Cyclin-dependent kinases 7 and 9 specifically regulate neutrophil transcription and their inhibition drives apoptosis to promote resolution of inflammation

Cell Death and Differentiation

Volumn 19, Issue 12, 2012, Pages 1950-1961

  Leitch, A E ^a   Lucas, C D ^a   Marwick, J A ^a   Duffin, R ^a   Haslett, C ^a   Rossi, A G ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

apoptosis; cyclin dependent kinase; inflammation; neutrophil; resolution

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; CASPASE 9; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 7; CYCLIN DEPENDENT KINASE 9; DACTINOMYCIN; HISTONE H3; PROTEIN BID; RNA POLYMERASE II; ROSCOVITINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; LUNG INJURY; MICROARRAY ANALYSIS; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

APOPTOSIS; CYCLIN-DEPENDENT KINASE 9; CYCLIN-DEPENDENT KINASES; DICHLORORIBOFURANOSYLBENZIMIDAZOLE; HEP G2 CELLS; HL-60 CELLS; HUMANS; INFLAMMATION; NEUTROPHILS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PURINES; RNA POLYMERASE II; TRANSCRIPTION, GENETIC;

EID: 84869082844     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.80     Document Type: Article

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