-
1
-
-
0030636560
-
Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo
-
Sundstedt, A., et al. 1997. Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo. J. Immunol. 158:180-186.
-
(1997)
J. Immunol.
, vol.158
, pp. 180-186
-
-
Sundstedt, A.1
-
2
-
-
0037310355
-
Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo
-
Sundstedt, A., O'Neill, E.J., Nicolson, K.S., and Wraith, D.C. 2003. Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo. J. Immunol. 170:1240-1248.
-
(2003)
J. Immunol.
, vol.170
, pp. 1240-1248
-
-
Sundstedt, A.1
O'Neill, E.J.2
Nicolson, K.S.3
Wraith, D.C.4
-
3
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux, H., et al. 1997. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature. 389:737-742.
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
-
4
-
-
0035181582
-
Type 1 T regulatory cells
-
Roncarolo, M.G., Bacchetta, R., Bordignon, C., Narula, S., and Levings, M.K. 2001. Type 1 T regulatory cells. Immunol. Rev. 182:68-79.
-
(2001)
Immunol. Rev.
, vol.182
, pp. 68-79
-
-
Roncarolo, M.G.1
Bacchetta, R.2
Bordignon, C.3
Narula, S.4
Levings, M.K.5
-
5
-
-
0031964338
-
Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo
-
Buer, J., et al. 1998. Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo. J. Exp. Med. 187:177-183.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 177-183
-
-
Buer, J.1
-
6
-
-
0037018104
-
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- And Th2-inducing cytokines
-
Barrat, F.J., et al. 2002. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195:603-616.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
-
7
-
-
0036165718
-
Natural CD4CD25(+) regulatory T cells control the burst of superantigen-induced cytokine production: The role of IL-10
-
Pontoux, C., Banz, A., and Papiernik, M. 2002. Natural CD4CD25(+) regulatory T cells control the burst of superantigen-induced cytokine production: the role of IL-10. Int. Immunol. 14:233-239.
-
(2002)
Int. Immunol.
, vol.14
, pp. 233-239
-
-
Pontoux, C.1
Banz, A.2
Papiernik, M.3
-
8
-
-
2442450433
-
IL-10 secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occuring CD4+CD25+ regulatory T cells
-
Vieira, P.L., et al. 2004. IL-10 secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occuring CD4+CD25+ regulatory T cells. J. Immunol. 172:5986-5993.
-
(2004)
J. Immunol.
, vol.172
, pp. 5986-5993
-
-
Vieira, P.L.1
-
9
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., and Toda, M. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155:1151-1164.
-
(1995)
J. Immunol.
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
10
-
-
0035180065
-
Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
-
Sakaguchi, S., et al. 2001. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 182:18-32.
-
(2001)
Immunol. Rev.
, vol.182
, pp. 18-32
-
-
Sakaguchi, S.1
-
11
-
-
0343878233
-
Suppressor T cells: Rebirth, function and homeostasis
-
Shevach, E.M. 2000. Suppressor T cells: Rebirth, function and homeostasis. Curr. Biol. 10:R572-R575.
-
(2000)
Curr. Biol.
, vol.10
-
-
Shevach, E.M.1
-
12
-
-
0036597371
-
CD4+CD25+ suppressor T cells: More questions than answers
-
Shevach, E.M. 2002. CD4+CD25+ suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2:389-400.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 389-400
-
-
Shevach, E.M.1
-
13
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J.D., Gavin, M.A., and Rudensky, A.Y. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4:330-336.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
14
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T., and Sakaguchi, S. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science. 299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
15
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., Cox, T., Yasayko, S.A., and Ramsdell, F. 2003. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4:337-342.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
16
-
-
0041931076
-
Foxp3 and natural regulatory T cells: Key to a cell lineage?
-
Ramsdell, F. 2003. Foxp3 and natural regulatory T cells: key to a cell lineage? Immunity. 19:165-168.
