Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF

Journal of Clinical Investigation

Volumn 101, Issue 4, 1998, Pages 890-898

  Fadok, Valerie A ^a   Bratton, Donna L ^a   Konowal, Anatole ^a   Freed, Peter W ^a   Westcott, Jay Y ^a   Henson, Peter M ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

Apoptosis; Eicosanoids; Inflammation; Mediators; Phagocytosis

Indexed keywords

ANTIBODY; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN G; INDOMETACIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 8; LEUKOTRIENE C4; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROSTAGLANDIN D2; PROSTAGLANDIN E2; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOXANE B2; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ELECTRON MICROSCOPY; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MICROSCOPY; NEUTROPHIL; PHAGOCYTOSIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032519925     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1112     Document Type: Article

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