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Volumn , Issue , 2009, Pages 1-52

Bioavailability and metabolism of dietary flavonoids - much known - much more to discover

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EID: 84882752892     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (6)

References (275)
  • 4
    • 33744901669 scopus 로고    scopus 로고
    • The effect of chronic consumption of red wine polyphenols on vascular function in postmenopausal women
    • Naissides, M.; Pal, S.; Mamo, J. C. L.; James, A. P.; and Dhaliwal, S. (2006). The effect of chronic consumption of red wine polyphenols on vascular function in postmenopausal women. European Journal of Clinical Nutrition, 60, 740-745.
    • (2006) European Journal of Clinical Nutrition , vol.60 , pp. 740-745
    • Naissides, M.1    Pal, S.2    Mamo, J.C.L.3    James, A.P.4    Dhaliwal, S.5
  • 5
    • 33846661267 scopus 로고    scopus 로고
    • Does flavanol intake influence mortality from nitric oxide-dependent processes? Ischemic heart disease, stroke, diabetes mellitus, and cancer in Panama
    • Bayard, V.; Chamorro, F.; Motta, J.; and Hollenberg, N. K. (2007). Does flavanol intake influence mortality from nitric oxide-dependent processes? Ischemic heart disease, stroke, diabetes mellitus, and cancer in Panama. International Journal of Medical Sciences, 4, 53-58.
    • (2007) International Journal of Medical Sciences , vol.4 , pp. 53-58
    • Bayard, V.1    Chamorro, F.2    Motta, J.3    Hollenberg, N.K.4
  • 6
    • 32844466487 scopus 로고    scopus 로고
    • Is reversal of endothelial dysfunction by tea related to flavonoid metabolism?
    • Hodgson, J. M.; Puddey, I. B.; Burke, V.; and Croft, K. D. (2006). Is reversal of endothelial dysfunction by tea related to flavonoid metabolism? British Journal of Nutrition, 95, 14-17.
    • (2006) British Journal of Nutrition , vol.95 , pp. 14-17
    • Hodgson, J.M.1    Puddey, I.B.2    Burke, V.3    Croft, K.D.4
  • 7
    • 9744242794 scopus 로고    scopus 로고
    • Dietary flavonoids and cancer risk: Evidence from human population studies
    • Neuhouser, M. L. (2004). Dietary flavonoids and cancer risk: Evidence from human population studies. Nutrition and Cancer, 50, 1-7.
    • (2004) Nutrition and Cancer , vol.50 , pp. 1-7
    • Neuhouser, M.L.1
  • 9
    • 0027504187 scopus 로고
    • Dietary antioxidant Ffonoids and risk of coronary heart-disease -the Zutphen Elderly Study
    • Hertog, M. G. L.; Feskens, E. J. M.; Hollman, P. C. H.; Katan, M. B.; and Kromhout, D. (1993). Dietary antioxidant Ffonoids and risk of coronary heart-disease -the Zutphen Elderly Study. Lancet, 342, 1007.
    • (1993) Lancet , vol.342 , pp. 1007
    • Hertog, M.G.L.1    Feskens, E.J.M.2    Hollman, P.C.H.3    Katan, M.B.4    Kromhout, D.5
  • 13
    • 38549136863 scopus 로고    scopus 로고
    • Polyphenolic phytochemicals -just antioxidants or much more?
    • Stevenson, D. E.; and Hurst, R. D. (2007). Polyphenolic phytochemicals -just antioxidants or much more? Cellular and Molecular Life Sciences, 64, 2900-2916.
    • (2007) Cellular and Molecular Life Sciences , vol.64 , pp. 2900-2916
    • Stevenson, D.E.1    Hurst, R.D.2
  • 15
    • 48449083346 scopus 로고    scopus 로고
    • Microbial metabolism of dietary phenolic compounds in the colon
    • Aura, A.-M. (2008). Microbial metabolism of dietary phenolic compounds in the colon. Phytochemistry Reviews, 7, 407-429.
    • (2008) Phytochemistry Reviews , vol.7 , pp. 407-429
    • Aura, A.-M.1
  • 16
    • 12144262315 scopus 로고    scopus 로고
    • Diet-derivedPhenols in plasma and tissues and their implications for health
    • Clifford, M. N. (2004). Diet-derivedPhenols in plasma and tissues and their implications for health. Planta Medica, 70, 1103-1114.
    • (2004) Planta Medica , vol.70 , pp. 1103-1114
    • Clifford, M.N.1
  • 17
    • 19544378483 scopus 로고    scopus 로고
    • Polyphenols: dietary components with established benefits to health?
    • Kroon, P.; and Williamson, G. (2005). Polyphenols: dietary components with established benefits to health? Journal of the Science of Food and Agriculture, 85, 1239-1240.
    • (2005) Journal of the Science of Food and Agriculture , vol.85 , pp. 1239-1240
    • Kroon, P.1    Williamson, G.2
  • 19
    • 4043089112 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of dietary flavonoids in humans
    • Manach, C.; and Donovan, J. L. (2004). Pharmacokinetics and metabolism of dietary flavonoids in humans. Free Radical Research, 38, 771-785.
    • (2004) Free Radical Research , vol.38 , pp. 771-785
    • Manach, C.1    Donovan, J.L.2
  • 21
    • 1642528478 scopus 로고    scopus 로고
    • Absorption and metabolism of flavonoids
    • Walle, T. (2004). Absorption and metabolism of flavonoids. Free Radical Biology and Medicine, 36, 829-837.
    • (2004) Free Radical Biology and Medicine , vol.36 , pp. 829-837
    • Walle, T.1
  • 22
    • 1642550954 scopus 로고    scopus 로고
    • The use of flavonoid aglycones in in vitro systems to test biological activities: based on bioavailability data, is this a valid approach?
    • Williamson, G. (2002). The use of flavonoid aglycones in in vitro systems to test biological activities: based on bioavailability data, is this a valid approach? Phytochemistry Reviews, V1, 215-222.
    • (2002) Phytochemistry Reviews , vol.1 , pp. 215-222
    • Williamson, G.1
  • 23
    • 13844271387 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
    • Williamson, G.; and Manach, C. (2005). Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. American Journal of Clinical Nutrition, 81, 243S-255S.
    • (2005) American Journal of Clinical Nutrition , vol.81
    • Williamson, G.1    Manach, C.2
  • 24
    • 0036669547 scopus 로고    scopus 로고
    • Absorption and metabolism of polyphenols in the gut and impact on health
    • Scalbert, A.; Morand, C.; Manach, C.; and Remesy, C. (2002). Absorption and metabolism of polyphenols in the gut and impact on health. Biomedicine and Pharmacotherapy, 56, 276-282.
    • (2002) Biomedicine and Pharmacotherapy , vol.56 , pp. 276-282
    • Scalbert, A.1    Morand, C.2    Manach, C.3    Remesy, C.4
  • 26
    • 78649927252 scopus 로고    scopus 로고
    • Dietary flavonoids and health -broadening the perspective
    • O. M. Andersen; and K. R. Markham (Eds.), Boca Raton: CRC Press
    • Clifford, M. N.; and Brown, J. E. (2006). Dietary flavonoids and health -broadening the perspective. In O. M. Andersen; and K. R. Markham (Eds.), Flavonoids: Chemistry, Biochemistry and Applications (pp. 319-370). Boca Raton: CRC Press.
    • (2006) Flavonoids: Chemistry, Biochemistry and Applications , pp. 319-370
    • Clifford, M.N.1    Brown, J.E.2
  • 27
    • 33746835408 scopus 로고    scopus 로고
    • Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans
    • Kay, C. D. (2006). Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans. Nutrition Research Reviews, 19, 137-146.
    • (2006) Nutrition Research Reviews , vol.19 , pp. 137-146
    • Kay, C.D.1
  • 28
    • 34447540210 scopus 로고    scopus 로고
    • The bioavailability and absorption of anthocyanins: Towards a better understanding
    • McGhie, T. K.; and Walton, M. C. (2007). The bioavailability and absorption of anthocyanins: Towards a better understanding. Molecular Nutrition and Food Research, 51, 702-713.
    • (2007) Molecular Nutrition and Food Research , vol.51 , pp. 702-713
    • McGhie, T.K.1    Walton, M.C.2
  • 29
    • 37549066909 scopus 로고    scopus 로고
    • Intestinal and hepatic glucuronidation of flavonoids
    • Zhang, L.; Zuo, Z.; and Lin, G. (2007). Intestinal and hepatic glucuronidation of flavonoids. Molecular Pharmaceutics, 4, 833-845.
    • (2007) Molecular Pharmaceutics , vol.4 , pp. 833-845
    • Zhang, L.1    Zuo, Z.2    Lin, G.3
  • 30
    • 45849115105 scopus 로고    scopus 로고
    • The key importance of soy isoflavone bioavailability to understanding health benefits
    • Larkin, T.; Price, W. E.; and Astheimer, L. (2008). The key importance of soy isoflavone bioavailability to understanding health benefits. Critical Reviews in Food Science and Nutrition, 48, 538-552.
    • (2008) Critical Reviews in Food Science and Nutrition , vol.48 , pp. 538-552
    • Larkin, T.1    Price, W.E.2    Astheimer, L.3
  • 32
    • 11844269306 scopus 로고    scopus 로고
    • Flavonoid glucosides are hydrolyzed and thus activated in the oral cavity in humans
    • Walle, T.; Browning, A. M.; Steed, L. L.; Reed, S. G.; and Walle, U. K. (2005). Flavonoid glucosides are hydrolyzed and thus activated in the oral cavity in humans. Journal of Nutrition, 135, 48-52.
    • (2005) Journal of Nutrition , vol.135 , pp. 48-52
    • Walle, T.1    Browning, A.M.2    Steed, L.L.3    Reed, S.G.4    Walle, U.K.5
  • 38
    • 58649107910 scopus 로고    scopus 로고
    • A viscous food matrix influences absorption and excretion but not metabolism of blackcurrant anthocyanins in rats
    • Walton, M. C.; Hendriks, W. H.; Broomfield, A. M.; and McGhie, T. (2009). A viscous food matrix influences absorption and excretion but not metabolism of blackcurrant anthocyanins in rats. Journal of Food Science, 74, H22-H29.
    • (2009) Journal of Food Science , vol.74
    • Walton, M.C.1    Hendriks, W.H.2    Broomfield, A.M.3    McGhie, T.4
  • 41
    • 32344446760 scopus 로고    scopus 로고
    • Role of Caco-2 cell monolayers in prediction of intestinal drug absorption
    • Shah, P.; Jogani, V.; Bagchi, T.; and Misra, A. (2006). Role of Caco-2 cell monolayers in prediction of intestinal drug absorption. Biotechnology Progress, 22, 186-198.
    • (2006) Biotechnology Progress , vol.22 , pp. 186-198
    • Shah, P.1    Jogani, V.2    Bagchi, T.3    Misra, A.4
  • 42
    • 0141742373 scopus 로고    scopus 로고
    • Metabolism of flavonoids via enteric recycling: Mechanistic studies of disposition of apigenin in the Caco-2 cell culture model
    • Hu, M.; Chen, J.; and Lin, H. M. (2003). Metabolism of flavonoids via enteric recycling: Mechanistic studies of disposition of apigenin in the Caco-2 cell culture model. Journal of Pharmacology and Experimental Therapeutics, 307, 314-321.
