Inhibition of NF-κ-dependent transcription by MKP-1. Transcriptional repression by glucocorticoids occuring via p38 MAPK

Journal of Biological Chemistry

Volumn 284, Issue 39, 2009, Pages 26803-26815

  King, Elizabeth M ^a   Holden, Neil S ^a   Gong, Wei ^a   Rider, Christopher F ^a   Newton, Robert ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY EFFECTS; DEXAMETHASONES; GENE SYNTHESIS; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOIDS; INFLAMMATORY GENES; MAPK KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE; P38 MAPK; SMALL INTERFERING RNA; TRANSACTIVATION; TRANSCRIPTIONAL ACTIVATIONS; TRANSCRIPTIONAL REPRESSION;

CHEMICAL ACTIVATION; DRUG PRODUCTS; NUCLEIC ACIDS; PHOSPHORYLATION; RNA;

TRANSCRIPTION;

DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; CYCLOHEXIMIDE; DACTINOMYCIN; DUSP1 PROTEIN, HUMAN; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE REPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA SPLICING; RNA TRANSCRIPTION; RNA TRANSLATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; CELL LINE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CYCLOHEXIMIDE; DACTINOMYCIN; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DUAL SPECIFICITY PHOSPHATASE 1; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; IMIDAZOLES; INTERLEUKIN-8; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PYRIDINES; PYRIMIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70350351542     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.028381     Document Type: Article

References (58)

