메뉴 건너뛰기




Volumn 28, Issue 5, 2011, Pages 949-958

Diet-induced obesity up-regulates the abundance of GPR43 and GPR120 in a tissue specific manner

Author keywords

GPR120; GPR43; Heart; Liver; mRNA; Obesity; Skeletal muscle; Type 2 diabetes mellitus

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 120; G PROTEIN COUPLED RECEPTOR 43; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 83755225879     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000335820     Document Type: Article
Times cited : (66)

References (79)
  • 1
    • 0034109077 scopus 로고    scopus 로고
    • Obesity, insulin resistance and diabetes - A worldwide epidemic
    • Seidell JC: Obesity, insulin resistance and diabetes-a worldwide epidemic. Br J Nutr 2000;83:S5-8. (Pubitemid 30319075)
    • (2000) British Journal of Nutrition , vol.83 , Issue.SUPPL. 1
    • Seidell, J.C.1
  • 2
    • 0037167664 scopus 로고    scopus 로고
    • World Heart Day 2002: The international burden of cardiovascular disease: Responding to the emerging global epidemic
    • Bonow RO, Smaha LA, Smith SC Jr, Mensah GA, Lenfant C: World Heart Day 2002: the international burden of cardiovascular disease: responding to the emerging global epidemic. Circulation 2002;106:1602-1605.
    • (2002) Circulation , vol.106 , pp. 1602-1605
    • Bonow, R.O.1    Smaha, L.A.2    Smith Jr., S.C.3    Mensah, G.A.4    Lenfant, C.5
  • 3
    • 80051986265 scopus 로고    scopus 로고
    • Globalization of Diabetes: The role of diet, lifestyle, and genes
    • Hu FB: Globalization of Diabetes: The role of diet, lifestyle, and genes. Diabetes Care 2011;34:1249-1257.
    • (2011) Diabetes Care , vol.34 , pp. 1249-1257
    • Hu, F.B.1
  • 4
    • 0030819249 scopus 로고    scopus 로고
    • Body mass index and mortality in a general population sample of men and women the Buffalo Health Study
    • Dorn JM, Schisterman EF, Winkelstein W Jr, Trevisan M: Body mass index and mortality in a general population sample of men and women. The Buffalo Health Study. Am J Epidemiol 1997;146:919-931.
    • (1997) Am J Epidemiol , vol.146 , pp. 919-931
    • Dorn, J.M.1    Schisterman, E.F.2    Winkelstein Jr., W.3    Trevisan, M.4
  • 5
    • 0033001612 scopus 로고    scopus 로고
    • Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality
    • DOI 10.1053/euhj.1998.1235
    • Rosengren A, Wedel H, Wilhelmsen L: Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality. A prospective population study. Eur Heart J 1999;20:269-277. (Pubitemid 29082147)
    • (1999) European Heart Journal , vol.20 , Issue.4 , pp. 269-277
    • Rosengren, A.1    Wedel, H.2    Wilhelmsen, L.3
  • 6
    • 3042798261 scopus 로고    scopus 로고
    • Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: Molecular modeling and mutagenesis approaches to receptor structure and function
    • DOI 10.1016/j.pharmthera.2004.05.002, PII S0163725804000695
    • Kristiansen K: Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-proteincoupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function. Pharmacol Ther 2004;103:21-80. (Pubitemid 38891912)
    • (2004) Pharmacology and Therapeutics , vol.103 , Issue.1 , pp. 21-80
    • Kristiansen, K.1
  • 7
    • 69549111756 scopus 로고    scopus 로고
    • Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients
    • Wellendorph P, Johansen LD, Brauner-Osborne H: Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients. Mol Pharmacol 2009;76:453-465.