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.307 , pp. 314-321
    • Hu, M.1    Chen, J.2    Lin, H.M.3
  • 46
    • 0037219688 scopus 로고    scopus 로고
    • Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans
    • Nemeth, K.; Plumb, G. W.; Berrin, J.-G.; Juge, N.; Jacob, R.; Naim, H. Y.; Williamson, G.; Swallow, D. M.; and Kroon, P. A. (2003). Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans. European Journal of Nutrition, 42, 29-42.
    • (2003) European Journal of Nutrition , vol.42 , pp. 29-42
    • Nemeth, K.1    Plumb, G.W.2    Berrin, J.-G.3    Juge, N.4    Jacob, R.5    Naim, H.Y.6    Williamson, G.7    Swallow, D.M.8    Kroon, P.A.9
  • 48
    • 0032566518 scopus 로고    scopus 로고
    • Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity
    • Day, A. J.; DuPont, M. S.; Ridley, S.; Rhodes, M.; Rhodes, M. J. C.; Morgan, M. R. A.; and Williamson, G. (1998). Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity. FEBS Letters, 436, 71-75.
    • (1998) FEBS Letters , vol.436 , pp. 71-75
    • Day, A.J.1    DuPont, M.S.2    Ridley, S.3    Rhodes, M.4    Rhodes, M.J.C.5    Morgan, M.R.A.6    Williamson, G.7
  • 49
    • 0033734729 scopus 로고    scopus 로고
    • Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway
    • Gee, J. M.; DuPont, M. S.; Day, A. J.; Plumb, G. W.; Williamson, G.; and Johnson, I. T. (2000). Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway. Journal of Nutrition, 130, 2765-2771.
    • (2000) Journal of Nutrition , vol.130 , pp. 2765-2771
    • Gee, J.M.1    DuPont, M.S.2    Day, A.J.3    Plumb, G.W.4    Williamson, G.5    Johnson, I.T.6
  • 50
    • 3142621340 scopus 로고    scopus 로고
    • The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides
    • Arts, I. C. W.; Sesink, A. L. A.; Faassen-Peters, M.; and Hollman, P. C. H. (2004). The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides. British Journal of Nutrition, 91, 841-847.
    • (2004) British Journal of Nutrition , vol.91 , pp. 841-847
    • Arts, I.C.W.1    Sesink, A.L.A.2    Faassen-Peters, M.3    Hollman, P.C.H.4
  • 52
    • 41849125317 scopus 로고    scopus 로고
    • Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones
    • Serra, H.; Mendes, T.; Bronze, M. R.; and Simplicio, A.L. (2008). Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones. Bioorganic and Medicinal Chemistry, 16, 4009-4018.
    • (2008) Bioorganic and Medicinal Chemistry , vol.16 , pp. 4009-4018
    • Serra, H.1    Mendes, T.2    Bronze, M.R.3    Simplicio, A.L.4
  • 55
  • 57
    • 23744497186 scopus 로고    scopus 로고
    • Role of intestinal first-pass metabolism of baicalein in its absorption process
    • Zhang, L.; Lin, G.; Chang, Q.; and Zuo, Z. (2005). Role of intestinal first-pass metabolism of baicalein in its absorption process. Pharmaceutical Research, 22, 10501058.
    • (2005) Pharmaceutical Research , vol.22 , pp. 1058
    • Zhang, L.1    Lin, G.2    Chang, Q.3    Zuo, Z.4
  • 58
    • 33644769388 scopus 로고    scopus 로고
    • The bioavailability of polyphenols is highly governed by the capacity of the intestine and of the liver to secrete conjugated metabolites
    • Silberberg, M.; Morand, C.; Mathevon, T.; Besson, C.; Manach, C.; Scalbert, A.; and Remesy, C. (2005). The bioavailability of polyphenols is highly governed by the capacity of the intestine and of the liver to secrete conjugated metabolites. European Journal of Nutrition, 45, 88-96.
    • (2005) European Journal of Nutrition , vol.45 , pp. 88-96
    • Silberberg, M.1    Morand, C.2    Mathevon, T.3    Besson, C.4    Manach, C.5    Scalbert, A.6    Remesy, C.7
  • 60
  • 62
    • 39849096862 scopus 로고    scopus 로고
    • Assessment of intestinal absorption of vitexin-2"-O-rhamnoside in hawthorn leaves flavonoids in rat using in situ and in vitro absorption models
    • Xu, Y. A.; Fan, G. R.; Gao, S.; and Hong, Z. Y. (2008). Assessment of intestinal absorption of vitexin-2"-O-rhamnoside in hawthorn leaves flavonoids in rat using in situ and in vitro absorption models. Drug Development and Industrial Pharmacy, 34, 164-170.
    • (2008) Drug Development and Industrial Pharmacy , vol.34 , pp. 164-170
    • Xu, Y.A.1    Fan, G.R.2    Gao, S.3    Hong, Z.Y.4
  • 65
    • 37549024168 scopus 로고    scopus 로고
    • Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption
    • Walle, T. (2007). Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption. Molecular Pharmaceutics, 4, 826-832.
    • (2007) Molecular Pharmaceutics , vol.4 , pp. 826-832
    • Walle, T.1
  • 66
    • 34548423695 scopus 로고    scopus 로고
    • Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?
    • Walle, T. (2007). Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass? Seminars in Cancer Biology, 17, 354-362.
    • (2007) Seminars in Cancer Biology , vol.17 , pp. 354-362
    • Walle, T.1
  • 68
    • 35548940326 scopus 로고    scopus 로고
    • Bioavailable flavonoids: Cytochrome P450mediated metabolism of methoxyflavones
    • Walle, U. K.; and Walle, T. (2007). Bioavailable flavonoids: Cytochrome P450mediated metabolism of methoxyflavones. Drug Metabolism and Disposition, 35, 1985-1989.
    • (2007) Drug Metabolism and Disposition , vol.35 , pp. 1985-1989
    • Walle, U.K.1    Walle, T.2
  • 69
    • 0037300834 scopus 로고    scopus 로고
    • Metabolism of quercetin-7-and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism
    • O'Leary, K. A.; Day, A. J.; Needs, P. W.; Mellon, F. A.; O'Brien, N. M.; and Williamson, G. (2003). Metabolism of quercetin-7-and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism. Biochemical Pharmacology, 65, 479-491.
    • (2003) Biochemical Pharmacology , vol.65 , pp. 479-491
    • O'Leary, K.A.1    Day, A.J.2    Needs, P.W.3    Mellon, F.A.4    O'Brien, N.M.5    Williamson, G.6
  • 71
    • 39049094079 scopus 로고    scopus 로고
    • Processing blackcurrants dramatically reduces the content and does not enhance the urinary yield of anthocyanins in human subjects
    • Hollands, W.; Brett, G. M.; Radreau, P.; Saha, S.; Teucher, B.; Bennett, R. N.; and Kroon, P. A. (2008). Processing blackcurrants dramatically reduces the content and does not enhance the urinary yield of anthocyanins in human subjects. Food Chemistry, 108, 869-878.
    • (2008) Food Chemistry , vol.108 , pp. 869-878
    • Hollands, W.1    Brett, G.M.2    Radreau, P.3    Saha, S.4    Teucher, B.5    Bennett, R.N.6    Kroon, P.A.7
  • 72
    • 33749241899 scopus 로고    scopus 로고
    • Anthocyanins: Structural characteristics that result in unique metabolic patterns and biological activities
    • Prior, R. L.; and Wu, X. L. (2006). Anthocyanins: Structural characteristics that result in unique metabolic patterns and biological activities. Free Radical Research, 40, 1014-1028.
    • (2006) Free Radical Research , vol.40 , pp. 1014-1028
    • Prior, R.L.1    Wu, X.L.2
  • 76
    • 11244283773 scopus 로고    scopus 로고
    • Absorption of acylated anthocyanins in rats and humans after ingesting an extract of Ipomoea batatas purple sweet potato tuber
    • Harada, K.; Kano, M.; Takayanagi, T.; Yamakawa, O.; and Ishikawa, F. (2004). Absorption of acylated anthocyanins in rats and humans after ingesting an extract of Ipomoea batatas purple sweet potato tuber. Bioscience Biotechnology and Biochemistry, 68, 1500-1507.
    • (2004) Bioscience Biotechnology and Biochemistry , vol.68 , pp. 1500-1507
    • Harada, K.1    Kano, M.2    Takayanagi, T.3    Yamakawa, O.4    Ishikawa, F.5
  • 79
    • 34047225839 scopus 로고    scopus 로고
    • Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract
    • Chen, T.; Li, L. P.; Lu, X. Y.; Jiang, H. D.; and Zeng, S. (2007). Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract. Journal of Agricultural and Food Chemistry, 55, 273-277.
    • (2007) Journal of Agricultural and Food Chemistry , vol.55 , pp. 273-277
    • Chen, T.1    Li, L.P.2    Lu, X.Y.3    Jiang, H.D.4    Zeng, S.5
  • 81
    • 0034534704 scopus 로고    scopus 로고
    • Balicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form
    • Akao, T.; Kawabata, K.; Yanagisawa, E.; Ishihara, K.; Mizuhara, Y.; Wakui, Y.; Sakashita, Y.; and Kobashi, K. (2000). Balicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form. Journal of Pharmacy and Pharmacology, 52, 1563.
    • (2000) Journal of Pharmacy and Pharmacology , vol.52 , pp. 1563
    • Akao, T.1    Kawabata, K.2    Yanagisawa, E.3    Ishihara, K.4    Mizuhara, Y.5    Wakui, Y.6    Sakashita, Y.7    Kobashi, K.8
  • 82
    • 33748891217 scopus 로고    scopus 로고
    • Bioavailability and Tissue Distribution of Anthocyanins in Bilberry (Vaccinium myrtillus L.) Extract in Rats
    • Ichiyanagi, T.; Shida, Y.; Rahman, M. M.; Hatano, Y.; and Konishi, T. (2006). Bioavailability and Tissue Distribution of Anthocyanins in Bilberry (Vaccinium myrtillus L.) Extract in Rats. Journal of Agricultural and Food Chemistry, 54, 65786587.
    • (2006) Journal of Agricultural and Food Chemistry , vol.54 , pp. 65786587
    • Ichiyanagi, T.1    Shida, Y.2    Rahman, M.M.3    Hatano, Y.4    Konishi, T.5
  • 88
    • 33845600030 scopus 로고    scopus 로고
    • Uptake and distribution of catechins in fetal organs following in utero exposure in rats
    • Chu, K. O.; Wang, C. C.; Chu, C. Y.; Choy, K. W.; Pang, C. P.; and Rogers, M. S. (2006). Uptake and distribution of catechins in fetal organs following in utero exposure in rats. Human Reproduction, 22, 280-287.
