
-
-
Morin, R.J.1
Peng, S.K.2
-
10
-
-
0026668329
-
Effect of 25-hydroxycholesterol on cholesterol ester formation in CaCo-2 cells
-
Kusuhara, H., O. Shimada, and J. Inui. 1992. Effect of 25-hydroxycholesterol on cholesterol ester formation in CaCo-2 cells. Lipids. 27: 478-480.
-
(1992)
Lipids
, vol.27
, pp. 478-480
-
-
Kusuhara, H.1
Shimada, O.2
Inui, J.3
-
11
-
-
0018741258
-
Spontaneously occurring angiotoxic derivatives of cholesterol
-
Taylor, C. B., S. K. Peng, N. T. Werthessen, P. Tham, and K. T. Lee. 1979. Spontaneously occurring angiotoxic derivatives of cholesterol. Am. J. Clin. Nutr. 32: 40-57.
-
(1979)
Am. J. Clin. Nutr.
, vol.32
, pp. 40-57
-
-
Taylor, C.B.1
Peng, S.K.2
Werthessen, N.T.3
Tham, P.4
Lee, K.T.5
-
12
-
-
0028227192
-
Cytotoxicity of oxidized LDL to porcine smooth muscle cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol
-
Hughes, H., B. Matthews, M. L. Lenz, and J. L. Guyton. 1994. Cytotoxicity of oxidized LDL to porcine smooth muscle cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol. Arterioscler. Thromb. 14: 1177-1185.
-
(1994)
Arterioscler. Thromb.
, vol.14
, pp. 1177-1185
-
-
Hughes, H.1
Matthews, B.2
Lenz, M.L.3
Guyton, J.L.4
-
13
-
-
0028218536
-
Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-)
-
Hodis, H. N., D. M. Kramsch, P. Avogaro, G. Bittolo-Bon, G. Cazzolato, J. Hwang, H. Peterson, and A. Sevanian. 1994. Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-). J. Lipid Res. 35: 669-677.
-
(1994)
J. Lipid Res.
, vol.35
, pp. 669-677
-
-
Hodis, H.N.1
Kramsch, D.M.2
Avogaro, P.3
Bittolo-Bon, G.4
Cazzolato, G.5
Hwang, J.6
Peterson, H.7
Sevanian, A.8
-
14
-
-
0022974733
-
Occurrence of lipid oxidation products of foods
-
Addis, P. B. 1986. Occurrence of lipid oxidation products of foods. Food Chem. Toxicol. 24: 1021-1031.
-
(1986)
Food Chem. Toxicol.
, vol.24
, pp. 1021-1031
-
-
Addis, P.B.1
-
15
-
-
0023727786
-
Quantification of oxysterols in Dutch foods: Egg products and mixed diets
-
van de Bovenkamp, P., T. G. Kosmeijer-Schuil, and M. B. Katan. 1988. Quantification of oxysterols in Dutch foods: egg products and mixed diets. Lipids. 23: 1079-1085.
-
(1988)
Lipids
, vol.23
, pp. 1079-1085
-
-
Van De Bovenkamp, P.1
Kosmeijer-Schuil, T.G.2
Katan, M.B.3
-
16
-
-
0001091025
-
Effects of processing stage and storage conditions on cholesterol oxidation products in butter and cheddar cheese
-
Sander, B. D., D. E. Smith, and P. B. Addis. 1988. Effects of processing stage and storage conditions on cholesterol oxidation products in butter and cheddar cheese. J. Dairy Sci. 71: 3173-3178.
-
(1988)
J. Dairy Sci.
, vol.71
, pp. 3173-3178
-
-
Sander, B.D.1
Smith, D.E.2
Addis, P.B.3
-
17
-
-
0024988421
-
Simultaneous quantification of several cholesterol autoxidation and monohydroxylation products by isotope-dilution mass spectrometry
-
Breuer, O., and I. Björkhem. 1990. Simultaneous quantification of several cholesterol autoxidation and monohydroxylation products by isotope-dilution mass spectrometry. Steroids. 55: 185-192.
