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Volumn 59, Issue , 2013, Pages 155-201

Toll-Like Receptors in Liver Disease

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EID: 84870986481     PISSN: 00652423     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-405211-6.00006-1     Document Type: Chapter
Times cited : (79)

References (302)
  • 1
    • 34748888432 scopus 로고    scopus 로고
    • Deaths: final data for 2004
    • Centers for Disease Control and Prevention National Center for Health Statistics National Vital Statistics System
    • Minino A.M., Heron M.P., Murphy S.L., Kochanek K.D., Centers for Disease Control and Prevention National Center for Health Statistics National Vital Statistics System Deaths: final data for 2004. Natl. Vital Stat. Rep. 2007, 55:1-119.
    • (2007) Natl. Vital Stat. Rep. , vol.55 , pp. 1-119
    • Minino, A.M.1    Heron, M.P.2    Murphy, S.L.3    Kochanek, K.D.4
  • 2
    • 0030611028 scopus 로고    scopus 로고
    • Trends of liver cirrhosis mortality in Europe, 1970-1989: age-period-cohort analysis and changing alcohol consumption
    • Corrao G., Ferrari P., Zambon A., Torchio P., Arico S., Decarli A. Trends of liver cirrhosis mortality in Europe, 1970-1989: age-period-cohort analysis and changing alcohol consumption. Int. J. Epidemiol. 1997, 26:100-109.
    • (1997) Int. J. Epidemiol. , vol.26 , pp. 100-109
    • Corrao, G.1    Ferrari, P.2    Zambon, A.3    Torchio, P.4    Arico, S.5    Decarli, A.6
  • 4
    • 18444393386 scopus 로고    scopus 로고
    • Burden of liver disease in the United States: summary of a workshop
    • Kim W.R., Brown R.S., Terrault N.A., El-Serag H. Burden of liver disease in the United States: summary of a workshop. Hepatology 2002, 36:227-242.
    • (2002) Hepatology , vol.36 , pp. 227-242
    • Kim, W.R.1    Brown, R.S.2    Terrault, N.A.3    El-Serag, H.4
  • 6
    • 77956805892 scopus 로고    scopus 로고
    • Toll-like receptors in the pathogenesis of alcoholic liver disease
    • 710381 (Epub 2010 Aug 17)
    • Petrasek J., Mandrekar P., Szabo G. Toll-like receptors in the pathogenesis of alcoholic liver disease. Gastroenterol. Res. Pract. 2010, 2010. 710381 (Epub 2010 Aug 17).
    • (2010) Gastroenterol. Res. Pract. , vol.2010
    • Petrasek, J.1    Mandrekar, P.2    Szabo, G.3
  • 7
    • 58849132562 scopus 로고    scopus 로고
    • A recent perspective on alcohol, immunity, and host defense
    • Szabo G., Mandrekar P. A recent perspective on alcohol, immunity, and host defense. Alcohol. Clin. Exp. Res. 2009, 33:220-232.
    • (2009) Alcohol. Clin. Exp. Res. , vol.33 , pp. 220-232
    • Szabo, G.1    Mandrekar, P.2
  • 14
    • 34250821655 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediated cytoprotection against liver ischemia and reperfusion injury: inhibition of type-1 interferon signaling
    • Tsuchihashi S., Zhai Y., Bo Q., Busuttil R.W., Kupiec-Weglinski J.W. Heme oxygenase-1 mediated cytoprotection against liver ischemia and reperfusion injury: inhibition of type-1 interferon signaling. Transplantation 2007, 83:1628-1634.
    • (2007) Transplantation , vol.83 , pp. 1628-1634
    • Tsuchihashi, S.1    Zhai, Y.2    Bo, Q.3    Busuttil, R.W.4    Kupiec-Weglinski, J.W.5
  • 15
    • 69949084324 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotide triggers the liver inflammatory reaction and abrogates spontaneous tolerance
    • Ma L.L., Gao X., Liu L., Xiang Z., Blackwell T.S., Williams P., Chari R.S., Yin D.P. CpG oligodeoxynucleotide triggers the liver inflammatory reaction and abrogates spontaneous tolerance. Liver Transpl. 2009, 15:915-923.
    • (2009) Liver Transpl. , vol.15 , pp. 915-923
    • Ma, L.L.1    Gao, X.2    Liu, L.3    Xiang, Z.4    Blackwell, T.S.5    Williams, P.6    Chari, R.S.7    Yin, D.P.8
  • 16
    • 66349110620 scopus 로고    scopus 로고
    • Toll-like receptors as targets in chronic liver diseases
    • Mencin A., Kluwe J., Schwabe R.F. Toll-like receptors as targets in chronic liver diseases. Gut 2009, 58:704-720.
    • (2009) Gut , vol.58 , pp. 704-720
    • Mencin, A.1    Kluwe, J.2    Schwabe, R.F.3
  • 17
    • 39549097751 scopus 로고    scopus 로고
    • Liver: an organ with predominant innate immunity
    • Gao B., Jeong W.I., Tian Z. Liver: an organ with predominant innate immunity. Hepatology 2008, 47:729-736.
    • (2008) Hepatology , vol.47 , pp. 729-736
    • Gao, B.1    Jeong, W.I.2    Tian, Z.3
  • 18
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 2010, 11:373-384.
    • (2010) Nat. Immunol. , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 19
    • 13544263583 scopus 로고    scopus 로고
    • Low TLR4 expression by liver dendritic cells correlates with reduced capacity to activate allogeneic T cells in response to endotoxin
    • De Creus A., Abe M., Lau A.H., Hackstein H., Raimondi G., Thomson A.W. Low TLR4 expression by liver dendritic cells correlates with reduced capacity to activate allogeneic T cells in response to endotoxin. J. Immunol. 2005, 174:2037-2045.
    • (2005) J. Immunol. , vol.174 , pp. 2037-2045
    • De Creus, A.1    Abe, M.2    Lau, A.H.3    Hackstein, H.4    Raimondi, G.5    Thomson, A.W.6
  • 20
    • 47149105036 scopus 로고    scopus 로고
    • Toll-like receptors and adaptor molecules in liver disease: update
    • Seki E., Brenner D.A. Toll-like receptors and adaptor molecules in liver disease: update. Hepatology 2008, 48:322-335.
    • (2008) Hepatology , vol.48 , pp. 322-335
    • Seki, E.1    Brenner, D.A.2
  • 21
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: critical proteins linking innate and acquired immunity
    • Akira S., Takeda K., Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2001, 2:675-680.
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 22
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 24
    • 0025166114 scopus 로고
    • CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
    • Wright S.D., Ramos R.A., Tobias P.S., Ulevitch R.J., Mathison J.C. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 1990, 249:1431-1433.
    • (1990) Science , vol.249 , pp. 1431-1433
    • Wright, S.D.1    Ramos, R.A.2    Tobias, P.S.3    Ulevitch, R.J.4    Mathison, J.C.5
  • 25
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • Shimazu R., Akashi S., Ogata H., Nagai Y., Fukudome K., Miyake K., Kimoto M. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 1999, 189:1777-1782.
