메뉴 건너뛰기




Volumn 303, Issue 4, 2003, Pages 1047-1052

Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids

Author keywords

Acetate; Cell surface receptor; Fatty acid; GPCR; GPR43; Immune system; Pertussis toxin; PMNC; Propionate; SCFA

Indexed keywords

ACETIC ACID; BUTYRIC ACID; CALCIUM; CELL SURFACE RECEPTOR; FORMIC ACID; G PROTEIN COUPLED RECEPTOR; LIGAND; PROPIONIC ACID; SHORT CHAIN FATTY ACID; VALERIC ACID;

EID: 0037453280     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00488-1     Document Type: Article
Times cited : (457)

References (29)
  • 1
    • 0030137324 scopus 로고    scopus 로고
    • The correlation between an increase in subgingival temperature and the concentration of volatile fatty acids of bacterial origin present in periodontal pockets
    • Eftimiadi C., Blasi G. The correlation between an increase in subgingival temperature and the concentration of volatile fatty acids of bacterial origin present in periodontal pockets. Minerva Stomatol. 45:1996;189-196.
    • (1996) Minerva Stomatol. , vol.45 , pp. 189-196
    • Eftimiadi, C.1    Blasi, G.2
  • 2
    • 0023147138 scopus 로고
    • Short-chain fatty acids produced by anaerobic bacteria alter the physiological responses of human neutrophils to chemotactic peptide
    • Eftimiadi C., Buzzi E., Tonetti M., Buffa P., Buffa D., van Steenbergen M.T., de Graaff J., Botta G.A. Short-chain fatty acids produced by anaerobic bacteria alter the physiological responses of human neutrophils to chemotactic peptide. J. Infect. 14:1987;43-53.
    • (1987) J. Infect. , vol.14 , pp. 43-53
    • Eftimiadi, C.1    Buzzi, E.2    Tonetti, M.3    Buffa, P.4    Buffa, D.5    Van Steenbergen, M.T.6    De Graaff, J.7    Botta, G.A.8
  • 3
    • 0032900260 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated proliferation of human peripheral lymphocytes in vitro by propionic acid
    • Wajner M., Santos K.D., Schlottfeldt J.L., Rocha M.P., Wannmacher C.M. Inhibition of mitogen-activated proliferation of human peripheral lymphocytes in vitro by propionic acid. Clin. Sci. (Lond.). 96:1999;99-103.
    • (1999) Clin. Sci. (Lond.) , vol.96 , pp. 99-103
    • Wajner, M.1    Santos, K.D.2    Schlottfeldt, J.L.3    Rocha, M.P.4    Wannmacher, C.M.5
  • 5
    • 0027155652 scopus 로고
    • Interactions between leukocytes and anaerobic bacteria in polymicrobial surgical infections
    • Rotstein O.D. Interactions between leukocytes and anaerobic bacteria in polymicrobial surgical infections. Clin. Infect. Dis. 16(Suppl. 4):1993;S190-194.
    • (1993) Clin. Infect. Dis. , vol.16 , Issue.SUPPL. 4 , pp. 190-194
    • Rotstein, O.D.1
  • 6
    • 0026633897 scopus 로고
    • Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl-leucyl-phenylalanine-stimulated activation
    • Brunkhorst B.A., Kraus E., Coppi M., Budnick M., Niederman R. Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl-leucyl-phenylalanine-stimulated activation. Infect. Immun. 60:1992;2957-2968.
    • (1992) Infect. Immun. , vol.60 , pp. 2957-2968
    • Brunkhorst, B.A.1    Kraus, E.2    Coppi, M.3    Budnick, M.4    Niederman, R.5
  • 7
    • 0026614980 scopus 로고
    • 2+ in resting and stimulated human neutrophils by short-chain carboxylic acids at neutral pH
    • 2+ in resting and stimulated human neutrophils by short-chain carboxylic acids at neutral pH Infect. Immun. 60:1992;5307-5311.
    • (1992) Infect. Immun. , vol.60 , pp. 5307-5311
    • Nakao, S.1    Fujii, A.2    Niederman, R.3
  • 8
    • 0035430933 scopus 로고    scopus 로고
    • Short-chain carboxylic acids produced by gram-negative anaerobic bacteria can accelerate or delay polymorphonuclear leukocyte apoptosis in vitro
    • Stehle H.W., Leblebicioglu B., Walters J.D. Short-chain carboxylic acids produced by gram-negative anaerobic bacteria can accelerate or delay polymorphonuclear leukocyte apoptosis in vitro. J. Periodontol. 72:2001;1059-1063.
    • (2001) J. Periodontol. , vol.72 , pp. 1059-1063
    • Stehle, H.W.1    Leblebicioglu, B.2    Walters, J.D.3
  • 11
    • 0029693922 scopus 로고    scopus 로고
    • Short-chain fatty acids in the human colon: Relation to gastrointestinal health and disease
    • Mortensen P.B., Clausen M.R. Short-chain fatty acids in the human colon: relation to gastrointestinal health and disease. Scand. J. Gastroenterol. Suppl. 216:1996;132-148.
    • (1996) Scand. J. Gastroenterol. Suppl. , vol.216 , pp. 132-148
    • Mortensen, P.B.1    Clausen, M.R.2
  • 12
    • 0035843993 scopus 로고    scopus 로고
