Expression changes in DNA repair enzymes and mitochondrial DNA damage in aging rat lens

Molecular Vision

Volumn 16, Issue , 2010, Pages 1754-1763

  Zhang, Yi ^a   Zhang, Lu ^a   Zhang, Lan ^a   Bai, Jie ^a   Ge, Hong Yan ^a   Liu, Ping ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 HYDROXYGUANINE; CELL NUCLEUS DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE 1; DNA DIRECTED DNA POLYMERASE GAMMA; DNA GLYCOSYLTRANSFERASE; GENOMIC DNA; MESSENGER RNA; MITOCHONDRIAL DNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATARACT; CONTROLLED STUDY; DNA DAMAGE; DNA ISOLATION; EPITHELIUM CELL; EXCISION REPAIR; GENE EXPRESSION; GENE LOCATION; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; LENS EPITHELIUM; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE STUDY; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AGING; ANIMALS; CELL NUCLEUS; DEOXYGUANOSINE; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA, MITOCHONDRIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IMMUNOHISTOCHEMISTRY; LENS, CRYSTALLINE; MALE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE DELETION;

EID: 77956958964     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Gottipati S, Cammarata PR. Mitochondrial superoxide dismutase activation with 17β-estradiol-treated human lens epithelial cells. Mol Vis 2008; 14:898-905.
2. Ozmen B, Ozmen D, Erkin E. Lens superoxide dismutase and catalase activeties in diabetic cataract. Clin Biochem 2002; 35:69-72.
3. Bantseev VL, Herbert T, Trevithick JR, Sivak JG. Mitochondria of rat lenses: Distribution near and at the sutures. Curr Eye Res 1999; 19:506-516.
4. Bantseev V, McCanna D, Banh A, Wong WW, Moran KL, Dixon DG. Mechanisms of ocular toxicity using the in vitro bovine lens and sodium dodecyl sulfate as a chemical model. Toxicol Sci 2003; 73:98-107.
5. Huang L, Yappert MC, Jumblatt MM, Borchman D. Hyperoxia and thyroxine treatment and the relationships between reactive oxygen species generation, mitochondrial membrane potential and cardiolipin in human lens epithelial cell cultures. Curr Eye Res 2008; 33:575-586.
6. Conlon KA, Zarkov DO, Berrios M. Immunofluorescent localization of the murine 8-oxoguanine DNA glycosylase (mOGG1) in cells growing under normal and nutrient deprivation conditions. DNA Repair (Amst) 2003; 2:1337-1352.
7. Chen D, Lan J, Pei W, Chen J. Detection of DNA base-excision repair activity for oxidative lesions in adult rat brain mitochondria. J Neurosci Res 2000; 61:225-236.
8. Jarrett SG, Liang LP, Hellier JL, Staley KJ, Patel M. Mitochondrial DNA damage and impaired base excision repair during epilepto genesis. Neurobiol Dis 2008; 30:130-138.
9. Mandavilli BS, Santos JH, Van Houten B. Mitochondrial DNA repair and aging. Mutat Res 2002; 509:127-151.
10. Li P, Nijhawan D, Budihardjo I, Rinivasula SM, Ahmad M, Alnemri ES, Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91:479-489.
11. Yao K, Ye PP, Zhang L, Tan J, Tang XJ, Zhang YD. Epigallocatechin gallate protects against oxidative stressinduced mitochondria depen-dent apoptosis in human lens epithelial cells. Mol Vis 2008; 14:217-223.
12. Hursting SD, Lavigne JA, Berrigan D, Perkins SN, Barrett JC. Calorie restriction, aging and cancer prevention:mechanisms of action and applicability to humans. Annu Rev Med 2003; 54:131-152.
13. Mattson MP, Chan SL, Duan W. Modification of brain aging and neurodegenera-tive disorders by genes, diet and behaviorr. Physiol Rev 2002; 82:637-672.
14. Stuart JA, Karahalil B, Hogue BA, Souza-Pinto NC, Bohr VA. Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction. FASEB J 2004; 18:595-597.
15. Stevnsner T, Thorslund T, de Souza-Pinto NC, Bohr VA, Jordan N, Reddy V, Le K, Douglas C, Wallace M, Kenney C. Mitochondrial repair of 8-oxoguanine and changes with aging. Exp Gerontol 2002; 37:1189-1196.
16. Atilano SR, Coskun P, Chwa M. Accumulation of mitochondrial DNA damage in keratoconus corneas. Invest Ophthalmol Vis Sci 2005; 46:1256-1263.
17. Santos JH, Hunakova L, Chen Y. Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death. J Biol Chem 2003; 278:1728-1734.
18. Huang L, Tang D, Marta C. Oxidation-induced changes in human lens epithelial cells 2. Mitochondria and the generation of reactive oxygen species. Free Radic Biol Med 2006; 41:926-936.
19. Wang AL, Lukas TJ, Yuan M. Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid. Mol Vis 2008; 14:644-651.
20. Santos JH, Meyer JN, Mandavilli BS, Van Houten B. Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol Bio 2006; 314:183-199.
21. Ihrig J, Lill R, Muhlenhoff U. Application of the DNA-specific dye EvaGreen for the routine quantification of DNA in microplates. Anal Biochem 2006; 359:265-267.
