Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption

Molecular Pharmaceutics

Volumn 4, Issue 6, 2007, Pages 826-832

  Walle, Thomas ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Bioavailability; Cell proliferation; Flavones; Flavonoids; Metabolic resistance; Methylation

Indexed keywords

5 METHOXYFLAVONE; 5,7 DIMETHOXYFLAVONE; 5,7,4' TRIMETHOXYFLAVONE; 7 HYDROXYFLAVONE; 7 METHOXYFLAVONE; 7,4' DIMETHOXYFLAVONE; APIGENIN; AROMATASE; BIOCHANIN A; CHRYSIN; CHRYSIN GLUCURONIDE; CHRYSIN SULFATE; FLAVONE DERIVATIVE; FLAVONOID; FORMONONETIN; GALANGIN; GENISTEIN; GLUCURONIC ACID; GLUCURONOSYLTRANSFERASE 1A9; HYDROXYL GROUP; ISOKAEMPFERIDE; METHOXYFLAVONE DERIVATIVE; POLYPHENOL; PRUNETIN; QUERCETIN; RESVERATROL; SULFATE; TANGERETIN; UNCLASSIFIED DRUG;

BIOLOGICAL ACTIVITY; CANCER CELL; CELL PROLIFERATION; CHEMOPROPHYLAXIS; COMBINATION CHEMOTHERAPY; DIETARY INTAKE; DRUG BINDING; DRUG BIOAVAILABILITY; DRUG CONJUGATION; DRUG MEGADOSE; DRUG METABOLISM; DRUG STABILITY; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VIVO STUDY; INTESTINE ABSORPTION; LIVER MICROSOME; METHYLATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REVIEW; SINGLE DRUG DOSE; TISSUE DISTRIBUTION;

ANIMALS; BIOLOGICAL AVAILABILITY; CELL PROLIFERATION; DIET; FLAVONES; HUMANS; INTESTINAL ABSORPTION; LIVER; METHYLATION; TISSUE DISTRIBUTION;

EID: 37549024168     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp700071d     Document Type: Review

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