Human and rodent type 1 11β-hydroxysteroid dehydrogenases are 7β-hydroxycholesterol dehydrogenases involved in oxysterol metabolism

Cellular and Molecular Life Sciences

Volumn 61, Issue 7-8, 2004, Pages 992-999

  Hult, M ^a   Elleby, B ^b   Shafqat, N ^a   Svensson, S ^b   Rane, A ^c   Jornvall H ^a   Abrahmsen, L ^b   Oppermann, U ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b BIOVITRUM AB   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

11 hydroxysteroid dehydrogenase; 7 hydroxysteroid dehydrogenase; Glucocorticoid metabolism; Metabolic syndrome; Oxysterol metabolism

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 7 OXOCHOLESTEROL; 7ALPHA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL DEHYDROGENASE; CORTISONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; ISOENZYME; OXIDOREDUCTASE; OXYSTEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; HAMSTER; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LINEAR REGRESSION ANALYSIS; LIVER; LIVER MICROSOME; METABOLIC REGULATION; METABOLIC SYNDROME X; MICHAELIS MENTEN KINETICS; MOUSE; NONHUMAN; RAT; STEROID METABOLISM; STEROIDOGENESIS;

ANIMALIA; CRICETINAE; RODENTIA;

EID: 2442614716     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3476-y     Document Type: Article

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