-
(2003)
Immunity
, vol.19
, pp. 165-168
-
-
Ramsdell, F.1
-
17
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman, C., Mauze, S., Leach, M.W., Coffman, R.L., and Powrie, F. 1999. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190:995-1004.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
18
-
-
0242580070
-
CD4+CD25+ regulatory T cells cure murine colitis: The role of IL-10, TGF-beta, and CTLA4
-
Liu, H., Hu, B., Xu, D., and Liew, F.Y. 2003. CD4+CD25+ regulatory T cells cure murine colitis: the role of IL-10, TGF-beta, and CTLA4. J. Immunol. 171:5012-5017.
-
(2003)
J. Immunol.
, vol.171
, pp. 5012-5017
-
-
Liu, H.1
Hu, B.2
Xu, D.3
Liew, F.Y.4
-
19
-
-
12944310982
-
IL-10-producing T cells suppress immune responses in anergic tuberculosis patients
-
Boussiotis, V.A., et al. 2000. IL-10-producing T cells suppress immune responses in anergic tuberculosis patients. J. Clin. Invest. 105:1317-1325.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1317-1325
-
-
Boussiotis, V.A.1
-
20
-
-
10744227590
-
Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens
-
Aandahl, E.M., Michaelsson, J., Moretto, W.J., Hecht, P.M., and Nixon, D.F. 2004. Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J. Virol. 78:2454-2459.
-
(2004)
J. Virol.
, vol.78
, pp. 2454-2459
-
-
Aandahl, E.M.1
Michaelsson, J.2
Moretto, W.J.3
Hecht, P.M.4
Nixon, D.F.5
-
21
-
-
3543098686
-
CD25+CD4+ regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4 and CD8 HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
-
Kinter, A.L., et al. 2004. CD25+CD4+ regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4 and CD8 HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J. Exp. Med. 200:331-343.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 331-343
-
-
Kinter, A.L.1
-
22
-
-
19344374571
-
HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
-
Oswald-Richter, K., et al. 2004. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. PLoS Biol. 2:E198.
-
(2004)
PLoS Biol.
, vol.2
-
-
Oswald-Richter, K.1
-
23
-
-
0037220923
-
CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice
-
Xu, D., et al. 2003. CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. J. Immunol. 170:394-399.
-
(2003)
J. Immunol.
, vol.170
, pp. 394-399
-
-
Xu, D.1
-
24
-
-
0026708718
-
Regulation of immunity to parasites by T cells and T cell-derived cytokines
-
Sher, A., and Coffman, R.L. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu. Rev. Immunol. 10:385-409.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 385-409
-
-
Sher, A.1
Coffman, R.L.2
-
25
-
-
2442668054
-
Development and function of T helper 1 cells
-
O'Garra, A., and Robinson, D. 2004. Development and function of T helper 1 cells. Adv. Immunol. 83:133-162.
-
(2004)
Adv. Immunol.
, vol.83
, pp. 133-162
-
-
O'Garra, A.1
Robinson, D.2
-
26
-
-
0032033419
-
Cytokines induce the development of functionally heterogeneous T helper cell subsets
-
O'Garra, A. 1998. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity. 8:275-283.
-
(1998)
Immunity
, vol.8
, pp. 275-283
-
-
O'Garra, A.1
-
27
-
-
0035062021
-
Interleukin-10 and the interleukin-10 receptor
-
Moore, K.W., de Waal Malefyt, R., Coffman, R.L., and O'Garra, A. 2001. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19:683-765.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 683-765
-
-
Moore, K.W.1
De Waal Malefyt, R.2
Coffman, R.L.3
O'Garra, A.4
-
28
-
-
0036795531
-
B cells regulate autoimmunity by provision of IL-10
-
Fillatreau, S., Sweenie, C.H., McGeachy, M.J., Gray, D., and Anderton, S.M. 2002. B cells regulate autoimmunity by provision of IL-10. Nat. Immunol. 3:944-950.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 944-950
-
-
Fillatreau, S.1
Sweenie, C.H.2
McGeachy, M.J.3
Gray, D.4
Anderton, S.M.5
-
29
-
-
0037148511
-
Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
-
McGuirk, P., McCann, C., and Mills, K.H. 2002 Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J. Exp. Med. 195:221-231.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 221-231
-
-
McGuirk, P.1
McCann, C.2
Mills, K.H.3
-
30
-
-
0036786447
-
Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering
-
Edwards, A.D., et al. 2002. Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering. J. Immunol. 169:3652-3660.
