The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 6, 2006, Pages 1864-1869

  Vartanian, Vladimir ^a   Lowell, Brian ^a   Minko, Irina G ^a   Wood, Thomas G ^b   Ceci, Jeffrey D ^b   George, Shakeeta ^c   Ballinger, Scott W ^c   Corless, Christopher L ^d   McCullough, Amanda K ^a   Lloyd, R Stephen ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c University of Alabama at Birmingham   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

DNA repair; Fatty liver disease; Mitochondria; Obesity; Oxidative stress

Indexed keywords

CELL NUCLEUS DNA; DNA GLYCOSYLTRANSFERASE; MITOCHONDRIAL DNA; PROTEIN NEIL1; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER; CARDIOVASCULAR DISEASE; CATARACTOGENESIS; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; DNA DAMAGE; DYSLIPIDEMIA; ENZYME ACTIVITY; EXCISION REPAIR; FATTY LIVER; FEMALE; GENE DELETION; GENOMIC INSTABILITY; HETEROZYGOTE; HYPERINSULINEMIA; HYPERTENSION; KNOCKOUT GENE; KNOCKOUT MOUSE; MALE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEADY STATE;

ANIMALS; DNA DAMAGE; DNA GLYCOSYLASES; DNA, MITOCHONDRIAL; FATTY LIVER; FEMALE; GENE DELETION; HYPERINSULINISM; HYPERLIPIDEMIAS; KIDNEY; LEPTIN; MALE; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY; PEDIGREE;

ANIMALIA; ESCHERICHIA COLI; MAMMALIA;

EID: 32444434993     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0507444103     Document Type: Article

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