    • (1999) J. Exp. Med. , vol.189 , pp. 1777-1782
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3    Nagai, Y.4    Fukudome, K.5    Miyake, K.6    Kimoto, M.7
  • 26
    • 0024464813 scopus 로고
    • Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages
    • Wright S.D., Tobias P.S., Ulevitch R.J., Ramos R.A. Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages. J. Exp. Med. 1989, 170:1231-1241.
    • (1989) J. Exp. Med. , vol.170 , pp. 1231-1241
    • Wright, S.D.1    Tobias, P.S.2    Ulevitch, R.J.3    Ramos, R.A.4
  • 27
    • 0036954037 scopus 로고    scopus 로고
    • Recognition of lipopeptides by Toll-like receptors
    • Takeda K., Takeuchi O., Akira S. Recognition of lipopeptides by Toll-like receptors. J. Endotoxin Res. 2002, 8:459-463.
    • (2002) J. Endotoxin Res. , vol.8 , pp. 459-463
    • Takeda, K.1    Takeuchi, O.2    Akira, S.3
  • 29
    • 56549116047 scopus 로고    scopus 로고
    • Toll-like receptor and RIG-I-like receptor signaling
    • Kawai T., Akira S. Toll-like receptor and RIG-I-like receptor signaling. Ann. N. Y. Acad. Sci. 2008, 1143:1-20.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1143 , pp. 1-20
    • Kawai, T.1    Akira, S.2
  • 30
    • 31344461659 scopus 로고    scopus 로고
    • Innate immune recognition of viral infection
    • Kawai T., Akira S. Innate immune recognition of viral infection. Nat. Immunol. 2006, 7:131-137.
    • (2006) Nat. Immunol. , vol.7 , pp. 131-137
    • Kawai, T.1    Akira, S.2
  • 32
    • 0032774579 scopus 로고    scopus 로고
    • Abnormal DNA methylation and deoxycytosine-deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis
    • Huck S., Deveaud E., Namane A., Zouali M. Abnormal DNA methylation and deoxycytosine-deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis. FASEB J. 1999, 13:1415-1422.
    • (1999) FASEB J. , vol.13 , pp. 1415-1422
    • Huck, S.1    Deveaud, E.2    Namane, A.3    Zouali, M.4
  • 33
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S., Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 2004, 4:499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 34
    • 33646908228 scopus 로고    scopus 로고
    • Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
    • Kagan J.C., Medzhitov R. Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 2006, 125:943-955.
    • (2006) Cell , vol.125 , pp. 943-955
    • Kagan, J.C.1    Medzhitov, R.2
  • 37
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember K.A., Godowski P.J. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J. Immunol. 2002, 168:554-561.
    • (2002) J. Immunol. , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 38
    • 0034070414 scopus 로고    scopus 로고
    • Kupffer cell activation by lipopolysaccharide in rats: role for lipopolysaccharide binding protein and toll-like receptor 4
    • Su G.L., Klein R.D., Aminlari A., Zhang H.Y., Steinstraesser L., Alarcon W.H., Remick D.G., Wang S.C. Kupffer cell activation by lipopolysaccharide in rats: role for lipopolysaccharide binding protein and toll-like receptor 4. Hepatology 2000, 31:932-936.
    • (2000) Hepatology , vol.31 , pp. 932-936
    • Su, G.L.1    Klein, R.D.2    Aminlari, A.3    Zhang, H.Y.4    Steinstraesser, L.5    Alarcon, W.H.6    Remick, D.G.7    Wang, S.C.8
  • 39
    • 0024207738 scopus 로고
    • Cellular and subcellular distribution of injected lipopolysaccharide in rat liver and its inactivation by bile salts
    • Van Bossuyt H., De Zanger R.B., Wisse E. Cellular and subcellular distribution of injected lipopolysaccharide in rat liver and its inactivation by bile salts. J. Hepatol. 1988, 7:325-337.
    • (1988) J. Hepatol. , vol.7 , pp. 325-337
    • Van Bossuyt, H.1    De Zanger, R.B.2    Wisse, E.3
  • 40
    • 0024543089 scopus 로고
    • Clearance of gut-derived endotoxins by the liver. Release and modification of 3H, 14C-lipopolysaccharide by isolated rat Kupffer cells
    • Fox E.S., Thomas P., Broitman S.A. Clearance of gut-derived endotoxins by the liver. Release and modification of 3H, 14C-lipopolysaccharide by isolated rat Kupffer cells. Gastroenterology 1989, 96:456-461.
    • (1989) Gastroenterology , vol.96 , pp. 456-461
    • Fox, E.S.1    Thomas, P.2    Broitman, S.A.3
  • 41
    • 0031616635 scopus 로고    scopus 로고
    • Role of hepatocytes in the clearance of lipopolysaccharide and its clinical significance
    • Tanikawa K., Mimura Y., Sakisaka S., Noguchi K. Role of hepatocytes in the clearance of lipopolysaccharide and its clinical significance. Prog. Clin. Biol. Res. 1998, 397:191-198.
    • (1998) Prog. Clin. Biol. Res. , vol.397 , pp. 191-198
    • Tanikawa, K.1    Mimura, Y.2    Sakisaka, S.3    Noguchi, K.4
  • 42
    • 0035865249 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta
    • Seki E., Tsutsui H., Nakano H., Tsuji N., Hoshino K., Adachi O., Adachi K., Futatsugi S., Kuida K., Takeuchi O., et al. Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta. J. Immunol. 2001, 166:2651-2657.
    • (2001) J. Immunol. , vol.166 , pp. 2651-2657
    • Seki, E.1    Tsutsui, H.2    Nakano, H.3    Tsuji, N.4    Hoshino, K.5    Adachi, O.6    Adachi, K.7    Futatsugi, S.8    Kuida, K.9    Takeuchi, O.10
  • 43
    • 0036785630 scopus 로고    scopus 로고
    • Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice
    • Seki E., Tsutsui H., Tsuji N.M., Hayashi N., Adachi K., Nakano H., Futatsugi-Yumikura S., Takeuchi O., Hoshino K., Akira S., et al. Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice. J. Immunol. 2002, 169:3863-3868.
    • (2002) J. Immunol. , vol.169 , pp. 3863-3868
    • Seki, E.1    Tsutsui, H.2    Tsuji, N.M.3    Hayashi, N.4    Adachi, K.5    Nakano, H.6    Futatsugi-Yumikura, S.7    Takeuchi, O.8    Hoshino, K.9    Akira, S.10
  • 45
    • 33646347356 scopus 로고    scopus 로고
    • Toll-like receptor signaling in the liver
    • Schwabe R.F., Seki E., Brenner D.A. Toll-like receptor signaling in the liver. Gastroenterology 2006, 130:1886-1900.
    • (2006) Gastroenterology , vol.130 , pp. 1886-1900
    • Schwabe, R.F.1    Seki, E.2    Brenner, D.A.3
  • 46
    • 0031859333 scopus 로고    scopus 로고
    • LPS receptor CD14 participates in release of TNF-alpha in RAW 264.7 and peritoneal cells but not in kupffer cells
    • Lichtman S.N., Wang J., Lemasters J.J. LPS receptor CD14 participates in release of TNF-alpha in RAW 264.7 and peritoneal cells but not in kupffer cells. Am. J. Physiol. 1998, 275:G39-G46.
