메뉴 건너뛰기




Volumn 38, Issue 8, 2004, Pages 771-785

Pharmacokinetics and metabolism of dietary flavonoids in humans

Author keywords

Anthocyanins; Catechins; Flavonoids; Flavonols; Polyphenols; Proanthocyanidins

Indexed keywords

ANTHOCYANIN; APIIN; AURANTIIN; CATECHIN; CYANIDIN 3 GLUCOSIDE; DELPHINIDIN; DRUG METABOLITE; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; FLAVONE DERIVATIVE; FLAVONOID; FLAVONOL; GLUCURONIC ACID; HESPERIDIN; ISOQUERCITRIN; LUTEOLIN 7 GLUCOSIDE; MALVIN; METHYL GROUP; PELARGONIDIN 3 GLUCOSIDE; PROANTHOCYANIDIN; PROCYANIDIN B1; PROCYANIDIN B2; PROCYANIDIN B5; PROCYANIDIN DERIVATIVE; QUERCETIN DERIVATIVE; RUTOSIDE; SULFATE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 4043089112     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760410001727858     Document Type: Review
Times cited : (396)

References (111)
  • 2
    • 0016811010 scopus 로고
    • "Disposition of quercetin in man after single oral and intravenous doses"
    • Gugler, R., Leschik, M. and Dengler, H.J. (1975) "Disposition of quercetin in man after single oral and intravenous doses", Eur. J. Clin. Pharmacol. 9, 229-234.
    • (1975) Eur. J. Clin. Pharmacol. , vol.9 , pp. 229-234
    • Gugler, R.1    Leschik, M.2    Dengler, H.J.3
  • 8
    • 0033734729 scopus 로고    scopus 로고
    • "Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway"
    • Gee, J.M., DuPont, M.S., Day, A.J., Plumb, G.W., Williamson, G. and Johnson, I.T. (2000) "Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway", J. Nutr. 130, 2765-2771.
    • (2000) J. Nutr. , vol.130 , pp. 2765-2771
    • Gee, J.M.1    DuPont, M.S.2    Day, A.J.3    Plumb, G.W.4    Williamson, G.5    Johnson, I.T.6
  • 9
    • 0032566518 scopus 로고    scopus 로고
    • "Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β-glucosidase activity"
    • Day, A.J., DuPont, M.S., Ridley, S., Rhodes, M., Rhodes, M.J.C., Morgan, M.R.A. and Williamson, G. (1998) "Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β-glucosidase activity", FEBS Lett. 436, 71-75.
    • (1998) FEBS Lett. , vol.436 , pp. 71-75
    • Day, A.J.1    DuPont, M.S.2    Ridley, S.3    Rhodes, M.4    Rhodes, M.J.C.5    Morgan, M.R.A.6    Williamson, G.7
  • 10
    • 0037377562 scopus 로고    scopus 로고
    • "Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: The role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter"
    • Day, A.J., Gee, J.M., DuPont, M.S., Johnson, I.T. and Williamson, G. (2003) "Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter", Biochem. Pharmacol. 65, 1199-1206.
    • (2003) Biochem. Pharmacol. , vol.65 , pp. 1199-1206
    • Day, A.J.1    Gee, J.M.2    DuPont, M.S.3    Johnson, I.T.4    Williamson, G.5
  • 11
    • 0033847137 scopus 로고    scopus 로고
    • "Efflux of dietary flavonoid quercetin 4′-beta-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-2"
    • Walgren, R.A., Karnaky, K.J., Lindenmayer, G.E. and Walle, T. (2000) "Efflux of dietary flavonoid quercetin 4′ -beta-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-2", J. Pharmacol. Exp. Ther. 294, 830-836.
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 830-836
    • Walgren, R.A.1    Karnaky, K.J.2    Lindenmayer, G.E.3    Walle, T.4
  • 13
    • 0034054933 scopus 로고    scopus 로고
    • "Bioavailabilities of quercetin-3-glucoside and quercetin-4′-glucoside do not differ in humans"
    • Olthof, M.R., Hollman, P.C.H., Vree, T.B. and Katan, M.B. (2000) "Bioavailabilities of quercetin-3-glucoside and quercetin-4′-glucoside do not differ in humans", J. Nutr. 130, 1200-1203.
    • (2000) J. Nutr. , vol.130 , pp. 1200-1203
    • Olthof, M.R.1    Hollman, P.C.H.2    Vree, T.B.3    Katan, M.B.4
  • 15
    • 0032562766 scopus 로고    scopus 로고
    • "Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties"
    • Manach, C., Morand, C., Crespy, V., Demigne, C., Texier, O., Regerat, F. and Remesy, C. (1998) "Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties", FEBS Lett. 426, 331-336.
    • (1998) FEBS Lett. , vol.426 , pp. 331-336
    • Manach, C.1    Morand, C.2    Crespy, V.3    Demigne, C.4    Texier, O.5    Regerat, F.6    Remesy, C.7
  • 16
    • 0035692180 scopus 로고    scopus 로고
    • "Human metabolism of dietary flavonoids: Identification of plasma metabolites of quercetin"
    • Day, A.J., Mellon, F., Barron, D., Sarrazin, G., Morgan, M.R. and Williamson, G. (2001) "Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin", Free Radic Res. 35, 941-952.