-
(2002)
J. Immunol.
, vol.169
, pp. 3652-3660
-
-
Edwards, A.D.1
-
31
-
-
0019400179
-
The curse of Prometheus is laid upon the immune system
-
Ohno, S., Epplen, J.T., Matsunaga, T., and Hozumi, T. 1981. The curse of Prometheus is laid upon the immune system. Prog. Allergy. 28:8-39.
-
(1981)
Prog. Allergy.
, vol.28
, pp. 8-39
-
-
Ohno, S.1
Epplen, J.T.2
Matsunaga, T.3
Hozumi, T.4
-
32
-
-
0031446317
-
CD4+ T-cell subsets in autoimmunity
-
O'Garra, A., Steinman, L., and Gijbels, K. 1997. CD4+ T-cell subsets in autoimmunity. Curr. Opin. Immunol. 9:872-883.
-
(1997)
Curr. Opin. Immunol.
, vol.9
, pp. 872-883
-
-
O'Garra, A.1
Steinman, L.2
Gijbels, K.3
-
33
-
-
0026077909
-
Induction and maintenance of anergy in mature T cells
-
Jenkins, M.K., et al. 1991. Induction and maintenance of anergy in mature T cells. Adv. Exp. Med. Biol. 292:167-176.
-
(1991)
Adv. Exp. Med. Biol.
, vol.292
, pp. 167-176
-
-
Jenkins, M.K.1
-
34
-
-
0028179230
-
Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
-
Powrie, F., Correa-Oliveira, R., Mauze, S., and Coffman, R.L. 1994. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 179:589-600.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 589-600
-
-
Powrie, F.1
Correa-Oliveira, R.2
Mauze, S.3
Coffman, R.L.4
-
35
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy, K.J., and Powrie, F. 2001. Regulatory T cells in the control of immune pathology. Nat. Immunol. 2:816-822.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 816-822
-
-
Maloy, K.J.1
Powrie, F.2
-
36
-
-
0037783493
-
Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance
-
Cobbold, S.P., Graca, L., Lin, C.Y., Adams, E., and Waldmann, H. 2003. Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance. Transpl. Int. 16:66-75.
-
(2003)
Transpl. Int.
, vol.16
, pp. 66-75
-
-
Cobbold, S.P.1
Graca, L.2
Lin, C.Y.3
Adams, E.4
Waldmann, H.5
-
37
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read, S., Malmstrom, V., and Powrie, F. 2000. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med. 192:295-302.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
38
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxitic T lymphocyte-associated antigen 4
-
Takahashi, T., et al. 2000. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxitic T lymphocyte-associated antigen 4. J. Exp. Med. 192:303-310.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
-
39
-
-
0033579883
-
Regulatory T cells in the control of autoimmunity: The essential role of transforming growth factor b and interleukin 4 in the prevention of autoimmune thryroiditis in rats by peripheral CD4+ CD45RC- Cells and CD4+ CD8-thymocytes
-
Seddon, B., and Mason, D. 1999. Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor b and interleukin 4 in the prevention of autoimmune thryroiditis in rats by peripheral CD4+ CD45RC- cells and CD4+ CD8-thymocytes. J. Exp. Med. 189:279-288.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 279-288
-
-
Seddon, B.1
Mason, D.2
-
40
-
-
0029956024
-
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells
-
Powrie, F., Carlino, J., Leach, M.W., Mauze, S., and Coffman, R.L. 1996. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J. Exp. Med. 183:2669-2674.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2669-2674
-
-
Powrie, F.1
Carlino, J.2
Leach, M.W.3
Mauze, S.4
Coffman, R.L.5
-
41
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
Nakamura, K., Kitani, A., and Strober, W. 2001 Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta J. Exp. Med. 194:629-644.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
42
-
-
0141703239
-
CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes
-
Green, E.A., Gorelik, L., McGregor, C.M., Tran, E.H., and Flavell, R.A. 2003. CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes. Proc. Natl. Acad. Sci. U. S. A. 100:10878-10883.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 10878-10883
-
-
Green, E.A.1
Gorelik, L.2
McGregor, C.M.3
Tran, E.H.4
Flavell, R.A.5
-
43
-
-
0037371301
-
CD4+CD25- T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism
-
Oida, T., et al. 2003. CD4+CD25- T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism. J. Immunol. 170:2516-2522.
