Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene

Molecular and Cellular Biology

Volumn 19, Issue 3, 1999, Pages 2366-2372

  Harada, Yoshi Nobu ^a   Shiomi, Naoko ^a   Koike, Manabu ^a   Ikawa, Masahito ^b   Okabe, Masaru ^b   Hirota, Seiichi ^c   Kitamura, Yukihiko ^c   Kitagawa, Masanobu ^d   Matsunaga, Tsukasa ^e   Nikaido, Osamu ^e   Shiomi, Tadahiro ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE;

ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CELL SURVIVAL; COCKAYNE SYNDROME; EMBRYO; GENE ISOLATION; GROWTH DISORDER; GROWTH RETARDATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LIFESPAN; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; SENESCENCE; XERODERMA PIGMENTOSUM;

ANIMALIA;

EID: 0032980573     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.3.2366     Document Type: Article

References (49)

1. Aboussekhra, A., and R. D. Wood. 1994. Repair of UV-damaged DNA by mammalian cells and Saccharomyces cerevisiae. Curr. Opin. Genet. Dev. 4:212-220.
2. Brookman, K. W., J. E. Lamerdin, M. P. Thelen, M. Hwang, J. T. Reardon, A. Sancar, Z.-Q. Zhou, C. A. Walter, C. N. Parris, and L. H. Thompson. 1996. ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs. Mol. Cell. Biol. 16:6553-6562.
3. Broughton, B. C., A. F. Thompson, S. A. Harcourt, W. Vermeulen, J. H. J. Hoeijmakers, E. Botta, M. Stefanini, M. D. King, C. A. Weber, and J. Cole. 1995. Molecular and cellular analysis of the DNA repair defect in a patient with xeroderma pigmentosum complementation group D who has the clinical features of xeroderma pigmentosum and Cockayne syndrome. Am. J. Hum. Genet. 56:167-174.
4. Cleaver, J. E., and K. H. Kraemer. 1995. Xeroderma pigmentosum and Cockayne syndrome, p. 4393-4419. In C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle (ed.), The metabolic basis of inherited disease. McGraw-Hill Press, New York, N.Y.
5. Cloud, K. G., B. Shen, G. F. Strniste, and M. S. Park. 1995. XPG protein has a structure-specific endonuclease activity. Mutat. Res. 347:55-60.
6. Cooper, P. K., T. Nouspikel, S. G. Clarkson, and S. A. Leadon. 1997. Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G. Science 275:990-993.
7. de Boer, J., I. Donker, J. de Wit, J. H. J. Hoeijmakers, and W. Weeda. 1998. Disruption of the mouse xeroderma pigmentosum group D DNA repair/ basal transcription gene results in preimplantation lethality. Cancer Res. 58:89-94.
8. de Boer, J., J. De Wit, H. Van Steeg, R. J. W. Berg, H. Morreau, P. Visser, A. R. Lehmann, M. Duran, J. H. J. Hoeijmaders, and G. Weeda, 1998. A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy. Mol. Cell 1:981-990.
9. Demple, B., and L. Harrison. 1994. Repair of oxidative damage to DNA: enzymology and biology. Annu. Rev. Biochem. 63:915-943.
10. de Vries, A., C. T. van Oostrom, F. M. Hofhuis, P. M. Dortant, R. J. Berg, F. R. de Gruijl, P. W. Wester, C. F. van Kreijl, P. J. Capel, H. van Steeg, and S. J. Verbeek. 1995. Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA. Nature 377:169-173.
11. Drapkin, R., J. T. Reardon, A. Ansarl, J. C. Huang, L. Zawel, K. Ahn, A. Sancar, and D. Reinberg. 1994. Dual role of TFIIH in DNA excision repair and transcription by RNA polymerase II. Nature 368:769-772.
12. Finlay, C. A., P. W. Hinds, T.-H. Tan, D. Eliyahu, M. Oren, and A. J. Levine. 1988. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol. Cell. Biol. 8:531-539.
13. Friedberg, E. C., G. C. Walker, and W. Siede. 1995. DNA repair and mutagenesis. p. 655-658. ASM Press, Washington, D.C.