    • (2001) Free Radic. Res. , vol.35 , pp. 941-952
    • Day, A.J.1    Mellon, F.2    Barron, D.3    Sarrazin, G.4    Morgan, M.R.5    Williamson, G.6
  • 17
    • 0035810344 scopus 로고    scopus 로고
    • "Identification of quercetin glucuronides in human plasma by high-performance liquid chromatography-tandem mass spectrometry"
    • Wittig, J., Herderich, M., Graefe, E.U. and Veit, M. (2001) "Identification of quercetin glucuronides in human plasma by high-performance liquid chromatography-tandem mass spectrometry", J. Chromatogr. B Biomed. Sci. Appl. 753, 237-243.
    • (2001) J. Chromatogr. B Biomed. Sci. Appl. , vol.753 , pp. 237-243
    • Wittig, J.1    Herderich, M.2    Graefe, E.U.3    Veit, M.4
  • 18
    • 0034937284 scopus 로고    scopus 로고
    • "Quercetin glucuronides but not glucosides are present in human plasma after consumption of quercetin-3-glucoside or quercetin-4′-glucoside"
    • Sesink, A.L., O'Leary, K.A. and Hollman, P.C. (2001) "Quercetin glucuronides but not glucosides are present in human plasma after consumption of quercetin-3-glucoside or quercetin-4′ -glucoside", J. Nutr. 131, 1938-1941.
    • (2001) J. Nutr. , vol.131 , pp. 1938-1941
    • Sesink, A.L.1    O'Leary, K.A.2    Hollman, P.C.3
  • 20
    • 0034073446 scopus 로고    scopus 로고
    • "Prediction of dietary flavonol consumption from fasting plasma concentration or urinary excretion"
    • Noroozi, M., Burns, J., Crozier, A., Kelly, I.E. and Lean, M.E. (2000) "Prediction of dietary flavonol consumption from fasting plasma concentration or urinary excretion", Eur. J. Clin. Nutr. 54, 143-149.
    • (2000) Eur. J. Clin. Nutr. , vol.54 , pp. 143-149
    • Noroozi, M.1    Burns, J.2    Crozier, A.3    Kelly, I.E.4    Lean, M.E.5
  • 21
    • 0036737867 scopus 로고    scopus 로고
    • "Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables"
    • Erlund, I., Silaste, M.L., Alfthan, G., Rantala, M., Kesaniemi, Y.A. and Aro, A. (2002) "Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables", Eur. J. Clin. Nutr. 56, 891-898.
    • (2002) Eur. J. Clin. Nutr. , vol.56 , pp. 891-898
    • Erlund, I.1    Silaste, M.L.2    Alfthan, G.3    Rantala, M.4    Kesaniemi, Y.A.5    Aro, A.6
  • 23
    • 0031956125 scopus 로고    scopus 로고
    • "Supplementation with quercetin markedly increases plasma quercetin concentration without effect on selected risk factors for heart disease in healthy subjects"
    • Conquer, J.A., Maiani, G., Azzini, E., Raguzzini, A. and Holub, B.J. (1998) "Supplementation with quercetin markedly increases plasma quercetin concentration without effect on selected risk factors for heart disease in healthy subjects", J. Nutr. 128, 593-597.
    • (1998) J. Nutr. , vol.128 , pp. 593-597
    • Conquer, J.A.1    Maiani, G.2    Azzini, E.3    Raguzzini, A.4    Holub, B.J.5
  • 25
    • 0032839389 scopus 로고    scopus 로고
    • "Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects"
    • Nielsen, S.E., Young, J.F., Daneshvar, B., Lauridsen, S.T., Knuthsen, P., Sandstrom, B. and Dragsted, L.O. (1999) "Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects", Br. J. Nutr. 81, 447-455.
    • (1999) Br. J. Nutr. , vol.81 , pp. 447-455
    • Nielsen, S.E.1    Young, J.F.2    Daneshvar, B.3    Lauridsen, S.T.4    Knuthsen, P.5    Sandstrom, B.6    Dragsted, L.O.7
  • 26
    • 0034492864 scopus 로고    scopus 로고
    • "Metabolic fate of luteolin and its functional activity at focal site"
    • Shimoi, K., Saka, N., Kaji, K., Nozawa, R. and Kinae, N. (2000) "Metabolic fate of luteolin and its functional activity at focal site", Biofactors 12, 181-186.
    • (2000) Biofactors , vol.12 , pp. 181-186
    • Shimoi, K.1    Saka, N.2    Kaji, K.3    Nozawa, R.4    Kinae, N.5
  • 27
    • 0141972914 scopus 로고    scopus 로고
    • "Bioavailability and antioxidant properties of luteolin"
    • Kumpulainen, J.T. and Salonen, J.T., eds, Natural Antioxidants and Anticarcinogens in Nutrition, (The Royal Society of Chemistry, Cambridge, UK)
    • Shimoi, K., Okada, H., Kaneko, J., Furugori, M., Goda, T., Takase, S., Suzuki, M., Hara, Y. and Kinae, N. (1999) " Bioavailability and antioxidant properties of luteolin", In: Kumpulainen, J.T. and Salonen, J.T., eds, Natural Antioxidants and Anticarcinogens in Nutrition, Health and Disease (The Royal Society of Chemistry, Cambridge, UK), pp 167-173.