-
(2003)
J. Immunol.
, vol.170
, pp. 2516-2522
-
-
Oida, T.1
-
44
-
-
0036732461
-
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
-
Akbari, O., et al. 2002. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat. Med. 8:1024-1032.
-
(2002)
Nat. Med.
, vol.8
, pp. 1024-1032
-
-
Akbari, O.1
-
45
-
-
0030847054
-
Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
-
Weiner, H.L. 1997. Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol. Today. 18:335-343.
-
(1997)
Immunol. Today
, vol.18
, pp. 335-343
-
-
Weiner, H.L.1
-
46
-
-
0029847368
-
Functional diversity of helper T lymphocytes
-
Abbas, A.K., Murphy, K.M., and Sher, A. 1996. Functional diversity of helper T lymphocytes. Nature. 383:787-793.
-
(1996)
Nature
, vol.383
, pp. 787-793
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
47
-
-
0027534510
-
Differential regulation of murine T lymphocyte subsets
-
Fitch, F.W., McKisic, M.D., Lancki, D.W., and Gajewski, T.F. 1993. Differential regulation of murine T lymphocyte subsets. Annu. Rev. Immunol. 11:29-48.
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 29-48
-
-
Fitch, F.W.1
McKisic, M.D.2
Lancki, D.W.3
Gajewski, T.F.4
-
48
-
-
8044250881
-
Regulation of the interleukin (IL)-12β2 subunit expression in developing T helper 1 (Th1) and Th2 cells
-
Szabo, S., Dighe, A.S., Gubler, U., and Murphy, K.M. 1997. Regulation of the interleukin (IL)-12β2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 185:817-824.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 817-824
-
-
Szabo, S.1
Dighe, A.S.2
Gubler, U.3
Murphy, K.M.4
-
49
-
-
0030892136
-
Selective expression of an interleukin-12 receptor component by human T helper 1 cells
-
Rogge, L., et al. 1997. Selective expression of an interleukin-12 receptor component by human T helper 1 cells. J. Exp. Med. 185:825-831.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 825-831
-
-
Rogge, L.1
-
50
-
-
0034129629
-
Signaling and transcription in T helper development
-
Murphy, K.M., et al. 2000. Signaling and transcription in T helper development. Annu. Rev. Immunol. 18:451-494.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 451-494
-
-
Murphy, K.M.1
-
51
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo, S.J., et al. 2000. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 100:655-669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
-
52
-
-
0025818157
-
Helper T-cell subsets in mouse leishmaniasis:induction, expansion and effector function
-
Locksley, R.M., and Scott, P. 1991. Helper T-cell subsets in mouse leishmaniasis:induction, expansion and effector function. Immunol. Today. 12:58-61.
-
(1991)
Immunol. Today
, vol.12
, pp. 58-61
-
-
Locksley, R.M.1
Scott, P.2
-
53
-
-
0028179006
-
Lymphocyte responses and cytokines
-
Paul, W.E., and Seder, R.A. 1994. Lymphocyte responses and cytokines. Cell. 76:241-251.
-
(1994)
Cell
, vol.76
, pp. 241-251
-
-
Paul, W.E.1
Seder, R.A.2
-
54
-
-
0027156737
-
Cytokine regulation of T-cell function: Potential for therapeutic intervention
-
Powrie, F., and Coffman, R.L. 1993. Cytokine regulation of T-cell function: potential for therapeutic intervention. Immunol. Today. 14:270-274.
