-
1
-
-
77953995002
-
Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers
-
Chi P, Allis CD, Wang GG. Covalent histone modifications-- miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer. 2010;10:457-469.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 457-469
-
-
Chi, P.1
Allis, C.D.2
Wang, G.G.3
-
2
-
-
79551562850
-
Chromatin dynamics during repair of chromosomal DNA double-strand breaks
-
Sinha M, Peterson CL. Chromatin dynamics during repair of chromosomal DNA double-strand breaks. Epigenomics. 2009;1:371-385.
-
(2009)
Epigenomics
, vol.1
, pp. 371-385
-
-
Sinha, M.1
Peterson, C.L.2
-
3
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem. 1998;273:5858-5868.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
4
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A. Genomic instability in mice lacking histone H2AX. Science. 2002;296:922-927.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
Reina-San-Martin, B.7
Coppola, V.8
Meffre, E.9
Difilippantonio, M.J.10
Redon, C.11
Pilch, D.R.12
Olaru, A.13
Eckhaus, M.14
Camerini-Otero, R.D.15
Tessarollo, L.16
Livak, F.17
Manova, K.18
Bonner, W.M.19
Nussenzweig, M.C.20
Nussenzweig, A.21
more..
-
5
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
-
Polo SE, Jackson SP. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev. 2011;25:409-433.
-
(2011)
Genes Dev
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
6
-
-
80052146061
-
Chromatin and the DNA damage response: The cancer connection
-
Luijsterburg MS, van Attikum H. Chromatin and the DNA damage response: The cancer connection. Mol Oncol. 2011;5:349-367.
-
(2011)
Mol Oncol
, vol.5
, pp. 349-367
-
-
Luijsterburg, M.S.1
van Attikum, H.2
-
7
-
-
44449136965
-
HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response
-
Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR. HP1- beta mobilization promotes chromatin changes that initiate the DNA damage response. Nature. 2008;453:682-686.
-
(2008)
Nature
, vol.453
, pp. 682-686
-
-
Ayoub, N.1
Jeyasekharan, A.D.2
Bernal, J.A.3
Venkitaraman, A.R.4
-
8
-
-
70449518412
-
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60
-
Sun Y, Jiang X, Xu Y, Ayrapetov MK, Moreau LA, Whetstine JR, Price BD. Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. Nat Cell Biol. 2009;11:1376-1382.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1376-1382
-
-
Sun, Y.1
Jiang, X.2
Xu, Y.3
Ayrapetov, M.K.4
Moreau, L.A.5
Whetstine, J.R.6
Price, B.D.7
-
9
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen Y, Zgheib O, Ditullio RA Jr, Gorgoulis VG, Zacharatos P, Petty TJ, Sheston EA, Mellert HS, Stavridi ES, Halazonetis TD. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature. 2004;432:406-411.
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio Jr., R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Mellert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
10
-
-
79551665780
-
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
-
Pei H, Zhang L, Luo K, Qin Y, Chesi M, Fei F, Bergsagel PL, Wang L, You Z, Lou Z. MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature. 2011;470:124-128.
-
(2011)
Nature
, vol.470
, pp. 124-128
-
-
Pei, H.1
Zhang, L.2
Luo, K.3
Qin, Y.4
Chesi, M.5
Fei, F.6
Bergsagel, P.L.7
Wang, L.8
You, Z.9
Lou, Z.10
-
11
-
-
35148894396
-
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics
-
I kura T, Tashiro S, Kakino A, Shima H, Jacob N, Amunugama R, Yoder K, Izumi S, Kuraoka I, Tanaka K, Kimura H, Ikura M, Nishikubo S, Ito T, Muto A, Miyagawa K, Takeda S, Fishel R, Igarashi K, Kamiya K. DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol. 2007;27:7028-7040.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7028-7040
-
-
Ikura, T.1
Tashiro, S.2
Kakino, A.3
Shima, H.4
Jacob, N.5
Amunugama, R.6
Yoder, K.7
Izumi, S.8
Kuraoka, I.9
Tanaka, K.10
Kimura, H.11
Ikura, M.12
Nishikubo, S.13
Ito, T.14
Muto, A.15
Miyagawa, K.16
Takeda, S.17
Fishel, R.18
Igarashi, K.19
Kamiya, K.20
more..
-
12
-
-
30344444484
-
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
-
Murr R, Loizou JI, Yang YG, Cuenin C, Li H, Wang ZQ, Herceg Z. Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nat Cell Biol. 2006;8:91-99.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 91-99
-
-
Murr, R.1
Loizou, J.I.2
Yang, Y.G.3
Cuenin, C.4
Li, H.5
Wang, Z.Q.6
Herceg, Z.7
-
13
-
-
58149328408
-
Activation of ATM depends on chromatin interactions occurring before induction of DNA damage
-
Kim YC, Gerlitz G, Furusawa T, Catez F, Nussenzweig A, Oh KS, Kraemer KH, Shiloh Y, Bustin M. Activation of ATM depends on chromatin interactions occurring before induction of DNA damage. Nat Cell Biol. 2009;11:92-96.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 92-96
-
-
Kim, Y.C.1
Gerlitz, G.2
Furusawa, T.3
Catez, F.4
Nussenzweig, A.5
Oh, K.S.6
Kraemer, K.H.7
Shiloh, Y.8
Bustin, M.9
-
14
-
-
34548544648
-
Chromatin remodeling and cancer, Part II: ATP-dependent chromatin remodeling
-
Wang GG, Allis CD, Chi P. Chromatin remodeling and cancer, Part II: ATP-dependent chromatin remodeling. Trends Mol Med. 2007;13:373-380.