    • (1999) Health and Disease , pp. 167-173
    • Shimoi, K.1    Okada, H.2    Kaneko, J.3    Furugori, M.4    Goda, T.5    Takase, S.6    Suzuki, M.7    Hara, Y.8    Kinae, N.9
  • 28
  • 29
    • 0028973416 scopus 로고
    • "The fate of naringin in humans: A key to grapefruit juice-drug interactions?"
    • Fuhr, U. and Kummert, A.L. (1995) "The fate of naringin in humans: a key to grapefruit juice-drug interactions?", Clin. Pharmacol. Ther. 58, 365-373.
    • (1995) Clin. Pharmacol. Ther. , vol.58 , pp. 365-373
    • Fuhr, U.1    Kummert, A.L.2
  • 31
    • 0037327340 scopus 로고    scopus 로고
    • "Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice"
    • Manach, C., Morand, C., Gil-Izquierdo, A., Bouteloup-Demange, C. and Remesy, C. (2003) "Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice", Eur. J. Clin. Nutr. 57, 235-242.
    • (2003) Eur. J. Clin. Nutr. , vol.57 , pp. 235-242
    • Manach, C.1    Morand, C.2    Gil-Izquierdo, A.3    Bouteloup-Demange, C.4    Remesy, C.5
  • 32
    • 4043161693 scopus 로고    scopus 로고
    • Polyphenols Communications Paper presented at: XXI International Conference on Polyphenols, (2002); Marrakech, Marocco
    • Manach C, Morand C, Rémésy, C. Polyphenols Communications (2002) Paper presented at: XXI International Conference on Polyphenols, (2002); Marrakech, Marocco.
    • (2002)
    • Manach, C.1    Morand, C.2    Rémésy, C.3
  • 33
    • 0036846041 scopus 로고    scopus 로고
    • "Naringenin from cooked tomato paste is bioavailable in men"
    • Bugianesi, R., Catasta, G., Spigno, P., D'Uva, A. and Maiani, G. (2002) "Naringenin from cooked tomato paste is bioavailable in men", J. Nutr. 132, 3349-3352.
    • (2002) J. Nutr. , vol.132 , pp. 3349-3352
    • Bugianesi, R.1    Catasta, G.2    Spigno, P.3    D'Uva, A.4    Maiani, G.5
  • 34
    • 0001456497 scopus 로고
    • "Anthocyanin analysis as a measure of glycosidase activity in enzymes for juice processing"
    • Wightman, J.D. and Wrolstad, R.E. (1995) "Anthocyanin analysis as a measure of glycosidase activity in enzymes for juice processing", J. Food Sci. 60, 862-867.
    • (1995) J. Food Sci. , vol.60 , pp. 862-867
    • Wightman, J.D.1    Wrolstad, R.E.2
  • 35
    • 0029800393 scopus 로고    scopus 로고
    • "Beta-glucosidase activity in juice-processing enzymes based on anthocyanin analysis"
    • Wightman, J.D. and Wrolstad, R.E. (1996) "Beta-glucosidase activity in juice-processing enzymes based on anthocyanin analysis" , J. Food Sci., 61.
    • (1996) J. Food Sci. , pp. 61
    • Wightman, J.D.1    Wrolstad, R.E.2
  • 36
  • 37
    • 0141850470 scopus 로고    scopus 로고
    • "Screening of foods containing proanthocyanidins and their structural characterization using LC-MS/MS and thiolytic degradation"
    • Gu, L., Kelm, M.A., Hammerstone, J.F., Beecher, G., Holden, J., Haytowitz, D. and Prior, R.L. (2003) "Screening of foods containing proanthocyanidins and their structural characterization using LC-MS/MS and thiolytic degradation", J. Agric. Food Chem. 51, 7513-7521.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 7513-7521
    • Gu, L.1    Kelm, M.A.2    Hammerstone, J.F.3    Beecher, G.4    Holden, J.5    Haytowitz, D.6    Prior, R.L.7
  • 39
    • 0035135570 scopus 로고    scopus 로고
    • "Catechin intake and associated dietary and lifestyle factors in a representative sample of Dutch men and women"
    • Arts, I.C.W., Hollman, P.C.H., Feskens, E.J.M., deMesquita, H.B.B. and Kromhout, D. (2001) "Catechin intake and associated dietary and lifestyle factors in a representative sample of Dutch men and women", Eur. J. Clin. Nutr. 55, 76-81.
    • (2001) Eur. J. Clin. Nutr. , vol.55 , pp. 76-81
    • Arts, I.C.W.1    Hollman, P.C.H.2    Feskens, E.J.M.3    deMesquita, H.B.B.4    Kromhout, D.5
  • 40
    • 4043062542 scopus 로고    scopus 로고
    • Analisis de taninos condensados en alimentos
    • Universidad de Salamanca (Salamanca). Ph.D. Thesis
    • de Pascual-Teresa, S. (1999) Analisis de taninos condensados en alimentos [Ph.D. Thesis]. Universidad de Salamanca (Salamanca).
