Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability

Journal of Biological Chemistry

Volumn 278, Issue 37, 2003, Pages 34783-34793

  Spencer, Jeremy P E ^a   Rice Evans, Catherine ^a   Williams, Robert J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; METABOLITES; NEUROLOGY; PHOSPHORS; PROTEINS;

NEURONAL SIGNALING;

ENZYME KINETICS;

4' O METHYLQUERCETIN; CASPASE 3; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; ISORHAMNETIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; QUERCETIN; QUERCETIN DERIVATIVE; QUERCETIN O BETA DEXTRO GLUCURONIDE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; METHYLATION; MOUSE; NERVE CELL; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; KINETICS; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; QUERCETIN;

ANIMALIA;

EID: 0041816456     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305063200     Document Type: Article

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