Effects of melanocortin peptides on lipopolysaccharide/interferon-gamma-induced NF-kappaB DNA binding and nitric oxide production in macrophage-like RAW 264.7 cells: Evidence for dual mechanisms of action

Biochemical Pharmacology

Volumn 61, Issue 5, 2001, Pages 613-621

  Mandrika, Ilona ^a   Muceniece, Ruta ^a   Wikberg, Jarl E S ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

cAMP; Inflammation; Macrophages; Melanocortin peptides; NF B; Nitric oxide

Indexed keywords

ALPHA INTERMEDIN; BACTERIUM LIPOPOLYSACCHARIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; FORSKOLIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MELANOCORTIN RECEPTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NITRIC OXIDE; PROOPIOMELANOCORTIN; RADIOLIGAND;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL STIMULATION; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; HORMONE RECEPTOR INTERACTION; IC 50; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACTIVE TRANSPORT, CELL NUCLEUS; ALPHA-MSH; ANIMALS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA; DRUG INTERACTIONS; ENZYME INHIBITORS; FORSKOLIN; GENES, REPORTER; INTERFERON TYPE II; ISOQUINOLINES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; NITRITES; PEPTIDES; RECEPTORS, CORTICOTROPIN; RECEPTORS, MELANOCORTIN; SULFONAMIDES;

EID: 0035282828     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00583-9     Document Type: Article

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