Annexin-1 regulates macrophage IL-6 and TNF via glucocorticoid-induced leucine zipper

Journal of Immunology

Volumn 183, Issue 2, 2009, Pages 1435-1445

  Yang, Yuan H ^a   Aeberli, Daniel ^a   Dacumos, April ^a   Xue, Jin R ^a   Morand, Eric F ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID INDUCED LEUCINE ZIPPER PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LEUCINE ZIPPER PROTEIN; LIPOCORTIN 1; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYTOKINE; DSIP1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; MACROPHAGE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANNEXIN A1; CYTOKINES; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; INTERLEUKIN-6; MACROPHAGES; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70249100681     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0804000     Document Type: Article

References (40)

1. Clark, A. R. 2003. MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids? J. Endocrinol. 178: 5-12.
2. Gerke, V., and S. E. Moss. 2002. Annexins: from structure to function. Physiol. Rev. 82: 331-371.
3. Goulding, N. J., H. S. Euzger, S. K. Butt, and M. Perretti. 1998. Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation. Inflamm. Res. 47(Suppl. 3): S158-S165.
4. Perretti, M., and R. J. Flower. 1993. Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1. J. Immunol. 150: 992-999. (Pubitemid 23133679)
5. Perretti, M. 1998. Lipocortin 1 and chemokine modulation of granulocyte and monocyte accumulation in experimental inflammation. Gen. Pharmacol. 31: 545-552. (Pubitemid 28458922)
6. Parente, L., and E. Solito. 2004. Annexin 1: more than an anti-phospholipase protein. Inflamm. Res. 53: 125-132.
7. Damazo, A. S., S. Yona, F. D'Acquisto, R. J. Flower, S. M. Oliani, and M. Perretti. 2005. Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation. Am. J. Pathol. 166: 1607-1617.
8. -/- mouse. FASEB J. 17: 253-255.
9. Yang, Y., M. Leech, P. Hutchinson, S. R. Holdsworth, and E. F. Morand. 1997. Anti-inflammatory effect of lipocortin 1 in experimental arthritis. Inflammation 21: 583-596.
10. Yang, Y., P. Hutchinson, and E. F. Morand. 1999. Inhibitory effect of annexin I on synovial inflammation in rat adjuvant arthritis. Arthritis Rheum. 42: 1538-1544.
11. Yang, Y. H., E. F. Morand, S. J. Getting, M. Paul-Clark, D. L. Liu, S. Yona, R. Hannon, J. C. Buckingham, M. Perretti, and R. J. Flower. 2004. Modulation of inflammation and response to dexamethasone by annexin 1 in antigen-induced arthritis. Arthritis Rheum. 50: 976-984.
12. Damazo, A. S., S. Yona, R. J. Flower, M. Perretti, and S. M. Oliani. 2006. Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis. J. Immunol. 176: 4410-4418.
13. Guha, M., and N. Mackman. 2001. LPS induction of gene expression in human monocytes. Cell. Signal. 13: 85-94.
14. Clark, A. R., and M. Lasa. 2003. Cross-talk between glucocorticoids and mitogen-activated protein kinase signalling pathways. Curr. Opin. Pharmacol. 3: 404-411.
15. Goulding, N. J. 2004. The molecular complexity of glucocorticoid actions in inflammation-a four-ring circus. Curr. Opin. Pharmacol. 4: 629-636.
16. Salojin, K. V., I. B. Owusu, K. A. Millerchip, M. Potter, K. A. Platt, and T. Oravecz. 2006. Essential role of MAPK phosphatase-1 in the negative control of innate immune responses. J. Immunol. 176: 1899-1907.
17. Chi, H., S. P. Barry, R. J. Roth, J. J. Wu, E. A. Jones, A. M. Bennett, and R. A. Flavell. 2006. Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses. Proc. Natl. Acad. Sci. USA 103: 2274-2279.
18. Zhao, Q., X. Wang, L. D. Nelin, Y. Yao, R. Matta, M. E. Manson, R. S. Baliga, X. Meng, C. V. Smith, J. A. Bauer, et al. 2006. MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock. J. Exp. Med. 203: 131-140.
19. Hammer, M., J. Mages, H. Dietrich, A. Servatius, N. Howells, A. C. Cato, and R. Lang. 2006. Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock. J. Exp. Med. 203: 15-20.
20. Alldridge, L. C., H. J. Harris, R. Plevin, R. Hannon, and C. E. Bryant. 1999. The annexin protein lipocortin 1 regulates the MAPK/ERK pathway. J. Biol. Chem. 274: 37620-37628.