-
(2007)
Trends Mol Med
, vol.13
, pp. 373-380
-
-
Wang, G.G.1
Allis, C.D.2
Chi, P.3
-
15
-
-
10944233962
-
Recruitment of the INO80 complex by H2A phosphorylation links ATPdependent chromatin remodeling with DNA double-strand break repair
-
van Attikum H, Fritsch O, Hohn B, Gasser SM. Recruitment of the INO80 complex by H2A phosphorylation links ATPdependent chromatin remodeling with DNA double-strand break repair. Cell. 2004;119:777-788.
-
(2004)
Cell
, vol.119
, pp. 777-788
-
-
van Attikum, H.1
Fritsch, O.2
Hohn, B.3
Gasser, S.M.4
-
16
-
-
10944267160
-
Binding of chromatinmodifying activities to phosphorylated histone H2A at DNA damage sites
-
Downs JA, Allard S, Jobin-Robitaille O, Javaheri A, Auger A, Bouchard N, Kron SJ, Jackson SP, Côté J. Binding of chromatinmodifying activities to phosphorylated histone H2A at DNA damage sites. Mol Cell. 2004;16:979-990.
-
(2004)
Mol Cell
, vol.16
, pp. 979-990
-
-
Downs, J.A.1
Allard, S.2
Jobin-Robitaille, O.3
Javaheri, A.4
Auger, A.5
Bouchard, N.6
Kron, S.J.7
Jackson, S.P.8
Côté, J.9
-
17
-
-
77951498720
-
A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair
-
Lee HS, Park JH, Kim SJ, Kwon SJ, Kwon J. A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair. EMBO J. 2010;29:1434-1445.
-
(2010)
EMBO J
, vol.29
, pp. 1434-1445
-
-
Lee, H.S.1
Park, J.H.2
Kim, S.J.3
Kwon, S.J.4
Kwon, J.5
-
18
-
-
67650034511
-
BRIT1/MCPH1 links chromatin remodelling to DNA damage response
-
Peng G, Yim EK, Dai H, Jackson AP, Burgt I, Pan MR, Hu R, Li K, Lin SY. BRIT1/MCPH1 links chromatin remodelling to DNA damage response. Nat Cell Biol. 2009;11:865-872.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 865-872
-
-
Peng, G.1
Yim, E.K.2
Dai, H.3
Jackson, A.P.4
Burgt, I.5
Pan, M.R.6
Hu, R.7
Li, K.8
Lin, S.Y.9
-
19
-
-
78650536985
-
Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites
-
Erdel F, Schubert T, Marth C, Längst G, Rippe K. Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites. Proc Natl Acad Sci U S A. 2010;107:19873-19878.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 19873-19878
-
-
Erdel, F.1
Schubert, T.2
Marth, C.3
Längst, G.4
Rippe, K.5
-
20
-
-
79951971464
-
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination
-
Nakamura K, Kato A, Kobayashi J, Yanagihara H, Sakamoto S, Oliveira DV, Shimada M, Tauchi H, Suzuki H, Tashiro S, Zou L, Komatsu K. Regulation of homologous recombination by RNF20- dependent H2B ubiquitination. Mol Cell. 2011;41:515-528.
-
(2011)
Mol Cell
, vol.41
, pp. 515-528
-
-
Nakamura, K.1
Kato, A.2
Kobayashi, J.3
Yanagihara, H.4
Sakamoto, S.5
Oliveira, D.V.6
Shimada, M.7
Tauchi, H.8
Suzuki, H.9
Tashiro, S.10
Zou, L.11
Komatsu, K.12
-
21
-
-
36849066365
-
A YY1-INO80 complex regulates genomic stability through homologous recombinationbased repair
-
Wu S, Shi Y, Mulligan P, Gay F, Landry J, Liu H, Lu J, Qi HH, Wang W, Nickoloff JA, Wu C, Shi Y. A YY1-INO80 complex regulates genomic stability through homologous recombinationbased repair. Nat Struct Mol Biol. 2007;14:1165-1172.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 1165-1172
-
-
Wu, S.1
Shi, Y.2
Mulligan, P.3
Gay, F.4
Landry, J.5
Liu, H.6
Lu, J.7
Qi, H.H.8
Wang, W.9
Nickoloff, J.A.10
Wu, C.11
Shi, Y.12
-
22
-
-
69549083315
-
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler
-
Gottschalk AJ, Timinszky G, Kong SE, Jin J, Cai Y, Swanson SK, Washburn MP, Florens L, Ladurner AG, Conaway JW, Conaway RC. Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler. Proc Natl Acad Sci U S A. 2009;106:13770-13774.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13770-13774
-
-
Gottschalk, A.J.1
Timinszky, G.2
Kong, S.E.3
Jin, J.4
Cai, Y.5
Swanson, S.K.6
Washburn, M.P.7
Florens, L.8
Ladurner, A.G.9
Conaway, J.W.10
Conaway, R.C.11
-
23
-
-
61349151633
-
Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis
-
Nagarajan P, Onami TM, Rajagopalan S, Kania S, Donnell R, Venkatachalam S. Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis. Oncogene. 2009;28:1053-1062.
-
(2009)
Oncogene
, vol.28
, pp. 1053-1062
-
-
Nagarajan, P.1
Onami, T.M.2
Rajagopalan, S.3
Kania, S.4
Donnell, R.5
Venkatachalam, S.6
-
24
-
-
77956379478
-
The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage
-
Larsen DH, Poinsignon C, Gudjonsson T, Dinant C, Payne MR, Hari FJ, Danielsen JM, Menard P, Sand JC, Stucki M, Lukas C, Bartek J, Andersen JS, Lukas J. The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage. J Cell Biol. 2010;190:731-740.
