The role of DNA damage and repair in aging through the prism of Koch-like criteria

Ageing Research Reviews

Volumn 12, Issue 2, 2013, Pages 661-684

  Moskalev, Alexey A ^a   Shaposhnikov, Mikhail V ^a   Plyusnina, Ekaterina N ^a   Zhavoronkov, Alex ^b,c   Budovsky, Arie ^d,e   Yanai, Hagai ^d   Fraifeld, Vadim E ^d  

^a INSTITUTE OF BIOLOGY   (Russian Federation)

^b Bioinformatics Laboratory   (Russian Federation)

^c Biogerontology Research Foundation   (United Kingdom)

^d Judea Regional Research and Development Center   (Israel)

^e BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Aging; DNA damage; DNA mutations; DNA repair; Longevity

Indexed keywords

CELL NUCLEUS DNA;

AGING; ANEUPLOIDY; CHROMOSOME ABERRATION; CHROMOSOME INSERTION; CHROMOSOME TRANSLOCATION; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EPIGENETICS; GENE EXPRESSION; GENE SILENCING; GENOMIC INSTABILITY; HUMAN; LONGEVITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POINT MUTATION; PRISM; REVIEW; SIGNAL TRANSDUCTION; SINGLE STRANDED DNA BREAK; SOMATIC MUTATION; STEM CELL;

AGING; AGING, PREMATURE; ANIMALS; CELL AGING; CLONAL EVOLUTION; DNA DAMAGE; DNA REPAIR; HUMANS; LONGEVITY; MODELS, GENETIC; MUTAGENESIS; MUTAGENS; MUTATION; STEM CELLS;

EID: 84878552183     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2012.02.001     Document Type: Review

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