Dual regulation of glucocorticoid-induced leucine zipper (GILZ) by the glucocorticoid receptor and the PI3-kinase/AKT pathways in multiple myeloma

Journal of Steroid Biochemistry and Molecular Biology

Volumn 110, Issue 3-5, 2008, Pages 244-254

  Grugan, Katharine D ^a   Ma, Chunguang ^a   Singhal, Seema ^a   Krett, Nancy L ^a   Rosen, Steven T ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

AKT; GILZ; Glucocorticoid; Glucocorticoid receptor; Multiple myeloma; PI3 kinase; Signal transduction

Indexed keywords

2 METHOXYESTRADIOL; 2 MORPHOLINO 8 PHENYLCHROMONE; BECLOMETASONE; BECLOMETASONE DIPROPIONATE; DEXAMETHASONE; ENZASTAURIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; LEUCINE ZIPPER PROTEIN; MIFEPRISTONE; PHOSPHATIDYLINOSITOL 3 KINASE; PREDNISOLONE; PREDNISONE; PROTEIN KINASE B; RAPAMYCIN; RECOMBINANT INTERLEUKIN 10; RECOMBINANT INTERLEUKIN 15; RECOMBINANT INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 7; RECOMBINANT SOMATOMEDIN C; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA; RETINOIC ACID; THALIDOMIDE; TRIAMCINOLONE; TRIAMCINOLONE ACETONIDE; TRICIRIBINE; UNINDEXED DRUG; WORTMANNIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; MYELOMA CELL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; DEXAMETHASONE; DRUG COMBINATIONS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-6; MULTIPLE MYELOMA; ONCOGENE PROTEIN V-AKT; PROTEIN KINASE INHIBITORS; RECEPTORS, GLUCOCORTICOID; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 44949178277     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2007.11.003     Document Type: Article

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