Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

Molecular and Cellular Biology

Volumn 27, Issue 23, 2007, Pages 8205-8214

  Li, Han ^a   Vogel, Hannes ^b   Holcomb, Valerie B ^a   Gu, Yansong ^c   Hasty, Paul ^a,d  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KU ANTIGEN; MUTANT PROTEIN; PROTEIN KU80; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER SUSCEPTIBILITY; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE SEQUENCE; IMMUNE DEFICIENCY; IONIZING RADIATION; LIFESPAN; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; TELOMERE;

AGING, PREMATURE; ANIMALS; ANTIGENS, NUCLEAR; CHROMOSOMAL INSTABILITY; DNA-BINDING PROTEINS; FEMUR; GENE DELETION; IN SITU HYBRIDIZATION, FLUORESCENCE; LONGEVITY; MICE; NEOPLASMS;

MUS;

EID: 36849088515     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00785-07     Document Type: Article

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