Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice

PLoS Genetics

Volumn 2, Issue 12, 2006, Pages 2013-2025

  Van De Ven, Marieke ^a   Andressoo, Jaan Olle ^a,c   Holcomb, Valerie B ^b   Von Lindern, Marieke ^a   Jong, Willeke M C ^a   De Zeeuw, Chris I ^a   Suh, Yousin ^b   Hasty, Paul ^b   Hoeijmakers, Jan H J ^a   Van Der Horst, Gijsbertus T J ^a   Mitchell, James R ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GROWTH HORMONE; SOMATOMEDIN C;

ADAPTIVE BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CALORIC RESTRICTION; CELL AGING; CONTROLLED STUDY; DISEASE COURSE; DWARFISM; EMBRYO; EXCISION REPAIR; GENOMIC INSTABILITY; GLUCOSE BLOOD LEVEL; HETEROZYGOSITY; HYPOGLYCEMIA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; POSTNATAL DEVELOPMENT; PROGERIA; AGING; ANIMAL; C57BL MOUSE; CELL DEATH; DNA REPAIR; FIBROBLAST; GENETICS; GROWTH HORMONE SECRETING CELL; HETEROZYGOTE; LONGEVITY; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; PURKINJE CELL;

ATAXIA;

AGING; ANIMALS; CALORIC RESTRICTION; CELL DEATH; DNA REPAIR; DWARFISM; FIBROBLASTS; GENOMIC INSTABILITY; HETEROZYGOTE; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; OXIDATIVE STRESS; PROGERIA; PURKINJE CELLS; SOMATOTROPHS;

EID: 33845611248     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0020192     Document Type: Article

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