14. Friedberg, E. C. 1996. Cockayne syndrome - a primary defect in DNA repair, transcription, both or neither? Bioessays 18:731-738.
15. Gubbay, J., N. Vivian, A. Economou, D. Jackson, P. Goodfellow, and R. Lovell-Badge. 1992. Inverted repeat structure of the Sry locus in mice. Proc. Natl. Acad. Sci. USA 89:7953-7957.
16. Hamel, B. C. J., A. Raams, A. R. Shuitema-Dijkstra, P. Simons, I. Van der Burgt, N. G. J. Jaspers, and W. J. Kieijer. 1996. Xeroderma pigmentosum-Cockayne syndrome complex: a further case. J. Med. Genet. 33:607-610.
17. Hanawalt, P. C. 1994. Transcription-coupled repair and human disease. Science 266:1957-1958.
18. Harada, Y.-N., Y. Matsuda, N. Shiomi, and T. Shiomi. 1995. Complementary DNA sequence and chromosomal localization of xpg, the mouse counterpart of human repair gene XPG/ERCC5. Genomics 28:59-65.
19. Harrington, J. J., and M. R. Lieber. 1994. Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair. Genes Dev. 8:1344-1355.
20. Harvey, D. M., and A. J. Levine. 1991. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblast. Genes Dev. 5:2375-2385.
21. Henning, K. A., L. Li, N. Iyer, L. D. McDaniel, M. S. Reagan, R. Legerski, R. A. Schultz, M. Stefanini, A. R. Lehmann, L. V. Mayne, and E. C. Friedberg. 1995. The Cockayne syndrome group A encodes a WD-repeat protein which interacts with CSB protein and a subunit of RNA pol II transcription factor IIH. Cell 82:555-564.
22. Kaul, S. C., R. Wadhwa, T. Sugihara, K. Obuchi, Y. Komatsu, and Y. Mitsui. 1994. Identification of genetic events involved in early steps of immortalization of mouse fibroblasts. Biochim. Biophys. Acta 1201:389-396.
23. Legerski, R., and C. Peterson. 1992. Expression cloning of a human DNA repair gene involved in xeroderma pigmentosum group C. Nature 359:70-73.
24. Lehmann, A. R. 1995. Nucleotide excision repair and the link with transcription. Trends Biochem. Sci. 20:402-405.
25. Ludwig, D. L., J. S. Mudgett, M. S. Park, A. V. Perez-Castro, and M. A. MacInnes. 1996. Molecular cloning and structural analysis of the functional mouse genomic XPG gene. Mamm. Genome 7:644-649.
26. Matsunaga, T., D. Mu, C. H. Park, J. T. Reardon, and A. Sancar. 1995. Human DNA repair excision nuclease: analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC 1 antibodies. J. Biol. Chem. 270:20862-20869.
27. Matsunaga, T., C. H. Park, T. Bessho, D. Mu, and A. Sancar. 1996. Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease. J. Biol. Chem. 271:11047-11050.
28. Mizuno, T., T. Matsunaga, M. Ihara, and O. Nikaido. 1991. Establishment of a monoclonal antibody recognizing cyclobutane-type thymine dimers in DNA: a comparative study with 64M1 antibody specific for (6-4) photoproducts. Mutat. Res. 254:175-184.
29. Moriwaki, S.-I., M. Stefanini, A. R. Lehmann, J. H. J. Hoeijmakers, J. H. Robbins, I. Rapin, E. Botta, B. Tanganelli, W. Vermeulen, B. C. Broughton, and K. H. Kraemer. 1996. DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and Cockayne syndrome resemble xeroderma pigmentosum cells. J. Investig. Dermatol. 107:647-653.
30. Mu, D., C. H. Park, T. Matunaga, D. S. Hsu, J. T. Reardon, and A. Sancar. 1995. Reconstitution of human DNA repair excision nuclease in a highly defined system. J. Biol. Chem. 270:2415-2418.
31. Mu, D., D. S. Hsu, and A. Sancar. 1996. Reaction mechanism of human DNA repair excision nuclease. J. Biol. Chem. 271:8285-8294.
32. Nakane, H., S. Takeuchi, S. Yuba, M. Saijo, Y. Nakatsu, H. Murai, Y. Nakatsuru, T. Ishikawa, S. Hirota, Y. Kitamura, Y. Kato, Y. Tsunoda, H. Miyauchi, T. Horio, T. Tokunaga, T. Matsunaga, O. Nikaido, Y. Nishimune, Y. Okada, and K. Tanaka. 1995. High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene. Nature 377:165-168.