22. Mao F, Leung WY, Xin X. Characterization of EvaGreen and the implication of its physicochemical properties for qPCR applications. BMC Biotechnol 2007; 7:76-92.
23. Wang W, Chen K, Xu C. DNA quantification using EvaGreen and a real-time PCR instrument. Anal Biochem 2006; 356:303-305.
24. Sang F, Ren J. Capillary electrophoresis of double-stranded DNA fragments using a new fluorescence intercalating dye EvaGreen. J Sep Sci 2006; 29:1275-1280.
25. Lifshitz J, McIntosh T. Age-associated mitochondrial DNA deletions are not evident chronically after experimental brain injury in the rat. J Neurotrauma, 2003, 201, 39K-49K [Pub Med: 12675968]
26. Richter C. Oxidative damage to mitochondrial DNA and its relationship to ageing. Int J Biochem Cell Bio 1995; l27:647-653.
27. Atilano SR, Coskun P, Chwa M. Accumulation of mitochondrial DNA damage in keratoconus corneas. Invest Ophthalmol Vis Sci 2005; 46:1256-1263.
28. McNulty R, Wang H, Mathias R. Regulation of tissue oxygen levels in the mammalian lens. J Physiol 2004; 559:883-898.
29. Pendergrass W, Penn P, Possin D. Accumulation of DNA, nuclear and mitochondrial debris, and ROS at sites of agerelated cortical cataract in mice. Invest Ophthalmol Vis Sci 2005; 46:4661-4670.
30. Jarrett SG, Lin H, Godley BF. Mitochondrial DNA damage and its potential role in retinal degeneration. Prog Retin Eye Res 2008; 27:596-607.
31. Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation,anddisease. FASEB J 2003; 17:1195-1214.
32. Nishikawa T, Sasahara T, Kiritoshi S. Evaluation of urinary 8-hydro-xydeoxyguanosine as a novel biomarker of macrovascular complications in type 2 diabetes. Diabetes Care 2003; 26:1507-1512.
33. Ku YP, Jin M, Kim KH. Immunolocalization of 8-OHdG and OGG1 in pancreatic islets of streptozotocin-induced diabetic rats. Acta histochem 2009; 11:138-144.
34. LeDoux SP, Druzhyna NM, Hollensworth SB. Mitochondrial DNA repair: a critical player in the response of cells of the CNS to genotoxic insults. Neuroscience 2007; 145:1249-1259.
35. Nicolai Balle Larsen. Merete Rasmussen, Lene Juel Rasmussen. Nuclear and mitochondrial DNA repair: similar pathways? Mitochondrion 2005; 5:89-108.
36. Dodson ML, Lloyd RS. Mechanistic comparisons among base excision repair glycolsylases. Free Radic Biol Med 2002; 32:678-682.
37. Vidal AE, Hickson ID, Boiteux S. Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity step. Nucleic Acids Res 2001; 29:1285-1292.
38. Tomkinson AE, Mackey ZB. Structure and function of mammalian DNA ligases. Mutat Res 1998; 407:1-9.
39. Silva JP, Gomes AC, Coutinho OP. Oxidative DNA damage protection and repair by polyphenolic compounds in PC12 cells. Eur J Pharmacol 2008; 601:50-60.
40. Yakes FM, Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 1997; 94:514-519.
41. Larsen NB, Rasmussen M, Rasmussen LJ. Nuclear and mitochondrial DNA repair: similar pathways? Mitochondrion 2005; 5:89-108.
42. Tang Y, Schon EA, Wilichowski E, Vazquez-Memije ME, Davidson E, King MP. Rearrangements of human mitochondrial DNA (mtDNA): new insights into the regulation of mtDNA copy number and gene expression. Mol Biol Cell 2000; 11:1471-1485.
43. Wei YH, Lee CF, Lee HC, Ma YS, Wang CW, Lu CY, Pang CY. Increases of mitochondrialmass and mitochondrial genome in association with enhanced oxidative stress in human cells harboring 4,977 BP-deleted mitochondrial DNA. Ann N Y Acad Sci 2001; 928:97-112.
44. Van Houten B, Woshner V, Santos JH. Role of mitochondrial DNA in toxic responses to oxidative stress. DNA Repair (Amst) 2006; 5:145-152.
45. Kowluru RA, Kowluru V, Xiong Y. Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress. Free Radic Biol Med 2006; 41:1191-1196.
46. Wei YH, Lee CF, Lee HC. Increases of mitochondrial mass and mitochondrial genome in association with enhanced oxidative stress in human cells harboring 4977 bp-deleted mitochondrial DNA. Ann N Y Acad Sci 2001; 28:97-112.
47. Santos JH, Hunakova L, Chen Y. Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death. J Biol Chem 2003; 278:1728-1734.
48. Pendergrass WR, Penn PE, Possin DE. Cellular debris and ROS in age-related cortical cataract are caused by inappropriate involution of the surface epithelial cells into the lens cortex. Mol Vis 2006; 12:712-724.
49. Truscott RJW. Age-related nuclear cataract-oxidation is the key. Exp Eye Res 2005; 80:709-725.
50. Green K. Free radicals and aging of anterior segment tissues of the eye: a hypothesis. Ophthalmic Res 1995; 27:l43-149.
51. Carper DA, Sun JK, Iwata TJ. Oxidative stress induces differential gene expression in a human lens epithelial cell line. Invest Ophthalmol Vis Sci 1999; 40:400-406.