    • (2009) Mol Pharmacol , vol.76 , pp. 453-465
    • Wellendorph, P.1    Johansen, L.D.2    Brauner-Osborne, H.3
  • 8
    • 0033118334 scopus 로고    scopus 로고
    • Molecular tinkering of G protein-coupled receptors: An evolutionary success
    • Bockaert J, Pin JP: Molecular tinkering of G protein-coupled receptors: an evolutionary success. EMBO J 1999;18:1723-1729. (Pubitemid 29158516)
    • (1999) EMBO Journal , vol.18 , Issue.7 , pp. 1723-1729
    • Bockaert, J.1    Pin, J.P.2
  • 9
    • 42149181885 scopus 로고    scopus 로고
    • Structural diversity of G protein-coupled receptors and significance for drug discovery
    • Lagerstrom MC, Schioth HB: Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat Rev Drug Discov 2008;7:339-357.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 339-357
    • Lagerstrom, M.C.1    Schioth, H.B.2
  • 10
    • 33749521608 scopus 로고    scopus 로고
    • Latest development in drug discovery on G protein-coupled receptors
    • DOI 10.2174/138920306778559403
    • Lundstrom K: Latest development in drug discovery on G protein-coupled receptors. Curr Protein Pept Sci 2006;7:465-470. (Pubitemid 44524494)
    • (2006) Current Protein and Peptide Science , vol.7 , Issue.5 , pp. 465-470
    • Lundstrom, K.1
  • 12
    • 0242710648 scopus 로고    scopus 로고
    • Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives
    • DOI 10.1016/S0014-5793(03)01196-7
    • Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB: Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives. FEBS Lett 2003;554:381-388. (Pubitemid 37412518)
    • (2003) FEBS Letters , vol.554 , Issue.3 , pp. 381-388
    • Fredriksson, R.1    Hoglund, P.J.2    Gloriam, D.E.I.3    Lagerstrom, M.C.4    Schioth, H.B.5
  • 15
    • 77953287113 scopus 로고    scopus 로고
    • Agonism with the omega-3 fatty acids alpha-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor
    • Burns RN, Moniri NH: Agonism with the omega-3 fatty acids alpha-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor. Biochem Biophys Res Commun 2010;396:1030-1035.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 1030-1035
    • Burns, R.N.1    Moniri, N.H.2
  • 19
    • 0035976638 scopus 로고    scopus 로고
    • Nuclear receptors and lipid physiology: Opening the x-files
    • DOI 10.1126/science.294.5548.1866
    • Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ: Nuclear receptors and lipid physiology: opening the X-files. Science 2001;294:1866-1870. (Pubitemid 33101573)
    • (2001) Science , vol.294 , Issue.5548 , pp. 1866-1870
    • Chawta, A.1    Repa, J.J.2    Evans, R.M.3    Mangelsdorf, D.J.4
  • 20
    • 0036709899 scopus 로고    scopus 로고
    • Is there a single mechanism for fatty acid regulation of gene transcription?
    • DOI 10.1016/S0006-2952(02)01157-7, PII S0006295202011577
    • Duplus E, Forest C: Is there a single mechanism for fatty acid regulation of gene transcription Biochem Pharmacol 2002;64:893-901. (Pubitemid 35232263)
    • (2002) Biochemical Pharmacology , vol.64 , Issue.5-6 , pp. 893-901
    • Duplus, E.1    Forest, C.2
  • 22
    • 0037453280 scopus 로고    scopus 로고
    • 2 R, expressed on leukocytes and activated by short-chain fatty acids
    • DOI 10.1016/S0006-291X(03)00488-1
    • Nilsson NE, Kotarsky K, Owman C, Olde B: Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. Biochem Biophys Res Commun 2003;303:1047-1052. (Pubitemid 36390250)
    • (2003) Biochemical and Biophysical Research Communications , vol.303 , Issue.4 , pp. 1047-1052
    • Nilsson, N.E.1    Kotarsky, K.2    Owman, C.3    Olde, B.4
  • 24
    • 33646376658 scopus 로고    scopus 로고
    • Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine
    • DOI 10.1007/s00441-005-0140-x
    • Karaki S, Mitsui R, Hayashi H, Kato I, Sugiya H, Iwanaga T, Furness JB, Kuwahara A: Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res 2006;324:353-360. (Pubitemid 43673476)
    • (2006) Cell and Tissue Research , vol.324 , Issue.3 , pp. 353-360
    • Karaki, S.-I.1    Mitsui, R.2    Hayashi, H.3    Kato, I.4    Sugiya, H.5    Iwanaga, T.6    Furness, J.B.7    Kuwahara, A.8
  • 27
    • 50449087891 scopus 로고    scopus 로고
    • Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids
    • Ge H, Li X, Weiszmann J, Wang P, Baribault H, Chen JL, Tian H, Li Y: Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology 2008;149:4519-4526.
    • (2008) Endocrinology , vol.149 , pp. 4519-4526
    • Ge, H.1    Li, X.2    Weiszmann, J.3    Wang, P.4    Baribault, H.5    Chen, J.L.6    Tian, H.7    Li, Y.8
  • 28
    • 79954435406 scopus 로고    scopus 로고
    • Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide
    • Kaji I, Karaki S, Tanaka R, Kuwahara A: Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide. J Mol Histol 2011;42:27-38.
