Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyΔ12-14 PGJ2

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 52, 2007, Pages 20979-20984

  Rajakariar, Ravindra ^a   Hilliard, Mark ^b   Lawrence, Toby ^a   Trivedi, Seema ^c   Colville Nash, Paul ^d   Bellingan, Geoff ^e   Fitzgerald, Desmond ^b   Yaqoob, Muhammad M ^a   Gilroy, Derek W ^f  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d ST HELIER HOSPITAL   (United Kingdom)

^e UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Antiinflammatory; Cyclooxygnease; Drug development; Eicosanoids; Innate immunity

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; CHEMOKINE; CYTOKINE; PROSTAGLANDIN D2; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN SYNTHASE; 15 DEOXY DELTA(12,14) PROSTAGLANDIN J2; 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J2; ANTIINFLAMMATORY AGENT; DRUG DERIVATIVE; ICOSANOID; ISOMERASE; LIPOCALIN; PROSTAGLANDIN R2 D ISOMERASE; PROSTAGLANDIN R2 D-ISOMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; INFLAMMATION; INNATE IMMUNITY; LEUKOCYTE; LIQUID CHROMATOGRAPHY; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; TANDEM MASS SPECTROMETRY; ACUTE DISEASE; ANIMAL; DRUG DESIGN; ENZYMOLOGY; HEMATOPOIETIC STEM CELL; METABOLISM; MONOCYTE; MOUSE MUTANT;

MAMMALIA; MUS;

ACUTE DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; DRUG DESIGN; EICOSANOIDS; HEMATOPOIETIC STEM CELLS; IMMUNITY, NATURAL; INFLAMMATION; INTRAMOLECULAR OXIDOREDUCTASES; LEUKOCYTES; LIPOCALINS; MICE; MICE, KNOCKOUT; MONOCYTES; NEUTROPHILS; PROSTAGLANDIN D2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 38049181031     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0707394104     Document Type: Article

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