-
(1993)
Immunol. Today
, vol.14
, pp. 270-274
-
-
Powrie, F.1
Coffman, R.L.2
-
55
-
-
0030739650
-
Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from disease
-
Lafaille, J.J., et al. 1997. Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from disease. J. Exp. Med. 186:307-312.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 307-312
-
-
Lafaille, J.J.1
-
56
-
-
0030742237
-
T helper 2 (Th2) cells induce acute pancreatitis amd diabetes in immune-compromised non-obese diabetic (NOD) mice
-
Pakala, S.V., Kurrer, M.O., and Katz, J.D. 1997. T helper 2 (Th2) cells induce acute pancreatitis amd diabetes in immune-compromised non-obese diabetic (NOD) mice. J. Exp. Med. 186:299-306.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 299-306
-
-
Pakala, S.V.1
Kurrer, M.O.2
Katz, J.D.3
-
57
-
-
10744220561
-
Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence
-
Terabe, M., et al. 2003. Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. J. Exp. Med. 198:1741-1752.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1741-1752
-
-
Terabe, M.1
-
58
-
-
0742321750
-
Role of IL-13 in regulation of anti-tumor immunity and tumor growth
-
Terabe, M., Park, J.M., and Berzofsky, J.A. 2004. Role of IL-13 in regulation of anti-tumor immunity and tumor growth. Cancer Immunol. Immunother. 53:79-85.
-
(2004)
Cancer Immunol. Immunother.
, vol.53
, pp. 79-85
-
-
Terabe, M.1
Park, J.M.2
Berzofsky, J.A.3
-
59
-
-
1642344677
-
Interleukin-10, T regulatory cells and specific allergy treatment
-
Blaser, K., and Akdis, C.A. 2004. Interleukin-10, T regulatory cells and specific allergy treatment. Clin. Exp. Allergy. 34:328-331.
-
(2004)
Clin. Exp. Allergy
, vol.34
, pp. 328-331
-
-
Blaser, K.1
Akdis, C.A.2
-
60
-
-
0034846513
-
Role of IL-10 in allergen-specific immunotherapy and normal response to allergens
-
Akdis, C.A., and Blaser, K. 2001. Role of IL-10 in allergen-specific immunotherapy and normal response to allergens. Microbes Infect. 3:891-898.
-
(2001)
Microbes Infect.
, vol.3
, pp. 891-898
-
-
Akdis, C.A.1
Blaser, K.2
-
61
-
-
4043052238
-
Regulatory T cells and mechanisms of immune system control
-
O'Garra, A., and Vieira, P. 2004. Regulatory T cells and mechanisms of immune system control. Nat. Med. 10:801-805.
-
(2004)
Nat. Med.
, vol.10
, pp. 801-805
-
-
O'Garra, A.1
Vieira, P.2
-
62
-
-
0037383757
-
Twenty-first century Foxp3
-
O'Garra, A., and Vieira, P. 2003. Twenty-first century Foxp3. Nat. Immunol. 4:304-306.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 304-306
-
-
O'Garra, A.1
Vieira, P.2
-
63
-
-
0035914926
-
Regulatory role of T cells producing both interferon gamma and interleukin 10 in persistent infection
-
Trinchieri, G. 2001. Regulatory role of T cells producing both interferon gamma and interleukin 10 in persistent infection. J. Exp. Med. 194:F53-F57.
-
(2001)
J. Exp. Med.
, vol.194
-
-
Trinchieri, G.1
-
64
-
-
0032797911
-
A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice
-
Li, C., Corraliza, I., and Langhorne, J. 1999. A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice. Infect. Immun. 67:4435-4442.
-
(1999)
Infect. Immun.
, vol.67
, pp. 4435-4442
-
-
Li, C.1
Corraliza, I.2
Langhorne, J.3
-
65
-
-
0027521572
-
Interleukin-10 deficient mice develop chronic enterocolitis
-
Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K., and Muller, W. 1993. Interleukin-10 deficient mice develop chronic enterocolitis. Cell. 75:263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
66
-
-
0032076698
-
Modifications of CD8+ T cell function during in vivo memory or tolerance induction
-
Tanchot, C., et al. 1998. Modifications of CD8+ T cell function during in vivo memory or tolerance induction. Immunity. 8:581-590.