-
(2010)
J Cell Biol
, vol.190
, pp. 731-740
-
-
Larsen, D.H.1
Poinsignon, C.2
Gudjonsson, T.3
Dinant, C.4
Payne, M.R.5
Hari, F.J.6
Danielsen, J.M.7
Menard, P.8
Sand, J.C.9
Stucki, M.10
Lukas, C.11
Bartek, J.12
Andersen, J.S.13
Lukas, J.14
-
25
-
-
77956387556
-
The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage
-
Smeenk G, Wiegant WW, Vrolijk H, Solari AP, Pastink A, van Attikum H. The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage. J Cell Biol. 2010;190:741- 749.
-
(2010)
J Cell Biol
, vol.190
, pp. 741-749
-
-
Smeenk, G.1
Wiegant, W.W.2
Vrolijk, H.3
Solari, A.P.4
Pastink, A.5
van Attikum, H.6
-
26
-
-
70349645266
-
Ageing-related chromatin defects through loss of the NURD complex
-
Pegoraro G, Kubben N, Wickert U, Göhler H, Hoffmann K, Misteli T. Ageing-related chromatin defects through loss of the NURD complex. Nat Cell Biol. 2009;11:1261-1267.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1261-1267
-
-
Pegoraro, G.1
Kubben, N.2
Wickert, U.3
Göhler, H.4
Hoffmann, K.5
Misteli, T.6
-
27
-
-
47349107760
-
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
-
Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, Löbrich M, Jeggo PA. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell. 2008;31:167- 177.
-
(2008)
Mol Cell
, vol.31
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Löbrich, M.6
Jeggo, P.A.7
-
28
-
-
78549254849
-
The 53BP1-EXPAND1 connection in chromatin structure regulation
-
Sy SM, Chen J, Huen MS. The 53BP1-EXPAND1 connection in chromatin structure regulation. Nucleus. 2010;1:472-474.
-
(2010)
Nucleus
, vol.1
, pp. 472-474
-
-
Sy, S.M.1
Chen, J.2
Huen, M.S.3
-
29
-
-
1642602686
-
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks
-
Sedelnikova OA, Horikawa I, Zimonjic DB, Popescu NC, Bonner WM, Barrett JC. Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks. Nat Cell Biol. 2004;6:168-170.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 168-170
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Zimonjic, D.B.3
Popescu, N.C.4
Bonner, W.M.5
Barrett, J.C.6
-
30
-
-
33644692330
-
Cellular senescence in aging primates
-
Herbig U, Ferreira M, Condel L, Carey D, Sedivy JM. Cellular senescence in aging primates. Science. 2006;311:1257.
-
(2006)
Science
, vol.311
, pp. 1257
-
-
Herbig, U.1
Ferreira, M.2
Condel, L.3
Carey, D.4
Sedivy, J.M.5
-
33
-
-
4544377929
-
Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity
-
Hasty P, Vijg J Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity. Aging Cell. 2004;3:55-65.
-
(2004)
Aging Cell
, vol.3
, pp. 55-65
-
-
Hasty, P.1
Vijg, J.2
-
34
-
-
22544466685
-
Genomic instability in laminopathy-based premature aging
-
Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X, Huang JD, Li KM, Chau PY, Chen DJ, Pei D, Pendas AM, Cadiñanos J, López-Otín C, Tse HF, Hutchison C, Chen J, Cao Y, Cheah KS, Tryggvason K, Zhou Z. Genomic instability in laminopathy-based premature aging. Nat Med. 2005;11:780-785.
-
(2005)
Nat Med
, vol.11
, pp. 780-785
-
-
Liu, B.1
Wang, J.2
Chan, K.M.3
Tjia, W.M.4
Deng, W.5
Guan, X.6
Huang, J.D.7
Li, K.M.8
Chau, P.Y.9
Chen, D.J.10
Pei, D.11
Pendas, A.M.12
Cadiñanos, J.13
López-Otín, C.14
Tse, H.F.15
Hutchison, C.16
Chen, J.17
Cao, Y.18
Cheah, K.S.19
Tryggvason, K.20
Zhou, Z.21
more..
-
35
-
-
0037673950
-
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
-
Eriksson Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Recurrent de novo point mutations in lamin A cause Hutchinson- Gilford progeria syndrome. Nature. 2003;423:293-298.
-
(2003)
Nature
, vol.423
, pp. 293-298
-
-
Eriksson Brown, W.T.1
Gordon, L.B.2
Glynn, M.W.3
Singer, J.4
Scott, L.5
Erdos, M.R.6
Robbins, C.M.7
Moses, T.Y.8
Berglund, P.9
Dutra, A.10
Pak, E.11
Durkin, S.12
Csoka, A.B.13
Boehnke, M.14
Glover, T.W.15
Collins, F.S.16
-
36
-
-
0036578920
-
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice
-
Pendás AM, Zhou Z, Cadiñanos J, Freije JM, Wang J, Hultenby K, Astudillo A, Wernerson A, Rodríguez F, Tryggvason K, López- Otín C. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet. 2002;31:94-99.