1. Barnes, P. J. (2008) Nat. Rev. Immunol. 8, 183-192
2. De Bosscher, K., Vanden Berghe, W., and Haegeman, G. (2003) Endocr. Rev. 24, 488-522
3. Karin, M., and Delhase, M. (2000) Semin. Immunol. 12, 85-98
4. Karin, M., and Ben-Neriah, Y. (2000) Annu. Rev. Immunol. 18, 621-663
5. Catley, M. C., Chivers, J. E., Holden, N. S., Barnes, P. J., and Newton, R. (2005) Br. J. Pharmacol. 145, 114-122
6. Newton, R., Holden, N. S., Catley, M. C., Oyelusi, W., Leigh, R., Proud, D., and Barnes, P. J. (2007) J. Pharmacol. Exp. Ther. 321, 734-742
7. Newton, R., and Holden, N. S. (2007) Mol. Pharmacol. 72, 799-809
8. De Bosscher, K., and Haegeman, G. (2009) Mol. Endocrinol. 23, 281-291
9. De Bosscher, K., Schmitz, M. L., Vanden Berghe, W., Plaisance, S., Fiers, W., and Haegeman, G. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 13504-13509
10. Scheinman, R. I., Gualberto, A., Jewell, C. M., Cidlowski, J. A., and Baldwin, A. S., Jr. (1995) Mol. Cell Biol. 15, 943-953
11. Ito, K., Barnes, P. J., and Adcock, I. M. (2000) Mol. Cell Biol. 20, 6891-6903
12. Ito, K., Jazrawi, E., Cosio, B., Barnes, P. J., and Adcock, I. M. (2001) J. Biol. Chem. 276, 30208-30215
13. Schmitz, M. L., Mattioli, I., Buss, H., and Kracht, M. (2004) ChemBioChem 5, 1348-1358
14. Beyaert, R., Cuenda, A., Vanden Berghe, W., Plaisance, S., Lee, J. C., Haegeman, G., Cohen, P., and Fiers, W. (1996) EMBO J. 15, 1914-1923
15. Catley, M. C., Cambridge, L. M., Nasuhara, Y., Ito, K., Chivers, J. E., Beaton, A., Holden, N. S., Bergmann, M. W., Barnes, P. J., and Newton, R. (2004) J. Biol. Chem. 279, 18457-18466
16. Kyriakis, J. M., and Avruch, J. (2001) Physiol. Rev. 81, 807-869
17. Vanden Berghe, W., Plaisance, S., Boone, E., De Bosscher, K., Schmitz, M. L., Fiers, W., and Haegeman, G. (1998) J. Biol. Chem. 273, 3285-3290
18. Ghosh, S., and Hayden, M. S. (2008) Nat. Rev. Immunol. 8, 837-848
19. Newton, R., and Holden, N. S. (2006) Drug Discov. Today Dis. Mech. 3, 53-61
20. Vermeulen, L., De Wilde, G., Van Damme, P., Vanden Berghe, W., and Haegeman, G. (2003) EMBO J. 22, 1313-1324
21. Reber, L., Vermeulen, L., Haegeman, G., and Frossard, N. (2009) PLoS ONE 4, e4393
22. Bratton, M. R., Frigo, D. E., Vigh-Conrad, K. A., Fan, D., Wadsworth, S., McLachlan, J. A., and Burow, M. E. (2009) Carcinogenesis 30, 106-113
23. Saha, R. N., Jana, M., and Pahan, K. (2007) J. Immunol. 179, 7101-7109
24. Saccani, S., Pantano, S., and Natoli, G. (2002) Nat. Immunol. 3, 69-75
25. Carter, A. B., Knudtson, K. L., Monick, M. M., and Hunninghake, G. W. (1999) J. Biol. Chem. 274, 30858-30863
26. Clark, A. R., Martins, J. R., and Tchen, C. R. (2008) J. Biol. Chem. 283, 25765-25769
27. Kassel, O., Sancono, A., Krätzschmar, J., Kreft, B., Stassen, M., and Cato, A. C. (2001) EMBO J. 20, 7108-7116
28. Lasa, M., Abraham, S. M., Boucheron, C., Saklatvala, J., and Clark, A. R. (2002) Mol. Cell Biol. 22, 7802-7811
29. Abraham, S. M., Lawrence, T., Kleiman, A., Warden, P., Medghalchi, M., Tuckermann, J., Saklatvala, J., and Clark, A. R. (2006) J. Exp. Med. 203, 1883-1889
30. Kang, B. N., Jude, J. A., Panettieri, R. A., Jr., Walseth, T. F., and Kannan, M. S. (2008) Am. J. Physiol. Lung Cell Mol. Physiol 295, L186-L193
31. Issa, R., Xie, S., Khorasani, N., Sukkar, M., Adcock, I. M., Lee, K. Y., and Chung, K. F. (2007) J. Immunol. 178, 7366-7375
32. Quante, T., Ng, Y. C., Ramsay, E. E., Henness, S., Allen, J. C., Parmentier, J., Ge, Q., and Ammit, A. J. (2008) Am. J. Respir. Cell Mol. Biol. 39, 208-217
33. Chivers, J. E., Gong, W., King, E. M., Seybold, J., Mak, J. C., Donnelly, L. E., Holden, N. S., and Newton, R. (2006) Mol. Pharmacol. 70, 2084-2095
34. Holden, N. S., Gong, W., King, E. M., Kaur, M., Giembycz, M. A., and Newton, R. (2007) Br. J. Pharmacol. 152, 891-902
35. Lipson, K. E., and Baserga, R. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 9774-9777
36. Bueno, O. F., De Windt, L. J., Lim, H. W., Tymitz, K. M., Witt, S. A., Kimball, T. R., and Molkentin, J. D. (2001) Circ. Res. 88, 88-96
37. Kaiser, R. A., Bueno, O. F., Lips, D. J., Doevendans, P. A., Jones, F., Kimball, T. F., and Molkentin, J. D. (2004) J. Biol. Chem. 279, 15524-15530
38. Tudhope, S. J., Catley, M. C., Fenwick, P. S., Russell, R. E., Rumsey, W. L., Newton, R., Barnes, P. J., and Donnelly, L. E. (2007) J. Immunol. 179, 6237-6245
39. Cuenda, A., Rouse, J., Doza, Y. N., Meier, R., Cohen, P., Gallagher, T. F., Young, P. R., and Lee, J. C. (1995) FEBS Lett. 364, 229-233
40. Underwood, D. C., Osborn, R. R., Bochnowicz, S., Webb, E. F., Rieman, D. J., Lee, J. C., Romanic, A. M., Adams, J. L., Hay, D. W., and Griswold, D. E. (2000) Am. J. Physiol. Lung Cell Mol. Physiol 279, L895-L902
41. Newton, R., Stevens, D. A., Hart, L. A., Lindsay, M., Adcock, I. M., and Barnes, P. J. (1997) FEBS Lett. 418, 135-138
42. Chivers, J. E., Cambridge, L. M., Catley, M. C., Mak, J. C., Donnelly, L. E., Barnes, P. J., and Newton, R. (2004) Eur. J. Biochem. 271, 4042-4052
43. Newton, R., Seybold, J., Kuitert, L. M., Bergmann, M., and Barnes, P. J. (1998) J. Biol. Chem. 273, 32312-32321
44. Bergmann, M., Hart, L., Lindsay, M., Barnes, P. J., and Newton, R. (1998) J. Biol. Chem. 273, 6607-6610
45. Newton, R., Hart, L. A., Stevens, D. A., Bergmann, M., Donnelly, L. E., Adcock, I. M., and Barnes, P. J. (1998) Eur. J. Biochem. 254, 81-89
46. Nissen, R. M., and Yamamoto, K. R. (2000) Genes Dev. 14, 2314-2329
47. Beck, I. M., Vanden Berghe, W., Vermeulen, L., Bougarne, N., Vander Cruyssen, B., Haegeman, G., and De Bosscher, K. (2008) EMBO J. 27, 1682-1693
48. Kaur, M., Chivers, J. E., Giembycz, M. A., and Newton, R. (2008) Mol. Pharmacol. 73, 203-214
49. Ayroldi, E., Migliorati, G., Bruscoli, S., Marchetti, C., Zollo, O., Cannarile, L., D'Adamio, F., and Riccardi, C. (2001) Blood 98, 743-753
50. Eddleston, J., Herschbach, J., Wagelie-Steffen, A. L., Christiansen, S. C., and Zuraw, B. L. (2007) J. Allergy Clin. Immunol. 119, 115-122
51. Uings, I. J., and Farrow, S. N. (2005) Curr. Opin. Pharmacol. 5, 221-226
52. Diefenbacher, M., Sekula, S., Heilbock, C., Maier, J. V., Litfin, M., van Dam, H., Castellazzi, M., Herrlich, P., and Kassel, O. (2008) Mol. Endocrinol. 22, 1767-1780
53. Cho, I. J., and Kim, S. G. (2009) Mol. Endocrinol. 23, 86-99
54. Vayssière, B. M., Dupont, S., Choquart, A., Petit, F., Garcia, T., Marchandeau, C., Gronemeyer, H., and Resche-Rigon, M. (1997) Mol. Endocrinol. 11, 1245-1255
55. Reichardt, H. M., Kaestner, K. H., Tuckermann, J., Kretz, O., Wessely, O., Bock, R., Gass, P., Schmid, W., Herrlich, P., Angel, P., and Schütz, G. (1998) Cell 93, 531-541
56. Reichardt, H. M., Tuckermann, J. P., Göttlicher, M., Vujic, M., Weih, F., Angel, P., Herrlich, P., and Schütz, G. (2001) EMBO J. 20, 7168-7173
57. Jonat, C., Rahmsdorf, H. J., Park, K. K., Cato, A. C., Gebel, S., Ponta, H., and Herrlich, P. (1990) Cell 62, 1189-1204
58. Simons, S. S., Jr. (2006) Curr. Top. Med. Chem. 6, 271-285