-
(1990)
Steroids
, vol.55
, pp. 185-192
-
-
Breuer, O.1
Björkhem, I.2
-
18
-
-
84985222654
-
Plasma cholesterol oxidation products (oxysterols) in human subjects fed a meal rich in oxysterols
-
Emanuel, H. A., C. A. Hassel, P. B. Addis, S. D. Bergmann, and J. H. Zavoral. 1991. Plasma cholesterol oxidation products (oxysterols) in human subjects fed a meal rich in oxysterols. J. Food Sci. 56: 843-847.
-
(1991)
J. Food Sci.
, vol.56
, pp. 843-847
-
-
Emanuel, H.A.1
Hassel, C.A.2
Addis, P.B.3
Bergmann, S.D.4
Zavoral, J.H.5
-
19
-
-
0028566165
-
In vivo formation of 25-hydroxycholesterol from endogenous cholesterol after a single meal, dietary cholesterol challenge
-
Johnson, K. A., C. Morrow, G. D. Knight, and T. J. Scallen. 1994. In vivo formation of 25-hydroxycholesterol from endogenous cholesterol after a single meal, dietary cholesterol challenge. J. Lipid Res. 35: 2241-2253.
-
(1994)
J. Lipid Res.
, vol.35
, pp. 2241-2253
-
-
Johnson, K.A.1
Morrow, C.2
Knight, G.D.3
Scallen, T.J.4
-
20
-
-
0025776831
-
Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: Further evidence for the role of cholesterol oxidation in atherosclerosis
-
Hodis, H. N., D. W. Crawford, and A. Sevanian. 1991. Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: further evidence for the role of cholesterol oxidation in atherosclerosis. Atherosclerosis. 89: 117-129.
-
(1991)
Atherosclerosis
, vol.89
, pp. 117-129
-
-
Hodis, H.N.1
Crawford, D.W.2
Sevanian, A.3
-
21
-
-
0026733425
-
Probucol reduces plasma and aortic wall oxysterol levels in cholesterol-fed rabbits independendy of its plasma cholesterol lowering effect
-
Hodis, H. N., A. Chauban, S. Hashimoto, D. W. Crawford, and A. Sevanian. 1992. Probucol reduces plasma and aortic wall oxysterol levels in cholesterol-fed rabbits independendy of its plasma cholesterol lowering effect. Atherosclerosis. 96: 125-134.
-
(1992)
Atherosclerosis
, vol.96
, pp. 125-134
-
-
Hodis, H.N.1
Chauban, A.2
Hashimoto, S.3
Crawford, D.W.4
Sevanian, A.5
-
22
-
-
0022341712
-
Identification of regulatory oxysterols, 24(S), 25-epoxycholesterol and 25-hydroxycholesterol in cultured fibroblasts
-
Saucier, S. E., A. A. Kandutsch, F. R. Taylor, T. A. Spencer, S. Phirwa, and A. K. Gayen. 1985. Identification of regulatory oxysterols, 24(S), 25-epoxycholesterol and 25-hydroxycholesterol in cultured fibroblasts. J. Biol. Chem. 260: 14571-14579.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 14571-14579
-
-
Saucier, S.E.1
Kandutsch, A.A.2
Taylor, F.R.3
Spencer, T.A.4
Phirwa, S.5
Gayen, A.K.6
-
23
-
-
0028068796
-
Atherosclerosis and 27-hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages
-
Björkhem, I., O. Andersson, U. Diczfalusy, B. Sevastik, R. J. Xiu, C. Duan, and E. Lund. 1994. Atherosclerosis and 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages. Proc. Natl. Acad. Sci. USA. 91: 8592-8596.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8592-8596
-
-
Björkhem, I.1
Andersson, O.2
Diczfalusy, U.3
Sevastik, B.4
Xiu, R.J.5
Duan, C.6
Lund, E.7
-
24
-
-
0020637106
-
Risk factors and atherosclerotic lesions. A review of autopsy studies
-
Solberg, L. A., and J. P. Strong. 1983. Risk factors and atherosclerotic lesions. A review of autopsy studies. Arteriosclerosis. 3: 187-198.