    • (1998) Am. J. Physiol. , vol.275
    • Lichtman, S.N.1    Wang, J.2    Lemasters, J.J.3
  • 48
    • 57649142987 scopus 로고    scopus 로고
    • Beta2-integrin-induced p38 MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes
    • Scott M.J., Billiar T.R. Beta2-integrin-induced p38 MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes. J. Biol. Chem. 2008, 283:29433-29446.
    • (2008) J. Biol. Chem. , vol.283 , pp. 29433-29446
    • Scott, M.J.1    Billiar, T.R.2
  • 52
    • 0242413703 scopus 로고    scopus 로고
    • Lipopolysaccharide activates nuclear factor-kappaB through toll-like receptors and related molecules in cultured biliary epithelial cells
    • Harada K., Ohira S., Isse K., Ozaki S., Zen Y., Sato Y., Nakanuma Y. Lipopolysaccharide activates nuclear factor-kappaB through toll-like receptors and related molecules in cultured biliary epithelial cells. Lab. Invest. 2003, 83:1657-1667.
    • (2003) Lab. Invest. , vol.83 , pp. 1657-1667
    • Harada, K.1    Ohira, S.2    Isse, K.3    Ozaki, S.4    Zen, Y.5    Sato, Y.6    Nakanuma, Y.7
  • 53
    • 28244478101 scopus 로고    scopus 로고
    • Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-kappaB
    • Chen X.M., O'Hara S.P., Nelson J.B., Splinter P.L., Small A.J., Tietz P.S., Limper A.H., LaRusso N.F. Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-kappaB. J. Immunol. 2005, 175:7447-7456.
    • (2005) J. Immunol. , vol.175 , pp. 7447-7456
    • Chen, X.M.1    O'Hara, S.P.2    Nelson, J.B.3    Splinter, P.L.4    Small, A.J.5    Tietz, P.S.6    Limper, A.H.7    LaRusso, N.F.8
  • 55
    • 33645757327 scopus 로고    scopus 로고
    • Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides
    • Martin-Armas M., Simon-Santamaria J., Pettersen I., Moens U., Smedsrod B., Sveinbjornsson B. Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides. J. Hepatol. 2006, 44:939-946.
    • (2006) J. Hepatol. , vol.44 , pp. 939-946
    • Martin-Armas, M.1    Simon-Santamaria, J.2    Pettersen, I.3    Moens, U.4    Smedsrod, B.5    Sveinbjornsson, B.6
  • 57
    • 0346366990 scopus 로고    scopus 로고
    • Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody
    • Asselin-Paturel C., Brizard G., Pin J.J., Briere F., Trinchieri G. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J. Immunol. 2003, 171:6466-6477.
    • (2003) J. Immunol. , vol.171 , pp. 6466-6477
    • Asselin-Paturel, C.1    Brizard, G.2    Pin, J.J.3    Briere, F.4    Trinchieri, G.5
  • 59
    • 58149234003 scopus 로고    scopus 로고
    • Antigen-presenting cells under the influence of alcohol
    • Lau A.H., Szabo G., Thomson A.W. Antigen-presenting cells under the influence of alcohol. Trends Immunol. 2009, 30:13-22.
    • (2009) Trends Immunol. , vol.30 , pp. 13-22
    • Lau, A.H.1    Szabo, G.2    Thomson, A.W.3
  • 60
    • 0018574122 scopus 로고
    • The clearance, tissue distribution, and cellular localization of intravenously injected lipopolysaccharide in rabbits
    • Mathison J.C., Ulevitch R.J. The clearance, tissue distribution, and cellular localization of intravenously injected lipopolysaccharide in rabbits. J. Immunol. 1979, 123:2133-2143.
    • (1979) J. Immunol. , vol.123 , pp. 2133-2143
    • Mathison, J.C.1    Ulevitch, R.J.2
  • 61
    • 0034950477 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice
    • Uesugi T., Froh M., Arteel G.E., Bradford B.U., Thurman R.G. Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology 2001, 34:101-108.
    • (2001) Hepatology , vol.34 , pp. 101-108
    • Uesugi, T.1    Froh, M.2    Arteel, G.E.3    Bradford, B.U.4    Thurman, R.G.5
  • 62
    • 0028108372 scopus 로고
    • Inactivation of Kupffer cells prevents early alcohol-induced liver injury
    • Adachi Y., Bradford B.U., Gao W., Bojes H.K., Thurman R.G. Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 1994, 20:453-460.
    • (1994) Hepatology , vol.20 , pp. 453-460
    • Adachi, Y.1    Bradford, B.U.2    Gao, W.3    Bojes, H.K.4    Thurman, R.G.5
  • 63
    • 0030914902 scopus 로고    scopus 로고
    • Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1
    • Koop D.R., Klopfenstein B., Iimuro Y., Thurman R.G. Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1. Mol. Pharmacol. 1997, 51:944-950.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 944-950
    • Koop, D.R.1    Klopfenstein, B.2    Iimuro, Y.3    Thurman, R.G.4
  • 64
    • 0030716183 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
    • Iimuro Y., Gallucci R.M., Luster M.I., Kono H., Thurman R.G. Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 1997, 26:1530-1537.
    • (1997) Hepatology , vol.26 , pp. 1530-1537
    • Iimuro, Y.1    Gallucci, R.M.2    Luster, M.I.3    Kono, H.4    Thurman, R.G.5
  • 66
    • 84961040091 scopus 로고
    • A quantitative study of the kinetics of blood clearance of P32-labelled Escherichia coli and Staphylococci by the reticuloendothelial system
    • Benacerraf B., Sebestyen M.M., Schlossman S. A quantitative study of the kinetics of blood clearance of P32-labelled Escherichia coli and Staphylococci by the reticuloendothelial system. J. Exp. Med. 1959, 110:27-48.
    • (1959) J. Exp. Med. , vol.110 , pp. 27-48
    • Benacerraf, B.1    Sebestyen, M.M.2    Schlossman, S.3
  • 67
    • 68949178506 scopus 로고    scopus 로고
    • Endotoxemia and gut barrier dysfunction in alcoholic liver disease
    • Rao R. Endotoxemia and gut barrier dysfunction in alcoholic liver disease. Hepatology 2009, 50:638-644.
    • (2009) Hepatology , vol.50 , pp. 638-644
    • Rao, R.1
  • 68
    • 2642553874 scopus 로고    scopus 로고
    • Recent Advances in Alcoholic Liver Disease I. Role of intestinal permeability and endotoxemia in alcoholic liver disease
    • Rao R.K., Seth A., Sheth P. Recent Advances in Alcoholic Liver Disease I. Role of intestinal permeability and endotoxemia in alcoholic liver disease. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 286:G881-G884.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.286
    • Rao, R.K.1    Seth, A.2    Sheth, P.3
  • 69
    • 0028804229 scopus 로고
    • Role of hepatocytes in direct clearance of lipopolysaccharide in rats
    • Mimura Y., Sakisaka S., Harada M., Sata M., Tanikawa K. Role of hepatocytes in direct clearance of lipopolysaccharide in rats. Gastroenterology 1995, 109:1969-1976.
