Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CPG island context

PLoS Genetics

Volumn 5, Issue 8, 2009, Pages

  Christensen, Brock C ^a,b   Houseman, E Andres ^b,c   Marsit, Carmen J ^a   Zheng, Shichun ^d   Wrensch, Margaret R ^d   Wiemels, Joseph L ^d   Nelson, Heather H ^e   Karagas, Margaret R ^f   Padbury, James F ^b   Bueno, Raphael ^g   Sugarbaker, David J ^g   Yeh, Ru Fang ^d   Wiencke, John K ^d   Kelsey, Karl T ^a,b  

^a BROWN UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

^f DARTMOUTH MEDICAL SCHOOL   (United States)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ARTICLE; CORRELATION ANALYSIS; CPG ISLAND; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; EPIGENETICS; GENE EXPRESSION; GENE LOCUS; GENETIC REGULATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; PLASTICITY; TISSUE SPECIFICITY; ADULT; AGE; AGED; ANTIBODY SPECIFICITY; FEMALE; GENETIC EPIGENESIS; GENETICS; MALE; MIDDLE AGED; NEWBORN;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; CPG ISLANDS; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; EPIGENESIS, GENETIC; FEMALE; HUMANS; INFANT, NEWBORN; MALE; MIDDLE AGED; ORGAN SPECIFICITY;

EID: 70149099610     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000602     Document Type: Article

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