Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids

Journal of Nutrition

Volumn 130, Issue 11, 2000, Pages 2733-2738

  Déprez, Stéphanie ^a   Brezillon, Christophe ^b   Rabot, Sylvie ^b   Philippe, Catherine ^b   Mila, Isabelle ^a   Lapierre, Catherine ^a   Scalbert, Augustin ^b  

^a AGROPARISTECH   (France)

^b CEMAGREF   (France)

Author keywords

Bioavailability; Biodegradation; Flavonoids; Human colonic microflora; Proanthocyanidins

Indexed keywords

CARBON 14; FLAVONOID; POLYMER; PROANTHOCYANIDIN;

ARTICLE; BIOAVAILABILITY; BIODEGRADATION; COLON MUCOSA; GAS CHROMATOGRAPHY; HUMAN; INTESTINE FLORA; ISOTOPE LABELING; MASS SPECTROMETRY; NONHUMAN;

EID: 0033745131     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/130.11.2733     Document Type: Article

References (38)

1. The identification of the weak oestrogen equol [7-hydroxy-3-(4'-hydroxyphenyl)chroman] in human urine
2. The excretion of lignans in rats - Evidence for an intestinal bacterial source for this new group of compounds
3. The fate of benzoic acid in various species
4. Study of the intestinal tyrosine metabolism using stable isotopes and gas chromatography-mass spectrometry
5. Studies on flavonoid metabolism. Absorption and metabolism of (+)-catechin in man
6. Metabolism of (+)-catechin in the guinea pig
7. 14C]catechin in the rat and guinea pig
8. Carbon-14 biolabeling of (+)-catechin and proanthocyanidin oligomers in willow tree cuttings
9. Microbial degradation of condensed tannins
10. Identification of the metabolites of (+)-catechin in rat urine
11. Metabolism of apigenin and related compounds in the rat
12. The microbial metabolism of (+)-catechin to two novel diarylpropan-2-ol metabolites in vitro
13. The microbial metabolism of condensed (+)-catechins by rat-caecal microflora
14. Characterization of highly polymerized procyanidins in cider apple (Malus sylvestris var kermerrien) skin and pulp
15. Reversed-phase HPLC following thiolysis for quantitative estimation and characterization of the four main classes of phenolic compounds in different tissue zones of a French cider apple variety
16. The fate of total flavanolic oligomers (OFT) extracted from Vitis vinifera L. in the rat
17. The conjugation of phenylacetic acid in phenylketonurics
18. 14C-labeled condensed tannins and related sorghum phenolics in chickens
19. Enzymatic sulfation of polyphenols related to tannins by arylsulfotransferase
20. Enzymatic sulfation of quercetin by arylsulfotransferase from human intestinal bacterium
21. The flavonoids. A class of semi-essential food components: Their role in human nutrition
22. Method for estimation of proanthocyanidins based on their acid depolymerization in the presence of nucleophiles
23. Biotransformation of (-)-epicatechin 3-O-gallate by human intestinal bacteria
24. Oligomeric and polymeric procyanidins from grape seeds
25. Phenylacetate and phenylbutyrate as novel, nontoxic differentiation inducers
26. Proanthocyanidins and tannin-like compounds in human nutrition
27. Antimicrobial properties of tannins
28. Dietary intake and bioavailability of polyphenols
29. Lignan formation in man - Microbial involvement and possible roles in relation to cancer
30. Economic importance of flavonoid compounds: Foodstuffs
31. 14C-labeled condensed tannins in the gastrointestinal tract of sheep
32. Sodium phenylacetate (NaPa) induces modifications of the proliferation, the adhesion and the cell cycle of tumoral epithelial breast cells