Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase

Nature

Volumn 403, Issue 6765, 2000, Pages 103-108

  Rossi, Antonio ^a   Kapahi, Pankaj ^c   Natoli, Gloacchino ^c   Takahashi, Takayuki ^c   Chen, Yi ^c   Karin, Michael ^c   Santoro, M Gabriella ^a,b  

^a CNR   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; CYCLOPENTENONE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN KAPPA CHAIN; PROSTAGLANDIN; PROSTAGLANDIN E; UBIQUITIN;

ARTICLE; CONJUGATION; DEGRADATION; IMMUNITY; INFLAMMATION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONIC ACID; COS CELLS; CYCLOPENTANES; ENZYME ACTIVATION; ENZYME INHIBITORS; HELA CELLS; HUMANS; I-KAPPA B KINASE; JURKAT CELLS; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROSTAGLANDIN D2; PROSTAGLANDINS A; PROTEIN-SERINE-THREONINE KINASES; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034610759     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/47520     Document Type: Article

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