    • (2006) Human Reproduction , vol.22 , pp. 280-287
    • Chu, K.O.1    Wang, C.C.2    Chu, C.Y.3    Choy, K.W.4    Pang, C.P.5    Rogers, M.S.6
  • 90
    • 0031595920 scopus 로고    scopus 로고
    • Wide distribution of H-3 (-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue
    • Suganuma, M.; Okabe, S.; Oniyama, M.; Tada, Y.; Ito, H.; and Fujiki, H. (1998). Wide distribution of H-3 (-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue. Carcinogenesis, 19, 1771-1776.
    • (1998) Carcinogenesis , vol.19 , pp. 1771-1776
    • Suganuma, M.1    Okabe, S.2    Oniyama, M.3    Tada, Y.4    Ito, H.5    Fujiki, H.6
  • 92
    • 0032930287 scopus 로고    scopus 로고
    • Absorption and metabolism of cyanidin 3O-[beta]-glucoside in rats
    • Tsuda, T.; Horio, F.; and Osawa, T. (1999). Absorption and metabolism of cyanidin 3O-[beta]-glucoside in rats. FEBS Letters, 449, 179-182.
    • (1999) FEBS Letters , vol.449 , pp. 179-182
    • Tsuda, T.1    Horio, F.2    Osawa, T.3
  • 93
    • 43549088339 scopus 로고    scopus 로고
    • Pharmacokinetics of the soybean isoflavone daidzein in its aglycone and glucoside form: a randomized, double-blind, crossover study
    • Ruefer, C. E.; Bub, A.; Moeseneder, J.; Winterhalter, P.; Stuertz, M.; and Kulling, S. E. (2008). Pharmacokinetics of the soybean isoflavone daidzein in its aglycone and glucoside form: a randomized, double-blind, crossover study. American Journal of Clinical Nutrition, 87, 1314-1323.
    • (2008) American Journal of Clinical Nutrition , vol.87 , pp. 1314-1323
    • Ruefer, C.E.1    Bub, A.2    Moeseneder, J.3    Winterhalter, P.4    Stuertz, M.5    Kulling, S.E.6
  • 95
    • 39149093653 scopus 로고    scopus 로고
    • Investigation of the metabolic fate of dihydrocaffeic acid
    • Poquet, L.; Clifford, M. N.; and Williamson, G. (2008). Investigation of the metabolic fate of dihydrocaffeic acid. Biochemical Pharmacology, 75, 1218-1229.
    • (2008) Biochemical Pharmacology , vol.75 , pp. 1218-1229
    • Poquet, L.1    Clifford, M.N.2    Williamson, G.3
  • 99
    • 34247212317 scopus 로고    scopus 로고
    • Pharmacokinetics of the citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects
    • Kanaze, F. I.; Bounartzi, M. I.; Georgarakis, M.; and Niopas, I. (2007). Pharmacokinetics of the citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects. European Journal of Clinical Nutrition, 61, 472-477.
    • (2007) European Journal of Clinical Nutrition , vol.61 , pp. 472-477
    • Kanaze, F.I.1    Bounartzi, M.I.2    Georgarakis, M.3    Niopas, I.4
  • 100
    • 12744272008 scopus 로고    scopus 로고
    • Determinants for urinary and plasma isoflavones in humans after soy intake
    • Franke, A. A.; Custer, L. J.; and Hundahl, S. A. (2004). Determinants for urinary and plasma isoflavones in humans after soy intake. Nutrition and Cancer, 50, 141-154.
    • (2004) Nutrition and Cancer , vol.50 , pp. 141-154
    • Franke, A.A.1    Custer, L.J.2    Hundahl, S.A.3
  • 104
    • 47949116376 scopus 로고    scopus 로고
    • Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects variability and possible use as biomarkers of polyphenol intake
    • Mennen, L. I.; Sapinho, D.; Ito, H.; Galan, P.; Hercberg, S.; and Scalbert, A. (2008). Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects variability and possible use as biomarkers of polyphenol intake. European Journal of Clinical Nutrition, 62, 519-525.
    • (2008) European Journal of Clinical Nutrition , vol.62 , pp. 519-525
    • Mennen, L.I.1    Sapinho, D.2    Ito, H.3    Galan, P.4    Hercberg, S.5    Scalbert, A.6
  • 105
    • 0034904141 scopus 로고    scopus 로고
    • Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats
    • Crespy, V.; Morand, C.; Besson, C.; Manach, C.; Demigne, C.; and Remesy, C. (2001). Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats. Journal of Nutrition, 131, 2109-2114.
    • (2001) Journal of Nutrition , vol.131 , pp. 2109-2114
    • Crespy, V.1    Morand, C.2    Besson, C.3    Manach, C.4    Demigne, C.5    Remesy, C.6
  • 106
    • 37749046852 scopus 로고    scopus 로고
    • Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry
    • Zhou, D. Y.; Xing, R.; Xu, Q.; Xue, X. Y.; Zhang, F. F.; and Liang, X. M. (2008). Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 46, 543-549.
    • (2008) Journal of Pharmaceutical and Biomedical Analysis , vol.46 , pp. 543-549
    • Zhou, D.Y.1    Xing, R.2    Xu, Q.3    Xue, X.Y.4    Zhang, F.F.5    Liang, X.M.6
  • 109
    • 0036229187 scopus 로고    scopus 로고
    • Procyanidins are not bioavailable in rats fed a single meal containing a grapeseed extract or the procyanidin dimer B-3
    • Donovan, J. L.; Manach, C.; Rios, L.; Morand, C.; Scalbert, A.; and Remesy, C. (2002). Procyanidins are not bioavailable in rats fed a single meal containing a grapeseed extract or the procyanidin dimer B-3. British Journal of Nutrition, 87, 299-306.
    • (2002) British Journal of Nutrition , vol.87 , pp. 299-306
    • Donovan, J.L.1    Manach, C.2    Rios, L.3    Morand, C.4    Scalbert, A.5    Remesy, C.6
  • 112
    • 25844526542 scopus 로고    scopus 로고
    • Quercetin appears in the lymph of unanesthetized rats as its phase II metabolites after administered into the stomach
    • Murota, K.; and Terao, J. (2005). Quercetin appears in the lymph of unanesthetized rats as its phase II metabolites after administered into the stomach. FEBS Letters, 579, 5343-5346.
    • (2005) FEBS Letters , vol.579 , pp. 5343-5346
    • Murota, K.1    Terao, J.2
  • 113
  • 115
    • 0035810344 scopus 로고    scopus 로고
    • Identification of quercetin glucuronides in human plasma by high-performance liquid chromatography-tandem mass spectrometry
    • Wittig, J.; Herderich, M.; Graefe, E. U.; and Veit, M. (2001). Identification of quercetin glucuronides in human plasma by high-performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography B, 753, 237-243.
    • (2001) Journal of Chromatography B , vol.753 , pp. 237-243
    • Wittig, J.1    Herderich, M.2    Graefe, E.U.3    Veit, M.4
  • 116
    • 33746698897 scopus 로고    scopus 로고
    • Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl-and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions
    • Mullen, W.; Edwards, C. A.; and Crozier, A. (2006). Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl-and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions. British Journal of Nutrition, 96, 107-116.
    • (2006) British Journal of Nutrition , vol.96 , pp. 107-116
    • Mullen, W.1    Edwards, C.A.2    Crozier, A.3
  • 118
    • 0037377562 scopus 로고    scopus 로고
    • Absorption of quercetin-3-glucoside and quercetin-4 '-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter
    • Day, A. J.; Gee, J. M.; DuPont, M. S.; Johnson, I. T.; and Williamson, G. (2003). Absorption of quercetin-3-glucoside and quercetin-4 '-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter. Biochemical Pharmacology, 65, 1199-1206.
    • (2003) Biochemical Pharmacology , vol.65 , pp. 1199-1206
    • Day, A.J.1    Gee, J.M.2    DuPont, M.S.3    Johnson, I.T.4    Williamson, G.5
  • 120
    • 33645535462 scopus 로고    scopus 로고
    • Red wine alcohol promotes quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro
    • Dragoni, S.; Gee, J.; Bennett, R.; Valoti, M.; and Sgaragli, G. (2006). Red wine alcohol promotes quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro. British Journal of Pharmacology, 147, 765-771.
    • (2006) British Journal of Pharmacology , vol.147 , pp. 765-771
    • Dragoni, S.1    Gee, J.2    Bennett, R.3    Valoti, M.4    Sgaragli, G.5
  • 122
    • 0037248470 scopus 로고    scopus 로고
    • Absorption of three wine-related polyphenols in three different matrices by healthy subjects
    • Goldberg, D. A.; Yan, J.; and Soleas, G. J. (2003). Absorption of three wine-related polyphenols in three different matrices by healthy subjects. Clinical Biochemistry, 36, 79-87.
    • (2003) Clinical Biochemistry , vol.36 , pp. 79-87
    • Goldberg, D.A.1    Yan, J.2    Soleas, G.J.3
  • 123
    • 0037418605 scopus 로고    scopus 로고
    • Distribution of C-14 -trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration
    • Vitrac, X.; Desmouliere, A.; Brouillaud, B.; Krisa, S.; Deffieux, G.; Barthe, N.; Rosenbaum, J.; and Merillon, J. M. (2003). Distribution of C-14 -trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration. Life Sciences, 72, 2219-2233.
    • (2003) Life Sciences , vol.72 , pp. 2219-2233
    • Vitrac, X.1    Desmouliere, A.2    Brouillaud, B.3    Krisa, S.4    Deffieux, G.5    Barthe, N.6    Rosenbaum, J.7    Merillon, J.M.8
  • 124
    • 33746093547 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration
    • Chen, X. Y.; Cui, L.; Duan, X. T.; Ma, B.; and Zhong, D. F. (2006). Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration. Drug Metabolism and Disposition, 34, 1345.
    • (2006) Drug Metabolism and Disposition , vol.34 , pp. 1345
    • Chen, X.Y.1    Cui, L.2    Duan, X.T.3    Ma, B.4    Zhong, D.F.5
  • 126
    • 0028029150 scopus 로고
    • Transcellular Transport of Benzoic Acid Across Caco-2 Cells by a pH-Dependent and Carrier-Mediated Transport Mechanism
    • Tsuji, A.; Takanaga, H.; Tamai, I.; and Terasaki, T. (1994). Transcellular Transport of Benzoic Acid Across Caco-2 Cells by a pH-Dependent and Carrier-Mediated Transport Mechanism. Pharmaceutical Research, 11, 30-37.
    • (1994) Pharmaceutical Research , vol.11 , pp. 30-37
    • Tsuji, A.1    Takanaga, H.2    Tamai, I.3    Terasaki, T.4
  • 127
    • 0031025460 scopus 로고    scopus 로고
    • Intestinal brush-border membrane transport of monocarboxylic acids mediated by proton-coupled transport and anion antiport mechanisms
    • Tamai, I.; Takanaga, H.; Maeda, H.; Yabuuchi, H.; Sai, Y.; Suzuki, Y.; and Tsuji, A. (1997). Intestinal brush-border membrane transport of monocarboxylic acids mediated by proton-coupled transport and anion antiport mechanisms. Journal of Pharmacy and Pharmacology, 49, 108-112.
