Checkpoint proteins control survival of the postmitotic cells in Caenorhabditis elegans

Science

Volumn 312, Issue 5778, 2006, Pages 1381-1385

  Olsen, Anders ^a   Vantipalli, Maithili C ^a   Lithgow, Gordon J ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; CELL CULTURE; DNA; PROTEINS;

CAENORHABDITIS ELEGANS; POSTMITOTIC ADULT CELLS; SOMATIC MAINTENANCE;

CELLS;

CELL PROTEIN; PROTEIN CID 1; UNCLASSIFIED DRUG;

DNA; NEMATODE; PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; CELL DIVISION; CELL SURVIVAL; DNA DAMAGE; GENE CONTROL; NONHUMAN; PRIORITY JOURNAL; STRESS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL CYCLE PROTEINS; CELL SURVIVAL; HEAT-SHOCK PROTEINS; MITOSIS; MUTATION; PROTEIN KINASES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SIGNAL TRANSDUCTION; STEM CELLS;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 33744828285     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1124981     Document Type: Article

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29. We thank M. Benedetti and A. Foster for help with the UCN-01 thermotolerance assays; M. Lund and the members of the Lithgow Laboratory, the Kapahi Laboratory, J. Campisi, C. Benz, and D. Bhaumik for helpful discussions; and J. Ahringer and the Medical Research Council gene service for providing the RNAi library. UCN-01 was made available from the Drug Synthesis and Chemistry Branch, Developmental Therapeutics Program, National Cancer Institute. A.O. was supported by the Danish Research Academy and the Danish Cancer Society. G.J.L. was supported by NIH AG21069, AG22868, and NS050789-01; the Ellison Medical Foundation; the Glenn Foundation for Medical Research; the Biotechnology and Biological Sciences Research Council, Science of Ageing Initiative; and the Herbert Simon Family Medical Foundation.