The melanocortin agonist AP214 exerts anti-inflammatory and proresolving properties

American Journal of Pathology

Volumn 179, Issue 1, 2011, Pages 259-269

  Montero Melendez, Trinidad ^a   Patel, Hetal B ^a   Seed, Michael ^a   Nielsen, Søren ^b,c   Jonassen, Thomas E N ^c,d   Perretti, Mauro ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b AARHUS UNIVERSITY   (Denmark)

^c Action Pharma   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; AP 214; INTERLEUKIN 1BETA; INTERLEUKIN 6; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN RECEPTOR AGONIST; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; EFFEROCYTOSIS; HUMAN; HUMAN CELL; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; PERITONITIS; PHAGOCYTOSIS; PRIORITY JOURNAL;

ALPHA-MSH; ANIMALS; APOPTOSIS; ARTHRITIS, EXPERIMENTAL; BLOTTING, WESTERN; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MACROPHAGES; MACROPHAGES, PERITONEAL; MALE; MELANOCORTINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; NEUTROPHILS; PERITONITIS; PHAGOCYTOSIS; RECEPTOR, MELANOCORTIN, TYPE 1; RECEPTOR, MELANOCORTIN, TYPE 3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80052445254     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.03.042     Document Type: Article

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