Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss

Cell Stem Cell

Volumn 1, Issue 1, 2007, Pages 113-126

  Ruzankina, Yaroslava ^a   Pinzon Guzman, Carolina ^a   Asare, Amma ^a   Ong, Tony ^a   Pontano, Laura ^a   Cotsarelis, George ^b   Zediak, Valerie P ^b   Velez, Marielena ^b   Bhandoola, Avinash ^b   Brown, Eric J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

DNA; STEMCELL

Indexed keywords

ATR PROTEIN;

AGING; ALOPECIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; GENE DELETION; GENETIC ANALYSIS; HAIR COLOR; HEART MUSCLE FIBROSIS; HISTOPATHOLOGY; HOMEOSTASIS; INVOLUTION; KIDNEY FIBROSIS; KYPHOSIS; MOUSE; NONHUMAN; OSTEOPOROSIS; PHENOTYPE; PRIORITY JOURNAL; SPERMATOGENESIS; STEM CELL; TISSUE REGENERATION; TRANSGENIC MOUSE;

AGING; ANIMALS; CELL CYCLE PROTEINS; GENES, ESSENTIAL; MICE; MICE, KNOCKOUT; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; STEM CELLS;

MUS;

EID: 34249885603     PISSN: 19345909     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stem.2007.03.002     Document Type: Article

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