    • (2011) J Mol Histol , vol.42 , pp. 27-38
    • Kaji, I.1    Karaki, S.2    Tanaka, R.3    Kuwahara, A.4
  • 30
    • 45849153782 scopus 로고    scopus 로고
    • Cloning and characterization of the rat free fatty acid receptor GPR120: In vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells
    • Tanaka T, Yano T, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G: Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells. Naunyn Schmiedebergs Arch Pharmacol 2008;377:515-522.
    • (2008) Naunyn Schmiedebergs Arch Pharmacol , vol.377 , pp. 515-522
    • Tanaka, T.1    Yano, T.2    Adachi, T.3    Koshimizu, T.A.4    Hirasawa, A.5    Tsujimoto, G.6
  • 32
    • 82355170609 scopus 로고    scopus 로고
    • Adipokines in inflammation, insulin resistance and cardiovascular disease
    • press Skeletal muscle metabolism is a major determinant of resting energy expenditure J Clin Invest 1990;86:1423-1427.
    • Li ZY, Wang P, Miao CY: Adipokines in inflammation, insulin resistance and cardiovascular disease. Clin Exp Pharmacol Physiol 2011;in press.
    • (2011) Clin Exp Pharmacol Physiol
    • Li, Z.Y.1    Wang, P.2    Miao, C.Y.3
  • 33
    • 0025047553 scopus 로고
    • Skeletal muscle metabolism is a major determinant of resting energy expenditure
    • Zurlo F, Larson K, Bogardus C, Ravussin E: Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest 1990;86:1423-1427. (Pubitemid 20372586)
    • (1990) Journal of Clinical Investigation , vol.86 , Issue.5 , pp. 1423-1427
    • Zurlo, F.1    Larson, K.2    Bogardus, C.3    Ravussin, E.4
  • 34
    • 0024237258 scopus 로고
    • Rates and tissue sites of noninsulin-and insulin-mediated glucose uptake in humans
    • Baron AD, Brechtel G, Wallace P, Edelman SV: Rates and tissue sites of noninsulin-and insulin-mediated glucose uptake in humans. Am J Physiol 1988;255:E769-774.
    • (1988) Am J Physiol , vol.255
    • Baron, A.D.1    Brechtel, G.2    Wallace, P.3    Edelman, S.V.4
  • 37
    • 0030020697 scopus 로고    scopus 로고
    • Role of insulin in hepatic fatty acid partitioning: Emerging concepts
    • Zammit VA: Role of insulin in hepatic fatty acid partitioning: emerging concepts. Biochem J 1996;314:1-14. (Pubitemid 26063826)
    • (1996) Biochemical Journal , vol.314 , Issue.1 , pp. 1-14
    • Zammit, V.A.1
  • 38
    • 33745794668 scopus 로고    scopus 로고
    • Signalling mechanisms linking hepatic glucose and lipid metabolism
    • DOI 10.1007/s00125-006-0295-3
    • Weickert MO, Pfeiffer AF: Signalling mechanisms linking hepatic glucose and lipid metabolism. Diabetologia 2006;49:1732-1741. (Pubitemid 44025026)
    • (2006) Diabetologia , vol.49 , Issue.8 , pp. 1732-1741
    • Weickert, M.O.1    Pfeiffer, A.F.H.2
  • 39
    • 0037117651 scopus 로고    scopus 로고
    • Adaptation and maladaptation of the heart in diabetes: Part II: Potential mechanisms
    • DOI 10.1161/01.CIR.0000012467.61045.87
    • Young ME, McNulty P, Taegtmeyer H: Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms. Circulation 2002;105:1861-1870. (Pubitemid 34408899)
    • (2002) Circulation , vol.105 , Issue.15 , pp. 1861-1870
    • Young, M.E.1    McNulty, P.2    Taegtmeyer, H.3
  • 40
    • 53849089210 scopus 로고    scopus 로고
    • Selective reduction in body fat mass and plasma leptin induced by angiotensin-converting enzyme inhibition in rats
    • Mathai ML, Naik S, Sinclair AJ, Weisinger HS, Weisinger RS: Selective reduction in body fat mass and plasma leptin induced by angiotensin-converting enzyme inhibition in rats. Int J Obes (Lond) 2008;32:1576-1584.