-
(2002)
Nat Genet
, vol.31
, pp. 94-99
-
-
Pendás, A.M.1
Zhou, Z.2
Cadiñanos, J.3
Freije, J.M.4
Wang, J.5
Hultenby, K.6
Astudillo, A.7
Wernerson, A.8
Rodríguez, F.9
Tryggvason, K.10
López-Otín, C.11
-
37
-
-
33745904741
-
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome
-
Dahl KN, Scaffidi P, Islam MF, Yodh AG, Wilson KL, Misteli TKN. Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2006;103:10271-10276.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10271-10276
-
-
Dahl, K.N.1
Scaffidi, P.2
Islam, M.F.3
Yodh, A.G.4
Wilson, K.L.5
Misteli, T.K.N.6
-
38
-
-
33745016642
-
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
-
Shumaker DK, Dechat T, Kohlmaier A, Adam SA, Bozovsky MR, Erdos MR, Eriksson M, Goldman AE, Khuon S, Collins FS, Jenuwein T, Goldman RD. Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc Natl Acad Sci U S A. 2006;103:8703-8708.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 8703-8708
-
-
Shumaker, D.K.1
Dechat, T.2
Kohlmaier, A.3
Adam, S.A.4
Bozovsky, M.R.5
Erdos, M.R.6
Eriksson, M.7
Goldman, A.E.8
Khuon, S.9
Collins, F.S.10
Jenuwein, T.11
Goldman, R.D.12
-
39
-
-
2942643923
-
Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome
-
Goldman RD, Shumaker DK, Erdos MR, Eriksson M, Goldman AE, Gordon LB, Gruenbaum Y, Khuon S, Mendez M, Varga R, Collins FS. Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2004;101:8963-8968.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8963-8968
-
-
Goldman, R.D.1
Shumaker, D.K.2
Erdos, M.R.3
Eriksson, M.4
Goldman, A.E.5
Gordon, L.B.6
Gruenbaum, Y.7
Khuon, S.8
Mendez, M.9
Varga, R.10
Collins, F.S.11
-
40
-
-
19944428509
-
Heterozygosity for Lmna deficiency eliminates the progerialike phenotypes in Zmpste24-deficient mice
-
Fong LG, Ng JK, Meta M, Coté N, Yang SH, Stewart CL, Sullivan T, Burghardt A, Majumdar S, Reue K, Bergo MO, Young SG. Heterozygosity for Lmna deficiency eliminates the progerialike phenotypes in Zmpste24-deficient mice. Proc Natl Acad Sci U S A. 2004;101:18111-18116.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 18111-18116
-
-
Fong, L.G.1
Ng, J.K.2
Meta, M.3
Coté, N.4
Yang, S.H.5
Stewart, C.L.6
Sullivan, T.7
Burghardt, A.8
Majumdar, S.9
Reue, K.10
Bergo, M.O.11
Young, S.G.12
-
41
-
-
33845699084
-
DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A
-
Liu Y, Rusinol A, Sinensky M, Wang Y, Zou Y. DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A. J Cell Sci. 2006;119:4644-4649.
-
(2006)
J Cell Sci
, vol.119
, pp. 4644-4649
-
-
Liu, Y.1
Rusinol, A.2
Sinensky, M.3
Wang, Y.4
Zou, Y.5
-
42
-
-
33746883839
-
K Expression of diseasecausing lamin A mutants impairs the formation of DNA repair foci
-
Manju K, Muralikrishna B, Parnaik V K Expression of diseasecausing lamin A mutants impairs the formation of DNA repair foci. J Cell Sci. 2006;119:2704-2714.
-
(2006)
J Cell Sci
, vol.119
, pp. 2704-2714
-
-
Manju, K.1
Muralikrishna, B.2
Parnaik, V.3
-
43
-
-
77956875652
-
Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford Progeria Syndrome fibroblasts
-
Constantinescu D, Csoka AB, Navara CS, Schatten GP. Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson- Gilford Progeria Syndrome fibroblasts. Exp Cell Res. 2010;316:2747-2759.
-
(2010)
Exp Cell Res
, vol.316
, pp. 2747-2759
-
-
Constantinescu, D.1
Csoka, A.B.2
Navara, C.S.3
Schatten, G.P.4
-
44
-
-
42149158389
-
Lamin A/C, laminopathies and premature ageing
-
Liu B, Zhou Z. Lamin A/C, laminopathies and premature ageing. Histol Histopathol. 2008;23:747-763.
-
(2008)
Histol Histopathol
, vol.23
, pp. 747-763
-
-
Liu, B.1
Zhou, Z.2
-
45
-
-
69949144385
-
Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A
-
Musich PR, Zou Y. Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A. Aging (Albany NY). 2009;1:28-37.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 28-37
-
-
Musich, P.R.1
Zou, Y.2
-
47
-
-
41649097238
-
Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
-
Dechat T, Pfleghaar K, Sengupta K, Shimi T, Shumaker DK, Solimando L, Goldman RD. Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. Genes Dev. 2008;22:832-853.
-
(2008)
Genes Dev
, vol.22
, pp. 832-853
-
-
Dechat, T.1
Pfleghaar, K.2
Sengupta, K.3
Shimi, T.4
Shumaker, D.K.5
Solimando, L.6
Goldman, R.D.7
-
48
-
-
73949123695
-
The role of nuclear organization in cancer
-
Lever E, Sheer D. The role of nuclear organization in cancer. The Journal of Pathology. 2010;220:114-125.