    • Commensal host-bacterial relationships in the gut
    • Hooper L.V., Gordon J.I. Commensal host-bacterial relationships in the gut. Science. 292:2001;1115-1118.
    • (2001) Science , vol.292 , pp. 1115-1118
    • Hooper, L.V.1    Gordon, J.I.2
  • 14
    • 0035666950 scopus 로고    scopus 로고
    • Nutritional factors and immune functions of gut epithelium
    • Sanderson I.R. Nutritional factors and immune functions of gut epithelium. Proc. Nutr. Soc. 60:2001;443-447.
    • (2001) Proc. Nutr. Soc. , vol.60 , pp. 443-447
    • Sanderson, I.R.1
  • 15
    • 0037093355 scopus 로고    scopus 로고
    • Short-chain fatty acids: Bacterial mediators of a balanced host-microbial relationship in the human gut
    • Saemann M.D., Bohmig G.A., Zlabinger G.J. Short-chain fatty acids: bacterial mediators of a balanced host-microbial relationship in the human gut. Wien. Klin. Wochenschr. 114:2002;289-300.
    • (2002) Wien. Klin. Wochenschr. , vol.114 , pp. 289-300
    • Saemann, M.D.1    Bohmig, G.A.2    Zlabinger, G.J.3
  • 17
  • 18
    • 0035863914 scopus 로고    scopus 로고
    • A chimeric reporter gene allowing for clone selection and high-throughput screening of reporter cell lines expressing G-protein-coupled receptors
    • Kotarsky K., Owman C., Olde B. A chimeric reporter gene allowing for clone selection and high-throughput screening of reporter cell lines expressing G-protein-coupled receptors. Anal. Biochem. 288:2001;209-215.
    • (2001) Anal. Biochem. , vol.288 , pp. 209-215
    • Kotarsky, K.1    Owman, C.2    Olde, B.3
  • 19
    • 0037447842 scopus 로고    scopus 로고
    • Optimized reporter gene assays based on a synthetic multifunctional promoter and a secreted luciferase
    • in press
    • K. Kotarsky, L. Antonsson, C. Owman, B. Olde, Optimized reporter gene assays based on a synthetic multifunctional promoter and a secreted luciferase, Anal. Biochem. (2003) in press.
    • (2003) Anal. Biochem.
    • Kotarsky, K.1    Antonsson, L.2    Owman, C.3    Olde, B.4
  • 22
    • 0035910270 scopus 로고    scopus 로고
    • Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
    • Krogh A., Larsson B., von Heijne G., Sonnhammer E.L. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305:2001;567-580.
    • (2001) J. Mol. Biol. , vol.305 , pp. 567-580
    • Krogh, A.1    Larsson, B.2    Von Heijne, G.3    Sonnhammer, E.L.4
  • 23
    • 0031581088 scopus 로고    scopus 로고
    • A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1
    • Sawzdargo M., George S.R., Nguyen T., Xu S., Kolakowski L.F., O'Dowd B.F. A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1. Biochem. Biophys. Res. Commun. 239:1997;543-547.
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 543-547
    • Sawzdargo, M.1    George, S.R.2    Nguyen, T.3    Xu, S.4    Kolakowski, L.F.5    O'Dowd, B.F.6
  • 24
    • 0023805092 scopus 로고
    • Propionic acid-induced calcium mobilization in human neutrophils
    • Naccache P.H., Faucher N., Caon A.C., McColl S.R. Propionic acid-induced calcium mobilization in human neutrophils. J. Cell. Physiol. 136:1988;118-124.
    • (1988) J. Cell. Physiol. , vol.136 , pp. 118-124
    • Naccache, P.H.1    Faucher, N.2    Caon, A.C.3    McColl, S.R.4
  • 25
    • 0030834273 scopus 로고    scopus 로고
    • Short-chain carboxylic-acid-stimulated, PMN-mediated gingival inflammation
    • Niederman R., Zhang J., Kashket S. Short-chain carboxylic-acid-stimulated, PMN-mediated gingival inflammation. Crit. Rev. Oral Biol. Med. 8:1997;269-290.
    • (1997) Crit. Rev. Oral Biol. Med. , vol.8 , pp. 269-290
    • Niederman, R.1    Zhang, J.2    Kashket, S.3
  • 27
    • 0021349954 scopus 로고
    • Gas-liquid chromatography for rapid diagnosis of intra-abdominal infection
    • Spiegel C.A., Malangoni M.A., Condon R.E. Gas-liquid chromatography for rapid diagnosis of intra-abdominal infection. Arch. Surg. 119:1984;28-32.
    • (1984) Arch. Surg. , vol.119 , pp. 28-32
    • Spiegel, C.A.1    Malangoni, M.A.2    Condon, R.E.3
  • 29
    • 0032581102 scopus 로고    scopus 로고
    • Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats
    • Johansson M.L., Nobaek S., Berggren A., Nyman M., Bjorck I., Ahrne S., Jeppsson B., Molin G. Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats. Int. J. Food Microbiol. 42:1998;29-38.
    • (1998) Int. J. Food Microbiol. , vol.42 , pp. 29-38
    • Johansson, M.L.1    Nobaek, S.2    Berggren, A.3    Nyman, M.4    Bjorck, I.5    Ahrne, S.6    Jeppsson, B.7    Molin, G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.