    • (1995) Gastroenterology , vol.109 , pp. 1969-1976
    • Mimura, Y.1    Sakisaka, S.2    Harada, M.3    Sata, M.4    Tanikawa, K.5
  • 70
    • 33745945755 scopus 로고    scopus 로고
    • Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease
    • Medvedev A.E., Sabroe I., Hasday J.D., Vogel S.N. Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease. J. Endotoxin Res. 2006, 12:133-150.
    • (2006) J. Endotoxin Res. , vol.12 , pp. 133-150
    • Medvedev, A.E.1    Sabroe, I.2    Hasday, J.D.3    Vogel, S.N.4
  • 71
    • 2442652487 scopus 로고    scopus 로고
    • HSP60 and CpG-DNA-oligonucleotides differentially regulate LPS-tolerance of hepatic Kupffer cells
    • Schuchmann M., Hermann F., Herkel J., van der Zee R., Galle P.R., Lohse A.W. HSP60 and CpG-DNA-oligonucleotides differentially regulate LPS-tolerance of hepatic Kupffer cells. Immunol. Lett. 2004, 93:199-204.
    • (2004) Immunol. Lett. , vol.93 , pp. 199-204
    • Schuchmann, M.1    Hermann, F.2    Herkel, J.3    van der Zee, R.4    Galle, P.R.5    Lohse, A.W.6
  • 72
    • 0031928131 scopus 로고    scopus 로고
    • Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin
    • Enomoto N., Ikejima K., Bradford B., Rivera C., Kono H., Brenner D.A., Thurman R.G. Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin. Gastroenterology 1998, 115:443-451.
    • (1998) Gastroenterology , vol.115 , pp. 443-451
    • Enomoto, N.1    Ikejima, K.2    Bradford, B.3    Rivera, C.4    Kono, H.5    Brenner, D.A.6    Thurman, R.G.7
  • 76
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani P.D., Bibiloni R., Knauf C., Waget A., Neyrinck A.M., Delzenne N.M., Burcelin R. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008, 57:1470-1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6    Burcelin, R.7
  • 78
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh P.J., Ley R.E., Mahowald M.A., Magrini V., Mardis E.R., Gordon J.I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444:1027-1031.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 81
    • 0021352090 scopus 로고
    • The leaky gut of alcoholism: possible route of entry for toxic compounds
    • Bjarnason I., Peters T.J., Wise R.J. The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet 1984, 1:179-182.
    • (1984) Lancet , vol.1 , pp. 179-182
    • Bjarnason, I.1    Peters, T.J.2    Wise, R.J.3
  • 82
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • Adachi Y., Moore L.E., Bradford B.U., Gao W., Thurman R.G. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995, 108:218-224.
    • (1995) Gastroenterology , vol.108 , pp. 218-224
    • Adachi, Y.1    Moore, L.E.2    Bradford, B.U.3    Gao, W.4    Thurman, R.G.5
  • 87
    • 33747040825 scopus 로고    scopus 로고
    • Pattern recognition receptors: a contemporary view on liver diseases
    • Szabo G., Dolganiuc A., Mandrekar P. Pattern recognition receptors: a contemporary view on liver diseases. Hepatology 2006, 44:287-298.
    • (2006) Hepatology , vol.44 , pp. 287-298
    • Szabo, G.1    Dolganiuc, A.2    Mandrekar, P.3
  • 88
    • 67349205002 scopus 로고    scopus 로고
    • Kupffer cells in non-alcoholic fatty liver disease: the emerging view
    • Baffy G. Kupffer cells in non-alcoholic fatty liver disease: the emerging view. J. Hepatol. 2009, 51:212-223.
    • (2009) J. Hepatol. , vol.51 , pp. 212-223
    • Baffy, G.1
  • 89
    • 0037851770 scopus 로고    scopus 로고
    • Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation
    • Dolganiuc A., Kodys K., Kopasz A., Marshall C., Do T., Romics L., Mandrekar P., Zapp M., Szabo G. Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation. J. Immunol. 2003, 170:5615-5624.
    • (2003) J. Immunol. , vol.170 , pp. 5615-5624
    • Dolganiuc, A.1    Kodys, K.2    Kopasz, A.3    Marshall, C.4    Do, T.5    Romics, L.6    Mandrekar, P.7    Zapp, M.8    Szabo, G.9
  • 90
    • 35649007401 scopus 로고    scopus 로고
    • Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection
    • Dolganiuc A., Norkina O., Kodys K., Catalano D., Bakis G., Marshall C., Mandrekar P., Szabo G. Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection. Gastroenterology 2007, 133:1627-1636.
    • (2007) Gastroenterology , vol.133 , pp. 1627-1636
    • Dolganiuc, A.1    Norkina, O.2    Kodys, K.3    Catalano, D.4    Bakis, G.5    Marshall, C.6    Mandrekar, P.7    Szabo, G.8
  • 94
    • 38849173251 scopus 로고    scopus 로고
    • Comparison of the natural history of alcoholic and nonalcoholic fatty liver disease
    • Mills S.J., Harrison S.A. Comparison of the natural history of alcoholic and nonalcoholic fatty liver disease. Curr. Gastroenterol. Rep. 2005, 7:32-36.
    • (2005) Curr. Gastroenterol. Rep. , vol.7 , pp. 32-36
    • Mills, S.J.1    Harrison, S.A.2
  • 95
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman S.L. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J. Biol. Chem. 2000, 275:2247-2250.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 96
    • 0020593957 scopus 로고
    • Escherichia coli antibodies in alcoholic liver disease. Correlation to alcohol consumption, alcoholic hepatitis, and serum IgA
    • Staun-Olsen P., Bjorneboe M., Prytz H., Thomsen A.C., Orskov F. Escherichia coli antibodies in alcoholic liver disease. Correlation to alcohol consumption, alcoholic hepatitis, and serum IgA. Scand. J. Gastroenterol. 1983, 18:889-896.
    • (1983) Scand. J. Gastroenterol. , vol.18 , pp. 889-896
    • Staun-Olsen, P.1    Bjorneboe, M.2    Prytz, H.3    Thomsen, A.C.4    Orskov, F.5
  • 97
    • 70049099845 scopus 로고    scopus 로고
    • Immune responses to the microbiota at the intestinal mucosal surface
    • Duerkop B.A., Vaishnava S., Hooper L.V. Immune responses to the microbiota at the intestinal mucosal surface. Immunity 2009, 31:368-376.
    • (2009) Immunity , vol.31 , pp. 368-376
    • Duerkop, B.A.1    Vaishnava, S.2    Hooper, L.V.3
  • 98
    • 0028228881 scopus 로고
    • Attenuation of fever and release of cytokines after repeated injections of lipopolysaccharide in guinea-pigs
    • Roth J., McClellan J.L., Kluger M.J., Zeisberger E. Attenuation of fever and release of cytokines after repeated injections of lipopolysaccharide in guinea-pigs. J. Physiol. 1994, 477(Pt 1):177-185.