    • (1999)
    • de Pascual-Teresa, S.1
  • 41
    • 0034106431 scopus 로고    scopus 로고
    • "Catechin contents of foods commonly consumed in The Netherlands. 1. Fruits, vegetables, staple foods, and processed foods"
    • Arts, I.C.W., vandePutte, B. and Hollman, P.C.H. (2000) "Catechin contents of foods commonly consumed in The Netherlands. 1. Fruits, vegetables, staple foods, and processed foods", J. Agric. Food Chem. 48, 1746-1751.
    • (2000) J. Agric. Food Chem. , vol.48 , pp. 1746-1751
    • Arts, I.C.W.1    vandePutte, B.2    Hollman, P.C.H.3
  • 43
    • 0031903559 scopus 로고    scopus 로고
    • "Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers"
    • Yang, C.S., Chen, L., Lee, M.J., Balentine, D., Kuo, M.C. and Schantz, S.P. (1998) "Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers", Cancer Epidemiol. Biomark. Prev. 7, 351-354.
    • (1998) Cancer Epidemiol. Biomark. Prev. , vol.7 , pp. 351-354
    • Yang, C.S.1    Chen, L.2    Lee, M.J.3    Balentine, D.4    Kuo, M.C.5    Schantz, S.P.6
  • 44
    • 0036801990 scopus 로고    scopus 로고
    • "Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: Formation of different metabolites and individual variability"
    • Lee, M.J., Maliakal, P., Chen, L., Meng, X., Bondoc, F.Y., Prabhu, S., Lambert, G., Mohr, S. and Yang, C.S. (2002) "Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability", Cancer Epidemiol. Biomark. Prev. 11, 1025-1032.
    • (2002) Cancer Epidemiol. Biomark. Prev. , vol.11 , pp. 1025-1032
    • Lee, M.J.1    Maliakal, P.2    Chen, L.3    Meng, X.4    Bondoc, F.Y.5    Prabhu, S.6    Lambert, G.7    Mohr, S.8    Yang, C.S.9
  • 46
    • 0034982460 scopus 로고    scopus 로고
    • "Catechins are bioavailable in men and women drinking black tea throughout the day"
    • Warden, B.A., Smith, L.S., Beecher, G.R., Balentine, D.A. and Clevidence, B.A. (2001) "Catechins are bioavailable in men and women drinking black tea throughout the day", J. Nutr. 131, 1731-1737.
    • (2001) J. Nutr. , vol.131 , pp. 1731-1737
    • Warden, B.A.1    Smith, L.S.2    Beecher, G.R.3    Balentine, D.A.4    Clevidence, B.A.5
  • 48
    • 0033867415 scopus 로고    scopus 로고
    • "Epicatechin in human plasma: In vivo determination and effect of chocolate consumption on plasma oxidation status"
    • Rein, D., Lotito, S., Holt, R.R., Keen, C.L., Schmitz, H.H. and Fraga, C.G. (2000) "Epicatechin in human plasma: In vivo determination and effect of chocolate consumption on plasma oxidation status", J. Nutr. 130, 2109S-2114S.
    • (2000) J. Nutr. , vol.130
    • Rein, D.1    Lotito, S.2    Holt, R.R.3    Keen, C.L.4    Schmitz, H.H.5    Fraga, C.G.6
  • 49
    • 0033867144 scopus 로고    scopus 로고
    • "A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage"
    • Wang, J.F., Schramm, D.D., Holt, R.R., Ensunsa, J.L., Fraga, C.G., Schmitz, H.H. and Keen, C.L. (2000) "A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage", J. Nutr. 130, 2115S-2119S.
    • (2000) J. Nutr. , vol.130
    • Wang, J.F.1    Schramm, D.D.2    Holt, R.R.3    Ensunsa, J.L.4    Fraga, C.G.5    Schmitz, H.H.6    Keen, C.L.7
  • 50
    • 0032893641 scopus 로고    scopus 로고
    • "Plasma kinetics in man of epicatechin from black chocolate"
    • Richelle, M., Tavazzi, I., Enslen, M. and Offord, E.A. (1999) "Plasma kinetics in man of epicatechin from black chocolate", Eur. J. Clin. Nutr. 53, 22-26.
    • (1999) Eur. J. Clin. Nutr. , vol.53 , pp. 22-26
    • Richelle, M.1    Tavazzi, I.2    Enslen, M.3    Offord, E.A.4
  • 51
    • 0034493222 scopus 로고    scopus 로고
    • "Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers"
    • Baba, S., Osakabe, N., Yasuda, A., Natsume, M., Takizawa, T., Nakamura, T. and Terao, J. (2000) "Bioavailability of (- -epicatechin upon intake of chocolate and cocoa in human volunteers" , Free Radic. Res. 33, 635-641.