-
(1983)
Arteriosclerosis
, vol.3
, pp. 187-198
-
-
Solberg, L.A.1
Strong, J.P.2
-
25
-
-
0028783931
-
Distribution of oxysterols in human serum: Characterization of 25-hydroxycholesterol association with serum albumin
-
Lin, C. Y., and D. W. Morel. 1995. Distribution of oxysterols in human serum: characterization of 25-hydroxycholesterol association with serum albumin. J. Nutr. Biochem. 6: 618-625.
-
(1995)
J. Nutr. Biochem.
, vol.6
, pp. 618-625
-
-
Lin, C.Y.1
Morel, D.W.2
-
26
-
-
0028909854
-
Inhibition of cellular cholesterol efflux by 25-hydroxycholesterol
-
Kilsdonk, E. P. C., D. W. Morel, W. J. Johnson, and G. H. Rothblat. 1995. Inhibition of cellular cholesterol efflux by 25-hydroxycholesterol. J. Lipid Res. 36: 505-516.
-
(1995)
J. Lipid Res.
, vol.36
, pp. 505-516
-
-
Kilsdonk, E.P.C.1
Morel, D.W.2
Johnson, W.J.3
Rothblat, G.H.4
-
27
-
-
0028964742
-
Cell toxicity induced by inhibition of acetyl CoA:cholesterol acyltransferase and accumulation of unesterified cholesterol
-
Warner, G. J., G. Stoudt, M. Bamberger, W. J. Johnson, and G. H. Rothblat. 1995. Cell toxicity induced by inhibition of acetyl CoA:cholesterol acyltransferase and accumulation of unesterified cholesterol. J. Biol. Chem. 270: 5772-5778.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5772-5778
-
-
Warner, G.J.1
Stoudt, G.2
Bamberger, M.3
Johnson, W.J.4
Rothblat, G.H.5
-
28
-
-
0021320894
-
Selective inhibition of acyl coenzyme A:cholesterol acyltransferase by compound 58-035
-
Ross, A. C., K. J. Go, J. G. Heider, and G. H. Rothblat. 1984. Selective inhibition of acyl coenzyme A:cholesterol acyltransferase by compound 58-035. J. Biol. Chem. 259: 815-819.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 815-819
-
-
Ross, A.C.1
Go, K.J.2
Heider, J.G.3
Rothblat, G.H.4
-
29
-
-
0023151506
-
p-Nitrophenyl and cholesteryl N-alkyl carbamates as inhibitors of cholesterol esterase
-
Hosie, L., L. D. Sutton, and D. M. Quinn. 1987. p-Nitrophenyl and cholesteryl N-alkyl carbamates as inhibitors of cholesterol esterase. J. Biol. Chem. 262: 260-264.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 260-264
-
-
Hosie, L.1
Sutton, L.D.2
Quinn, D.M.3
-
30
-
-
0018178434
-
A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
-
Markwell, M. K., S. M. Haas, L. L. Bieber, and N. E. Tolbert. 1978. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal. Biochem. 87: 206-210.
-
(1978)
Anal. Biochem.
, vol.87
, pp. 206-210
-
-
Markwell, M.K.1
Haas, S.M.2
Bieber, L.L.3
Tolbert, N.E.4
-
31
-
-
0018161396
-
Procedure for determination of free and total cholesterol in micro- or nanogram amounts suitable for studies with cultured cells
-
Gamble, W., M. Vaughan, H. S. Kruth, and J. Avigan. 1978. Procedure for determination of free and total cholesterol in micro- or nanogram amounts suitable for studies with cultured cells. J. Lipid Res. 19: 1068-1070.
