P53 mutant mice that display early ageing-associated phenotypes

Nature

Volumn 415, Issue 6867, 2002, Pages 45-53

  Tyner, Stuart D ^a   Venkatachalam, Sundaresan ^a   Choi, Jene ^a   Jones, Stephen ^b   Ghebranious, Nader ^c   Igelmann, Herbert ^d   Lu, Xiongbin ^a   Soron, Gabrielle ^a   Cooper, Benjamin ^a   Brayton, Cory ^a   Sang, Hee Park ^a   Thompson, Timothy ^a   Karsenty, Gerard ^a   Bradley, Allan ^a,e   Donehower, Lawrence A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c MARSHFIELD CLINIC   (United States)

^d LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^e WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MUTAGENESIS; RNA; TUMORS;

AGEING-ASSOCIATED PHENOTYPES;

CELLS;

PROTEIN P53;

AGING; GENE; MUTATION;

AGING; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA DAMAGE; GENE DELETION; GENE INACTIVATION; GENE MUTATION; LONGEVITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TEMPERATURE SENSITIVE MUTANT; TRANSGENIC MOUSE; TUMOR SUPPRESSOR GENE;

ADIPOSE TISSUE; AGING; AGING, PREMATURE; ALLELES; ANIMALS; BODY WEIGHT; BONE AND BONES; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; EXONS; FEMALE; GENES, P53; HAIR; LONGEVITY; MALE; MICE; MICE, TRANSGENIC; NEOPLASMS; ORGAN SIZE; OSTEOPOROSIS; PHENOTYPE; RNA, MESSENGER; SEQUENCE DELETION; SKIN; TUMOR SUPPRESSOR PROTEIN P53; WOUND HEALING;

ANIMALIA; MUS MUSCULUS;

EID: 0037011958     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/415045a     Document Type: Article

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