    • (1997) Journal of Pharmacy and Pharmacology , vol.49 , pp. 108-112
    • Tamai, I.1    Takanaga, H.2    Maeda, H.3    Yabuuchi, H.4    Sai, Y.5    Suzuki, Y.6    Tsuji, A.7
  • 128
    • 2342612349 scopus 로고    scopus 로고
    • Transepithelial transport of pcoumaric acid and gallic acid in caco-2 cell monolayers
    • Konishi, Y.; Kobayashi, S.; and Shimizu, M. (2003). Transepithelial transport of pcoumaric acid and gallic acid in caco-2 cell monolayers. Bioscience Biotechnology and Biochemistry, 67, 2317-2324.
    • (2003) Bioscience Biotechnology and Biochemistry , vol.67 , pp. 2317-2324
    • Konishi, Y.1    Kobayashi, S.2    Shimizu, M.3
  • 129
    • 33846430488 scopus 로고    scopus 로고
    • Monocarboxylate transporter expression is associated with the absorption of benzoic acid in human intestinal epithelial cells
    • Haughton, E.; Clifford, M. N.; and Sharp, P. (2007). Monocarboxylate transporter expression is associated with the absorption of benzoic acid in human intestinal epithelial cells. Journal of the Science of Food and Agriculture, 87, 239-244.
    • (2007) Journal of the Science of Food and Agriculture , vol.87 , pp. 239-244
    • Haughton, E.1    Clifford, M.N.2    Sharp, P.3
  • 130
    • 47849094565 scopus 로고    scopus 로고
    • Absorption of black currant anthocyanins by monolayers of human intestinal epithelial Caco-2 cells mounted in using type chambers
    • Steinert, R. E.; Ditscheid, B.; Netzel, M.; and Jahreis, G. (2008). Absorption of black currant anthocyanins by monolayers of human intestinal epithelial Caco-2 cells mounted in using type chambers. Journal of Agricultural and Food Chemistry, 56, 4995-5001.
    • (2008) Journal of Agricultural and Food Chemistry , vol.56 , pp. 4995-5001
    • Steinert, R.E.1    Ditscheid, B.2    Netzel, M.3    Jahreis, G.4
  • 132
    • 0344629767 scopus 로고    scopus 로고
    • Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers
    • Konishi, Y.; Kobayashi, S.; and Shimizu, M. (2003). Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers. Journal of Agricultural and Food Chemistry, 51, 7296-7302.
    • (2003) Journal of Agricultural and Food Chemistry , vol.51 , pp. 7296-7302
    • Konishi, Y.1    Kobayashi, S.2    Shimizu, M.3
  • 133
    • 2342602459 scopus 로고    scopus 로고
    • Structural effects of phenolic acids on the transepithelial transport of fluorescein in Caco-2 cell monolayers
    • Konishi, Y.; Kubo, K.; and Shimizu, M. (2003). Structural effects of phenolic acids on the transepithelial transport of fluorescein in Caco-2 cell monolayers. Bioscience Biotechnology and Biochemistry, 67, 2014-2017.
    • (2003) Bioscience Biotechnology and Biochemistry , vol.67 , pp. 2014-2017
    • Konishi, Y.1    Kubo, K.2    Shimizu, M.3
  • 134
    • 36249009108 scopus 로고    scopus 로고
    • Interaction characteristics of flavonoids with human organic anion transporter 1 (hOAT1) and 3 (hOAT3)
    • Hong, S. S.; Seo, K.; Lim, S. C.; and Han, H. K. (2007). Interaction characteristics of flavonoids with human organic anion transporter 1 (hOAT1) and 3 (hOAT3). Pharmacological Research, 56, 468-473.
    • (2007) Pharmacological Research , vol.56 , pp. 468-473
    • Hong, S.S.1    Seo, K.2    Lim, S.C.3    Han, H.K.4
  • 135
    • 33745083616 scopus 로고    scopus 로고
    • Methylation protects dietary flavonoids from rapid hepatic metabolism
    • Wen, X.; and Walle, T. (2006). Methylation protects dietary flavonoids from rapid hepatic metabolism. Xenobiotica, 36, 387-397.
    • (2006) Xenobiotica , vol.36 , pp. 387-397
    • Wen, X.1    Walle, T.2
  • 136
    • 33748916241 scopus 로고    scopus 로고
    • Methylated flavonoids have greatly improved intestinal absorption and metabolic stability
    • Wen, X.; and Walle, T. (2006). Methylated flavonoids have greatly improved intestinal absorption and metabolic stability. Drug Metabolism and Disposition, 34, 1786-1792.
    • (2006) Drug Metabolism and Disposition , vol.34 , pp. 1786-1792
    • Wen, X.1    Walle, T.2
  • 137
    • 37549010675 scopus 로고    scopus 로고
    • Disposition of flavonoids via enteric recycling: Determination of the UDP-Glucuronosyltransferase Isoforms responsible for the metabolism of flavonoids in intact caco-2 TC7 cells using siRNA
    • Liu, X.; Tam, V. H.; and Hu, M. (2007). Disposition of flavonoids via enteric recycling: Determination of the UDP-Glucuronosyltransferase Isoforms responsible for the metabolism of flavonoids in intact caco-2 TC7 cells using siRNA. Molecular Pharmaceutics, 4, 873-882.
    • (2007) Molecular Pharmaceutics , vol.4 , pp. 873-882
    • Liu, X.1    Tam, V.H.2    Hu, M.3
  • 138
    • 0034737452 scopus 로고    scopus 로고
    • Transport mechanism and metabolism of olive oil hydroxytyrosol in Caco-2 cells
    • Manna, C.; Galletti, P.; Maisto, G.; Cucciolla, V.; D'Angelo, S.; and Zappia, V. (2000). Transport mechanism and metabolism of olive oil hydroxytyrosol in Caco-2 cells. FEBS Letters, 470, 341-344.
    • (2000) FEBS Letters , vol.470 , pp. 341-344
    • Manna, C.1    Galletti, P.2    Maisto, G.3    Cucciolla, V.4    D'Angelo, S.5    Zappia, V.6
  • 140
    • 8444226748 scopus 로고    scopus 로고
    • Uptake of quercetin and quercetin 3glucoside from whole onion and apple peel extracts by Caco-2 cell monolayers
    • Boyer, J.; Brown, D.; and Rui, H.L. (2004). Uptake of quercetin and quercetin 3glucoside from whole onion and apple peel extracts by Caco-2 cell monolayers. Journal of Agricultural and Food Chemistry, 52, 7172-7179.
    • (2004) Journal of Agricultural and Food Chemistry , vol.52 , pp. 7172-7179
    • Boyer, J.1    Brown, D.2    Rui, H.L.3
  • 141
    • 0033846534 scopus 로고    scopus 로고
    • Cellular uptake of dietary flavonoid quercetin 4'-beta -glucoside by sodium-dependent glucose transporter SGLT1
    • Walgren, R. A.; Lin, J.-T.; Kinne, R. K. H.; and Walle, T. (2000). Cellular uptake of dietary flavonoid quercetin 4'-beta -glucoside by sodium-dependent glucose transporter SGLT1. Journal of Pharmacology and Experimental Therapeutics, 294, 837-843.
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.294 , pp. 837-843
    • Walgren, R.A.1    Lin, J.-T.2    Kinne, R.K.H.3    Walle, T.4
  • 142
    • 34250336160 scopus 로고    scopus 로고
    • Interaction of flavonoids and intestinal facilitated glucose transporters
    • Chen, C. H.; Hsu, H. J.; Huang, Y. J.; and Lin, C. J. (2007). Interaction of flavonoids and intestinal facilitated glucose transporters. Planta Medica, 73, 348-354.
    • (2007) Planta Medica , vol.73 , pp. 348-354
    • Chen, C.H.1    Hsu, H.J.2    Huang, Y.J.3    Lin, C.J.4
  • 143
    • 33748429568 scopus 로고    scopus 로고
    • Metabolism of quercetin and rutin by the pig caecal microflora prepared by freeze-preservation
    • Keppler, K.; Hein, E. M.; and Humpf, H. U. (2006). Metabolism of quercetin and rutin by the pig caecal microflora prepared by freeze-preservation. Molecular Nutrition and Food Research, 50, 686-695.
    • (2006) Molecular Nutrition and Food Research , vol.50 , pp. 686-695
    • Keppler, K.1    Hein, E.M.2    Humpf, H.U.3
  • 144
    • 13844296392 scopus 로고    scopus 로고
    • Human fecal water content of phenolics: The extent of colonic exposure to aromatic compounds
    • Jenner, A. M.; Rafter, J.; and Halliwell, B. (2005). Human fecal water content of phenolics: The extent of colonic exposure to aromatic compounds. Free Radical Biology and Medicine, 38, 763-772.
    • (2005) Free Radical Biology and Medicine , vol.38 , pp. 763-772
    • Jenner, A.M.1    Rafter, J.2    Halliwell, B.3
  • 146
    • 0034031915 scopus 로고    scopus 로고
    • Hippuric acid as a major excretion product associated with black tea consumption
    • Clifford, M. N.; Copeland, E. L.; Bloxsidge, J. P.; and Mitchell, L. A. (2000). Hippuric acid as a major excretion product associated with black tea consumption. Xenobiotica, 30, 317-326.
    • (2000) Xenobiotica , vol.30 , pp. 317-326
    • Clifford, M.N.1    Copeland, E.L.2    Bloxsidge, J.P.3    Mitchell, L.A.4
  • 147
    • 13844280421 scopus 로고    scopus 로고
    • Consumption of both black tea and green tea results in an increase in the excretion of hippuric acid into urine
    • Mulder, T. P.; Rietveld, A. G.; and van Amelsvoort, J. M. (2005). Consumption of both black tea and green tea results in an increase in the excretion of hippuric acid into urine. American Journal of Clinical Nutrition, 81, 256S-260S.
    • (2005) American Journal of Clinical Nutrition , vol.81
    • Mulder, T.P.1    Rietveld, A.G.2    Amelsvoort van, J.M.3
  • 149
    • 33845269813 scopus 로고    scopus 로고
    • Identification of glutathione-related quercetin metabolites in humans
    • Hong, Y. J.; and Mitchell, A. E. (2006). Identification of glutathione-related quercetin metabolites in humans. Chemical Research in Toxicology, 19, 1525-1532.
    • (2006) Chemical Research in Toxicology , vol.19 , pp. 1525-1532
    • Hong, Y.J.1    Mitchell, A.E.2
  • 150
    • 34447636817 scopus 로고    scopus 로고
    • Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications
    • Russell, W. R.; Labat, A.; Scobbie, L.; and Duncan, S. H. (2007). Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications. Molecular Nutrition and Food Research, 51, 726-731.
    • (2007) Molecular Nutrition and Food Research , vol.51 , pp. 726-731
    • Russell, W.R.1    Labat, A.2    Scobbie, L.3    Duncan, S.H.4
  • 152
    • 0038653491 scopus 로고    scopus 로고
    • Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats
    • Gonthier, M.-P.; Verny, M.-A.; Besson, C.; Remesy, C.; and Scalbert, A. (2003). Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats. Journal of Nutrition, 133, 1853-1859.