    • (1994) J. Physiol. , vol.477 , Issue.PART 1 , pp. 177-185
    • Roth, J.1    McClellan, J.L.2    Kluger, M.J.3    Zeisberger, E.4
  • 100
    • 0026078067 scopus 로고
    • Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay
    • Fukui H., Brauner B., Bode J.C., Bode C. Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay. J. Hepatol. 1991, 12:162-169.
    • (1991) J. Hepatol. , vol.12 , pp. 162-169
    • Fukui, H.1    Brauner, B.2    Bode, J.C.3    Bode, C.4
  • 101
    • 0028220726 scopus 로고
    • Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease)
    • Nanji A.A., Khettry U., Sadrzadeh S.M. Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease). Proc. Soc. Exp. Biol. Med. 1994, 205:243-247.
    • (1994) Proc. Soc. Exp. Biol. Med. , vol.205 , pp. 243-247
    • Nanji, A.A.1    Khettry, U.2    Sadrzadeh, S.M.3
  • 102
    • 38349109046 scopus 로고    scopus 로고
    • Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease
    • Tang Y., Banan A., Forsyth C.B., Fields J.Z., Lau C.K., Zhang L.J., Keshavarzian A. Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease. Alcohol. Clin. Exp. Res. 2008, 32:355-364.
    • (2008) Alcohol. Clin. Exp. Res. , vol.32 , pp. 355-364
    • Tang, Y.1    Banan, A.2    Forsyth, C.B.3    Fields, J.Z.4    Lau, C.K.5    Zhang, L.J.6    Keshavarzian, A.7
  • 104
    • 0032185432 scopus 로고    scopus 로고
    • II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin
    • Thurman R.G. II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin. Am. J. Physiol. 1998, 275:G605-G611.
    • (1998) Am. J. Physiol. , vol.275
    • Thurman, R.G.1
  • 105
    • 79959811718 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice
    • Inokuchi S., Tsukamoto H., Park E., Liu Z.X., Brenner D.A., Seki E. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcohol. Clin. Exp. Res. 2011, 35:1509-1518.
    • (2011) Alcohol. Clin. Exp. Res. , vol.35 , pp. 1509-1518
    • Inokuchi, S.1    Tsukamoto, H.2    Park, E.3    Liu, Z.X.4    Brenner, D.A.5    Seki, E.6
  • 110
    • 28844447087 scopus 로고    scopus 로고
    • Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes
    • Romics L., Dolganiuc A., Velayudham A., Kodys K., Mandrekar P., Golenbock D., Kurt-Jones E., Szabo G. Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes. J. Leukoc. Biol. 2005, 78:1255-1264.
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 1255-1264
    • Romics, L.1    Dolganiuc, A.2    Velayudham, A.3    Kodys, K.4    Mandrekar, P.5    Golenbock, D.6    Kurt-Jones, E.7    Szabo, G.8
  • 112
    • 69949154152 scopus 로고    scopus 로고
    • Increased immunoglobulin A in alcoholic liver cirrhosis: exploring the response of B cells to Toll-like receptor 9 activation
    • Massonnet B., Delwail A., Ayrault J.M., Chagneau-Derrode C., Lecron J.C., Silvain C. Increased immunoglobulin A in alcoholic liver cirrhosis: exploring the response of B cells to Toll-like receptor 9 activation. Clin. Exp. Immunol. 2009, 158:115-124.
    • (2009) Clin. Exp. Immunol. , vol.158 , pp. 115-124
    • Massonnet, B.1    Delwail, A.2    Ayrault, J.M.3    Chagneau-Derrode, C.4    Lecron, J.C.5    Silvain, C.6
  • 114
    • 34547193134 scopus 로고    scopus 로고
    • Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity
    • Malhi H., Barreyro F.J., Isomoto H., Bronk S.F., Gores G.J. Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity. Gut 2007, 56:1124-1131.
    • (2007) Gut , vol.56 , pp. 1124-1131
    • Malhi, H.1    Barreyro, F.J.2    Isomoto, H.3    Bronk, S.F.4    Gores, G.J.5
  • 117
    • 54449092214 scopus 로고    scopus 로고
    • The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88
    • Hritz I., Mandrekar P., Velayudham A., Catalano D., Dolganiuc A., Kodys K., Kurt-Jones E., Szabo G. The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. Hepatology 2008, 48:1224-1231.
    • (2008) Hepatology , vol.48 , pp. 1224-1231
    • Hritz, I.1    Mandrekar, P.2    Velayudham, A.3    Catalano, D.4    Dolganiuc, A.5    Kodys, K.6    Kurt-Jones, E.7    Szabo, G.8
  • 118
    • 79251482742 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells
    • Petrasek J., Dolganiuc A., Csak T., Nath B., Hritz I., Kodys K., Catalano D., Kurt-Jones E., Mandrekar P., Szabo G. Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. Hepatology 2011, 53:649-660.
    • (2011) Hepatology , vol.53 , pp. 649-660
    • Petrasek, J.1    Dolganiuc, A.2    Csak, T.3    Nath, B.4    Hritz, I.5    Kodys, K.6    Catalano, D.7    Kurt-Jones, E.8    Mandrekar, P.9    Szabo, G.10
  • 119
    • 0036308245 scopus 로고    scopus 로고
    • Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription
    • Morin P., Braganca J., Bandu M.T., Lin R., Hiscott J., Doly J., Civas A. Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription. J. Mol. Biol. 2002, 316:1009-1022.
    • (2002) J. Mol. Biol. , vol.316 , pp. 1009-1022
    • Morin, P.1    Braganca, J.2    Bandu, M.T.3    Lin, R.4    Hiscott, J.5    Doly, J.6    Civas, A.7
  • 120
    • 51549118941 scopus 로고    scopus 로고
    • TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol
    • Zhao X.J., Dong Q., Bindas J., Piganelli J.D., Magill A., Reiser J., Kolls J.K. TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol. J. Immunol. 2008, 181:3049-3056.
    • (2008) J. Immunol. , vol.181 , pp. 3049-3056
    • Zhao, X.J.1    Dong, Q.2    Bindas, J.3    Piganelli, J.D.4    Magill, A.5    Reiser, J.6    Kolls, J.K.7
  • 121
    • 55149094739 scopus 로고    scopus 로고
    • Interleukin-10: new perspectives on an old cytokine
    • Mosser D.M., Zhang X. Interleukin-10: new perspectives on an old cytokine. Immunol. Rev. 2008, 226:205-218.
    • (2008) Immunol. Rev. , vol.226 , pp. 205-218
    • Mosser, D.M.1    Zhang, X.2
  • 122
    • 67349255858 scopus 로고    scopus 로고
    • Signalling pathways in alcohol-induced liver inflammation
    • Mandrekar P., Szabo G. Signalling pathways in alcohol-induced liver inflammation. J. Hepatol. 2009, 50:1258-1266.