-
(2010)
The Journal of Pathology
, vol.220
, pp. 114-125
-
-
Lever, E.1
Sheer, D.2
-
49
-
-
79961083402
-
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice
-
Krishnan V, Chow MZ, Wang Z, Zhang L, Liu B, Liu X, Zhou Z. Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24- deficient mice. Proc Natl Acad Sci U S A. 2011;108:12325-12330.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 12325-12330
-
-
Krishnan, V.1
Chow, M.Z.2
Wang, Z.3
Zhang, L.4
Liu, B.5
Liu, X.6
Zhou, Z.7
-
50
-
-
32444434989
-
Histone H4-K16 acetylation controls chromatin structure and protein interactions
-
Shogren-Knaak M, Ishii H, Sun JM, Pazin MJ, Davie JR, Peterson CL. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science. 2006;311:844-847.
-
(2006)
Science
, vol.311
, pp. 844-847
-
-
Shogren-Knaak, M.1
Ishii, H.2
Sun, J.M.3
Pazin, M.J.4
Davie, J.R.5
Peterson, C.L.6
-
51
-
-
78649533191
-
MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1
-
Li X, Corsa CA, Pan PW, Wu L, Ferguson D, Yu X, Min J, Dou Y. MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. Mol Cell Biol. 2010;30:5335-5347.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 5335-5347
-
-
Li, X.1
Corsa, C.A.2
Pan, P.W.3
Wu, L.4
Ferguson, D.5
Yu, X.6
Min, J.7
Dou, Y.8
-
52
-
-
77954360144
-
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair
-
Sharma GG, So S, Gupta A, Kumar R, Cayrou C, Avvakumov N, Bhadra U, Pandita RK, Porteus MH, Chen DJ, Cote J, Pandita TK. MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol Cell Biol. 2010;30:3582-3595.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3582-3595
-
-
Sharma, G.G.1
So, S.2
Gupta, A.3
Kumar, R.4
Cayrou, C.5
Avvakumov, N.6
Bhadra, U.7
Pandita, R.K.8
Porteus, M.H.9
Chen, D.J.10
Cote, J.11
Pandita, T.K.12
-
53
-
-
79952743720
-
Purkinje cellspecific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice
-
Kumar R, Hunt CR, Gupta A, Nannepaga S, Pandita RK, Shay JW, Bachoo R, Ludwig T, Burns DK, Pandita TK. Purkinje cellspecific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice. Proc Natl Acad Sci U S A. 2011;108:3636-3641.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3636-3641
-
-
Kumar, R.1
Hunt, C.R.2
Gupta, A.3
Nannepaga, S.4
Pandita, R.K.5
Shay, J.W.6
Bachoo, R.7
Ludwig, T.8
Burns, D.K.9
Pandita, T.K.10
-
55
-
-
79952268809
-
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer
-
Di Micco R, Sulli G, Dobreva M, Liontos M, Botrugno OA, Gargiulo G, dal Zuffo R, Matti V, d'Ario G, Montani E, Mercurio C, Hahn WC, Gorgoulis V, Minucci S, d'Adda di Fagagna F. Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer. Nat Cell Biol. 2011;13:292-302.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 292-302
-
-
Di Micco, R.1
Sulli, G.2
Dobreva, M.3
Liontos, M.4
Botrugno, O.A.5
Gargiulo, G.6
dal Zuffo, R.7
Matti, V.8
d'Ario, G.9
Montani, E.10
Mercurio, C.11
Hahn, W.C.12
Gorgoulis, V.13
Minucci, S.14
d'Adda di Fagagna, F.15
-
56
-
-
34248523169
-
Recovery of learning and memory is associated with chromatin remodeling
-
Fischer A, Sananbenesi F. Wang, X, Dobbin, M, Tsai, LH. Recovery of learning and memory is associated with chromatin remodeling. Nature. 2007;447:178-182.
-
(2007)
Nature
, vol.447
, pp. 178-182
-
-
Fischer, A.1
Sananbenesi, F.2
Wang, X.3
Dobbin, M.4
Tsai, L.H.5
-
57
-
-
80855148401
-
Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA
-
Ying M, Xu R, Wu X, Zhu H, Zhuang Y, Han M, Xu T. Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA. J Biol Chem. 2007;447:178-182.
-
(2007)
J Biol Chem
, vol.447
, pp. 178-182
-
-
Ying, M.1
Xu, R.2
Wu, X.3
Zhu, H.4
Zhuang, Y.5
Han, M.6
Xu, T.7
-
58
-
-
67649310030
-
Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease
-
Francis YI, Fà M, Ashraf H, Zhang H, Staniszewski A, Latchman DS, Arancio O. Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease. Alzheimers Dis. 2009;18:131-139.
-
(2009)
Alzheimers Dis
, vol.18
, pp. 131-139
-
-
Francis, Y.I.1
Fà, M.2
Ashraf, H.3
Zhang, H.4
Staniszewski, A.5
Latchman, D.S.6
Arancio, O.7
-
59
-
-
33749353184
-
Histone deacetylase-1 mediated histone modification regulates osteogenic differentiation
-
Lee HW, Suh JH, Kim AY, Lee YS, Park SY, Kim JB. Histone deacetylase-1 mediated histone modification regulates osteogenic differentiation. Mol Endocrinology. 2009;20:202432- 202443.
-
(2009)
Mol Endocrinology
, vol.20
, pp. 202432-202443
-
-
Lee, H.W.1
Suh, J.H.2
Kim, A.Y.3
Lee, Y.S.4
Park, S.Y.5
Kim, J.B.6
-
60
-
-
72949109772
-
Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling
-
Zhang M, Poplawski M, Yen K, Cheng H, Bloss E, Zhu X, Patel H, Mobbs CV. Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling. PLoS Biology. 2009;7:e1000245.