    • (2003) Journal of Nutrition , vol.133 , pp. 1853-1859
    • Gonthier, M.-P.1    Verny, M.-A.2    Besson, C.3    Remesy, C.4    Scalbert, A.5
  • 155
    • 36448962327 scopus 로고    scopus 로고
    • Determination of phenolic composition and antioxidant capacity of blood orange juices obtained from cvs. Moro and Sanguinello (Citrus sinensis (L.) Osbeck) grown in Turkey
    • Kelebek, H.; Canbas, A.; and Selli, S. (2008). Determination of phenolic composition and antioxidant capacity of blood orange juices obtained from cvs. Moro and Sanguinello (Citrus sinensis (L.) Osbeck) grown in Turkey. Food Chemistry, 107, 1710-1716.
    • (2008) Food Chemistry , vol.107 , pp. 1710-1716
    • Kelebek, H.1    Canbas, A.2    Selli, S.3
  • 157
    • 2342588813 scopus 로고    scopus 로고
    • Intestinal absorption of p-coumaric and gallic acids in rats after oral administration
    • Konishi, Y.; Hitomi, Y.; and Yoshioka, E. (2004). Intestinal absorption of p-coumaric and gallic acids in rats after oral administration. Journal of Agricultural and Food Chemistry, 52, 2527-2532.
    • (2004) Journal of Agricultural and Food Chemistry , vol.52 , pp. 2527-2532
    • Konishi, Y.1    Hitomi, Y.2    Yoshioka, E.3
  • 158
    • 0036170655 scopus 로고    scopus 로고
    • Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans
    • DuPont, M. S.; Bennett, R. N.; Mellon, F. A.; and Williamson, G. (2002). Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans. Journal of Nutrition, 132, 172-175.
    • (2002) Journal of Nutrition , vol.132 , pp. 172-175
    • DuPont, M.S.1    Bennett, R.N.2    Mellon, F.A.3    Williamson, G.4
  • 160
    • 17244372649 scopus 로고    scopus 로고
    • Analysis of Anthocyanins in Rat Intestinal Contents-Impact of Anthocyanin Chemical Structure on Fecal Excretion
    • He, J.; Magnuson, B. A.; and Giusti, M. M. (2005). Analysis of Anthocyanins in Rat Intestinal Contents-Impact of Anthocyanin Chemical Structure on Fecal Excretion. Journal of Agricultural and Food Chemistry, 53, 2859-2866.
    • (2005) Journal of Agricultural and Food Chemistry , vol.53 , pp. 2859-2866
    • He, J.1    Magnuson, B.A.2    Giusti, M.M.3
  • 162
    • 34547485050 scopus 로고    scopus 로고
    • Metabolism of dietary soy isoflavones to equol by human intestinal microflora -implications for health
    • Yuan, J. P.; Wang, J. H.; and Liu, X. (2007). Metabolism of dietary soy isoflavones to equol by human intestinal microflora -implications for health. Molecular Nutrition and Food Research, 51, 765-781.
    • (2007) Molecular Nutrition and Food Research , vol.51 , pp. 765-781
    • Yuan, J.P.1    Wang, J.H.2    Liu, X.3
  • 163
    • 2342643438 scopus 로고    scopus 로고
    • Influence of soya-based infant formula consumption on isoflavone and gut microflora metabolite concentrations in urine and on faecal microflora composition and metabolic activity in infants and children
    • Hoey, L.; Rowland, I. R.; Lloyd, A.S.; Clarke, D. B.; and Wiseman, H. (2004). Influence of soya-based infant formula consumption on isoflavone and gut microflora metabolite concentrations in urine and on faecal microflora composition and metabolic activity in infants and children. British Journal of Nutrition, 91, 607-616.
    • (2004) British Journal of Nutrition , vol.91 , pp. 607-616
    • Hoey, L.1    Rowland, I.R.2    Lloyd, A.S.3    Clarke, D.B.4    Wiseman, H.5
  • 164
    • 33749507179 scopus 로고    scopus 로고
    • Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota
    • Lee, H. C.; Jenner, A. M.; Low, C. S.; and Lee, Y. K. (2006). Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota. Research in Microbiology, 157, 876-884.
    • (2006) Research in Microbiology , vol.157 , pp. 876-884
    • Lee, H.C.1    Jenner, A.M.2    Low, C.S.3    Lee, Y.K.4
  • 166
    • 0034333424 scopus 로고    scopus 로고
    • Biotransformation of the isoflavonoids biochanin A, formononetin, and glycitein by Eubacterium limosum
    • Hor-Gil Hur, F. R. (2000). Biotransformation of the isoflavonoids biochanin A, formononetin, and glycitein by Eubacterium limosum. FEMS Microbiology Letters, 192, 21-25.
    • (2000) FEMS Microbiology Letters , vol.192 , pp. 21-25
    • Hor-Gil Hur, F.R.1
  • 167
    • 41249083356 scopus 로고    scopus 로고
    • Microbial metabolism of catechin stereoisomers by human faecal microbiota: Comparison of targeted analysis and a non-targeted metabolomics method
    • Aura, A.-M.; Mattila, I.; Seppänen-Laakso, T.; Miettinen, J.; Oksman-Caldentey, K.M.; and Oresic, M. (2008). Microbial metabolism of catechin stereoisomers by human faecal microbiota: Comparison of targeted analysis and a non-targeted metabolomics method. Phytochemistry Letters, 1, 18-22.
    • (2008) Phytochemistry Letters , vol.1 , pp. 18-22
    • Aura, A.-M.1    Mattila, I.2    Seppänen-Laakso, T.3    Miettinen, J.4    Oksman-Caldentey, K.M.5    Oresic, M.6
  • 168
    • 0031009218 scopus 로고    scopus 로고
    • Biotransformation of (-)epicatechin 3-O-gallate by human intestinal bacteria
    • Meselhy, M. R.; Nakamura, N.; and Hattori, M. (1997). Biotransformation of (-)epicatechin 3-O-gallate by human intestinal bacteria. Chemical and Pharmaceutical Bulletin, 45, 888-893.
    • (1997) Chemical and Pharmaceutical Bulletin , vol.45 , pp. 888-893
    • Meselhy, M.R.1    Nakamura, N.2    Hattori, M.3
  • 169
    • 0035209197 scopus 로고    scopus 로고
    • The Heterocyclic Ring Fission and Dehydroxylation of Catechins and Related Compounds by Eubacterium sp. Strain SDG-2, a Human Intestinal Bacterium
    • Wang, L.-Q.; Meselhy, M.R.; Li, Y.; Nakamura, N.; Min, B.-S.; Qin, G.-W.; and Hattori, M. (2001). The Heterocyclic Ring Fission and Dehydroxylation of Catechins and Related Compounds by Eubacterium sp. Strain SDG-2, a Human Intestinal Bacterium. Chemical and Pharmaceutical Bulletin, 49, 1640-1643.
    • (2001) Chemical and Pharmaceutical Bulletin , vol.49 , pp. 1640-1643
    • Wang, L.-Q.1    Meselhy, M.R.2    Li, Y.3    Nakamura, N.4    Min, B.-S.5    Qin, G.-W.6    Hattori, M.7
  • 171
    • 9944239203 scopus 로고    scopus 로고
    • The pig caecum model: A suitable tool to study the intestinal metabolism of flavonoids
    • Labib, S.; Erb, A.; Kraus, M.; Wickert, T.; and Richling, E. (2004). The pig caecum model: A suitable tool to study the intestinal metabolism of flavonoids. Molecular Nutrition and Food Research, 48, 326-332.
    • (2004) Molecular Nutrition and Food Research , vol.48 , pp. 326-332
    • Labib, S.1    Erb, A.2    Kraus, M.3    Wickert, T.4    Richling, E.5
  • 172
    • 31544445752 scopus 로고    scopus 로고
    • Of the major phenolic acids formed during human microbial fermentation of tea, citrus, and soy flavonoid supplements, only 3,4-dihydroxyphenylacetic acid has antiproliferative activity
    • Gao, K.; Xu, A. L.; Krul, C.; Venema, K.; Liu, Y.; Niu, Y. T.; Lu, J. X.; Bensoussan, L.; Seeram, N. P.; Heber, D.; and Henning, S. M. (2006). Of the major phenolic acids formed during human microbial fermentation of tea, citrus, and soy flavonoid supplements, only 3,4-dihydroxyphenylacetic acid has antiproliferative activity. Journal of Nutrition, 136, 52-57.
    • (2006) Journal of Nutrition , vol.136 , pp. 52-57
    • Gao, K.1    Xu, A.L.2    Krul, C.3    Venema, K.4    Liu, Y.5    Niu, Y.T.6    Lu, J.X.7    Bensoussan, L.8    Seeram, N.P.9    Heber, D.10    Henning, S.M.11
  • 174
  • 175
    • 0033745131 scopus 로고    scopus 로고
    • Polymeric Proanthocyanidins Are Catabolized by Human Colonic Microflora into Low-Molecular-Weight Phenolic Acids
    • Deprez, S.; Brezillon, C.; Rabot, S.; Philippe, C.; Mila, I.; Lapierre, C.; and Scalbert, A. (2000). Polymeric Proanthocyanidins Are Catabolized by Human Colonic Microflora into Low-Molecular-Weight Phenolic Acids. Journal of Nutrition, 130, 2733-2738.
    • (2000) Journal of Nutrition , vol.130 , pp. 2733-2738
    • Deprez, S.1    Brezillon, C.2    Rabot, S.3    Philippe, C.4    Mila, I.5    Lapierre, C.6    Scalbert, A.7
  • 176
    • 0033000640 scopus 로고    scopus 로고
    • Anaerobic transformation of quercetin-3-glucoside by bacteria from the human intestinal tract
    • Schneider, H.; Schwiertz, A.; Collins, M. D.;and Blaut, M. (1999). Anaerobic transformation of quercetin-3-glucoside by bacteria from the human intestinal tract. Archives of Microbiology, 171, 81-91.
    • (1999) Archives of Microbiology , vol.171 , pp. 81-91
    • Schneider, H.1    Schwiertz, A.2    Collins M.D.3    and Blaut, M.4
  • 178
    • 0001699545 scopus 로고    scopus 로고
    • Degradation of flavonoid glycosides and aglycones during in vitro fermentation with human faecal flora
    • Justesen, U.; Arrigoni, E.; Larsen, B. R.; and Amado, R. (2000). Degradation of flavonoid glycosides and aglycones during in vitro fermentation with human faecal flora. Lebensmittel-Wissenschaft und-Technologie, 33, 424-430.
    • (2000) Lebensmittel-Wissenschaft und-Technologie , vol.33 , pp. 424-430
    • Justesen, U.1    Arrigoni, E.2    Larsen, B.R.3    Amado, R.4
  • 181
    • 0034528031 scopus 로고    scopus 로고
    • Degradation of quercetin-3-glucoside in gnotobiotic rats associated with human intestinal bacteria
    • Schneider, H.; Simmering, R.; Hartmann, L.; Pforte, H.; and Blaut, M. (2000). Degradation of quercetin-3-glucoside in gnotobiotic rats associated with human intestinal bacteria. Journal of Applied Microbiology, 89, 1027-1037.