    • (2008) Int J Obes (Lond) , vol.32 , pp. 1576-1584
    • Mathai, M.L.1    Naik, S.2    Sinclair, A.J.3    Weisinger, H.S.4    Weisinger, R.S.5
  • 42
    • 0035710746 scopus 로고    scopus 로고
    • -C T method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD: Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 44
    • 33845345276 scopus 로고    scopus 로고
    • Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line
    • DOI 10.1016/j.cellsig.2006.06.004, PII S0898656806001495
    • Yonezawa T, Kobayashi Y, Obara Y: Short-chain fatty acids induce acute phosphorylation of the p38 mitogenactivated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line. Cell Signal 2007;19:185-193. (Pubitemid 44880254)
    • (2007) Cellular Signalling , vol.19 , Issue.1 , pp. 185-193
    • Yonezawa, T.1    Kobayashi, Y.2    Obara, Y.3
  • 45
    • 79953221811 scopus 로고    scopus 로고
    • Counter modulation of fatty acid-induced proinflammatory NFB signalling in rat skeletal muscle cells by AMPK
    • Green CJ, Macrae K, Fogarty S, Hardie DG, Sakamoto K, Hundal HS: Counter modulation of fatty acid-induced proinflammatory NFB signalling in rat skeletal muscle cells by AMPK. Biochem J 2011;435:463-474.
    • (2011) Biochem J , vol.435 , pp. 463-474
    • Green, C.J.1    MacRae, K.2    Fogarty, S.3    Hardie, D.G.4    Sakamoto, K.5    Hundal, H.S.6
  • 46
    • 33750877988 scopus 로고    scopus 로고
    • Palmitate-mediated downregulation of peroxisome proliferator-activated receptor- coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation
    • DOI 10.2337/db05-1494
    • Coll T, Jove M, Rodriguez-Calvo R, Eyre E, Palomer X, Sanchez RM, Merlos M, Laguna JC, Vazquez-Carrera M: Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation. Diabetes 2006;55:2779-2787. (Pubitemid 44923677)
    • (2006) Diabetes , vol.55 , Issue.10 , pp. 2779-2787
    • Coll, T.1    Jove, M.2    Rodriguez-Calvo, R.3    Eyre, E.4    Palomer, X.5    Sanchez, R.M.6    Merlos, M.7    Laguna, J.C.8    Vazquez-Carrera, M.9
  • 47
    • 21344444333 scopus 로고    scopus 로고
    • A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
    • DOI 10.2337/diabetes.54.7.1926
    • Sparks LM, Xie H, Koza RA, Mynatt R, Hulver MW, Bray GA, Smith SR: A highfat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes 2005;54:1926-1933. (Pubitemid 40911253)
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 1926-1933
    • Sparks, L.M.1    Xie, H.2    Koza, R.A.3    Mynatt, R.4    Hulver, M.W.5    Bray, G.A.6    Smith, S.R.7
  • 48
    • 28544438180 scopus 로고    scopus 로고
    • PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: A mechanism for transcriptional control of muscle glucose metabolism
    • DOI 10.1128/MCB.25.24.10684-10694.2005
    • Wende AR, Huss JM, Schaeffer PJ, Giguere V, Kelly DP: PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: A mechanism for transcriptional control of muscle glucose metabolism. Mol Cell Biol 2005;25:10684-10694. (Pubitemid 41747115)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.24 , pp. 10684-10694
    • Wende, A.R.1    Huss, J.M.2    Schaeffer, P.J.3    Giguere, V.4    Kelly, D.P.5
  • 50
    • 0038036024 scopus 로고    scopus 로고
    • Bioenergetic analysis of peroxisome proliferator-activated receptor coactivators 1alpha and 1 (PGC-1alpha and PGC-1) in muscle cells
    • DOI 10.1074/jbc.M301850200
    • St-Pierre J, Lin J, Krauss S, Tarr PT, Yang R, Newgard CB, Spiegelman BM: Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J Biol Chem 2003;278:26597-26603. (Pubitemid 36876804)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.29 , pp. 26597-26603
    • St-Pierre, J.1    Lin, J.2    Krauss, S.3    Tarr, P.T.4    Yang, R.5    Newgard, C.B.6    Spiegelman, B.M.7
  • 51
    • 25844432311 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor- co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency
    • DOI 10.1074/jbc.M507621200
    • Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, Muoio DM: Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipidinduced mitochondrial inefficiency. J Biol Chem 2005;280:33588-33598. (Pubitemid 41397160)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.39 , pp. 33588-33598
    • Koves, T.R.1    Li, P.2    An, J.3    Akimoto, T.4    Slentz, D.5    Ilkayeva, O.6    Dohm, G.L.7    Yan, Z.8    Newgard, C.B.9    Muoio, D.M.10
  • 53
    • 0033977890 scopus 로고    scopus 로고
    • The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
    • DOI 10.1128/MCB.20.5.1868-1876.2000
    • Vega RB, Huss JM, Kelly DP: The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol Cell Biol 2000;20:1868-1876. (Pubitemid 30100203)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.5 , pp. 1868-1876
    • Vega, R.B.1    Huss, J.M.2    Kelly, D.P.3
  • 55
    • 12344287423 scopus 로고    scopus 로고
    • Inhibition of ryanodine receptor 1 in fast skeletal muscle fibers induces a fast-to-slow muscle fiber type transition
    • DOI 10.1242/jcs.01543
    • Jordan T, Jiang H, Li H, DiMario JX: Inhibition of ryanodine receptor 1 in fast skeletal muscle fibers induces a fast-toslow muscle fiber type transition. J Cell Sci 2004;117:6175-6183. (Pubitemid 40123981)
    • (2004) Journal of Cell Science , vol.117 , Issue.25 , pp. 6175-6183
    • Jordan, T.1    Jiang, H.2    Li, H.3    DiMario, J.X.4
  • 57
    • 4744344777 scopus 로고    scopus 로고
    • Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappaB
    • DOI 10.1074/jbc.M406514200
    • Sinha S, Perdomo G, Brown NF, O'Doherty RM: Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B. J Biol Chem 2004;279:41294-41301. (Pubitemid 39313568)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.40 , pp. 41294-41301
    • Sinha, S.1    Perdomo, G.2    Brown, N.F.3    O'Doherty, R.M.4
  • 59
    • 0035504158 scopus 로고    scopus 로고
    • GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: Potential activation of GLUT4 via p38 mitogen-activated protein kinase
    • DOI 10.1042/0264-6021:3590639
    • Somwar R, Kim DY, Sweeney G, Huang C, Niu W, Lador C, Ramlal T, Klip A: GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase. Biochem J 2001;359:639-649. (Pubitemid 33063389)
    • (2001) Biochemical Journal , vol.359 , Issue.3 , pp. 639-649
    • Somwar, R.1    Kim, D.Y.2    Sweeney, G.3    Huang, C.4    Niu, W.5    Lador, C.6    Ramlal, T.7    Klip, A.8
  • 60
    • 0033537853 scopus 로고    scopus 로고
    • An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes
    • Sweeney G, Somwar R, Ramlal T, Volchuk A, Ueyama A, Klip A: An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes. J Biol Chem 1999;274:10071-10078.
    • (1999) J Biol Chem , vol.274 , pp. 10071-10078
    • Sweeney, G.1    Somwar, R.2    Ramlal, T.3    Volchuk, A.4    Ueyama, A.5    Klip, A.6
  • 62
    • 77249131862 scopus 로고    scopus 로고
    • Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin
    • Mauvoisin D, Prevost M, Ducheix S, Arnaud MP, Mounier C: Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin. Mol Cell Endocrinol 2010;319:116-128.
    • (2010) Mol Cell Endocrinol , vol.319 , pp. 116-128
    • Mauvoisin, D.1    Prevost, M.2    Ducheix, S.3    Arnaud, M.P.4    Mounier, C.5
  • 63
    • 78650510481 scopus 로고    scopus 로고
    • Hormonal and nutritional regulation of SCD1 gene expression
    • Mauvoisin D, Mounier C: Hormonal and nutritional regulation of SCD1 gene expression. Biochimie 2011;93:78-86.
    • (2011) Biochimie , vol.93 , pp. 78-86
    • Mauvoisin, D.1    Mounier, C.2
  • 65
    • 0034721772 scopus 로고    scopus 로고
    • MAP kinases Erk1/2 phosphorylate sterol regulatory elementbinding protein (SREBP)-1a at serine 117 in vitro
    • Roth G, Kotzka J, Kremer L, Lehr S, Lohaus C, Meyer HE, Krone W, Muller-Wieland D: MAP kinases Erk1/2 phosphorylate sterol regulatory elementbinding protein (SREBP)-1a at serine 117 in vitro. J Biol Chem 2000;275:33302-33307.