-
(1998)
Immunity
, vol.8
, pp. 581-590
-
-
Tanchot, C.1
-
67
-
-
0037128654
-
Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells
-
Gilliet, M., and Liu, Y.J. 2002. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J. Exp. Med. 195:695-704.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 695-704
-
-
Gilliet, M.1
Liu, Y.J.2
-
68
-
-
0026012259
-
Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones
-
Salgame, P., et al. 1991. Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science. 254:279-282.
-
(1991)
Science
, vol.254
, pp. 279-282
-
-
Salgame, P.1
-
69
-
-
0026529405
-
IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages
-
Gazzinelli, R.T., Oswald, I.P., James, S.L., and Sher, A. 1992. IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages. J. Immunol. 148:1792-1796.
-
(1992)
J. Immunol.
, vol.148
, pp. 1792-1796
-
-
Gazzinelli, R.T.1
Oswald, I.P.2
James, S.L.3
Sher, A.4
-
70
-
-
0031112271
-
IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi
-
Hunter, C.A., et al. 1997. IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi. J. Immunol. 158:3311-3316.
-
(1997)
J. Immunol.
, vol.158
, pp. 3311-3316
-
-
Hunter, C.A.1
-
71
-
-
0032425062
-
Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- And gamma interferon-dependent mechanism
-
Kullberg, M.C., et al. 1998. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism. Infect. Immun. 66:5157-5166.
-
(1998)
Infect. Immun.
, vol.66
, pp. 5157-5166
-
-
Kullberg, M.C.1
-
72
-
-
0037243827
-
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
-
Maloy, K.J., et al. 2003. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197:111-119.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 111-119
-
-
Maloy, K.J.1
-
73
-
-
0028325080
-
Clinical and immunopathological aspects of disseminated cutaneous leishmaniasis
-
Carvalho, E.M., Barral, A., Costa, J.M., Bittencourt, A., and Marsden, P. 1994. Clinical and immunopathological aspects of disseminated cutaneous leishmaniasis. Acta Trop. 56:315-325.
-
(1994)
Acta Trop.
, vol.56
, pp. 315-325
-
-
Carvalho, E.M.1
Barral, A.2
Costa, J.M.3
Bittencourt, A.4
Marsden, P.5
-
74
-
-
0030900568
-
Regulation of parasite antigen-driven immune responses by interleukin-10 (IL-10) and IL-12 in lymphatic filariasis
-
Mahanty, S., et al. 1997. Regulation of parasite antigen-driven immune responses by interleukin-10 (IL-10) and IL-12 in lymphatic filariasis. Infect. Immun. 65:1742-1747.
-
(1997)
Infect. Immun.
, vol.65
, pp. 1742-1747
-
-
Mahanty, S.1
-
75
-
-
15844364756
-
Cytokine control of parasite-specific anergy in human urinary schistosomiasis. IL-10 modulates lymphocyte reactivity
-
King, C.L., et al. 1996. Cytokine control of parasite-specific anergy in human urinary schistosomiasis. IL-10 modulates lymphocyte reactivity. J. Immunol. 156:4715-4721.
-
(1996)
J. Immunol.
, vol.156
, pp. 4715-4721
-
-
King, C.L.1
-
76
-
-
0027232912
-
Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy
-
Sieling, P.A., et al. 1993. Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy. J. Immunol. 150:5501-5510.
-
(1993)
J. Immunol.
, vol.150
, pp. 5501-5510
-
-
Sieling, P.A.1
-
77
-
-
0030043392
-
Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression
-
Gong, J.H., et al. 1996. Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression. Infect. Immun. 64:913-918.
-
(1996)
Infect. Immun.
, vol.64
, pp. 913-918
-
-
Gong, J.H.1
-
78
-
-
0032872122
-
CD4(+) T cell clones producing both interferon-gamma and interleukin-10 predominate in bronchoalveolar lavages of active pulmonary tuberculosis patients
-
Gerosa, F., et al. 1999. CD4(+) T cell clones producing both interferon-gamma and interleukin-10 predominate in bronchoalveolar lavages of active pulmonary tuberculosis patients. Clin. Immunol. 92:224-234.
-
(1999)
Clin. Immunol.