    • (2000) Free Radic. Res. , vol.33 , pp. 635-641
    • Baba, S.1    Osakabe, N.2    Yasuda, A.3    Natsume, M.4    Takizawa, T.5    Nakamura, T.6    Terao, J.7
  • 56
    • 0036667454 scopus 로고    scopus 로고
    • "Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats"
    • Meng, X., Sang, S., Zhu, N., Lu, H., Sheng, S., Lee, M.J., Ho, C.T. and Yang, C.S. (2002) "Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats", Chem. Res. Toxicol. 15, 1042-1050.
    • (2002) Chem. Res. Toxicol. , vol.15 , pp. 1042-1050
    • Meng, X.1    Sang, S.2    Zhu, N.3    Lu, H.4    Sheng, S.5    Lee, M.J.6    Ho, C.T.7    Yang, C.S.8
  • 59
    • 0037376885 scopus 로고    scopus 로고
    • "Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: Differences between human and rat"
    • Natsume, M., Osakabe, N., Oyama, M., Sasaki, M., Baba, S., Nakamura, Y., Osawa, T. and Terao, J. (2003) "Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: differences between human and rat", Free Radic. Biol. Med. 34, 840-849.
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 840-849
    • Natsume, M.1    Osakabe, N.2    Oyama, M.3    Sasaki, M.4    Baba, S.5    Nakamura, Y.6    Osawa, T.7    Terao, J.8
  • 60
    • 0017649747 scopus 로고
    • "Etude pharmacocinétique des oligomères flavanoliques"
    • Laparra, J., Michaud, J. and Masquelier, J. (1977) "Etude pharmacocinétique des oligomères flavanoliques", Plant Med. Phytother. 11, 133-142.
    • (1977) Plant Med. Phytother. , vol.11 , pp. 133-142
    • Laparra, J.1    Michaud, J.2    Masquelier, J.3
  • 61
    • 0018171892 scopus 로고
    • "The fate of total flavanolic oligomers (OFT) extracted from Vitis vinifera L. in the rat"
    • Harmand, M.F. and Blanquet, P. (1978) "The fate of total flavanolic oligomers (OFT) extracted from Vitis vinifera L. in the rat", Eur. J. Drug Metabol. Pharmacokinet. 3, 15-30.
    • (1978) Eur. J. Drug Metabol. Pharmacokinet. , vol.3 , pp. 15-30
    • Harmand, M.F.1    Blanquet, P.2
  • 62
    • 0037316953 scopus 로고    scopus 로고
    • "Microbial aromatic acid metabolites formed in the gut account for a major fraction of the polyphenols excreted in urine of rats fed red wine polyphenols"
    • Gonthier, M.P., Cheynier, V., Donovan, J.L., Manach, C., Morand, C., Mila, I., Lapierre, C., Remesy, C. and Scalbert, A. (2003) "Microbial aromatic acid metabolites formed in the gut account for a major fraction of the polyphenols excreted in urine of rats fed red wine polyphenols", J. Nutr. 133, 461-467.
    • (2003) J. Nutr. , vol.133 , pp. 461-467
    • Gonthier, M.P.1    Cheynier, V.2    Donovan, J.L.3    Manach, C.4    Morand, C.5    Mila, I.6    Lapierre, C.7    Remesy, C.8    Scalbert, A.9
  • 63
    • 0000158269 scopus 로고
    • "Absorption and distribution of C-14-labelled condensed tannins and related sorghum phenolics in chickens"
    • Jimenez-Ramsey, L.M., Rogler, J.C., Housley, T.L., Butler, L.G. and Elkin, R.G. (1994) "Absorption and distribution of C-14-labelled condensed tannins and related sorghum phenolics in chickens", J. Agric. Food Chem. 42, 963-967.
    • (1994) J. Agric. Food Chem. , vol.42 , pp. 963-967
    • Jimenez-Ramsey, L.M.1    Rogler, J.C.2    Housley, T.L.3    Butler, L.G.4    Elkin, R.G.5
  • 65
    • 0344613481 scopus 로고    scopus 로고
    • "Procyanidin B1 is detected in human serum after intake of proanthocyanidin-rich grape seed extract"
    • Sano, A., Yamakoshi, J., Tokutake, S., Tobe, K., Kubota, Y. and Kikuchi, M. (2003) "Procyanidin B1 is detected in human serum after intake of proanthocyanidin-rich grape seed extract", Biosci. Biotechnol. Biochem. 67, 1140-1143.
    • (2003) Biosci. Biotechnol. Biochem. , vol.67 , pp. 1140-1143
    • Sano, A.1    Yamakoshi, J.2    Tokutake, S.3    Tobe, K.4    Kubota, Y.5    Kikuchi, M.6
  • 67
    • 0035885034 scopus 로고    scopus 로고
    • 14C-labelled proanthocyanidins from carob (Ceratonia siliqua) pods in the gastrointestinal tract of the rat"
    • 14C-labelled proanthocyanidins from carob (Ceratonia siliqua) pods in the gastrointestinal tract of the rat", J. Sci. Food Agric. 81, 1156-1165.
