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Volumn 172, Issue 8, 2005, Pages 972-979

Defective apoptotic cell phagocytosis attenuates prostaglandin E 2 and 15-hydroxyeicosatetraenoic acid in severe asthma alveolar macrophages

Author keywords

Alveolar macrophages; Asthma; Lipopolysaccharide; Phagocytosis; Prostaglandin E2

Indexed keywords

15 HYDROXYICOSATETRAENOIC ACID; CORTICOSTEROID; DEXAMETHASONE; GRANULOCYTE COLONY STIMULATING FACTOR; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

EID: 26944476623     PISSN: 1073449X     EISSN: 1073449X     Source Type: Journal    
DOI: 10.1164/rccm.200501-035OC     Document Type: Article
Times cited : (131)

References (32)
  • 1
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 1998; 101:890-898.
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 2
    • 0036143018 scopus 로고    scopus 로고
    • Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation
    • Huynh ML, Fadok VA, Henson PM. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. J Clin Invest 2002;109:41-50.
    • (2002) J Clin Invest , vol.109 , pp. 41-50
    • Huynh, M.L.1    Fadok, V.A.2    Henson, P.M.3
  • 4
    • 0037184049 scopus 로고    scopus 로고
    • Activation of protein kinase C beta II by the stereo-specific phosphatidylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages
    • Todt JC, Hu B, Punturieri A, Sonstein J, Polak T, Curtis JL. Activation of protein kinase C beta II by the stereo-specific phosphatidylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages. J Biol Chem 2002;277:35906-35914.
    • (2002) J Biol Chem , vol.277 , pp. 35906-35914
    • Todt, J.C.1    Hu, B.2    Punturieri, A.3    Sonstein, J.4    Polak, T.5    Curtis, J.L.6
  • 5
    • 0036587746 scopus 로고    scopus 로고
    • Recognition and phagocytosis of apoptotic T cells by resident murine tissue macrophages require multiple signal transduction events
    • Hu B, Punturieri A, Todt J, Sonstein J, Polak T. Curtis JL. Recognition and phagocytosis of apoptotic T cells by resident murine tissue macrophages require multiple signal transduction events. J Leukoc Biol 2002; 71:881-889.
    • (2002) J Leukoc Biol , vol.71 , pp. 881-889
    • Hu, B.1    Punturieri, A.2    Todt, J.3    Sonstein, J.4    Polak, T.5    Curtis, J.L.6
  • 6
    • 0034663992 scopus 로고    scopus 로고
    • Deficient in vitro and in vivo phagocytosis of apoptotic T cells by resident murine alveolar macrophages
    • Hu B, Sonstein J, Christensen PJ, Punturieri A, Curtis JL. Deficient in vitro and in vivo phagocytosis of apoptotic T cells by resident murine alveolar macrophages. J Immunol 2000;165:2124-2133.
    • (2000) J Immunol , vol.165 , pp. 2124-2133
    • Hu, B.1    Sonstein, J.2    Christensen, P.J.3    Punturieri, A.4    Curtis, J.L.5
  • 7
    • 0035879302 scopus 로고    scopus 로고
    • Glucocorticoid augmentation of macrophage capacity for phagocytosis of apoptotic cells is associated with reduced p130Cas expression, loss of paxillin/pyk2 phosphorylation, and high levels of active Rac
    • Giles KM, Ross K, Rossi AG, Hotchin NA, Haslett C, Dransfield I. Glucocorticoid augmentation of macrophage capacity for phagocytosis of apoptotic cells is associated with reduced p130Cas expression, loss of paxillin/pyk2 phosphorylation, and high levels of active Rac. J Immunol 2001;167:976-986.
    • (2001) J Immunol , vol.167 , pp. 976-986
    • Giles, K.M.1    Ross, K.2    Rossi, A.G.3    Hotchin, N.A.4    Haslett, C.5    Dransfield, I.6
  • 8
    • 0034651737 scopus 로고    scopus 로고
    • Cutting edge: Lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages
    • Godson C, Mitchell S, Harvey K, Petasis NA, Hogg N, Brady HR. Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. J Immunol 2000;164:1663-1667.
    • (2000) J Immunol , vol.164 , pp. 1663-1667
    • Godson, C.1    Mitchell, S.2    Harvey, K.3    Petasis, N.A.4    Hogg, N.5    Brady, H.R.6
  • 9
    • 0036181314 scopus 로고    scopus 로고
    • The pathophysiology of asthma
    • Maddox L, Schwartz DA. The pathophysiology of asthma. Annu Rev Med 2002;53:477-498.
    • (2002) Annu Rev Med , vol.53 , pp. 477-498
    • Maddox, L.1    Schwartz, D.A.2
  • 10
    • 0032875377 scopus 로고    scopus 로고
    • Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
    • Wenzel SE, Schwartz LB, Langmack EL, Halliday JL, Trudeau JB, Gibbs RL, Chu HW. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999;160:1001-1008.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1001-1008
    • Wenzel, S.E.1    Schwartz, L.B.2    Langmack, E.L.3    Halliday, J.L.4    Trudeau, J.B.5    Gibbs, R.L.6    Chu, H.W.7
  • 11
    • 0030859389 scopus 로고    scopus 로고
    • Bronchoscopic evaluation of severe asthma: Persistent inflammation associated with high dose glucocorticoids
    • Wenzel SE, Szefler SJ, Leung DY, Sloan SI, Rex MD, Martin RJ. Bronchoscopic evaluation of severe asthma: persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med 1997; 156:737-743.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 737-743
    • Wenzel, S.E.1    Szefler, S.J.2    Leung, D.Y.3    Sloan, S.I.4    Rex, M.D.5    Martin, R.J.6
  • 12
    • 17844367104 scopus 로고    scopus 로고
    • Transforming growth factor-beta(1) secretion from murine macrophages is released by in vivo ingestion of apoptotic cells
    • Huynh ML, Fadok VA, Henson PM. Transforming growth factor-beta(1) secretion from murine macrophages is released by in vivo ingestion of apoptotic cells. Chest 2001;120:S3.
    • (2001) Chest , vol.120
    • Huynh, M.L.1    Fadok, V.A.2    Henson, P.M.3
  • 13
    • 0141791335 scopus 로고    scopus 로고
    • Surfactant protein a enhances apoptotic cell uptake and TGF-beta1 release by inflammatory alveolar macrophages
    • Reidy MF, Wright JR. Surfactant protein A enhances apoptotic cell uptake and TGF-beta1 release by inflammatory alveolar macrophages. Am J Physiol Lung Cell Mol Physiol 2003;285:L854-L861.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285
    • Reidy, M.F.1    Wright, J.R.2
  • 15
    • 0028363174 scopus 로고
    • Selective enhancement of GM-CSF, TNF-alpha, IL-1 beta and IL-8 production by monocytes and macrophages of asthmatic subjects
    • Hallsworth MP, Soh CP, Lane SJ, Arm JP, Lee TH. Selective enhancement of GM-CSF, TNF-alpha, IL-1 beta and IL-8 production by monocytes and macrophages of asthmatic subjects. Eur Respir J 1994;7:1096-1102.
    • (1994) Eur Respir J , vol.7 , pp. 1096-1102
    • Hallsworth, M.P.1    Soh, C.P.2    Lane, S.J.3    Arm, J.P.4    Lee, T.H.5
  • 17
    • 0041346077 scopus 로고    scopus 로고
    • Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells
    • Hodge S, Hodge G, Scicchitano R, Reynolds PN, Holmes M. Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunol Cell Biol 2003;81:289-296.
    • (2003) Immunol Cell Biol , vol.81 , pp. 289-296
    • Hodge, S.1    Hodge, G.2    Scicchitano, R.3    Reynolds, P.N.4    Holmes, M.5
  • 18
    • 0036434681 scopus 로고    scopus 로고
    • Expression and activation of 15-lipoxygenase pathway in severe asthma: Relationship to eosinophilic phenotype and collagen deposition
    • Chu HW, Balzar S, Westcott JY, Trudeau JB, Sun Y, Conrad DJ, Wenzel SE. Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition. Clin Exp Allergy 2002;32:1558-1565.