    • (2009) J. Hepatol. , vol.50 , pp. 1258-1266
    • Mandrekar, P.1    Szabo, G.2
  • 123
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: new discoveries and insights
    • Baldwin A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 1996, 14:649-683.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 124
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
    • Ghosh S., May M.J., Kopp E.B. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 1998, 16:225-260.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 125
    • 77954157280 scopus 로고    scopus 로고
    • Ethanol augments RANTES/CCL5 expression in rat liver sinusoidal endothelial cells and human endothelial cells via activation of NF-kappa B, HIF-1 alpha, and AP-1
    • Yeligar S.M., Machida K., Tsukamoto H., Kalra V.K. Ethanol augments RANTES/CCL5 expression in rat liver sinusoidal endothelial cells and human endothelial cells via activation of NF-kappa B, HIF-1 alpha, and AP-1. J. Immunol. 2009, 183:5964-5976.
    • (2009) J. Immunol. , vol.183 , pp. 5964-5976
    • Yeligar, S.M.1    Machida, K.2    Tsukamoto, H.3    Kalra, V.K.4
  • 126
    • 0037177899 scopus 로고    scopus 로고
    • Chronic ethanol increases lipopolysaccharide-stimulated Egr-1 expression in RAW 264.7 macrophages: contribution to enhanced tumor necrosis factor alpha production
    • Shi L., Kishore R., McMullen M.R., Nagy L.E. Chronic ethanol increases lipopolysaccharide-stimulated Egr-1 expression in RAW 264.7 macrophages: contribution to enhanced tumor necrosis factor alpha production. J. Biol. Chem. 2002, 277:14777-14785.
    • (2002) J. Biol. Chem. , vol.277 , pp. 14777-14785
    • Shi, L.1    Kishore, R.2    McMullen, M.R.3    Nagy, L.E.4
  • 127
    • 20444477804 scopus 로고    scopus 로고
    • Early growth response-1 transcription factor is essential for ethanol-induced fatty liver injury in mice
    • McMullen M.R., Pritchard M.T., Wang Q., Millward C.A., Croniger C.M., Nagy L.E. Early growth response-1 transcription factor is essential for ethanol-induced fatty liver injury in mice. Gastroenterology 2005, 128:2066-2076.
    • (2005) Gastroenterology , vol.128 , pp. 2066-2076
    • McMullen, M.R.1    Pritchard, M.T.2    Wang, Q.3    Millward, C.A.4    Croniger, C.M.5    Nagy, L.E.6
  • 128
    • 7044260441 scopus 로고    scopus 로고
    • Liver hypoxia and lack of recovery after reperfusion at high blood alcohol levels in the intragastric feeding model of alcohol liver disease
    • Li J., French B., Wu Y., Vanketesh R., Montgomery R., Bardag-Gorce F., Kitto J., French S.W. Liver hypoxia and lack of recovery after reperfusion at high blood alcohol levels in the intragastric feeding model of alcohol liver disease. Exp. Mol. Pathol. 2004, 77:184-192.
    • (2004) Exp. Mol. Pathol. , vol.77 , pp. 184-192
    • Li, J.1    French, B.2    Wu, Y.3    Vanketesh, R.4    Montgomery, R.5    Bardag-Gorce, F.6    Kitto, J.7    French, S.W.8
  • 129
    • 79955096123 scopus 로고    scopus 로고
    • Hepatocyte-specific hypoxia-inducible factor-1alpha is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice
    • Nath B., Levin I., Csak T., Petrasek J., Mueller C., Kodys K., Catalano D., Mandrekar P., Szabo G. Hepatocyte-specific hypoxia-inducible factor-1alpha is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice. Hepatology 2011, 53:1526-1537.
    • (2011) Hepatology , vol.53 , pp. 1526-1537
    • Nath, B.1    Levin, I.2    Csak, T.3    Petrasek, J.4    Mueller, C.5    Kodys, K.6    Catalano, D.7    Mandrekar, P.8    Szabo, G.9
  • 131
    • 31344437783 scopus 로고    scopus 로고
    • Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein
    • Chang B.H., Li L., Paul A., Taniguchi S., Nannegari V., Heird W.C., Chan L. Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein. Mol. Cell. Biol. 2006, 26:1063-1076.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 1063-1076
    • Chang, B.H.1    Li, L.2    Paul, A.3    Taniguchi, S.4    Nannegari, V.5    Heird, W.C.6    Chan, L.7
  • 133
    • 23044454592 scopus 로고    scopus 로고
    • Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
    • Apte U.M., Banerjee A., McRee R., Wellberg E., Ramaiah S.K. Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis. Toxicol. Appl. Pharmacol. 2005, 207:25-38.
    • (2005) Toxicol. Appl. Pharmacol. , vol.207 , pp. 25-38
    • Apte, U.M.1    Banerjee, A.2    McRee, R.3    Wellberg, E.4    Ramaiah, S.K.5
  • 134
    • 34548380904 scopus 로고    scopus 로고
    • Hepatic neutrophil infiltration in the pathogenesis of alcohol-induced liver injury
    • Ramaiah S.K., Jaeschke H. Hepatic neutrophil infiltration in the pathogenesis of alcohol-induced liver injury. Toxicol. Mech. Methods 2007, 17:431-440.
    • (2007) Toxicol. Mech. Methods , vol.17 , pp. 431-440
    • Ramaiah, S.K.1    Jaeschke, H.2
  • 136
    • 70349662172 scopus 로고    scopus 로고
    • Tumor necrosis factor polymorphisms and alcoholic liver disease: a HuGE review and meta-analysis
    • Marcos M., Gomez-Munuera M., Pastor I., Gonzalez-Sarmiento R., Laso F.J. Tumor necrosis factor polymorphisms and alcoholic liver disease: a HuGE review and meta-analysis. Am. J. Epidemiol. 2009, 170:948-956.
    • (2009) Am. J. Epidemiol. , vol.170 , pp. 948-956
    • Marcos, M.1    Gomez-Munuera, M.2    Pastor, I.3    Gonzalez-Sarmiento, R.4    Laso, F.J.5
  • 138
    • 78651399501 scopus 로고    scopus 로고
    • Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor alpha (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease
    • Bala S., Marcos M., Kodys K., Csak T., Catalano D., Mandrekar P., Szabo G. Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor alpha (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease. J. Biol. Chem. 2011, 286:1436-1444.
    • (2011) J. Biol. Chem. , vol.286 , pp. 1436-1444
    • Bala, S.1    Marcos, M.2    Kodys, K.3    Csak, T.4    Catalano, D.5    Mandrekar, P.6    Szabo, G.7
  • 139
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: a beautiful pathway
    • Chen G., Goeddel D.V. TNF-R1 signaling: a beautiful pathway. Science 2002, 296:1634-1635.
    • (2002) Science , vol.296 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 140
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: integrating mammalian biology
    • Locksley R.M., Killeen N., Lenardo M.J. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 2001, 104:487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 141
    • 62849093368 scopus 로고    scopus 로고
    • Death receptor signal transducers: nodes of coordination in immune signaling networks
    • Wilson N.S., Dixit V., Ashkenazi A. Death receptor signal transducers: nodes of coordination in immune signaling networks. Nat. Immunol. 2009, 10:348-355.