-
(2009)
PLoS Biology
, vol.7
-
-
Zhang, M.1
Poplawski, M.2
Yen, K.3
Cheng, H.4
Bloss, E.5
Zhu, X.6
Patel, H.7
Mobbs, C.V.8
-
61
-
-
33646745137
-
Lamin A-dependent nuclear defects in human aging
-
Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human aging. Science. 2006;312:1059-1063.
-
(2006)
Science
, vol.312
, pp. 1059-1063
-
-
Scaffidi, P.1
Misteli, T.2
-
62
-
-
41649101975
-
The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin
-
McClintock D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K. The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin. PLoS One. 2007;2:e1269.
-
(2007)
PLoS One
, vol.2
-
-
McClintock, D.1
Ratner, D.2
Lokuge, M.3
Owens, D.M.4
Gordon, L.B.5
Collins, F.S.6
Djabali, K.7
-
63
-
-
77953023624
-
Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging
-
Ragnauth CD, Warren DT, Liu Y, McNair R, Tajsic T, Figg N, Shroff R, Skepper J, Shanahan CM. Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging. Circulation. 2010;121:2200-2210.
-
(2010)
Circulation
, vol.121
, pp. 2200-2210
-
-
Ragnauth, C.D.1
Warren, D.T.2
Liu, Y.3
McNair, R.4
Tajsic, T.5
Figg, N.6
Shroff, R.7
Skepper, J.8
Shanahan, C.M.9
-
64
-
-
79959928025
-
Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
-
Cao K, Blair CD, Faddah DA, Kieckhaefer JE, Olive M, Erdos MR, Nabel EG, Collins FS. Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts. J Clin Invest. 2011;121(7):2833-2844.
-
(2011)
J Clin Invest
, vol.121
, Issue.7
, pp. 2833-2844
-
-
Cao, K.1
Blair, C.D.2
Faddah, D.A.3
Kieckhaefer, J.E.4
Olive, M.5
Erdos, M.R.6
Nabel, E.G.7
Collins, F.S.8
-
65
-
-
38349134829
-
Delayed kinetics of DNA doublestrand break processing in normal and pathological aging
-
Sedelnikova OA, Horikawa I, Redon C, Nakamura A, Zimonjic DB, Popescu NC, Bonner WM. Delayed kinetics of DNA doublestrand break processing in normal and pathological aging. Aging Cell. 2008;7: 89-100.
-
(2008)
Aging Cell
, vol.7
, pp. 89-100
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Redon, C.3
Nakamura, A.4
Zimonjic, D.B.5
Popescu, N.C.6
Bonner, W.M.7
-
66
-
-
37549014206
-
The Mammalian Ortholog of Drosophila MOF That Acetylates Histone H4 Lysine 16 Is Essential for Embryogenesis and Oncogenesis
-
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK. The Mammalian Ortholog of Drosophila MOF That Acetylates Histone H4 Lysine 16 Is Essential for Embryogenesis and Oncogenesis. Mol Cell Biol. 2008;28:397-409.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 397-409
-
-
Gupta, A.1
Guerin-Peyrou, T.G.2
Sharma, G.G.3
Park, C.4
Agarwal, M.5
Ganju, R.K.6
Pandita, S.7
Choi, K.8
Sukumar, S.9
Pandita, R.K.10
Ludwig, T.11
Pandita, T.K.12
-
67
-
-
73949160163
-
Aging alters histone H4 acetylation and, CDC2A., in mouse germinal vesicle stage, oocytes., Manosalva, I., González, A
-
Aging alters histone H4 acetylation and CDC2A in mouse germinal vesicle stage oocytes. Manosalva I, González A. Biol Reprod. 2009;81:1164-1171.
-
(2009)
Biol, Reprod
, vol.81
, pp. 1164-1171
-
-
-
68
-
-
67149099680
-
Histone H4 lysine 16 acetylation regulates cellular life span
-
Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. Histone H4 lysine 16 acetylation regulates cellular life span. Nature. 2009;459:802-807.
-
(2009)
Nature
, vol.459
, pp. 802-807
-
-
Dang, W.1
Steffen, K.K.2
Perry, R.3
Dorsey, J.A.4
Johnson, F.B.5
Shilatifard, A.6
Kaeberlein, M.7
Kennedy, B.K.8
Berger, S.L.9
-
69
-
-
27244435939
-
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
-
Chua KF, Mostoslavsky R, Lombard DB, Pang WW, Saito S, Franco S, Kaushal D, Cheng HL, Fischer MR, Stokes N, Murphy MM, Appella E, Alt FW. Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. Cell Metab. 2005;2:67-76.
-
(2005)
Cell Metab
, vol.2
, pp. 67-76
-
-
Chua, K.F.1
Mostoslavsky, R.2
Lombard, D.B.3
Pang, W.W.4
Saito, S.5
Franco, S.6
Kaushal, D.7
Cheng, H.L.8
Fischer, M.R.9
Stokes, N.10
Murphy, M.M.11
Appella, E.12
Alt, F.W.13
-
70
-
-
77953257025
-
Aging and disease: connections to sirtuins
-
Donmez G, Guarente L. Aging and disease: connections to sirtuins. Aging Cell. 2010;9:285-290.
-
(2010)
Aging Cell
, vol.9
, pp. 285-290
-
-
Donmez, G.1
Guarente, L.2
-
71
-
-
34249683635
-
Cross-talk between aging and cancer: the epigenetic language
-
Fraga MF, Agrelo R, Esteller M. Cross-talk between aging and cancer: the epigenetic language. Ann N Y Acad Sci. 2007;1100:60-74.
