Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against oxidized low-density lipoprotein and oxysterols

Atherosclerosis

Volumn 155, Issue 2, 2001, Pages 445-453

  Yasunobu, Yuji ^a,b   Hayashi, Kozo ^a   Shingu, Tetsuji ^a   Yamagata, Togo ^a   Kajiyama, Goro ^a   Kambe, Masayuki ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b Miyoshi Medical Association Hospital   (Japan)

Author keywords

Autoantibody; Coronary angiography; Oxidized low density lipoprotein; Oxysterol; Stenosis; Unstable angina

Indexed keywords

25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; ANTIBODY; AUTOANTIBODY; OXIDIZED LOW DENSITY LIPOPROTEIN; OXYSTEROL;

ADULT; AGED; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ANTIBODY BLOOD LEVEL; ARTICLE; ATHEROGENESIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; FEMALE; HUMAN; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; STENOSIS; UNSTABLE ANGINA PECTORIS;

ADULT; AGED; AGED, 80 AND OVER; ANGINA PECTORIS; ANGINA, UNSTABLE; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; CORONARY ARTERIOSCLEROSIS; CORONARY VASOSPASM; FEMALE; HUMANS; HYDROXYCHOLESTEROLS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; OXIDATIVE STRESS; RISK FACTORS;

EID: 0035091665     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(00)00581-5     Document Type: Article

References (60)

1. Beyond cholesterol; modifications of low-density lipoprotein that increase its atherogenesity
2. Role of oxidized low-density lipoprotein in atherogenesis
3. Role of oxidatively modified LDL in atherosclerosis
4. Modification of human serum low-density lipoprotein by oxidation-characterization and pathophysiological implications
5. Oxysterols and atherosclerosis
6. Biological effects of oxysterols: Current status
7. Low-density lipoprotein undergoes oxidative modification in vivo
8. Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits
9. Evidence for the presence of oxidatively modified low-density lipoprotein in atherosclerotic lesions of rabbit and man
10. Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits
11. Serum antibodies to oxidized low-density lipoprotein and ceroid in chronic periaortitis
12. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low-density lipoprotein
13. Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL
14. Oxidized low-density lipoproteins facilitate leukocyte adhesion to aortic intima without affecting endothelium-dependent relaxation. Role of P-selection
15. Contrary effects of lightly and strongly oxidized LDL with potent promotion of growth versus apoptosis on arterial smooth muscle cells, macrophages, and fibroblasts
16. Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases
17. Oxidized LDLs induce massive apoptosis of cultured human endothelial cells through a calcium-dependent pathway
18. Modified low-density lipoprotein is a potent stimulus for smooth muscle cell outgrowth from rat aortic explant in vitro
19. Decreased HDL cholesterol in prepubertal and pubertal children of CHD patients
20. HDL cholesterol levels in patients with myocardial infarction and their families
21. Oxysterols in cap and core of human advanced atherosclerotic lesions
22. 7-Hydroperoxycholesterol and its product in oxidized low-density lipoprotein and human atherosclerotic plaque
23. Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaques
24. Sterol metabolism - XLVII. Oxidized cholesterol esters in human tissues
25. Inhibitors of sterol synthesis. Chromatography of acetate derivatives of oxygenated sterols
26. Determination of cholesterol oxidation products in human plasma by isotope dilution mass spectrometry
27. Cytotoxicity of oxidized LDL to porcine aortic smooth cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol
28. Oxysterol-induced endothelial cell dysfunction in culture
29. Biological activities of oxysterols
30. Macrophages, lipid oxidation, ceroid accumulation and alpha-tocopherol depletion in human atherosclerotic lesions
31. Different patterns of IL-1β secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7α-, 7β-hydroxycholesterol, or 7-ketocholesterol
32. The role of lipid peroxidation and antioxidants in oxidative modification of LDL
33. Clinical significance of antibodies against oxidized low-density lipoprotein in early RA
34. Autoantibodies to oxidized low-density lipoproteins in NIDDM are inversely related to metabolic control and microvascular complications
35. Autoantibodies against modified low-density lipoprotein. Non-lipid factor of blood plasma that stimulates foam cell formation
36. Autoantibody against oxidized LDL and progression of carotid atherosclerosis
37. Specificity of autoantibodies against oxidized LDL as an additional marker for atherosclerotic risk
38. ELISA of IgG antibody to oxidized low-density lipoprotein: Effects of blocking buffer and method of data expression
39. Antibodies against cardiolipin and oxidatively modified LDL in 50-year-old men predict myocardial infarction
40. Autoantibodies against oxidized low-density lipoproteins in patients with coronary disease
41. Autoantibodies against oxidized low-density lipoprotein in patients with angiographically verified coronary artery disease
42. Autoantibody titers to oxidized low-density lipoprotein in patients with coronary atherosclerosis
43. Unstable angina. A classification
44. Decreases in plasma lipid content and thrombotic activity by ethyl icosapentate purified from fish oils
45. New method for assaying free and total cholesterol in cultured cells by high-pressure liquid chromatography
46. Hypolipidemic effect of beraprost sodium in patients with arteriosclerosis obliterans accompanied by hyperlipidemia
47. LDL oxidation in patients with severe carotid atherosclerosis: A study of in vitro and in vivo oxidation markers
48. Patients with early-onset peripheral vascular disease have increased levels of autoantibodies against oxidized LDL
49. Is oxidative stress causally linked to unstable angina pectoris? A study in 100 CAD patients and matched controls
50. The radicals in cigarette tar: Their nature and suggested physiological implications
51. The relation of diet, cigarette smoking, and alcohol consumption to plasma β-carotene and α-tocopherol levels
52. Effect of vitamin C and E supplementation on susceptibility of plasma lipoproteins to peroxidation induced by acute smoking
53. Cigarette smoking potentiates endothelial dysfunction of forearm resistance vessels in patients with hypercholesterolemia. Role of oxidized LDL
54. Supplementation with vitamin E but not β-carotene in vivo protects low-density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking
55. Nitric oxide protects against alkyl peroxide-mediated cytotoxicity: Further insights into the role nitric oxide plays in oxidative stress
56. A new role for vascular endothelial growth factor and fibroblast growth factors: Increasing endothelial resistance to oxidative stress
57. Lipoprotein oxidation and progression of carotid atherosclerosis
58. Increased plasma 7-β-hydroxycholesterol concentrations in a population with a high risk for cardiovascular disease
59. Oxidized lipids in the diet are a source of oxidized lipids in chylomicrons of human serum
60. Lipids and oxidized lipids in human atherosclerotic lesions at different stages of development