    • (2009) Nat. Immunol. , vol.10 , pp. 348-355
    • Wilson, N.S.1    Dixit, V.2    Ashkenazi, A.3
  • 142
    • 0034015563 scopus 로고    scopus 로고
    • Ethanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition
    • Pastorino J.G., Hoek J.B. Ethanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition. Hepatology 2000, 31:1141-1152.
    • (2000) Hepatology , vol.31 , pp. 1141-1152
    • Pastorino, J.G.1    Hoek, J.B.2
  • 143
    • 0032881294 scopus 로고    scopus 로고
    • Chronic ethanol consumption causes alterations in the structural integrity of mitochondrial DNA in aged rats
    • Cahill A., Stabley G.J., Wang X., Hoek J.B. Chronic ethanol consumption causes alterations in the structural integrity of mitochondrial DNA in aged rats. Hepatology 1999, 30:881-888.
    • (1999) Hepatology , vol.30 , pp. 881-888
    • Cahill, A.1    Stabley, G.J.2    Wang, X.3    Hoek, J.B.4
  • 145
    • 34250782784 scopus 로고    scopus 로고
    • Alcohol-induced S-adenosylhomocysteine accumulation in the liver sensitizes to TNF hepatotoxicity: possible involvement of mitochondrial S-adenosylmethionine transport
    • Song Z., Zhou Z., Song M., Uriarte S., Chen T., Deaciuc I., McClain C.J. Alcohol-induced S-adenosylhomocysteine accumulation in the liver sensitizes to TNF hepatotoxicity: possible involvement of mitochondrial S-adenosylmethionine transport. Biochem. Pharmacol. 2007, 74:521-531.
    • (2007) Biochem. Pharmacol. , vol.74 , pp. 521-531
    • Song, Z.1    Zhou, Z.2    Song, M.3    Uriarte, S.4    Chen, T.5    Deaciuc, I.6    McClain, C.J.7
  • 146
  • 148
    • 0032570828 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase
    • Lawler J.F., Yin M., Diehl A.M., Roberts E., Chatterjee S. Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase. J. Biol. Chem. 1998, 273:5053-5059.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5053-5059
    • Lawler, J.F.1    Yin, M.2    Diehl, A.M.3    Roberts, E.4    Chatterjee, S.5
  • 149
    • 68949192626 scopus 로고    scopus 로고
    • Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway
    • Raetzsch C.F., Brooks N.L., Alderman J.M., Moore K.S., Hosick P.A., Klebanov S., Akira S., Bear J.E., Baldwin A.S., Mackman N., et al. Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway. Hepatology 2009, 50:592-600.
    • (2009) Hepatology , vol.50 , pp. 592-600
    • Raetzsch, C.F.1    Brooks, N.L.2    Alderman, J.M.3    Moore, K.S.4    Hosick, P.A.5    Klebanov, S.6    Akira, S.7    Bear, J.E.8    Baldwin, A.S.9    Mackman, N.10
  • 150
    • 0028815553 scopus 로고
    • Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance
    • Berg D.J., Kuhn R., Rajewsky K., Muller W., Menon S., Davidson N., Grunig G., Rennick D. Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. J. Clin. Invest. 1995, 96:2339-2347.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2339-2347
    • Berg, D.J.1    Kuhn, R.2    Rajewsky, K.3    Muller, W.4    Menon, S.5    Davidson, N.6    Grunig, G.7    Rennick, D.8
  • 151
    • 80052005701 scopus 로고    scopus 로고
    • Inflammation-associated IL-6/STAT3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in IL-10 deficient mice
    • Miller A.M., Wang H., Bertola A., Park O., Horiguchi N., Ki S.H., Yin S., Lafdil F., Gao B. Inflammation-associated IL-6/STAT3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in IL-10 deficient mice. Hepatology 2011, 54:846-856.
    • (2011) Hepatology , vol.54 , pp. 846-856
    • Miller, A.M.1    Wang, H.2    Bertola, A.3    Park, O.4    Horiguchi, N.5    Ki, S.H.6    Yin, S.7    Lafdil, F.8    Gao, B.9
  • 154
    • 0032990966 scopus 로고    scopus 로고
    • IL-18-deficient mice are resistant to endotoxin-induced liver injury but highly susceptible to endotoxin shock
    • Sakao Y., Takeda K., Tsutsui H., Kaisho T., Nomura F., Okamura H., Nakanishi K., Akira S. IL-18-deficient mice are resistant to endotoxin-induced liver injury but highly susceptible to endotoxin shock. Int. Immunol. 1999, 11:471-480.
    • (1999) Int. Immunol. , vol.11 , pp. 471-480
    • Sakao, Y.1    Takeda, K.2    Tsutsui, H.3    Kaisho, T.4    Nomura, F.5    Okamura, H.6    Nakanishi, K.7    Akira, S.8
  • 155
    • 47149092247 scopus 로고    scopus 로고
    • An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha
    • Cosgrove B.D., Cheng C., Pritchard J.R., Stolz D.B., Lauffenburger D.A., Griffith L.G. An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha. Hepatology 2008, 48:276-288.
    • (2008) Hepatology , vol.48 , pp. 276-288
    • Cosgrove, B.D.1    Cheng, C.2    Pritchard, J.R.3    Stolz, D.B.4    Lauffenburger, D.A.5    Griffith, L.G.6
  • 156
    • 79251600358 scopus 로고    scopus 로고
    • Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice
    • Petrasek J., Dolganiuc A., Csak T., Kurt-Jones E.A., Szabo G. Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice. Gastroenterology 2011, 140:697-708.e4.
    • (2011) Gastroenterology , vol.140
    • Petrasek, J.1    Dolganiuc, A.2    Csak, T.3    Kurt-Jones, E.A.4    Szabo, G.5
  • 157
    • 0031685777 scopus 로고    scopus 로고
    • Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis
    • Afford S.C., Fisher N.C., Neil D.A., Fear J., Brun P., Hubscher S.G., Adams D.H. Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis. J. Pathol. 1998, 186:82-89.
    • (1998) J. Pathol. , vol.186 , pp. 82-89
    • Afford, S.C.1    Fisher, N.C.2    Neil, D.A.3    Fear, J.4    Brun, P.5    Hubscher, S.G.6    Adams, D.H.7
  • 158
    • 82455167937 scopus 로고    scopus 로고
    • An essential role for MCP-1 in alcoholic liver injury: regulation of pro-inflammatory cytokines and hepatic steatosis
    • Mandrekar P., Ambade A., Lim A., Szabo G., Catalano D. An essential role for MCP-1 in alcoholic liver injury: regulation of pro-inflammatory cytokines and hepatic steatosis. Hepatology 2011, 54:2185-2197.
