Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1

British Journal of Pharmacology

Volumn 120, Issue 6, 1997, Pages 1075-1082

  Getting, Stephen J ^a   Flower, Roderick J ^a   Perretti, Mauro ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Annexin I; Dexamethasone; Extravasation; Inflammation; Macrophage

Indexed keywords

DEXAMETHASONE; LIPOCORTIN 1; PEPTIDE; POLYCLONAL ANTIBODY; VINBLASTINE; ZYMOSAN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; DOSE RESPONSE; FLOW CYTOMETRY; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE ACTIVATION; LEUKOPENIA; MALE; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PASSIVE IMMUNIZATION; PERITONEAL CAVITY; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030955133     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701029     Document Type: Article

References (25)

1. BERRY, D.A. & LINDGREN, B.W. (1990). Statistics: Theory and Methods, p.650. Pacific Grove, CA: Brooks/Cole Publishing Company.
2. BLACKWELL, G.J., CARNUCCIO, R., DI ROSA, M., FLOWER, R.J., PARENTE, L. & PERSICO, P. (1980). Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids. Nature, 287, 147-149.
3. CASSATELLA, M.A. (1995). The production of cytokines by polymorphonuclear neutrophils. Immunol. Today, 16, 21-26.
4. COMÉRA, C. & RUSSO-MARIE, F. (1995). Glucocorticoid-induced annexin 1 secretion by monocytes and peritoneal leukocytes. Br. J. Pharmacol., 115, 1043-1047.
5. DE CATERINA, R., SICARI, R., GIANNESSI, D., PAGGIARO, P.L., PAOLETTI, P., LAZZERINI, G., BERNINI, W., SOLITO, E. & PARENTE, L. (1993). Macrophage-specific eicosanoid synthesis inhibition and lipocortin-1 induction by glucocorticoids. J. Appl. Physiol., 75, 2368-2375.
6. FLOWER, R.J. & ROTHWELL, N.J. (1994). Lipocortin-1: cellular mechanisms and clinical relevance. Trends Pharmacol. Sci., 15, 71-76.
7. GOULDING, N.J., GODOLPHIN, J.L., SHARLAND, P.R., PEERS, S.H., SAMPSON, M., MADDISON, P.J. & FLOWER, R.J. (1990). Antiinflammatory lipocortin 1 production by peripheral blood leucocytes in response to hydrocortisone. Lancet, 335, 1416-1418.
8. GOULDING, N.J., PAN, L., WARDWELL, K., GUYRE, V.C. & GUYRE, P.M. (1996). Evidence for specific annexin I-binding proteins on human monocytes. Biochem. J., 316, 593-597.
9. IWAMURA, H., MOORE, A. & WILLOUGHBY, D.A. (1993). Interaction between neutrophil-derived elastase and reactive oxygen species in cartilage degradation. Biochim. Biophys. Acta, 1156, 295-301.
10. KLEMM, P., HARRIS, H.J. & PERRETTI, M. (1995). Effect of rolipram in a murine model of acute inflammation: comparison with the corticoid dexamethasone. Eur. J. Pharmacol., 281, 69-74.
11. MANCUSO, F., FLOWER, R.J. & PERRETTI, M. (1995). Leukocyte transmigration, but not rolling or adhesion, is selectively inhibited by dexamethasone in the hamster post-capillary venule. Involvement of endogenous lipocortin 1. J. Immunol., 155, 377-386.
12. 2 generation by dexamethasone is mimicked by lipocortin 1 in alveolar macrophages. J. Clin. Invest., 83, 1936-1940.
13. MIOTLA, J.M., PERRETTI, M., FLOWER, R.J., JEFFERY, P.K. & HELLEWELL, P.G. (1995). Suppresion of experimental acute lung injury in the mouse by dexamethasone and the role of lipocortin-1. Br. J. Pharmacol., 114, 62P.
14. PERRETTI, M. (1994). Lipocortin-derived peptides. Biochem. Pharmacol., 47, 931-938.
15. PERRETTI, M., AHLUWALIA, A., HARRIS, J.G., GOULDING, N.J. & FLOWER, R.J. (1993). Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse: a qualitative comparison with an anti-CD11b monoclonal antibody. J. Immunol., 151, 4306-4314.
16. PERRETTI, M., AHLUWALIA, A., HARRIS, J.G., HARRIS, H.J., WHELLER, S.K. & FLOWER, R.J. (1996a). Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1. Br. J. Pharmacol., 117, 1145-1154.
17. PERRETTI, M., CROXTALL, J.D., WHELLER, S.K., GOULDING, N.J., HANNON, R. & FLOWER, R.J. (1996b). Mobilisation of lipocortin 1 in adherent human polymorphonuclear leukocytes negatively modulates their transmigration. Nature Med., 2, 1259-1262.
18. PERRETTI, M. & FLOWER, R.J. (1993). Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1. J. Immunol., 150, 992-999.
19. PERRETTI, M. & FLOWER, R.J. (1996). Measurement of lipocortin 1 levels in murine peripheral blood leukocytes by flow cytometry: modulation by glucocorticoids and inflammation. Br. J. Pharmacol., 118, 605-610.
20. PERRETTI, M., SOLITO, E. & PARENTE, L. (1992). Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice. Agents Actions, 35, 71-78.
21. RUSSO-MARIE, F. (1992). Macrophages and the glucocorticoids. J. Neuroimmunol., 40, 281-296.
22. SOLITO, E., RAUGEI, G., MELLI, M. & PARENTE, L. (1991). Dexamethasone induces the expression of the mRNA of lipocortin 1 and 2 and the release of lipocortin 1 and 5 in differentiated, but not undifferentiated U-937 cells. FEBS Lett., 291, 238-244.
23. 2 and TNFα release from human peripheral blood mononuclear cells. Br. J. Pharmacol., 117, 1449-1456.
24. TAPPER, H. (1996). The secretion of preformed granules by macrophages and neutrophils. J. Leukoc. Biol., 59, 613-622.
25. WEBB, Z. (1979). Biochemical actions of glucocorticoids on macrophage in culture. Specific inhibition of elastase, collagenase, and plasminogen activator secretion and effects on other metabolic functions. J. Exp. Med., 147, 1695-1711.