    • (2000) J Biol Chem , vol.275 , pp. 33302-33307
    • Roth, G.1    Kotzka, J.2    Kremer, L.3    Lehr, S.4    Lohaus, C.5    Meyer, H.E.6    Krone, W.7    Muller-Wieland, D.8
  • 67
    • 0034804783 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Transcriptional regulators of lipid synthetic genes
    • DOI 10.1016/S0163-7827(01)00010-8, PII S0163782701000108
    • Shimano H: Sterol regulatory elementbinding proteins (SREBPs): transcriptional regulators of lipid synthetic genes. Prog Lipid Res 2001;40:439-452. (Pubitemid 32929966)
    • (2001) Progress in Lipid Research , vol.40 , Issue.6 , pp. 439-452
    • Shimano, H.1
  • 68
    • 11144247719 scopus 로고    scopus 로고
    • Loss of myostatin expression alters fiber-type distribution and expression of myosin heavy chain isoforms in slow- and fast-type skeletal muscle
    • DOI 10.1002/mus.20175
    • Girgenrath S, Song K, Whittemore LA: Loss of myostatin expression alters fibertype distribution and expression of myosin heavy chain isoforms in slowand fast-type skeletal muscle. Muscle Nerve 2005;31:34-40. (Pubitemid 40053924)
    • (2005) Muscle and Nerve , vol.31 , Issue.1 , pp. 34-40
    • Girgenrath, S.1    Song, K.2    Whittemore, L.-A.3
  • 70
    • 0029264938 scopus 로고
    • Fuel selection, muscle fibre
    • Hultman E: Fuel selection, muscle fibre. Proc Nutr Soc 1995;54:107-121.
    • (1995) Proc Nutr Soc , vol.54 , pp. 107-121
    • Hultman, E.1
  • 71
    • 21244503501 scopus 로고    scopus 로고
    • Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1
    • DOI 10.1074/jbc.M412385200
    • Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A, Tsujimoto G: Free fatty acids inhibit serum deprivationinduced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1. J Biol Chem 2005;280:19507-19515. (Pubitemid 41379471)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.20 , pp. 19507-19515
    • Katsuma, S.1    Hatae, N.2    Yano, T.3    Ruike, Y.4    Kimura, M.5    Hirasawa, A.6    Tsujimoto, G.7
  • 72
    • 33646162635 scopus 로고    scopus 로고
    • GRKs and betaarrestins: Roles in receptor silencing, trafficking and signaling
    • Reiter E, Lefkowitz RJ: GRKs and betaarrestins: roles in receptor silencing, trafficking and signaling. Trends Endocrinol Metab 2006;17:159-165.
    • (2006) Trends Endocrinol Metab , vol.17 , pp. 159-165
    • Reiter, E.1    Lefkowitz, R.J.2
  • 75
    • 77649162900 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in cardiac hypertrophy
    • Kehat I, Molkentin JD: Extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in cardiac hypertrophy. Ann N Y Acad Sci 2010;1188:96-102.
    • (2010) Ann N y Acad Sci , vol.1188 , pp. 96-102
    • Kehat, I.1    Molkentin, J.D.2
  • 76
    • 0026497732 scopus 로고
    • Left ventricular mass and body size in normotensive children and adults: Assessment of allometric relations and impact of overweight
    • de Simone G, Daniels SR, Devereux RB, Meyer RA, Roman MJ, de Divitiis O, Alderman MH: Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight. J Am Coll Cardiol 1992;20:1251-1260.
    • (1992) J Am Coll Cardiol , vol.20 , pp. 1251-1260
    • De Simone, G.1    Daniels, S.R.2    Devereux, R.B.3    Meyer, R.A.4    Roman, M.J.5    De Divitiis, O.6    Alderman, M.H.7
  • 77
    • 78651256133 scopus 로고    scopus 로고
    • Impact of obesity on hypertensioninduced cardiac remodeling: Role of oxidative stress and its modulation by gemfibrozil treatment in rats
    • Singh R, Singh AP, Singh M, Krishan P: Impact of obesity on hypertensioninduced cardiac remodeling: role of oxidative stress and its modulation by gemfibrozil treatment in rats. Free Radic Biol Med 2011;50:363-370.
    • (2011) Free Radic Biol Med , vol.50 , pp. 363-370
    • Singh, R.1    Singh, A.P.2    Singh, M.3    Krishan, P.4
  • 79
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
    • Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP: Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990;322:1561-1566. (Pubitemid 20176696)
    • (1990) New England Journal of Medicine , vol.322 , Issue.22 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.