, vol.92
, pp. 224-234
-
-
Gerosa, F.1
-
79
-
-
0037188470
-
Antigen-specific and persistent tuberculin anergy in a cohort of pulmonary tuberculosis patients from rural Cambodia
-
Delgado, J.C., et al. 2002. Antigen-specific and persistent tuberculin anergy in a cohort of pulmonary tuberculosis patients from rural Cambodia. Proc. Natl. Acad. Sci. U. S. A. 99:7576-7581.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 7576-7581
-
-
Delgado, J.C.1
-
80
-
-
1642525626
-
Mycobacterium tuberculosis recall antigens suppress HIV-1 replication in anergic donor cells via CD8+ T cell expansion and increased IL-10 levels
-
Ranjbar, S., Ly, N., Thim, S., Reynes, J.M., and Goldfeld, A.E. 2004. Mycobacterium tuberculosis recall antigens suppress HIV-1 replication in anergic donor cells via CD8+ T cell expansion and increased IL-10 levels. J. Immunol. 172:1953-1959.
-
(2004)
J. Immunol.
, vol.172
, pp. 1953-1959
-
-
Ranjbar, S.1
Ly, N.2
Thim, S.3
Reynes, J.M.4
Goldfeld, A.E.5
-
81
-
-
0035424768
-
Blocking the receptor for IL-10 improves antimycobacterial chemotherapy and vaccination
-
Silva, RA, Pais, T.F., and Appelberg, R. 2001. Blocking the receptor for IL-10 improves antimycobacterial chemotherapy and vaccination. J. Immunol. 167:1535-1541.
-
(2001)
J. Immunol.
, vol.167
, pp. 1535-1541
-
-
Silva, R.A.1
Pais, T.F.2
Appelberg, R.3
-
82
-
-
0035863867
-
The role of IL-10 in promoting disease progression in leishmaniasis
-
Kane, M.M., and Mosser, D.M. 2001. The role of IL-10 in promoting disease progression in leishmaniasis. J. Immunol. 166:1141-1147.
-
(2001)
J. Immunol.
, vol.166
, pp. 1141-1147
-
-
Kane, M.M.1
Mosser, D.M.2
-
83
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid, Y., Piccirillo, C.A., Mendez, S., Shevach, E.M., and Sacks, D.L. 2002. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature. 420:502-507.
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
84
-
-
0036839677
-
Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy
-
Murray, H.W., et al. 2002. Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy. Infect. Immun. 70:6284-6293.
-
(2002)
Infect. Immun.
, vol.70
, pp. 6284-6293
-
-
Murray, H.W.1
-
85
-
-
0029156730
-
Secondary response to Listeria infection requires IFN-gamma but is partially independent of IL-12
-
Tripp, C.S., Kanagawa, O., and Unanue, E.R. 1995. Secondary response to Listeria infection requires IFN-gamma but is partially independent of IL-12. J. Immunol. 155:3427-3432.
-
(1995)
J. Immunol.
, vol.155
, pp. 3427-3432
-
-
Tripp, C.S.1
Kanagawa, O.2
Unanue, E.R.3
-
86
-
-
0035846326
-
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent
-
Keane, J., et al. 2001. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N. Engl. J. Med. 345:1098-1104.
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 1098-1104
-
-
Keane, J.1
-
87
-
-
0035064072
-
Immunology of tuberculosis
-
Flynn, J.L., and Chan, J. 2001. Immunology of tuberculosis. Annu. Rev. Immunol. 19:93-129.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 93-129
-
-
Flynn, J.L.1
Chan, J.2
-
88
-
-
0036127123
-
Local role for tumor necrosis factor alpha in the pulmonary inflammatory response to Mycobacterium tuberculosis infection
-
Smith, S., et al. 2002. Local role for tumor necrosis factor alpha in the pulmonary inflammatory response to Mycobacterium tuberculosis infection. Infect. Immun. 70:2082-2089.
-
(2002)
Infect. Immun.
, vol.70
, pp. 2082-2089
-
-
Smith, S.1
-
89
-
-
0036839650
-
In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions
-
Fenhalls, G., et al. 2002. In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions. Inject. Immun. 70:6330-6338.
-
(2002)
Inject. Immun.