33. Nance, M. A., and S. A. Berry. 1992. Cockayne syndrome: review of 140 cases. Am. J. Med. Genet. 42:68-84.
34. Nouspikel, T., P. Lalle, S. A. Leadon, P. K. Cooper, and S. G. Clarkson. 1997. A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: implication for a second XPG function. Proc. Natl. Acad. Sci. USA 94:3116-3121.
35. O'Donovan, A., A. A. Davis, J. G. Moggs, S. C. West, and R. D. Wood. 1994. XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair. Nature 371:432-435.
36. O'Donovan, A., D. Scherly, S. G. Clarkson, and R. D. Wood. 1994. Isolation of active recombinant XPG protein, a human DNA repair endonuclease. J. Biol. Chem. 269:15965-15968.
37. Sancar, A. 1996. DNA excision repair. Annu. Rev. Biochem. 65:43-81.
38. Satoh, M. S., and P. C. Hanawalt. 1997. Competent transcription initiation by RNA polymerase II in cell-free extracts from xeroderma pigmentosum groups B and D in an optimized RNA transcription assay. Biochim. Biophys. Acta 1354:241-251.
39. Scherly, D., T. Nouspikel, J. Corlet, C. Ucla, A. Bairoch, and S. G. Clarkson. 1993. Complementation of the DNA repair defect in xeroderma pigmentosum group G cells by a human cDNA related to yeast RAD2. Nature 363: 182-185.
40. Shaeffer, L., R. Roy, S. Humbert, V. Moncollin, W. Vermeulen, J. H. J. Hoijmakers, P. Chambon, and J. M. Egly. 1993. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science 260:58-63.
41. Shiomi, T., Y.-N. Harada, T. Saite, N. Shiomi, V. Okuno, and M. Yamaizumi. 1994. An ERCC5 gene with homology to yeast RAD2 is involved in group G xeroderma pigmentosum. Mutat. Res. 314:167-175.
42. Sijbers, A. M., W. L. De Laat, R. R. Ariza, M. Biggerstaff, Y.-F. Wei, J. G. Moggs, K. C. Carter, B. K. Shell, E. Evans, M. C. De Jong, S. Rademakers, J. De Rooij, N. G. J. Jaspers, J. H. J. Hoeijmakers, and R. D. Wood. 1996. Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease. Cell 86:811-822.
43. Tanaka, K., I. Satokata, Z. Ogita, T. Uchida, and Y. Okada. 1989. Molecular cloning of a mouse DNA repair gene that complements the defect of group-A xeroderma pigmentosum. Proc. Natl. Acad. Sci. USA 86:5512-5516.
44. Troelstra, C., A. van Gool, J. de Wit, W. Vermeulen, D. Bootsma, and J. H. J. Hoeijmakers. 1992. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell 71:939-953.
45. Van der Horst, G. T. J., H. van Steeg, R. J. W. Berg, A. J. van Gool, J. de Wit, G. Weeda, H. Morreau, R. B. Beems, C. F. van Kreijl, F. R. de Gruijl, D. Bootsma, and J. H. J. Hoeijmakers. 1997. Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition. Cell 89:425-435.
46. Vermeulen, W., J. Jaeken, N. G. Jaspers, D. Bootsma, and J. H. J. Hoeijmakers. 1993. Xeroderma pigmentosum complementation group G associated with Cockayne syndrome. Am. J. Hum. Genet. 53:185-192.
47. Vermeulen, W., R. J. Scott, S. Rodgers, H. J. Muller, J. Cole, C. F. Arlett, W. J. Kleijer, D. Bootsma, J. H. J. Hoeijmakers, and G. Weeda. 1994. Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3. Am. J. Hum. Genet. 54:191-200.
48. Weber, C. A., E. P. Salazar, S. A. Stewart, and L. H. Thompson. 1988. Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells. Mol. Cell. Biol. 8:1137-1146.
49. Weeda, G., R. C. A. van Ham, R. Masurel, A. Westerveld, H. Odijk, J. de Wit, D. Bootsma, A. J. van der Eb, and J. H. J. Hoeijmakers. 1990. Molecular cloning and biological characterization of the human excision repair gene ERCC-3. Mol. Cell. Biol. 10:2570-2581.