    • (2001) J. Sci. Food Agric. , vol.81 , pp. 1156-1165
    • Abia, R.1    Fry, S.C.2
  • 68
    • 0034811344 scopus 로고    scopus 로고
    • "Epicatechin is the primary bioavailable form of the procyanidin dimers B2 and B5 after transfer across the small intestine"
    • Spencer, J.P., Schroeter, H., Shenoy, B., Srai, S.K., Debnam, E.S. and Rice-Evans, C. (2001) "Epicatechin is the primary bioavailable form of the procyanidin dimers B2 and B5 after transfer across the small intestine", Biochem. Biophys. Res. Commun. 285, 588-593.
    • (2001) Biochem. Biophys. Res. Commun. , vol.285 , pp. 588-593
    • Spencer, J.P.1    Schroeter, H.2    Shenoy, B.3    Srai, S.K.4    Debnam, E.S.5    Rice-Evans, C.6
  • 69
    • 0036165985 scopus 로고    scopus 로고
    • "Urinary excretion of catechin metabolites by human subjects after red wine consumption"
    • Donovan, J.L., Kasim-Karakas, S., German, J.B. and Waterhouse, A.L. (2002) "Urinary excretion of catechin metabolites by human subjects after red wine consumption", Br. J. Nutr. 87, 31-37.
    • (2002) Br. J. Nutr. , vol.87 , pp. 31-37
    • Donovan, J.L.1    Kasim-Karakas, S.2    German, J.B.3    Waterhouse, A.L.4
  • 71
    • 0345168969 scopus 로고    scopus 로고
    • "Anthocyanins are efficiently absorbed from the stomach in anesthetized rats"
    • Talavera, S., Felgines, C., Texier, O., Besson, C., Lamaison, J.L. and Remesy, C. (2003) "Anthocyanins are efficiently absorbed from the stomach in anesthetized rats", J. Nutr. 133, 4178-4182.
    • (2003) J. Nutr. , vol.133 , pp. 4178-4182
    • Talavera, S.1    Felgines, C.2    Texier, O.3    Besson, C.4    Lamaison, J.L.5    Remesy, C.6
  • 72
    • 0038018460 scopus 로고    scopus 로고
    • "The stomach as a site for anthocyanins absorption from food"
    • Passamonti, S., Vrhovsek, U., Vanzo, A. and Mattivi, F. (2003) "The stomach as a site for anthocyanins absorption from food", FEBS Lett. 544, 210-213.
    • (2003) FEBS Lett. , vol.544 , pp. 210-213
    • Passamonti, S.1    Vrhovsek, U.2    Vanzo, A.3    Mattivi, F.4
  • 73
    • 0000512510 scopus 로고    scopus 로고
    • "Bioavailability of red wine anthocyanins as detected in human urine"
    • Lapidot, T., Harel, S., Granit, R. and Kanner, J. (1998) "Bioavailability of red wine anthocyanins as detected in human urine", J. Agric. Food Chem. 46, 4297-4302.
    • (1998) J. Agric. Food Chem. , vol.46 , pp. 4297-4302
    • Lapidot, T.1    Harel, S.2    Granit, R.3    Kanner, J.4
  • 74
  • 75
    • 0035046914 scopus 로고    scopus 로고
    • "Anthocyanins are absorbed in glycated forms in elderly women: A pharmacokinetic study"
    • Cao, G., Muccitelli, H.U., Sanchez-Moreno, C. and Prior, R.L. (2001) "Anthocyanins are absorbed in glycated forms in elderly women: a pharmacokinetic study", Am. J. Clin. Nutr. 73, 920-926.
    • (2001) Am. J. Clin. Nutr. , vol.73 , pp. 920-926
    • Cao, G.1    Muccitelli, H.U.2    Sanchez-Moreno, C.3    Prior, R.L.4
  • 76
    • 0036300211 scopus 로고    scopus 로고
    • "Absorption and metabolism of anthocyanins in elderly women after consumption of elderberry or blueberry"
    • Wu, X., Cao, G. and Prior, R.L. (2002) "Absorption and metabolism of anthocyanins in elderly women after consumption of elderberry or blueberry", J. Nutr. 132, 1865-1871.
    • (2002) J. Nutr. , vol.132 , pp. 1865-1871
    • Wu, X.1    Cao, G.2    Prior, R.L.3
  • 77
    • 0023278775 scopus 로고
    • "Effects of antibiotic pretreatments on the metabolism and excretion of [U14C](+)-catechin [(U14C](+)-cyanidanol-3) and its metabolite, 3′-O-methyl-(+)-catechin"
    • Gott, D.M. and Griffiths, L.A. (1987) "Effects of antibiotic pretreatments on the metabolism and excretion of [U14C](+)-catechin [(U14C](+)-cyanidanol-3) and its metabolite, 3′-O-methyl-(+)-catechin", Xenobiotica 17, 423-434.
    • (1987) Xenobiotica , vol.17 , pp. 423-434
    • Gott, D.M.1    Griffiths, L.A.2
  • 78
    • 0014382799 scopus 로고
    • "Studies on flavonoid metabolism. Metabolism of (+)-catechin in the guinea pig"
    • Das, N.P. and Griffiths, L.A. (1968) "Studies on flavonoid metabolism. Metabolism of (+)-catechin in the guinea pig", Biochem. J. 110, 449-456.
