Vitamin E and genome stability

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 475, Issue 1-2, 2001, Pages 37-44

  Claycombe, Kate J ^a   Meydani, Simin Nikbin ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

DNA damage; Genome; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BIOLOGICAL MARKER; CELL DNA; ENDONUCLEASE; FREE RADICAL; PEROXY RADICAL; REACTIVE OXYGEN METABOLITE; SCAVENGER;

APOPTOSIS; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; DIETARY INTAKE; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; GENE EXPRESSION; GENE POOL; GENETIC STABILITY; GENOTOXICITY; HUMAN; MICRONUCLEUS; MUTAGENIC ACTIVITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW;

ANIMALS; DIETARY SUPPLEMENTS; DNA; DNA DAMAGE; HUMANS; NUTRITION POLICY; VITAMIN E;

EID: 0035906325     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(01)00077-X     Document Type: Review

References (65)

1. Identification of possible reactive oxygen species involved in ultraviolet radiation-induced oxidative DNA damage
2. Exposure to cigarette smoke increases apoptosis in the rat gastric mucosa through a reactive oxygen species-mediated and p53-independent pathway
3. Yeast superoxide dismutase mutants reveal a pro-oxidant action of weak organic acid food preservatives
4. Micronutrients prevent cancer and delay aging
5. In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in xeroderma pigmentosum patients
6. Effect of Vitamin E on chromosomal aberrations in lymphocytes from patients with Down's syndrome
7. Vitamin E reduces chromosomal damage and inhibits hepatic tumor formation in a transgenic mouse model
8. Effects of high doses of Vitamins C and E against doxorubicin-induced chromosomal damage in Wistar rat bone marrow cells
9. Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals
10. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems
11. Modifying effect of Vitamins C, E and beta-carotene against gamma-ray-induced DNA damage in mouse cells
12. Rapid and sensitive detection of hydroxyl radicals formed by activated neutrophils in the presence of chelated iron: Hydroxylation of deoxyguanosine to 8-hydroxydeoxyguanosine
13. Response of human oral epithelial cells to oxidative damage and the effect of Vitamin E
14. 2- and MNNG-treated mammalian cells by the comet assay
15. Free radical chemistry of cigarette smoke and its implication in human cancer
16. The influence of antioxidants on cigarette smoke-induced DNA single-strand breaks in mouse organs: A preliminary study with the alkaline single cell gel electrophoresis assay
17. Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite
18. Cigarette smoke induces DNA single-strand breaks in human cells
19. Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major
20. Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage
21. Nitric oxide and peroxynitrite released by ultraviolet B-irradiated human endothelial cells are possibly involved in skin erythema and inflammation
22. Endothelial cell nitric oxide production in acute chest syndrome
23. Mutations induced by reactive nitrogen oxide species in the supF forward mutation assay
24. Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination
25. DNA damage by peroxynitrite characterized with DNA repair enzymes
26. Suppression of nitric oxide toxicity in islet cells by alpha-tocopherol
27. 3
28. Naphthalene-induced oxidative stress in rats and the protective effects of Vitamin E succinate
29. Disruption of redox homeostasis in the transforming growth factor-alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis
30. Radioprotective effect of Vitamins C and E
31. Effects of Vitamin E, Vitamin B2 and selenite on DNA single strand breaks induced by sodium chromate (VI)
32. Protective effect of Vitamin E against chromosomal aberrations and mutation induced by sodium chromate in Chinese hamster V79 cells
33. Induction of apoptotic cell death by particulate lead chromate: Differential effects of Vitamins C and E on genotoxicity and survival
34. Antioxidant actions of plant foods: Use of oxidative DNA damage as a tool for studying antioxidant efficacy
35. Ascorbate and alpha-tocopherol prevent apoptosis induced by serum removal independent of Bcl-2
36. Oxidative stress-induced apoptosis prevented by Trolox
37. Inhibition by tocopherol of prostaglandin-induced apoptosis in ovine corpora lutea
38. Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
39. Direct evidence for antioxidant effect of Bcl-2 in PC12 rat pheochromocytoma cells
40. Vitamins C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax
41. Induction of a SOS repair system in lysogenic bacteria by zearalenone and its prevention by Vitamin E
42. Effects of dietary polyunsaturated fats and Vitamin E on aging and peroxidative damage to DNA
43. Transcriptional inhibition by carcinogenic chromate: Relationship to DNA damage
44. Protective effect of alpha-tocopherol in carrier liposomes on ultraviolet-mediated human epidermal cell damage in vitro
45. Activation of AP-1 and nuclear factor-kappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes
46. c-fos is involved in the cellular defence against the genotoxic effect of UV radiation
47. Involvement of activator protein-1 (AP-1) in induction of apoptosis by Vitamin E succinate in human breast cancer cells
48. Antioxidants stimulate transcriptional activation of the c-fos gene by multiple pathways in human fetal lung fibroblasts (WI-38)
49. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm
50. Immunocompetence and oxidant defense during ascorbate depletion of healthy men
51. Novel repair action of Vitamin C upon in vivo oxidative DNA damage
52. The effects of antioxidant supplementation during Percoll preparation on human sperm DNA integrity
53. Effect of antioxidant vitamin supplementation on DNA damage and repair in human lymphoblastoid cells
54. The effect of increased intakes of polyunsaturated fatty acids and Vitamin E on DNA damage in human lymphocytes
55. Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes
56. Inhibition of oxidative DNA damage, 8-OHdG, and carbonyl contents in smokers treated with antioxidants (Vitamin E, Vitamin C, beta-carotene and red ginseng)
57. Effects of beta-carotene and alpha-tocopherol on bleomycin-induced chromosomal damage
58. Vitamin-E supplements and their effect on vitamin-E status in blood and genetic damage rate in peripheral blood lymphocytes
59. Vitamin E supplementation and oxidative damage to DNA and plasma LDL in type 1 diabetes
60. No effect of supplementation with Vitamin E, ascorbic acid, or coenzyme Q10 on oxidative DNA damage estimated by 8-oxo-7, 8-dihydro-2′-deoxyguanosine excretion in smokers
61. Oxidative DNA damage in human lymphocytes: Correlations with plasma levels of alpha-tocopherol and carotenoids
62. The influence of alpha-tocopherol and pyritinol on oxidative DNA damage and lipid peroxidation in human lymphocytes
63. Carcinogen-induced chromosomal breakage decreased by antioxidants
64. 2+-dependent DNA damage in human peripheral blood lymphocytes