-
(2007)
Ann N Y Acad Sci
, vol.1100
, pp. 60-74
-
-
Fraga, M.F.1
Agrelo, R.2
Esteller, M.3
-
72
-
-
68149100569
-
The role of epigenetics in aging and age-related diseases
-
Calvanese V, Lara E, Kahn A, Fraga MF. The role of epigenetics in aging and age-related diseases. Ageing Res Rev. 2009;8:268-276.
-
(2009)
Ageing Res Rev
, vol.8
, pp. 268-276
-
-
Calvanese, V.1
Lara, E.2
Kahn, A.3
Fraga, M.F.4
-
73
-
-
77956520661
-
Elevated histone expression promotes life span extension
-
Feser J, Truong D, Das C, Carson JJ, Kieft J, Harkness T, Tyler JK. Elevated histone expression promotes life span extension. Mol Cell. 2010;39:724-735.
-
(2010)
Mol Cell
, vol.39
, pp. 724-735
-
-
Feser, J.1
Truong, D.2
Das, C.3
Carson, J.J.4
Kieft, J.5
Harkness, T.6
Tyler, J.K.7
-
74
-
-
79959836522
-
Chromatin structure as a mediator of aging
-
Feser J, Tyler J. Chromatin structure as a mediator of aging. FEBS Lett. 2011;585:2041-2048.
-
(2011)
FEBS Lett
, vol.585
, pp. 2041-2048
-
-
Feser, J.1
Tyler, J.2
-
75
-
-
77954660029
-
Members of the H3K4 trimethylation complex regulate lifespan in a germlinedependent manner in C. elegans
-
Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, Brunet A. Members of the H3K4 trimethylation complex regulate lifespan in a germlinedependent manner in C. elegans. Nature. 2010;466:383-387.
-
(2010)
Nature
, vol.466
, pp. 383-387
-
-
Greer, E.L.1
Maures, T.J.2
Hauswirth, A.G.3
Green, E.M.4
Leeman, D.S.5
Maro, G.S.6
Han, S.7
Banko, M.R.8
Gozani, O.9
Brunet, A.10
-
76
-
-
0015518651
-
Histone acetylation during aging of human cells in culture
-
Ryan JM, Cristofalo VJ. Histone acetylation during aging of human cells in culture. Biochem Biophys Res Commun. 1972;48:735-742.
-
(1972)
Biochem Biophys Res Commun
, vol.48
, pp. 735-742
-
-
Ryan, J.M.1
Cristofalo, V.J.2
-
77
-
-
0037131426
-
Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging
-
Sarg B, Koutzamani E, Helliger W, Rundquist I, Lindner HH. Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging. J Biol Chem. 2002;277:39195-39201.
-
(2002)
J Biol Chem
, vol.277
, pp. 39195-39201
-
-
Sarg, B.1
Koutzamani, E.2
Helliger, W.3
Rundquist, I.4
Lindner, H.H.5
-
78
-
-
77952168294
-
Altered histone acetylation is associated with agedependent memory impairment in mice
-
Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, Fischer A. Altered histone acetylation is associated with agedependent memory impairment in mice. Science. 2010;328:753- 756.
-
(2010)
Science
, vol.328
, pp. 753-756
-
-
Peleg, S.1
Sananbenesi, F.2
Zovoilis, A.3
Burkhardt, S.4
Bahari-Javan, S.5
Agis-Balboa, R.C.6
Cota, P.7
Wittnam, J.L.8
Gogol-Doering, A.9
Opitz, L.10
Salinas-Riester, G.11
Dettenhofer, M.12
Kang, H.13
Farinelli, L.14
Chen, W.15
Fischer, A.16
-
79
-
-
35848943273
-
Hematopoietic fingerprints: an expression database of stem cells and their progeny
-
Chambers SM, Boles NC, Lin KY, Tierney MP, Bowman TV, Bradfute SB, Chen AJ, Merchant AA, Sirin O, Weksberg DC, Merchant MG, Fisk CJ, Shaw CA, Goodell MA. Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell. 2007;1:578-591.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 578-591
-
-
Chambers, S.M.1
Boles, N.C.2
Lin, K.Y.3
Tierney, M.P.4
Bowman, T.V.5
Bradfute, S.B.6
Chen, A.J.7
Merchant, A.A.8
Sirin, O.9
Weksberg, D.C.10
Merchant, M.G.11
Fisk, C.J.12
Shaw, C.A.13
Goodell, M.A.14
-
80
-
-
77953190732
-
Emerging role of the MORF/MRG gene family in various biological processes, including aging
-
Chen M, Tominaga K, Pereira-Smith OM. Emerging role of the MORF/MRG gene family in various biological processes, including aging. Ann N Y Acad Sci. 2010;1197:134-141.
-
(2010)
Ann N Y Acad Sci
, vol.1197
, pp. 134-141
-
-
Chen, M.1
Tominaga, K.2
Pereira-Smith, O.M.3
-
81
-
-
66049150672
-
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
-
McCord RA, Michishita E, Hong T, Berber E, Boxer LD, Kusumoto R, Guan S, Shi X, Gozani O, Burlingame AL, Bohr VA, Chua KF. SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany NY). 2009;1:109-121.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 109-121
-
-
McCord, R.A.1
Michishita, E.2
Hong, T.3
Berber, E.4
Boxer, L.D.5
Kusumoto, R.6
Guan, S.7
Shi, X.8
Gozani, O.9
Burlingame, A.L.10
Bohr, V.A.11
Chua, K.F.12
-
82
-
-
79956086415
-
BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair
-
Ginjala V, Nacerddine K, Kulkarni A, Oza J, Hill SJ, Yao M, Citterio E, van Lohuizen M, Ganesan S. BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Mol Cell Biol. 2011;31:1972-1982.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1972-1982
-
-
Ginjala, V.1
Nacerddine, K.2
Kulkarni, A.3
Oza, J.4
Hill, S.J.5
Yao, M.6
Citterio, E.7
van Lohuizen, M.8
Ganesan, S.9
-
83
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell. 2008;135:907-918.