    • (1968) Biochem. J. , vol.110 , pp. 449-456
    • Das, N.P.1    Griffiths, L.A.2
  • 79
    • 0034838504 scopus 로고    scopus 로고
    • "Metabolic fate of (-)-[4-(3)H]epigallocatechin gallate in rats after oral administration"
    • Kohri, T., Matsumoto, N., Yamakawa, M., Suzuki, M., Nanjo, F., Hara, Y. and Oku, N. (2001) "Metabolic fate of (-)-[4-(3)H]epigallocatechin gallate in rats after oral administration", J. Agric. Food Chem. 49, 4102-4112.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 4102-4112
    • Kohri, T.1    Matsumoto, N.2    Yamakawa, M.3    Suzuki, M.4    Nanjo, F.5    Hara, Y.6    Oku, N.7
  • 80
    • 0034967897 scopus 로고    scopus 로고
    • "Analysis of urinary metabolites of tea catechins by liquid chromatography/ electrospray ionization mass spectrometry"
    • Li, C., Meng, X., Winnik, B., Lee, M.J., Lu, H., Sheng, S., Buckley, B. and Yang, C.S. (2001) "Analysis of urinary metabolites of tea catechins by liquid chromatography/ electrospray ionization mass spectrometry", Chem. Res. Toxicol. 14, 702-707.
    • (2001) Chem. Res. Toxicol. , vol.14 , pp. 702-707
    • Li, C.1    Meng, X.2    Winnik, B.3    Lee, M.J.4    Lu, H.5    Sheng, S.6    Buckley, B.7    Yang, C.S.8
  • 81
    • 0031009218 scopus 로고    scopus 로고
    • "Biotransformation of (-)-epicatechin 3-O-gallate by human intestinal bacteria"
    • Meselhy, M.R., Nakamura, N. and Hattori, M. (1997) "Biotransformation of (-)-epicatechin 3-O-gallate by human intestinal bacteria", Chem. Pharm. Bull. 45, 888-893.
    • (1997) Chem. Pharm. Bull. , vol.45 , pp. 888-893
    • Meselhy, M.R.1    Nakamura, N.2    Hattori, M.3
  • 82
    • 0033745131 scopus 로고    scopus 로고
    • "Polymeric proanthocyanidins are catabolized by a human colonic microflora into low molecular weight phenolic acids"
    • Déprez, S., Brézillon, C., Rabot, S., Philippe, C., Mila, I., Lapierre, C. and Scalbert, A. (2000) "Polymeric proanthocyanidins are catabolized by a human colonic microflora into low molecular weight phenolic acids", J. Nutr. 130, 2733-2738.
    • (2000) J. Nutr. , vol.130 , pp. 2733-2738
    • Déprez, S.1    Brézillon, C.2    Rabot, S.3    Philippe, C.4    Mila, I.5    Lapierre, C.6    Scalbert, A.7
  • 83
    • 0000823220 scopus 로고
    • "The metabolic fate of rutin and quercetin in the animal body"
    • Booth, A.N., Deeds, F., Jones, F.T. and Murray, C.W. (1956) "The metabolic fate of rutin and quercetin in the animal body" , J. Biol. Chem. 223, 251-257.
    • (1956) J. Biol. Chem. , vol.223 , pp. 251-257
    • Booth, A.N.1    Deeds, F.2    Jones, F.T.3    Murray, C.W.4
  • 84
    • 0019866704 scopus 로고
    • "Studies on drug metabolism by use of isotopes. XXVI. Determination of urinary metabolites of rutin in humans"
    • Baba, S., Furuta, T., Horie, M. and Nakagawa, H. (1981) "Studies on drug metabolism by use of isotopes. XXVI. Determination of urinary metabolites of rutin in humans", J. Pharm. Sci. 70, 780-782.
    • (1981) J. Pharm. Sci. , vol.70 , pp. 780-782
    • Baba, S.1    Furuta, T.2    Horie, M.3    Nakagawa, H.4
  • 87
    • 0023234225 scopus 로고
    • "Serum concentrations of rutoside metabolites after oral administration of a rutoside formulation to humans"
    • Sawai, Y., Kohsaka, K., Nishiyama, Y. and Ando, K. (1987) "Serum concentrations of rutoside metabolites after oral administration of a rutoside formulation to humans", Arzneimittelforschung 37, 729-732.
    • (1987) Arzneimittelforschung , vol.37 , pp. 729-732
    • Sawai, Y.1    Kohsaka, K.2    Nishiyama, Y.3    Ando, K.4
  • 88
    • 0034795649 scopus 로고    scopus 로고
    • "Carbon dioxide is the major metabolite of quercetin in humans"
    • Walle, T., Walle, U.K. and Halushka, P.V. (2001) "Carbon dioxide is the major metabolite of quercetin in humans", J. Nutr. 131, 2648-2652.
    • (2001) J. Nutr. , vol.131 , pp. 2648-2652
    • Walle, T.1    Walle, U.K.2    Halushka, P.V.3
  • 93
    • 0032930287 scopus 로고    scopus 로고
    • "Absorption and metabolism of cyanidin 3-O-beta-D-glucoside in rats"
    • Tsuda, T., Horio, F. and Osawa, T. (1999) "Absorption and metabolism of cyanidin 3-O-beta-D-glucoside in rats", FEBS Lett. 449, 179-182.