    • (2002) Clin Exp Allergy , vol.32 , pp. 1558-1565
    • Chu, H.W.1    Balzar, S.2    Westcott, J.Y.3    Trudeau, J.B.4    Sun, Y.5    Conrad, D.J.6    Wenzel, S.E.7
  • 21
    • 0346786463 scopus 로고    scopus 로고
    • Clearance of apoptotic cells: TGF-beta in the balance between inflammation and fibrosis
    • Clancy RM, Buyon JP. Clearance of apoptotic cells: TGF-beta in the balance between inflammation and fibrosis. J Leukoc Biol 2003;74:959-960.
    • (2003) J Leukoc Biol , vol.74 , pp. 959-960
    • Clancy, R.M.1    Buyon, J.P.2
  • 22
    • 0041427760 scopus 로고    scopus 로고
    • Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion
    • Lucas M, Stuart LM, Savill J, Lacy-Hulbert A. Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion. J Immunol 2003;171:2610-2615.
    • (2003) J Immunol , vol.171 , pp. 2610-2615
    • Lucas, M.1    Stuart, L.M.2    Savill, J.3    Lacy-Hulbert, A.4
  • 23
    • 0038162473 scopus 로고    scopus 로고
    • Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD)
    • Brown JR, Goldblatt D, Buddle J, Morton L, Thrasher AJ. Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD). J Leukoc Biol 2003;73:591-599.
    • (2003) J Leukoc Biol , vol.73 , pp. 591-599
    • Brown, J.R.1    Goldblatt, D.2    Buddle, J.3    Morton, L.4    Thrasher, A.J.5
  • 26
    • 0029885026 scopus 로고    scopus 로고
    • Decreased production of TGF-beta 1 by human alveolar macrophages compared with blood monocytes
    • Toossi Z, Hirsch CS, Hamilton BD, Knuth CK, Friedlander MA, Rich EA. Decreased production of TGF-beta 1 by human alveolar macrophages compared with blood monocytes. J Immunol 1996;156:3461-3468.
    • (1996) J Immunol , vol.156 , pp. 3461-3468
    • Toossi, Z.1    Hirsch, C.S.2    Hamilton, B.D.3    Knuth, C.K.4    Friedlander, M.A.5    Rich, E.A.6
  • 29
    • 0035018868 scopus 로고    scopus 로고
    • Association between airway hyperreactivity and bronchial macrophage dysfunction in individuals with mild asthma
    • Alexis NE, Soukup J, Nierkens S, Becker S. Association between airway hyperreactivity and bronchial macrophage dysfunction in individuals with mild asthma. Am J Physiol Lung Cell Mol Physiol 2001;280:L369-L375.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280
    • Alexis, N.E.1    Soukup, J.2    Nierkens, S.3    Becker, S.4
  • 30
    • 0043031375 scopus 로고    scopus 로고
    • Effect of inhaled endotoxin on airway and circulating inflammatory cell phagocytosis and CD11b expression in atopic asthmatic subjects
    • Alexis NE, Eldridge MW, Peden DB. Effect of inhaled endotoxin on airway and circulating inflammatory cell phagocytosis and CD11b expression in atopic asthmatic subjects. J Allergy Clin Immunol 2003;112: 353-361.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 353-361
    • Alexis, N.E.1    Eldridge, M.W.2    Peden, D.B.3
  • 31
    • 3042757394 scopus 로고    scopus 로고
    • Adoptive transfer of alveolar macrophages abrogates bronchial hyperresponsiveness
    • Careau E, Bissonnette EY. Adoptive transfer of alveolar macrophages abrogates bronchial hyperresponsiveness. Am J Respir Cell Mol Biol 2004;31:22-27.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 22-27
    • Careau, E.1    Bissonnette, E.Y.2
  • 32
    • 3042838551 scopus 로고    scopus 로고
    • The alveolar macrophage: The forgotten cell in asthma
    • Peters-Golden M. The alveolar macrophage: the forgotten cell in asthma. Am J Respir Cell Mol Biol 2004;31:3-7.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 3-7
    • Peters-Golden, M.1


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