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
Wright, S.M.11
Mills, K.D.12
Bonni, A.13
Yankner, B.A.14
Scully, R.15
Prolla, T.A.16
Alt, F.W.17
Sinclair, D.A.18
-
84
-
-
84857117928
-
Histone exchange and histone modifications during transcription and aging
-
doi:10.1016/j.bbagrm.2011.08.001
-
Das C, Tyler JK. Histone exchange and histone modifications during transcription and aging. Biochim Biophys Acta. 2011 doi:10.1016/j.bbagrm.2011.08.001.
-
(2011)
Biochim Biophys Acta
-
-
Das, C.1
Tyler, J.K.2
-
85
-
-
77957354585
-
Methylated H3K4, a transcriptionassociated histone modification, is involved in the DNA damage response pathway
-
Faucher D, Wellinger RJ. Methylated H3K4, a transcriptionassociated histone modification, is involved in the DNA damage response pathway. PLoS Genet. 2010;6. pii: e1001082.
-
(2010)
PLoS Genet
, vol.6
-
-
Faucher, D.1
Wellinger, R.J.2
-
86
-
-
34848840031
-
Changes in histone acetylation during postovulatory aging of mouse oocyte
-
Huang JC, Yan LY, Lei ZL, Miao YL, Shi LH, Yang JW, Wang Q, Ouyang YC, Sun QY, Chen DY. Changes in histone acetylation during postovulatory aging of mouse oocyte. Biol Reprod. 2007;77:666-670.
-
(2007)
Biol Reprod
, vol.77
, pp. 666-670
-
-
Huang, J.C.1
Yan, L.Y.2
Lei, Z.L.3
Miao, Y.L.4
Shi, L.H.5
Yang, J.W.6
Wang, Q.7
Ouyang, Y.C.8
Sun, Q.Y.9
Chen, D.Y.10
-
87
-
-
77956553913
-
Haldar D. p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals
-
Vempati RK, Jayani RS, Notani D, Sengupta A, Galande S, Haldar D. p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals. J Biol Chem. 2010;285:28553-28564.
-
(2010)
J Biol Chem
, vol.285
, pp. 28553-28564
-
-
Vempati, R.K.1
Jayani, R.S.2
Notani, D.3
Sengupta, A.4
Galande, S.5
-
88
-
-
67650409769
-
Screen for DNA-damageresponsive histone modifications identifies H3K9Ac and H3K56Ac in human cells
-
Tjeertes JV, Miller KM, Jackson SP. Screen for DNA-damageresponsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. EMBO J. 2009;28:1878-1889.
-
(2009)
EMBO J
, vol.28
, pp. 1878-1889
-
-
Tjeertes, J.V.1
Miller, K.M.2
Jackson, S.P.3
-
89
-
-
66749102871
-
Histone H3-K56 acetylation is important for genomic stability in mammals
-
Yuan J, Pu M, Zhang Z, Lou Z. Histone H3-K56 acetylation is important for genomic stability in mammals. Cell Cycle. 2009;8:1747-1753.
-
(2009)
Cell Cycle
, vol.8
, pp. 1747-1753
-
-
Yuan, J.1
Pu, M.2
Zhang, Z.3
Lou, Z.4
-
90
-
-
77957814604
-
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
-
O'Sullivan RJ, Kubicek S, Schreiber SL, Karlseder J. Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres. Nat Struct Mol Biol. 2010;17:1218- 1225.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1218-1225
-
-
O'Sullivan, R.J.1
Kubicek, S.2
Schreiber, S.L.3
Karlseder, J.4
-
91
-
-
79955613209
-
Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors
-
Ogiwara H, Ui A, Otsuka A, Satoh H, Yokomi I, Nakajima S, Yasui A, Yokota J, Kohno T. Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene. 2011;30:2135-2146.
-
(2011)
Oncogene
, vol.30
, pp. 2135-2146
-
-
Ogiwara, H.1
Ui, A.2
Otsuka, A.3
Satoh, H.4
Yokomi, I.5
Nakajima, S.6
Yasui, A.7
Yokota, J.8
Kohno, T.9
-
92
-
-
58049213801
-
Chromatin reassembly signals the end of DNA repair
-
Chen CC, Tyler J. Chromatin reassembly signals the end of DNA repair. Cell Cycle. 2008;7:3792-3797.
-
(2008)
Cell Cycle
, vol.7
, pp. 3792-3797
-
-
Chen, C.C.1
Tyler, J.2
-
93
-
-
65249121864
-
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
-
Dhawan S, Tschen SI, Bhushan A. Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation. Genes Dev. 2009;23:906-911.
-
(2009)
Genes Dev
, vol.23
, pp. 906-911
-
-
Dhawan, S.1
Tschen, S.I.2
Bhushan, A.3
-
94
-
-
1342289563
-
Bmi1, stem cells, and senescence regulation
-
Park IK, Morrison SJ, Clarke MF. Bmi1, stem cells, and senescence regulation.J Clin Invest. 2004; 113:175-179.
-
(2004)
J Clin Invest
, vol.113
, pp. 175-179
-
-
Park, I.K.1
Morrison, S.J.2
Clarke, M.F.3
|