A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

Nature

Volumn 444, Issue 7122, 2006, Pages 1038-1043

  Niedernhofer, Laura J ^a,b   Garinis, George A ^a   Raams, Anja ^a   Lalai, Astrid S ^a   Robinson, Andria Rasile ^b   Appeldoorn, Esther ^a   Odijk, Hanny ^a   Oostendorp, Roos ^a   Ahmad, Anwaar ^b   Van Leeuwen, Wibeke ^a   Theil, Arjan F ^a   Vermeulen, Wim ^a   Van Der Horst, Gijsbertus T J ^a   Meinecke, Peter ^c   Kleijer, Wim J ^a   Vijg, Jan ^d   Jaspers, Nicolaas G J ^a   Hoeijmakers, Jan H J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c Altonaer Kinderkrankenhaus   (Germany)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; GROWTH HORMONE; NUCLEIC ACID BINDING PROTEIN; SOMATOMEDIN C; TRANSCRIPTOME; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP F PROTEIN;

DNA; GENOTOXICITY; LESION; MODEL; MUTATION; RODENT;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOSYNTHESIS; CALORIC RESTRICTION; CELL DEATH; DNA DAMAGE; DNA REPAIR; EMBRYO; GENOTOXICITY; GROWTH HORMONE SECRETING CELL; HORMONE ACTION; HUMAN; HUMAN CELL; LIFESPAN; LIVER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGERIA; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WILD TYPE;

XERODERMA PIGMENTOSUM;

EID: 33845914051     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05456     Document Type: Article

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