21. Yang, Y. H., M. L. Toh, C. D. Clyne, M. Leech, D. Aeberli, J. Xue, A. Dacumos, L. Sharma, and E. F. Morand. 2006. Annexin 1 negatively regulates IL-6 expression via effects on p38 MAPK and MAPK phosphatase-1. Immunology 177: 8148-8153.
22. Berrebi, D., S. Bruscoli, N. Cohen, A. Foussat, G. Migliorati, L. Bouchet-Delbos, M. C. Maillot, A. Portier, J. Couderc, P. Galanaud, et al. 2003. Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an antiinflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10. Blood 101: 729-738.
23. Mittelstadt, P. R., and J. D. Ashwell. 2001. Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ. J. Biol. Chem. 276: 29603-29610.
24. Yang, Y. H., P. Hutchinson, L. L. Santos, and E. F. Morand. 1998. Glucocorticoid inhibition of adjuvant arthritis synovial macrophage nitric oxide production: role of lipocortin 1. Clin. Exp. Immunol. 111: 117-122.
25. Aeberli, D., Y. Yang, A. Mansell, L. Santos, M. Leech, and E. F. Morand. 2006. Endogenous macrophage migration inhibitory factor modulates glucocorticoid sensitivity in macrophages via effects on MAP kinase phosphatase-1 and p38 MAP kinase. FEBS Lett. 580: 974-981.
26. Toh, M. L., Y. Yang, M. Leech, L. Santos, and E. F. Morand. 2004. Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids. Arthritis Rheum. 50: 3118-3128.
27. Yang, Y. H., P. Hall, G. Milenkovski, L. Sharma, P. Hutchinson, E. Melis, P. Carmeliet, P. Tipping, and E. Morand. 2004. Reduction in arthritis severity and modulation of immune function in tissue factor cytoplasmic domain mutant mice. Am. J. Pathol. 164: 109-117.
28. Cannarile, L., F. Fallarino, M. Agostini, S. Cuzzocrea, E. Mazzon, C. Vacca, T. Genovese, G. Migliorati, E. Ayroldi, and C. Riccardi. 2006. Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines. Blood 107: 1039-1047.
29. Toh, M. L., D. Aeberli, D. Lacey, Y. Yang, L. L. Santos, M. Clarkson, L. Sharma, C. Clyne, and E. F. Morand. 2006. Regulation of IL-1 and TNF receptor expression and function by endogenous macrophage migration inhibitory factor. J. Immunol. 177: 4818-4825. (Pubitemid 44469817)
30. Asselin-Labat, M. L., M. David, A. Biola-Vidamment, D. Lecoeuche, M. C. Zennaro, J. Bertoglio, and M. Pallardy. 2004. GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis. Blood 104: 215-223.
31. Asselin-Labat, M. L., A. Biola-Vidamment, S. Kerbrat, M. Lombes, J. Bertoglio, and M. Pallardy. 2005. FoxO3 mediates antagonistic effects of glucocorticoids and interleukin-2 on glucocorticoid-induced leucine zipper expression. Mol. Endocrinol. 19: 1752-1764.
32. Le, Y., P. M. Murphy, and J. M. Wang. 2002. Formyl-peptide receptors revisited. Trends Immunol. 23: 541-548.
33. Gavins, F. N., S. Yona, A. M. Kamal, R. J. Flower, and M. Perretti. 2003. Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related antiinflammatory mechanisms. Blood 101: 4140-4147.
34. Walther, A., K. Riehemann, and V. Gerke. 2000. A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR. Mol. Cell 5: 831-840.
35. Perretti, M., N. Chiang, M. La, I. M. Fierro, S. Marullo, S. J. Getting, E. Solito, and C. N. Serhan. 2002. Endogenous lipid- and peptide-derived antiinflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor. Nat. Med. 8: 1296-1302.
36. Ernst, S., C. Lange, A. Wilbers, V. Goebeler, V. Gerke, and U. Rescher. 2004. An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family. J. Immunol. 172: 7669-7676. (Pubitemid 38747633)
37. Hayhoe, R. P., A. M. Kamal, E. Solito, R. J. Flower, D. Cooper, and M. Perretti. 2006. Annexin 1 and its bioactive peptide inhibit neutrophil- endothelium interactions under flow: indication of distinct receptor involvement. Blood 107: 2123-2130.
38. Ayroldi, E., O. Zollo, A. Macchiarulo, B. Di Marco, C. Marchetti, and C. Riccardi. 2002. Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1. Mol. Cell. Biol. 22: 7929-7941.
39. Ayroldi, E., O. Zollo, A. Bastianelli, C. Marchetti, M. Agostini, R. Di Virgilio, and C. Riccardi. 2007. GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling. J. Clin. Invest. 117: 1605-1615.
40. Cannarile, L., S. Cuzzocrea, L. Santucci, M. Agostini, E. Mazzon, E. Esposito, C. Muia, M. Coppo, R. Di Paola, and C. Riccardi. 2009. Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis. Gastroenterology 136: 530-541.