Resolution of inflammation: Mechanisms and opportunity for drug development

Pharmacology and Therapeutics

Volumn 139, Issue 2, 2013, Pages 189-212

  Alessandri, Ana L ^a   Sousa, Lirlândia P ^b   Lucas, Christopher D ^a   Rossi, Adriano G ^a   Pinho, Vanessa ^b   Teixeira, Mauro M ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Granulocyte apoptosis; Inflammation; Resolution; Signaling pathways; Tissue repair

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; AUTOPHAGY PROTEIN 5; BECLIN 1; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; CASPASE 9; CYCLIC AMP; DEXAMETHASONE; FAS ANTIGEN; FAS LIGAND; FRACTALKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOCORTIN 1; MONOCYTE CHEMOTACTIC PROTEIN 1; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TOLL LIKE RECEPTOR AGONIST; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; AUTOPHAGY; CELL DEATH; CELL MIGRATION; CELL SURVIVAL; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY; DRUG DESIGN; DRUG MECHANISM; ENDOTHELIUM CELL; GRANULOCYTE; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LEUKOCYTE; MACROPHAGE; MEDIATOR; MOLECULAR RECOGNITION; NEUTROPHIL; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DRUG DISCOVERY; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS;

EID: 84879413529     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.04.006     Document Type: Review

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