Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 40, 2005, Pages 14238-14243

  Nobukuni, Takahiro ^a,b   Joaquin, Manel ^a,b   Roccio, Marta ^c   Dann, Stephen G ^b   Kim, So Young ^a   Gulati, Pawan ^b   Byfield, Maya P ^d   Backer, Jonathan M ^d   Natt, Francois ^e   Bos, Johannes L ^c   Zwartkruis, Fried J T ^c   Thomas, George ^a,b  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b UNIVERSITY OF CINCINNATI   (United States)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

56 Kinase 1; Endosomes; Insulin; Nutrients; PI3P

Indexed keywords

AMINO ACID; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE;

AMINO ACID TRANSPORT; ARTICLE; CONTROLLED STUDY; DEVELOPMENT; ENZYME ACTIVATION; ENZYME ACTIVITY; EVOLUTION; GROWTH; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACIDS; BLOTTING, WESTERN; CELL LINE, TUMOR; HUMANS; MICROSCOPY, FLUORESCENCE; MONOMERIC GTP-BINDING PROTEINS; NEUROPEPTIDES; PROTEIN KINASES; PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

MAMMALIA; METAZOA;

EID: 26444575415     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0506925102     Document Type: Article

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