    • (2000) Journal of Applied Microbiology , vol.89 , pp. 1027-1037
    • Schneider, H.1    Simmering, R.2    Hartmann, L.3    Pforte, H.4    Blaut, M.5
  • 182
    • 0033978259 scopus 로고    scopus 로고
    • Anaerobic degradation of flavonoids by Eubacterium ramulus
    • Schneider, H.; and Blaut, M. (2000). Anaerobic degradation of flavonoids by Eubacterium ramulus. Archives of Microbiology, 173, 71-75.
    • (2000) Archives of Microbiology , vol.173 , pp. 71-75
    • Schneider, H.1    Blaut, M.2
  • 183
    • 41849099278 scopus 로고    scopus 로고
    • Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by fluorescence in situ hybridization (FISH)
    • Hein, E. M.; Rose, K.; Van't Slot, G.; Friedrich, A. W.; and Humpf, H. U. (2008). Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by fluorescence in situ hybridization (FISH). Journal of Agricultural and Food Chemistry, 56, 2281-2290.
    • (2008) Journal of Agricultural and Food Chemistry , vol.56 , pp. 2281-2290
    • Hein, E.M.1    Rose, K.2    Van't Slot, G.3    Friedrich, A.W.4    Humpf, H.U.5
  • 185
    • 37549031270 scopus 로고    scopus 로고
    • Pharmacokinetics and bioavailability of the bioflavonoid biochanin A: Effects of quercetin and EGCG on biochanin A disposition in rats
    • Moon, Y. J.; and Morris, M. E. (2007). Pharmacokinetics and bioavailability of the bioflavonoid biochanin A: Effects of quercetin and EGCG on biochanin A disposition in rats. Molecular Pharmaceutics, 4, 865-872.
    • (2007) Molecular Pharmaceutics , vol.4 , pp. 865-872
    • Moon, Y.J.1    Morris, M.E.2
  • 187
    • 1042267902 scopus 로고    scopus 로고
    • LC-MS identification of anthocyanins in boysenberry extract and anthocyanin metabolites in human urine following dosing
    • Cooney, J. M.; Jensen, D. J.; and McGhie, T. K. (2004). LC-MS identification of anthocyanins in boysenberry extract and anthocyanin metabolites in human urine following dosing. Journal of the Science of Food and Agriculture, 84, 237-245.
    • (2004) Journal of the Science of Food and Agriculture , vol.84 , pp. 237-245
    • Cooney, J.M.1    Jensen, D.J.2    McGhie, T.K.3
  • 188
    • 26444585579 scopus 로고    scopus 로고
    • Aglycones and sugar moieties alter anthocyanin absorption and metabolism after berry consumption in weanling pigs
    • Wu, X.; Pittman, H. E., III; McKay, S.; and Prior, R. L. (2005). Aglycones and sugar moieties alter anthocyanin absorption and metabolism after berry consumption in weanling pigs. Journal of Nutrition, 135, 2417-2424.
    • (2005) Journal of Nutrition , vol.135 , pp. 2417-2424
    • Wu, X.1    Pittman, H.E.2    III McKay, S.3    Prior, R.L.4
  • 189
    • 4744365198 scopus 로고    scopus 로고
    • Pelargonidin is absorbed and metabolized differently than cyanidin after marionberry consumption in pigs
    • Wu, X.; Pittman, H. E., III; and Prior, R. L. (2004). Pelargonidin is absorbed and metabolized differently than cyanidin after marionberry consumption in pigs. Journal of Nutrition, 134, 2603-2610.
    • (2004) Journal of Nutrition , vol.134 , pp. 2603-2610
    • Wu, X.1    Pittman, H.E.2    III Prior, R.L.3
  • 190
    • 0035543069 scopus 로고    scopus 로고
    • Absorption and urinary excretion of (-)-epicatechin after administration of different levels of cocoa powder or (-)-epicatechin in rats
    • Baba, S.; Osakabe, N.; Natsume, M.; Muto, Y.; Takizawa, T.; and Terao, J. (2001). Absorption and urinary excretion of (-)-epicatechin after administration of different levels of cocoa powder or (-)-epicatechin in rats. Journal of Agricultural and Food Chemistry, 49, 6050-6056.
    • (2001) Journal of Agricultural and Food Chemistry , vol.49 , pp. 6050-6056
    • Baba, S.1    Osakabe, N.2    Natsume, M.3    Muto, Y.4    Takizawa, T.5    Terao, J.6
  • 194
    • 0036667454 scopus 로고    scopus 로고
    • Identification and Characterization of Methylated and Ring-Fission Metabolites of Tea Catechins Formed in Humans, Mice, and Rats
    • Meng, X.; Sang, S.; Zhu, N.; Lu, H.; Sheng, S.; Lee, M. J.; Ho, C. T.; and Yang, C. S. (2002). Identification and Characterization of Methylated and Ring-Fission Metabolites of Tea Catechins Formed in Humans, Mice, and Rats. Chemical Research in Toxicology, 15, 1042-1050.
    • (2002) Chemical Research in Toxicology , vol.15 , pp. 1042-1050
    • Meng, X.1    Sang, S.2    Zhu, N.3    Lu, H.4    Sheng, S.5    Lee, M.J.6    Ho, C.T.7    Yang, C.S.8
  • 196
    • 0037376885 scopus 로고    scopus 로고
    • Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: differences between human and rat
    • Natsume, M.; Osakabe, N.; Oyama, M.; Sasaki, M.; Baba, S.; Nakamura, Y.; Osawa, T.; and Terao, J. (2003). Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: differences between human and rat. Free Radical Biology and Medicine, 34, 840-849.
    • (2003) Free Radical Biology and Medicine , vol.34 , pp. 840-849
    • Natsume, M.1    Osakabe, N.2    Oyama, M.3    Sasaki, M.4    Baba, S.5    Nakamura, Y.6    Osawa, T.7    Terao, J.8
  • 203
    • 0036300211 scopus 로고    scopus 로고
    • Absorption and metabolism of anthocyanins in elderly women after consumption of elderberry or blueberry
    • Wu, X.; Cao, G.; and Prior, R. L. (2002). Absorption and metabolism of anthocyanins in elderly women after consumption of elderberry or blueberry. Journal of Nutrition, 132, 1865-1871.
    • (2002) Journal of Nutrition , vol.132 , pp. 1865-1871
    • Wu, X.1    Cao, G.2    Prior, R.L.3
  • 204
    • 33244497325 scopus 로고    scopus 로고
    • Apple procyanidin oligomers absorption in rats after oral administration: Analysis of procyanidins in plasma using the porter method and high-performance liquid chromatography/tandem mass spectrometry
    • Shoji, T.; Masumoto, S.; Moriichi, N.; Akiyama, H.; Kanda, T.; Ohtake, Y.; and Goda, Y. (2006). Apple procyanidin oligomers absorption in rats after oral administration: Analysis of procyanidins in plasma using the porter method and high-performance liquid chromatography/tandem mass spectrometry. Journal of Agricultural and Food Chemistry, 54, 884-892.
    • (2006) Journal of Agricultural and Food Chemistry , vol.54 , pp. 884-892
    • Shoji, T.1    Masumoto, S.2    Moriichi, N.3    Akiyama, H.4    Kanda, T.5    Ohtake, Y.6    Goda, Y.7
  • 206
    • 0042031054 scopus 로고    scopus 로고
    • Bioavailability of dietary doses of H-3-labelled tea antioxidants (+)-catechin and (-)-epicatechin in rat
    • Catterall, F.; King, L. J.; Clifford, M. N.; and Ioannides, C. (2003). Bioavailability of dietary doses of H-3-labelled tea antioxidants (+)-catechin and (-)-epicatechin in rat. Xenobiotica, 33, 743-753.
    • (2003) Xenobiotica , vol.33 , pp. 743-753
    • Catterall, F.1    King, L.J.2    Clifford, M.N.3    Ioannides, C.4
  • 208
    • 7244236364 scopus 로고    scopus 로고
    • Identification of urinary metabolites of the red clover isoflavones formononetin and biochanin A in human subjects
    • Heinonen, S. M.; Wahala, K.; and Adlercreutz, H. (2004). Identification of urinary metabolites of the red clover isoflavones formononetin and biochanin A in human subjects. Journal of Agricultural and Food Chemistry, 52, 6802-6809.
    • (2004) Journal of Agricultural and Food Chemistry , vol.52 , pp. 6802-6809
    • Heinonen, S.M.1    Wahala, K.2    Adlercreutz, H.3
  • 212
    • 80051831913 scopus 로고    scopus 로고
    • Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream
    • Mullen, W.; Edwards, C. A.; Serafini, M.; and Crozier, A. (2008). Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream. Journal of Agricultural and Food Chemistry, 56, 713-719.
    • (2008) Journal of Agricultural and Food Chemistry , vol.56 , pp. 713-719
    • Mullen, W.1    Edwards, C.A.2    Serafini, M.3    Crozier, A.4
  • 213
  • 214
    • 0036803797 scopus 로고    scopus 로고
    • Albumin, steroid hormones and the origin of vertebrates
    • Baker, M. E. (2002). Albumin, steroid hormones and the origin of vertebrates. Journal of Endocrinology, 175, 121-127.
    • (2002) Journal of Endocrinology , vol.175 , pp. 121-127
    • Baker, M.E.1
  • 215
    • 0030853262 scopus 로고    scopus 로고
    • Environmental pollution, pesticides, and the prevention of cancer: Misconceptions
    • Ames, B. N.; and Gold, L.S. (1997). Environmental pollution, pesticides, and the prevention of cancer: Misconceptions. Faseb Journal, 11, 1041-1052.
    • (1997) Faseb Journal , vol.11 , pp. 1041-1052
    • Ames, B.N.1    Gold, L.S.2
  • 217
    • 4043130207 scopus 로고    scopus 로고
    • Properties of quercetin conjugates: Modulation of LDL oxidation and binding to human serum albumin
    • Janisch, K. M.; Williamson, G.; Needs, P.; and Plumb, G. W. (2004). Properties of quercetin conjugates: Modulation of LDL oxidation and binding to human serum albumin. Free Radical Research, 38, 877-884.
    • (2004) Free Radical Research , vol.38 , pp. 877-884
    • Janisch, K.M.1    Williamson, G.2    Needs, P.3    Plumb, G.W.4
  • 218
    • 9244243170 scopus 로고    scopus 로고
    • Spectrophotometric and kinetic studies on the binding of the bioflavonoid quercetin to bovine serum albumin
    • Kitson, T. M. (2004). Spectrophotometric and kinetic studies on the binding of the bioflavonoid quercetin to bovine serum albumin. Bioscience Biotechnology and Biochemistry, 68, 2165-2170.
    • (2004) Bioscience Biotechnology and Biochemistry , vol.68 , pp. 2165-2170
    • Kitson, T.M.1
  • 219
  • 220
    • 11844253806 scopus 로고    scopus 로고
    • Flavonoid-serum albumin complexation: determination of binding constants and binding sites by fluorescence spectroscopy
    • Dufour, C.;and Dangles, O. (2005). Flavonoid-serum albumin complexation: determination of binding constants and binding sites by fluorescence spectroscopy. Biochimica et Biophysica Acta-General Subjects, 1721, 164-173.
