Cellular uptake of dietary flavonoid quercetin 4'-β-glucoside by sodium-dependent glucose transporter SGLT11

Journal of Pharmacology and Experimental Therapeutics

Volumn 294, Issue 3, 2000, Pages 837-843

  Walgren, R A ^a   Lin, J T ^a   Kinne, R K H ^a   Walle, T ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVONOID; GLUCOSE; GLUCOSE TRANSPORTER; IONOPHORE; ISOQUERCITRIN; MULTIDRUG RESISTANCE PROTEIN; NYSTATIN; PHLORIZIN;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CELL STRAIN CACO 2; CELL TRANSPORT; CHO CELL; CONTROLLED STUDY; DIET; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE CELL; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; SODIUM TRANSPORT;

ANIMALS; BIOLOGICAL TRANSPORT; CELL-FREE SYSTEM; CHO CELLS; CRICETINAE; FLUORESCENCE; GLUCOSE; HUMANS; MEMBRANE GLYCOPROTEINS; MONOSACCHARIDE TRANSPORT PROTEINS; QUERCETIN; RABBITS; SODIUM; SODIUM-GLUCOSE TRANSPORTER 1; TRANSFECTION;

EID: 0033846534     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Correlation between oral drug absorption in hummus and apparent drug permeability coefficients in human intestinal (Caco-2) cells
2. Absorption and excretion of conjugated flavanols, including quercetin-4'-O-β-glucoside and isorhamnetin-4'-O-β-glucoside by human volunteers after the consumption of onions
3. Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione
4. +-dependent sugar transport in Caco-2 cells and human fetal colon
5. Hydrolysis of dietary glycosides by strains of intestinal Bacteroides from humans
6. Extensive binding of the biofiavonoid quercetin to human plasma proteins
7. Part of quercetin absorbed in the small intestine is conjugated and further secreted in the intestinal lumen
8. Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β-glucosidase activity
9. Quercetin glucosides interact with the intestinal glucose transport pathway
10. Nutritional properties and significance of vitamin glycosides
11. Metabolism of flavonoid compounds in germ-free rats
12. Disposition of quercetin in man after single oral and intravenous doses
13. Dietary antioxidant flavonoids and risk of coronary heart disease
14. Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man
15. Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers
16. Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
17. Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells
18. +/D-glucose cotransporter (SGLT1) in a stably transfected Chinese hamster ovary cell line
19. Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties
20. Active Lucifer yellow secretion in renal proximal tubule: Evidence for organic anion transport system crossover
21. Intestinal absorption of acyclovir β-glucoside: Comparative study with acyclovir, guanosine, and kinetin β-glucoside
22. Improvement of intestinal absorption of peptide drugs by glycosylation: Transport of tetra peptide by the sodium ion-dependent D-glucose transporter
23. Measurement of protein using bicinchonic acid
24. +, D-glucose cotransporter. A model
25. Absorption and metabolism of cyaniding 3-O-β-D-glucoside in rats
26. 2+ exchange activity
27. Efflux of dietary flavonoid quercetin 4'-β-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-2
28. Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells
29. Transport of genistein-7-glucoside by human intestinal Caco-2 cells: Potential role for MRP2
30. Transport of the fiavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2
31. In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man - fact or myth