Methylated flavonoids have greatly improved intestinal absorption and metabolic stability

Drug Metabolism and Disposition

Volumn 34, Issue 10, 2006, Pages 1786-1792

  Wen, Xia ^a   Walle, Thomas ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,7 DIMETHOXYFLAVONE; 5,7,4' TRIMETHOXYFLAVONE; 7 HYDROXYFLAVONE; 7 METHOXYFLAVONE; 7,4' DIHYDROXYFLAVONE; 7,4' DIMETHOXYFLAVONE; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; APIGENIN; CHRYSIN; FLAVONE DERIVATIVE; FLAVONOID; POLYPHENOL DERIVATIVE; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RESVERATROL; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GALACTOSE;

ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CONJUGATION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG PENETRATION; DRUG STRUCTURE; DRUG TRANSPORT; GLUCURONIDATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE ABSORPTION; METHYLATION; OXIDATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SULFATION;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL FRACTIONATION; CELL MEMBRANE PERMEABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLAVONOIDS; GLUCURONIDES; HALF-LIFE; HUMANS; INTESTINAL ABSORPTION; METHYLATION; MICROSOMES, LIVER; MOLECULAR STRUCTURE; SULFATES;

EID: 33748916241     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.011122     Document Type: Article

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