-
(1978)
J. Lipid Res.
, vol.19
, pp. 1068-1070
-
-
Gamble, W.1
Vaughan, M.2
Kruth, H.S.3
Avigan, J.4
-
32
-
-
0022549920
-
A receptor-mediated pathway for cholesterol homeostasis
-
Brown, M. S., and J. L. Goldstein. 1986. A receptor-mediated pathway for cholesterol homeostasis. Science. 232: 34-47.
-
(1986)
Science
, vol.232
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
33
-
-
0004161838
-
-
Cambridge University Press, Cambridge
-
Press, W. H., B. P. Flannery, S. A. Teukolsky, and W. T. Vetterling. 1986. Numerical Recipes. Cambridge University Press, Cambridge. 547-578.
-
(1986)
Numerical Recipes
, pp. 547-578
-
-
Press, W.H.1
Flannery, B.P.2
Teukolsky, S.A.3
Vetterling, W.T.4
-
34
-
-
0002606725
-
A new method of constrained optimization and a comparison with other methods
-
Box, M. J. 1968. A new method of constrained optimization and a comparison with other methods. Comp. J. 8: 45-52.
-
(1968)
Comp. J.
, vol.8
, pp. 45-52
-
-
Box, M.J.1
-
35
-
-
0028928737
-
Activation of acyl-coenzyme A:cholesterol acyltransferase by cholesterol or by oxysterol in a cell-free system
-
Cheng, D., C. C. Chang, X. Qu, and T. Y. Chang. 1995. Activation of acyl-coenzyme A:cholesterol acyltransferase by cholesterol or by oxysterol in a cell-free system. J. Biol. Chem. 270: 685-95.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 685-695
-
-
Cheng, D.1
Chang, C.C.2
Qu, X.3
Chang, T.Y.4
-
36
-
-
0030033241
-
Esterification of oxysterols in human serum: Effects on distribution and cellular uptake
-
Lin, C. Y., and D. W. Morel. 1996. Esterification of oxysterols in human serum: effects on distribution and cellular uptake. J. Lipid Res. 37: 168-178.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 168-178
-
-
Lin, C.Y.1
Morel, D.W.2
-
37
-
-
0023663531
-
Mechanisms and consequences of cellular cholesterol exchange and transfer
-
Phillips, M. C., W. J. Johnson, and G. H. Rothblat. 1987. Mechanisms and consequences of cellular cholesterol exchange and transfer. Biochim. Biophys. Acta. 906: 223-276.
-
(1987)
Biochim. Biophys. Acta
, vol.906
, pp. 223-276
-
-
Phillips, M.C.1
Johnson, W.J.2
Rothblat, G.H.3
-
38
-
-
0021148426
-
Cholesterol transfer from small and large unilamellar vesicles
-
McLean, L., and M. C. Phillips. 1984. Cholesterol transfer from small and large unilamellar vesicles. Biochim. Biophys. Acta. 776: 21-26.
-
(1984)
Biochim. Biophys. Acta
, vol.776
, pp. 21-26
-
-
McLean, L.1
Phillips, M.C.2
-
39
-
-
0024539791
-
The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts
-
Liscum, L., R. M. Ruggiero, and J. R. Faust. 1989. The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts. J. Cell Biol. 108: 1625-1636.
-
(1989)
J. Cell Biol.
, vol.108
, pp. 1625-1636
-
-
Liscum, L.1
Ruggiero, R.M.2
Faust, J.R.3
-
40
-
-
0028999147
-
Movement of 25-hydroxycholesterol from the plasma membrane to the rough endoplasmic reticulum in cultured hepatoma cells
-
Lange, Y., J. Ye, and F. Strebel. 1995. Movement of 25-hydroxycholesterol from the plasma membrane to the rough endoplasmic reticulum in cultured hepatoma cells. J. Lipid Res. 36: 1092-1097.