, vol.70
, pp. 6330-6338
-
-
Fenhalls, G.1
-
90
-
-
0033545846
-
Tumor necrosis factor alpha is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system
-
Tsenova, L., Bergtold, A., Freedman, V.H., Young, R.A., and Kaplan, G. 1999. Tumor necrosis factor alpha is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system. Proc. Natl. Acad. Sci. U. S. A. 96:5657-5662.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 5657-5662
-
-
Tsenova, L.1
Bergtold, A.2
Freedman, V.H.3
Young, R.A.4
Kaplan, G.5
-
92
-
-
0035914841
-
The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure
-
Belkaid, Y., et al. 2001. The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J. Exp. Med. 194:1497-1506.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1497-1506
-
-
Belkaid, Y.1
-
93
-
-
0037136284
-
Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis
-
Kullberg, M.C., et al. 2002. Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis. J. Exp. Med. 196:505-515.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 505-515
-
-
Kullberg, M.C.1
-
94
-
-
0034967640
-
Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells
-
Suri-Payer, E., and Cantor, H. 2001. Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J. Autoimmun. 16:115-123.
-
(2001)
J. Autoimmun.
, vol.16
, pp. 115-123
-
-
Suri-Payer, E.1
Cantor, H.2
-
95
-
-
0038215374
-
Tolerance, DCs and tryptophan: Much ado about IDO
-
Grohmann, U., Fallarino, F., and Puccetti, P. 2003. Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol. 24:296-297.
-
(2003)
Trends Immunol.
, vol.24
, pp. 296-297
-
-
Grohmann, U.1
Fallarino, F.2
Puccetti, P.3
-
96
-
-
0842286646
-
IDO and tolerance to tumors
-
Munn, D.H., and Mellor, A.L. 2004. IDO and tolerance to tumors. Trends Mol. Med. 10:15-18.
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 15-18
-
-
Munn, D.H.1
Mellor, A.L.2
-
97
-
-
0035284804
-
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
-
Annacker, O., et al. 2001. CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10. J. Immunol. 166:3008-3018.
-
(2001)
J. Immunol.
, vol.166
, pp. 3008-3018
-
-
Annacker, O.1
-
98
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann, T.R., and Coffman, R.L. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
99
-
-
0034694028
-
Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only in the presence of lipopolysaccharide
-
Castro, A.G., et al. 2000. Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only in the presence of lipopolysaccharide. J. Exp. Med. 192:1529-1534.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1529-1534
-
-
Castro, A.G.1
-
100
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton, A.M., and Shevach, E.M. 1998. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287-296.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
102
-
-
0042971652
-
Tolerogenic dendritic cells
-
Steinman, R.M., Hawiger, D., and Nussenzweig, M.C. 2003. Tolerogenic dendritic cells. Annu. Rev. Immunol. 21:685-711.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 685-711
-
-
Steinman, R.M.1
Hawiger, D.2
Nussenzweig, M.C.3
-
103
-
-
0025607864
-
Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide
-
Goldfeld, A., Doyle, C, and Maniatis, T. 1990. Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide. Proc. Natl. Acad. Sci. U. S. A. 87:9769-9773.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 9769-9773
-
-
Goldfeld, A.1
Doyle, C.2
Maniatis, T.3
-
104
-
-
0345128099
-
Coordinate viral induction of tumor necrosis factor alpha and interferon beta in human B cells and monocytes
-
Goldfeld, A.E., and Maniatis, T. 1989. Coordinate viral induction of tumor necrosis factor alpha and interferon beta in human B cells and monocytes. Proc. Natl. Acad. Sci. U. S. A. 86:1490-1494.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 1490-1494
-
-
Goldfeld, A.E.1
Maniatis, T.2
-
105
-
-
0029071930
-
Analysis of lymphocyte costimulation in vivo using transgenic and 'knock-out' mice
-
Sharpe, A.H. 1995. Analysis of lymphocyte costimulation in vivo using transgenic and 'knock-out' mice. Curr. Opin. Immunol. 7:389-395.
-
(1995)
Curr. Opin. Immunol.
, vol.7
, pp. 389-395
-
-
Sharpe, A.H.1
|