    • (2005) Biochimica et Biophysica Acta-General Subjects , vol.1721 , pp. 164-173
    • Dufour C.1    and Dangles, O.2
  • 223
    • 0141849078 scopus 로고    scopus 로고
    • Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)epigallocatechin-3-gallate and its methyl metabolites
    • Hong, J.; Lambert, J. D.; Lee, S. H.; Sinko, P. J.; and Yang, C. S. (2003). Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)epigallocatechin-3-gallate and its methyl metabolites. Biochemical and Biophysical Research Communications, 310, 222-227.
    • (2003) Biochemical and Biophysical Research Communications , vol.310 , pp. 222-227
    • Hong, J.1    Lambert, J.D.2    Lee, S.H.3    Sinko, P.J.4    Yang, C.S.5
  • 224
    • 0029983527 scopus 로고    scopus 로고
    • Properties of an immortalised vascular endothelial glioma cell co-culture model of the blood-brain barrier
    • Hurst, R. D.; and Fritz, I. B. (1996). Properties of an immortalised vascular endothelial glioma cell co-culture model of the blood-brain barrier. Journal of Cellular Physiology, 167, 81-88.
    • (1996) Journal of Cellular Physiology , vol.167 , pp. 81-88
    • Hurst, R.D.1    Fritz, I.B.2
  • 228
    • 0035046916 scopus 로고    scopus 로고
    • Effect of plasma metabolites of (+)-catechin and quercetin on monocyte adhesion to human aortic endothelial cells
    • Koga, T.; and Meydani, M. (2001). Effect of plasma metabolites of (+)-catechin and quercetin on monocyte adhesion to human aortic endothelial cells. American Journal of Clinical Nutrition, 73, 941-948.
    • (2001) American Journal of Clinical Nutrition , vol.73 , pp. 941-948
    • Koga, T.1    Meydani, M.2
  • 229
    • 0036190435 scopus 로고    scopus 로고
    • Comparison of antioxidative capacities and inhibitory effects on cholesterol biosynthesis of quercetin and potential metabolites
    • Gläßer, G.; Graefe, E. U.; Struck, F.; Veit, M.; and Gebhardt, R. (2002). Comparison of antioxidative capacities and inhibitory effects on cholesterol biosynthesis of quercetin and potential metabolites. Phytomedicine, 9, 33-40.
    • (2002) Phytomedicine , vol.9 , pp. 33-40
    • Gläßer, G.1    Graefe, E.U.2    Struck, F.3    Veit, M.4    Gebhardt, R.5
  • 230
    • 0035183661 scopus 로고    scopus 로고
    • Inhibitory effect of a quercetin metabolite, quercetin 3-O-beta-D-Glucuronide, on lipid peroxidation in liposomal membranes
    • Shirai, M.; Moon, J. H.; Tsushida, T.; and Terao, J. (2001). Inhibitory effect of a quercetin metabolite, quercetin 3-O-beta-D-Glucuronide, on lipid peroxidation in liposomal membranes. Journal of Agricultural and Food Chemistry, 49, 5602-5608.
    • (2001) Journal of Agricultural and Food Chemistry , vol.49 , pp. 5602-5608
    • Shirai, M.1    Moon, J.H.2    Tsushida, T.3    Terao, J.4
  • 231
    • 0036561383 scopus 로고    scopus 로고
    • Effect of quercetin and its conjugated metabolite on the hydrogen peroxide-induced intracellular production of reactive oxygen species in mouse fibroblasts
    • Shirai, M.; Yamanishi, R.; Moon, J. H.; Murota, K.; and Terao, J. (2002). Effect of quercetin and its conjugated metabolite on the hydrogen peroxide-induced intracellular production of reactive oxygen species in mouse fibroblasts. Bioscience Biotechnology and Biochemistry, 66, 1015-1021.
    • (2002) Bioscience Biotechnology and Biochemistry , vol.66 , pp. 1015-1021
    • Shirai, M.1    Yamanishi, R.2    Moon, J.H.3    Murota, K.4    Terao, J.5
  • 234
    • 45849134176 scopus 로고    scopus 로고
    • Glucuronidated metabolites of the flavonoid quercetin do not auto-oxidise, do not generate free radicals and do not decrease nitric oxide bioavailability
    • Lodi, F.; Jimenez, R.; Menendez, C.; Needs, P. W.; Duarte, J.; and Perez-Vizcaino, F. (2008). Glucuronidated metabolites of the flavonoid quercetin do not auto-oxidise, do not generate free radicals and do not decrease nitric oxide bioavailability. Planta Medica, 74, 741-746.
    • (2008) Planta Medica , vol.74 , pp. 741-746
    • Lodi, F.1    Jimenez, R.2    Menendez, C.3    Needs, P.W.4    Duarte, J.5    Perez-Vizcaino, F.6
  • 236
    • 0041816456 scopus 로고    scopus 로고
    • Modulation of pro-survival Akt/Protein Kinase B and ERK1/2 signaling cascades by quercetin and Its in vivo metabolites underlie their action on neuronal viability
    • Spencer, J. P. E.; Rice-Evans, C.; and Williams, R. J. (2003). Modulation of pro-survival Akt/Protein Kinase B and ERK1/2 signaling cascades by quercetin and Its in vivo metabolites underlie their action on neuronal viability. Journal of Biological Chemistry, 278, 34783-34793.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 34783-34793
    • Spencer, J.P.E.1    Rice-Evans, C.2    Williams, R.J.3
  • 237
    • 0034672514 scopus 로고    scopus 로고
    • Conjugation position of quercetin glucuronides and effect on biological activity
    • Day, A.J.; Bao, Y.; Morgan, M. R. A.; and Williamson, G. (2000). Conjugation position of quercetin glucuronides and effect on biological activity. Free Radical Biology and Medicine, 29, 1234-1243.
    • (2000) Free Radical Biology and Medicine , vol.29 , pp. 1234-1243
    • Day, A.J.1    Bao, Y.2    Morgan, M.R.A.3    Williamson, G.4
  • 238
    • 0036813344 scopus 로고    scopus 로고
    • Quercetin glucuronides inhibited 2-aminofluorene acetylation in human acute myeloid HL-60 leukemia cells
    • Kuo, H. M.; Ho, H. J.; Chao, P. D. L.; and Chung, J. G. (2002). Quercetin glucuronides inhibited 2-aminofluorene acetylation in human acute myeloid HL-60 leukemia cells. Phytomedicine, 9, 625-631.
    • (2002) Phytomedicine , vol.9 , pp. 625-631
    • Kuo, H.M.1    Ho, H.J.2    Chao, P.D.L.3    Chung, J.G.4
  • 239
    • 4544337496 scopus 로고    scopus 로고
    • Protective Effects of Quercetin and Its Metabolites on H2O2-Induced Chromosomal Damage to WIL2-NS Cells
    • Saito, A.; Sugisawa, A.; Umegaki, K.; and Sunagawa, H. (2004). Protective Effects of Quercetin and Its Metabolites on H2O2-Induced Chromosomal Damage to WIL2-NS Cells. Bioscience, Biotechnology, and Biochemistry, 68, 271-276.
    • (2004) Bioscience, Biotechnology, and Biochemistry , vol.68 , pp. 271-276
    • Saito, A.1    Sugisawa, A.2    Umegaki, K.3    Sunagawa, H.4
  • 240
    • 0033899959 scopus 로고    scopus 로고
    • Inhibitory effect of disodium qurecetin-7, 4'-disulfate on aggregation of pig platelets induced by thrombin and its mechanism
    • Liu, W.; and Liang, N. (2000). Inhibitory effect of disodium qurecetin-7, 4'-disulfate on aggregation of pig platelets induced by thrombin and its mechanism. Acta Pharmacologica Sinica, 21, 737-741.
    • (2000) Acta Pharmacologica Sinica , vol.21 , pp. 737-741
    • Liu, W.1    Liang, N.2
  • 241
    • 0344255791 scopus 로고    scopus 로고
    • Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock
    • Fang, S.-H.; Hou, Y.-C.; Chang, W.-C.; Hsiu, S.-L.; Lee Chao, P.-D.; and Chiang, B.-L. (2003). Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock. Life Sciences, 74, 743-756.
    • (2003) Life Sciences , vol.74 , pp. 743-756
    • Fang, S.-H.1    Hou, Y.-C.2    Chang, W.-C.3    Hsiu, S.-L.4    Lee Chao, P.-D.5    Chiang, B.-L.6
  • 242
    • 24144458922 scopus 로고    scopus 로고
    • Morin sulphates/glucuronides enhance macrophage function in microgravity culture system
    • Hsieh, C.-L.; Chao, P. D. L.; and Fang, S. H. (2005). Morin sulphates/glucuronides enhance macrophage function in microgravity culture system. European Journal of Clinical Investigation, 35, 591-596.
    • (2005) European Journal of Clinical Investigation , vol.35 , pp. 591-596
    • Hsieh, C.-L.1    Chao, P.D.L.2    Fang, S.H.3
  • 244
    • 0030583290 scopus 로고    scopus 로고
    • Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes
    • Tseng, T.-H.; Wang, C.-J.; Kao, E.-S.; and Chu, h.-Y. (1996). Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes. Chemico-Biological Interactions, 101, 137-148.
    • (1996) Chemico-Biological Interactions , vol.101 , pp. 137-148
    • Tseng, T.-H.1    Wang, C.-J.2    Kao, E.-S.3    Chu, H.-Y.4
  • 245
    • 0034256987 scopus 로고    scopus 로고
    • Induction of apoptosis by Hibiscus protocatechuic acid in human leukemia cells via reduction of retinoblastoma (RB) phosphorylation and Bcl-2 expression
    • Tseng, T.-H.; Kao, T.-W.; Chu, C.-Y.; Chou, F.-P.; Lin, W.-L.; and Wang, C.-J. (2000). Induction of apoptosis by Hibiscus protocatechuic acid in human leukemia cells via reduction of retinoblastoma (RB) phosphorylation and Bcl-2 expression. Biochemical Pharmacology, 60, 307-315.
    • (2000) Biochemical Pharmacology , vol.60 , pp. 307-315
    • Tseng, T.-H.1    Kao, T.-W.2    Chu, C.-Y.3    Chou, F.-P.4    Lin, W.-L.5    Wang, C.-J.6
  • 246
    • 0036230951 scopus 로고    scopus 로고
    • In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity
    • Liu, C.-L.; Wang, J.-M.; Chu, C.-Y.; Cheng, M.-T.; and Tseng, T.-H. (2002). In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity. Food and Chemical Toxicology, 40, 635-641.
    • (2002) Food and Chemical Toxicology , vol.40 , pp. 635-641
    • Liu, C.-L.1    Wang, J.-M.2    Chu, C.-Y.3    Cheng, M.-T.4    Tseng, T.-H.5
  • 249
    • 0035500851 scopus 로고    scopus 로고
    • Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts
    • Spencer, J. P. E.; Schroeter, H.; Crossthwaithe, A. J.; Kuhnle, G.; Williams, R. J.; and Rice-Evans, C. (2001). Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts. Free Radical Biology and Medicine, 31, 1139-1146.
