Assessment of intestinal absorption of vitexin-2″-O-rhamnoside in hawthorn leaves flavonoids in rat using in situ and in vitro absorption models

Drug Development and Industrial Pharmacy

Volumn 34, Issue 2, 2008, Pages 164-170

  Xu, Ying Ai ^a   Fan, Guorong ^a   Gao, Shen ^a   Hong, Zhanying ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Everted gut sac; Hawthorn leaves flavonoids; Intestinal absorption; P glycoprotein; Single pass perfusion; Vitexin 2 O rhamnoside

Indexed keywords

CRATAEGUS EXTRACT; DIGOXIN; FLAVONOID; GLYCOPROTEIN P INHIBITOR; UNCLASSIFIED DRUG; VERAPAMIL; VITEXIN 2'' RHAMNOSIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APPARENT PERMEABILITY COEFFICIENT; ARTICLE; CALCULATION; COLON; CONTROLLED STUDY; CRATAEGUS; DRUG ABSORPTION; DRUG MECHANISM; DRUG PENETRATION; DUODENUM; EFFECTIVE PERMEABILITY COEFFICIENT; EXPERIMENTAL MODEL; ILEUM; IN VITRO STUDY; INTESTINE; INTESTINE ABSORPTION; INTESTINE PERFUSION; JEJUNUM; NONHUMAN; RAT; SPRAGUE DAWLEY RAT; STATISTICAL SIGNIFICANCE;

ANIMALS; APIGENIN; CRATAEGUS; DIGOXIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLAVONOIDS; INTESTINAL ABSORPTION; MALE; P-GLYCOPROTEINS; PLANT LEAVES; RATS; RATS, SPRAGUE-DAWLEY; VERAPAMIL;

EID: 39849096862     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040701484668     Document Type: Article

References (36)