    • (1999) FEBS Lett. , vol.449 , pp. 179-182
    • Tsuda, T.1    Horio, F.2    Osawa, T.3
  • 94
    • 0015361661 scopus 로고
    • "Metabolism of apigenin and related compounds in the rat"
    • Griffiths, L.A. and Smith, G.E. (1972) "Metabolism of apigenin and related compounds in the rat", Biochem. J. 128, 901-911.
    • (1972) Biochem. J. , vol.128 , pp. 901-911
    • Griffiths, L.A.1    Smith, G.E.2
  • 97
    • 70449168814 scopus 로고
    • "Metabolic fate of hesperidin, eriodictyol, homoeriodictyol, and diosmin"
    • Booth, A.N., Jones, F.T. and De Eds, F. (1958) "Metabolic fate of hesperidin, eriodictyol, homoeriodictyol, and diosmin", J. Biol. Chem. 230, 661-668.
    • (1958) J. Biol. Chem. , vol.230 , pp. 661-668
    • Booth, A.N.1    Jones, F.T.2    De Eds, F.3
  • 100
    • 0344903926 scopus 로고
    • "Green and black tea consumption by humans: Impact on polyphenol concentrations in feces, blood and urine"
    • He, Y.H. and Kies, C. (1994) "Green and black tea consumption by humans: impact on polyphenol concentrations in feces, blood and urine", Plant Foods Hum. Nutr. 46, 221-229.
    • (1994) Plant Foods Hum. Nutr. , vol.46 , pp. 221-229
    • He, Y.H.1    Kies, C.2
  • 101
    • 0008887680 scopus 로고
    • "Chemical reaction detection of catechins and proanthocyanidins with 4-dimethylaminocinnamaldehyde"
    • Treutter, D. (1989) "Chemical reaction detection of catechins and proanthocyanidins with 4-dimethylaminocinnamaldehyde" , J. Chromatogr. 467, 185-193.
    • (1989) J. Chromatogr. , vol.467 , pp. 185-193
    • Treutter, D.1
  • 102
    • 0035063656 scopus 로고    scopus 로고
    • "Addition of milk does not affect the absorption of flavonols from tea in man"
    • Hollman, P.C., Van Het Hof, K.H., L.B., Tijburg and Katan, M.B. (2001) "Addition of milk does not affect the absorption of flavonols from tea in man", Free Radic. Res. 34, 297-300.
    • (2001) Free Radic. Res. , vol.34 , pp. 297-300
    • Hollman, P.C.1    Van Het Hof, K.H.2    Tijburg, L.B.3    Katan, M.B.4
  • 108
    • 0035150315 scopus 로고    scopus 로고
    • "Plasma kinetics and urinary excretion of the flavanones naringenin and hespeřetin in humans after ingestion of orange juice and grapefruit juice"
    • Erlund, I., Meririnne, E., Alfthan, G. and Aro, A. (2001) "Plasma kinetics and urinary excretion of the flavanones naringenin and hespeřetin in humans after ingestion of orange juice and grapefruit juice", J. Nutr. 131, 235-241.
    • (2001) J. Nutr. , vol.131 , pp. 235-241
    • Erlund, I.1    Meririnne, E.2    Alfthan, G.3    Aro, A.4
  • 109
    • 0037462059 scopus 로고    scopus 로고
    • "Absorption and excretion of black currant anthocyanins in humans and watanable heritable hyperlipidemic rabbits"
    • Neilsen, I.L., Dragsted, L.O., Ravn-Haren, G., Freese, R. and Rasmussen, S.E. (2003) "Absorption and excretion of black currant anthocyanins in humans and watanable heritable hyperlipidemic rabbits", J. Agric. Food. Chem. 51, 2813-2820.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 2813-2820
    • Neilsen, I.L.1    Dragsted, L.O.2    Ravn-Haren, G.3    Freese, R.4    Rasmussen, S.E.5
  • 110
    • 0034788719 scopus 로고    scopus 로고
    • "Malvidin-3-glucoside bioavailability in humans after ingesion of red wine, dealcoholized red wine and red grape juice"
    • Bub, A., Watzl, B., Heeb, D., Rechkemmer, G. and Briviba, K. (2001) "Malvidin-3-glucoside bioavailability in humans after ingesion of red wine, dealcoholized red wine and red grape juice", Eur. J. Nutr. 40, 113-120.
    • (2001) Eur. J. Nutr. , vol.40 , pp. 113-120
    • Bub, A.1    Watzl, B.2    Heeb, D.3    Rechkemmer, G.4    Briviba, K.5
  • 111
    • 0032915558 scopus 로고    scopus 로고
    • "Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3,5-diglucoside into rats and humans"
    • Miyazawa, T., Nakagawa, K., Kudo, M., Muraishi, K. and Someya, K. (1999) "Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3,5-diglucoside into rats and humans", J. Agric. Food. Chem 47, 1083-1091.
    • (1999) J. Agric. Food. Chem , vol.47 , pp. 1083-1091
    • Miyazawa, T.1    Nakagawa, K.2    Kudo, M.3    Muraishi, K.4    Someya, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.