    • (2001) Free Radical Biology and Medicine , vol.31 , pp. 1139-1146
    • Spencer, J.P.E.1    Schroeter, H.2    Crossthwaithe, A.J.3    Kuhnle, G.4    Williams, R.J.5    Rice-Evans, C.6
  • 250
    • 0035868353 scopus 로고    scopus 로고
    • Epicatechin and its in vivo metabolite, 3 '-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation
    • Spencer, J. P. E.; Schroeter, H.; Kuhnle, G.; Srai, S. K. S.; Tyrrell, R. M.; Hahn, U.; and Rice-Evans, C. (2001). Epicatechin and its in vivo metabolite, 3 '-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation. Biochemical Journal, 354, 493-500.
    • (2001) Biochemical Journal , vol.354 , pp. 493-500
    • Spencer, J.P.E.1    Schroeter, H.2    Kuhnle, G.3    Srai, S.K.S.4    Tyrrell, R.M.5    Hahn, U.6    Rice-Evans, C.7
  • 253
    • 0036920091 scopus 로고    scopus 로고
    • Superoxide scavenging by polyphenols: effect of conjugation and dimerization
    • Cano, A.; Arnao, M. B.; Williamson, G.; and Garcia-Conesa, M. T. (2002). Superoxide scavenging by polyphenols: effect of conjugation and dimerization. Redox Report, 7, 379-383.
    • (2002) Redox Report , vol.7 , pp. 379-383
    • Cano, A.1    Arnao, M.B.2    Williamson, G.3    Garcia-Conesa, M.T.4
  • 255
    • 0038291933 scopus 로고    scopus 로고
    • Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites
    • Spencer, J. P. E.; Kuhnle, G. G. C.; Williams, R. J.; and Rice-Evans, C. (2003). Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites. Biochemical Journal, 372, 173-181.
    • (2003) Biochemical Journal , vol.372 , pp. 173-181
    • Spencer, J.P.E.1    Kuhnle, G.G.C.2    Williams, R.J.3    Rice-Evans, C.4
  • 257
    • 42149105621 scopus 로고    scopus 로고
    • St. John's wort flavonolds and their metabolites show antidepressant activity and accumulate in brain after multiple oral doses
    • Paulke, A.; Noldner, M.; Schubert-Zslavecz, M.; and Wurglics, M. (2008). St. John's wort flavonolds and their metabolites show antidepressant activity and accumulate in brain after multiple oral doses. Pharmazie, 63, 296-302.
    • (2008) Pharmazie , vol.63 , pp. 296-302
    • Paulke, A.1    Noldner, M.2    Schubert-Zslavecz, M.3    Wurglics, M.4
  • 258
    • 33750096668 scopus 로고    scopus 로고
    • Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study
    • Hubbard, G. P.; Wolffram, S.; de Vos, R.; Bovy, A.; Gibbins, J. M.; and Lovegrove, J. A. (2006). Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study. British Journal of Nutrition, 96, 482-488.
    • (2006) British Journal of Nutrition , vol.96 , pp. 482-488
    • Hubbard, G.P.1    Wolffram, S.2    de Vos, R.3    Bovy, A.4    Gibbins, J.M.5    Lovegrove, J.A.6
  • 259
    • 44049084958 scopus 로고    scopus 로고
    • Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries -Implication in the anti-atherosclerotic mechanism of dietary flavonoids
    • Kawai, Y.; Nishikawa, T.; Shiba, Y.; Saito, S.; Murota, K.; Shibata, N.; Kobayashi, M.; Kanayama, M.; Uchida, K.; and Terao, J. (2008). Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries -Implication in the anti-atherosclerotic mechanism of dietary flavonoids. Journal of Biological Chemistry, 283, 9424-9434.
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 9424-9434
    • Kawai, Y.1    Nishikawa, T.2    Shiba, Y.3    Saito, S.4    Murota, K.5    Shibata, N.6    Kobayashi, M.7    Kanayama, M.8    Uchida, K.9    Terao, J.10
  • 260
    • 36249025809 scopus 로고    scopus 로고
    • Isoflavones, equol and cardiovascular disease: Pharmacological and therapeutic insights
    • Jackman, K. A.; Woodman, O. L.; and Sobey, C. G. (2007). Isoflavones, equol and cardiovascular disease: Pharmacological and therapeutic insights. Current Medicinal Chemistry, 14, 2824-2830.
    • (2007) Current Medicinal Chemistry , vol.14 , pp. 2824-2830
    • Jackman, K.A.1    Woodman, O.L.2    Sobey, C.G.3
  • 261
    • 36348962323 scopus 로고    scopus 로고
    • Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway
    • Nam Joo, K.; Ki Won, L.; Rogozin, E. A.; Yong-Yeon, C.; Yong-Seok, H.; Bode, A. M.; Hyong Joo, L.; and Zigang, D. (2007). Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway. Journal of Biological Chemistry, 282, 32856-32866.
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 32856-32866
    • Nam Joo, K.1    Ki Won, L.2    Rogozin, E.A.3    Yong-Yeon, C.4    Yong-Seok, H.5    Bode, A.M.6    Hyong Joo, L.7    Zigang, D.8
  • 262
    • 0032964360 scopus 로고    scopus 로고
    • Daidzein and genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations
    • Zhang, Y.; Song, T. T.; Cunnick, J. E.; Murphy, P. A.; and Hendrich, S. (1999). Daidzein and genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations. The Journal of Nutrition, 129, 399-405.
    • (1999) The Journal of Nutrition , vol.129 , pp. 399-405
    • Zhang, Y.1    Song, T.T.2    Cunnick, J.E.3    Murphy, P.A.4    Hendrich, S.5
  • 263
    • 34248184092 scopus 로고    scopus 로고
    • Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not
    • Niculescu, M.D.; Pop, E. A.; Fischer, L. M.; and Zeisel, S. H. (2007). Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not. Journal of Nutritional Biochemistry, 18, 380-390.
    • (2007) Journal of Nutritional Biochemistry , vol.18 , pp. 380-390
    • Niculescu, M.D.1    Pop, E.A.2    Fischer, L.M.3    Zeisel, S.H.4
  • 264
    • 36048990376 scopus 로고    scopus 로고
    • Effects of dietary equol administration on ovariectomy induced bone loss in Sprague-Dawley rats
    • Rachon, D.; Seidlova-Wuttke, D.; Vortherms, T.; and Wuttke, W. (2007). Effects of dietary equol administration on ovariectomy induced bone loss in Sprague-Dawley rats. Maturitas, 58, 308-315.
    • (2007) Maturitas , vol.58 , pp. 308-315
    • Rachon, D.1    Seidlova-Wuttke, D.2    Vortherms, T.3    Wuttke, W.4
  • 265
    • 34948839332 scopus 로고    scopus 로고
    • Effects of dietary equol on body weight gain, intra-abdominal fat accumulation, plasma lipids, and glucose tolerance in ovariectomized Sprague-Dawley rats
    • Rachon, D.; Vortherms, T.; Seidlova-Wuttke, D.; and Wuttke, W. (2007). Effects of dietary equol on body weight gain, intra-abdominal fat accumulation, plasma lipids, and glucose tolerance in ovariectomized Sprague-Dawley rats. Menopause-the Journal of the North American Menopause Society, 14, 925-932.
    • (2007) Menopause-the Journal of the North American Menopause Society , vol.14 , pp. 925-932
    • Rachon, D.1    Vortherms, T.2    Seidlova-Wuttke, D.3    Wuttke, W.4
  • 266
    • 48749084087 scopus 로고    scopus 로고
    • Comparative activities of daidzein metabolites, equol and O-desmethylangolensin, on bone mineral density and lipid metabolism in ovariectomized mice and in osteoclast cell cultures
    • Ohtomo, T.; Uehara, M.; Penalvo, J. L.; Adlercreutz, H.; Katsumata, S.; Suzuki, K.; Takeda, K.; Masuyama, R.; and Ishimi, Y. (2008). Comparative activities of daidzein metabolites, equol and O-desmethylangolensin, on bone mineral density and lipid metabolism in ovariectomized mice and in osteoclast cell cultures. European Journal of Nutrition, 47, 273-279.
    • (2008) European Journal of Nutrition , vol.47 , pp. 273-279
    • Ohtomo, T.1    Uehara, M.2    Penalvo, J.L.3    Adlercreutz, H.4    Katsumata, S.5    Suzuki, K.6    Takeda, K.7    Masuyama, R.8    Ishimi, Y.9
  • 268
    • 22244433832 scopus 로고    scopus 로고
    • Anthocyanins and colonic metabolites of dietary polyphenols inhibit platelet function
    • Rechner, A. R.; and Kroner, C. (2005). Anthocyanins and colonic metabolites of dietary polyphenols inhibit platelet function. Thrombosis Research, 116, 327-334.
    • (2005) Thrombosis Research , vol.116 , pp. 327-334
    • Rechner, A.R.1    Kroner, C.2
  • 269
    • 0031722075 scopus 로고    scopus 로고
    • Anti-inflammatory activity of myricetin-3-O-beta-D-glucuronide and related compounds
    • Hiermann, A.; Schramm, H. W.; and Laufer, S. (1998). Anti-inflammatory activity of myricetin-3-O-beta-D-glucuronide and related compounds. Inflammation Research, 47, 421-427.
    • (1998) Inflammation Research , vol.47 , pp. 421-427
    • Hiermann, A.1    Schramm, H.W.2    Laufer, S.3
  • 270
    • 33947423913 scopus 로고    scopus 로고
    • Identification of a new metabolite of astilbin, 3 '-O-methylastilbin, and its immunosuppressive activity against contact dermatitis
    • Guo, J. M.; Qian, F.; Li, J. X.; Xu, Q.; and Chen, T. (2007). Identification of a new metabolite of astilbin, 3 '-O-methylastilbin, and its immunosuppressive activity against contact dermatitis. Clinical Chemistry, 53, 465-471.
    • (2007) Clinical Chemistry , vol.53 , pp. 465-471
    • Guo, J.M.1    Qian, F.2    Li, J.X.3    Xu, Q.4    Chen, T.5
  • 272
    • 0034727789 scopus 로고    scopus 로고
    • Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin
    • Chan, F. L.; Choi, H. L.; Chen, Z. Y.; Chan, P. S. F.; and Huang, Y. (2000). Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. Cancer Letters, 160, 219-228.
    • (2000) Cancer Letters , vol.160 , pp. 219-228
    • Chan, F.L.1    Choi, H.L.2    Chen, Z.Y.3    Chan, P.S.F.4    Huang, Y.5
  • 275
    • 47349127080 scopus 로고    scopus 로고
    • Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro
    • Shukla, M.; Gupta, K.; Rasheed, Z.; Khan, K.; and Haqqi, T. (2008). Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro. Journal of Inflammation, 5, 9.
    • (2008) Journal of Inflammation , vol.5 , pp. 9
    • Shukla, M.1    Gupta, K.2    Rasheed, Z.3    Khan, K.4    Haqqi, T.5


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