Inhibition of caspase-dependent spontaneous apoptosis via a cAMP-protein kinase a dependent pathway in neutrophils from sickle cell disease patients

British Journal of Haematology

Volumn 139, Issue 1, 2007, Pages 148-158

  Conran, Nicola ^a   Almeida, Camila B ^a   Lanaro, Carolina ^a   Ferreira, Renata Proença ^a   Traina, Fabiola ^a   Saad, Sara T O ^a   Costa, Fernando F ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Apoptosis; Caspase; Leucocyte; Sickle cell disease; Signalling

Indexed keywords

CASPASE; CASPASE 3; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROXYUREA; INHIBITOR OF APOPTOSIS PROTEIN; INTERLEUKIN 8; KT 5720; PROSTAGLANDIN; PROTEIN BAX; PROTEIN BIRC2; PROTEIN BIRC3; PROTEIN MCL 1; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; IN VIVO CULTURE; INCUBATION TIME; INFLAMMATORY CELL; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; SICKLE CELL ANEMIA;

ADULT; ANEMIA, SICKLE CELL; ANNEXIN A5; ANTISICKLING AGENTS; APOPTOSIS; BIOLOGICAL MARKERS; CARBAZOLES; CASE-CONTROL STUDIES; CASPASE 3; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HUMANS; HYDROXYUREA; INDOLES; MALE; NEUTROPHILS; PROSTAGLANDINS E; PYRROLES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 34548550706     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2007.06748.x     Document Type: Article

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