-
(1995)
J. Lipid Res.
, vol.36
, pp. 1092-1097
-
-
Lange, Y.1
Ye, J.2
Strebel, F.3
-
41
-
-
0022380793
-
Cholesterol-rich intracellular membranes: A precursor to the plasma membrane
-
Lange, Y., and T. L. Steck. 1985. Cholesterol-rich intracellular membranes: a precursor to the plasma membrane. J. Biol. Chem. 260: 15592-15597.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 15592-15597
-
-
Lange, Y.1
Steck, T.L.2
-
42
-
-
0025142335
-
Cholesterol and vesicular stomatitis virus G protein take separate routes from the endoplasmic reticulum to the plasma membrane
-
Urbani, L., and R. D. Simoni. 1990. Cholesterol and vesicular stomatitis virus G protein take separate routes from the endoplasmic reticulum to the plasma membrane. J. Biol. Chem. 265: 1919-1923.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 1919-1923
-
-
Urbani, L.1
Simoni, R.D.2
-
43
-
-
0025065068
-
Regulation of phospholipid biosynthesis during cholesterol influx and high density lipoprotein-mediated cholesterol efflux in macrophages
-
Schmitz, G. M. Beuck, G. Nowicka, and H. Robenek. 1990. Regulation of phospholipid biosynthesis during cholesterol influx and high density lipoprotein-mediated cholesterol efflux in macrophages. J. Lipid Res. 31: 1741-1752.
-
(1990)
J. Lipid Res.
, vol.31
, pp. 1741-1752
-
-
Schmitz1
Beuck, G.M.2
Nowicka, G.3
Robenek, H.4
-
44
-
-
0026686511
-
Binary phase behavior of angiotoxic oxidized cholesterols with cholesterol
-
Dorset, D. L. 1992. Binary phase behavior of angiotoxic oxidized cholesterols with cholesterol. Biochim. Biophys. Acta. 1127: 293-297.
-
(1992)
Biochim. Biophys. Acta
, vol.1127
, pp. 293-297
-
-
Dorset, D.L.1
-
45
-
-
0026597885
-
Rates of spontaneous exchange of synthetic radiolabeled sterols between lipid vesicles
-
Kan, C. C., J. Yan, and R. Bittman. 1992. Rates of spontaneous exchange of synthetic radiolabeled sterols between lipid vesicles. Biochemistry. 31: 1866-1874.
-
(1992)
Biochemistry
, vol.31
, pp. 1866-1874
-
-
Kan, C.C.1
Yan, J.2
Bittman, R.3
-
46
-
-
0028901372
-
Apolipoprotein A-I-mediated efflux of sterols from oxidized LDL-loaded macrophages
-
Kritharides, L., W. Jessup, E. L. Mander, and R. T. Davis. 1995. Apolipoprotein A-I-mediated efflux of sterols from oxidized LDL-loaded macrophages. Arterioscler. Thromb. Vasc. Biol. 15: 276-289.
-
(1995)
Arterioscler. Thromb. Vasc. Biol.
, vol.15
, pp. 276-289
-
-
Kritharides, L.1
Jessup, W.2
Mander, E.L.3
Davis, R.T.4
-
47
-
-
0028362152
-
Oxidized low density lipoprotein leads to macrophage accumulation of unesterified cholesterol as a result of lysosomal trapping of the lipoprotein hydrolyzed cholesteryl ester
-
Maor, I., and M. Aviram. 1995. Oxidized low density lipoprotein leads to macrophage accumulation of unesterified cholesterol as a result of lysosomal trapping of the lipoprotein hydrolyzed cholesteryl ester. J. Lipid Res. 35: 803-819.
-
(1995)
J. Lipid Res.
, vol.35
, pp. 803-819
-
-
Maor, I.1
Aviram, M.2
|