    • (2011) Hepatology , vol.54 , pp. 2185-2197
    • Mandrekar, P.1    Ambade, A.2    Lim, A.3    Szabo, G.4    Catalano, D.5
  • 159
    • 79959501180 scopus 로고    scopus 로고
    • Emerging role of redox dysregulation in alcoholic and nonalcoholic fatty liver disease
    • Feldstein A.E., Bailey S.M. Emerging role of redox dysregulation in alcoholic and nonalcoholic fatty liver disease. Antioxid. Redox Signal. 2011, 15:421-424.
    • (2011) Antioxid. Redox Signal. , vol.15 , pp. 421-424
    • Feldstein, A.E.1    Bailey, S.M.2
  • 161
    • 0142151776 scopus 로고    scopus 로고
    • Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity
    • Perez M.J., Cederbaum A.I. Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity. Hepatology 2003, 38:1146-1158.
    • (2003) Hepatology , vol.38 , pp. 1146-1158
    • Perez, M.J.1    Cederbaum, A.I.2
  • 162
    • 0035026194 scopus 로고    scopus 로고
    • Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver
    • Bailey S.M., Patel V.B., Young T.A., Asayama K., Cunningham C.C. Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver. Alcohol. Clin. Exp. Res. 2001, 25:726-733.
    • (2001) Alcohol. Clin. Exp. Res. , vol.25 , pp. 726-733
    • Bailey, S.M.1    Patel, V.B.2    Young, T.A.3    Asayama, K.4    Cunningham, C.C.5
  • 163
    • 47749149538 scopus 로고    scopus 로고
    • Ethanol induces peroxynitrite-mediated toxicity through inactivation of NADP+-dependent isocitrate dehydrogenase and superoxide dismutase
    • Yang E.S., Lee J.H., Park J.W. Ethanol induces peroxynitrite-mediated toxicity through inactivation of NADP+-dependent isocitrate dehydrogenase and superoxide dismutase. Biochimie 2008, 90:1316-1324.
    • (2008) Biochimie , vol.90 , pp. 1316-1324
    • Yang, E.S.1    Lee, J.H.2    Park, J.W.3
  • 167
    • 4644350365 scopus 로고    scopus 로고
    • Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa B
    • Park H.S., Jung H.Y., Park E.Y., Kim J., Lee W.J., Bae Y.S. Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa B. J. Immunol. 2004, 173:3589-3593.
    • (2004) J. Immunol. , vol.173 , pp. 3589-3593
    • Park, H.S.1    Jung, H.Y.2    Park, E.Y.3    Kim, J.4    Lee, W.J.5    Bae, Y.S.6
  • 168
    • 58149333718 scopus 로고    scopus 로고
    • High glucose induces toll-like receptor expression in human monocytes: mechanism of activation
    • Dasu M.R., Devaraj S., Zhao L., Hwang D.H., Jialal I. High glucose induces toll-like receptor expression in human monocytes: mechanism of activation. Diabetes 2008, 57:3090-3098.
    • (2008) Diabetes , vol.57 , pp. 3090-3098
    • Dasu, M.R.1    Devaraj, S.2    Zhao, L.3    Hwang, D.H.4    Jialal, I.5
  • 169
    • 84864572232 scopus 로고    scopus 로고
    • The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis
    • Levin I., Petrasek J., Szabo G. The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis. Alcohol. Clin. Exp. Res. 2012, 36:1397-1406. 10.1111/j.1530-0277.2012.01739.x.
    • (2012) Alcohol. Clin. Exp. Res. , vol.36 , pp. 1397-1406
    • Levin, I.1    Petrasek, J.2    Szabo, G.3
  • 171
    • 77649337140 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: pathology and pathogenesis
    • Tiniakos D.G., Vos M.B., Brunt E.M. Nonalcoholic fatty liver disease: pathology and pathogenesis. Annu. Rev. Pathol. 2010, 5:145-171.
    • (2010) Annu. Rev. Pathol. , vol.5 , pp. 145-171
    • Tiniakos, D.G.1    Vos, M.B.2    Brunt, E.M.3
  • 172
    • 21344449292 scopus 로고    scopus 로고
    • Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study
    • Bedogni G., Miglioli L., Masutti F., Tiribelli C., Marchesini G., Bellentani S. Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology 2005, 42:44-52.
    • (2005) Hepatology , vol.42 , pp. 44-52
    • Bedogni, G.1    Miglioli, L.2    Masutti, F.3    Tiribelli, C.4    Marchesini, G.5    Bellentani, S.6
  • 173
    • 79959297962 scopus 로고    scopus 로고
    • Insulin resistance and other metabolic risk factors in the pathogenesis of hepatocellular carcinoma
    • Siddique A., Kowdley K.V. Insulin resistance and other metabolic risk factors in the pathogenesis of hepatocellular carcinoma. Clin. Liver Dis. 2011, 15:281-296.
    • (2011) Clin. Liver Dis. , vol.15 , pp. 281-296
    • Siddique, A.1    Kowdley, K.V.2
  • 174
    • 0037309589 scopus 로고    scopus 로고
    • Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease
    • Li Z., Yang S., Lin H., Huang J., Watkins P.A., Moser A.B., Desimone C., Song X.Y., Diehl A.M. Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 2003, 37:343-350.
    • (2003) Hepatology , vol.37 , pp. 343-350
    • Li, Z.1    Yang, S.2    Lin, H.3    Huang, J.4    Watkins, P.A.5    Moser, A.B.6    Desimone, C.7    Song, X.Y.8    Diehl, A.M.9
  • 175
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: a tale of two "hits" ?
    • Day C.P., James O.F. Steatohepatitis: a tale of two "hits" ?. Gastroenterology 1998, 114:842-845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 176
    • 79959573042 scopus 로고    scopus 로고
    • Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
    • Csak T., Ganz M., Pespisa J., Kodys K., Dolganiuc A., Szabo G. Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology 2011, 54:133-144.
    • (2011) Hepatology , vol.54 , pp. 133-144
    • Csak, T.1    Ganz, M.2    Pespisa, J.3    Kodys, K.4    Dolganiuc, A.5    Szabo, G.6
  • 177
    • 0035125052 scopus 로고    scopus 로고
    • The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis
    • Wigg A.J., Roberts-Thomson I.C., Dymock R.B., McCarthy P.J., Grose R.H., Cummins A.G. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis. Gut 2001, 48:206-211.
    • (2001) Gut , vol.48 , pp. 206-211
    • Wigg, A.J.1    Roberts-Thomson, I.C.2    Dymock, R.B.3    McCarthy, P.J.4    Grose, R.H.5    Cummins, A.G.6
  • 178
    • 34548272744 scopus 로고    scopus 로고
    • Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis
    • Rivera C.A., Adegboyega P., van Rooijen N., Tagalicud A., Allman M., Wallace M. Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis. J. Hepatol. 2007, 47:571-579.
    • (2007) J. Hepatol. , vol.47 , pp. 571-579
    • Rivera, C.A.1    Adegboyega, P.2    van Rooijen, N.3    Tagalicud, A.4    Allman, M.5    Wallace, M.6
  • 180
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley R.E., Turnbaugh P.J., Klein S., Gordon J.I. Microbial ecology: human gut microbes associated with obesity. Nature 2006, 444:1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 182
    • 0037879075 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease: lumen-liver interactions and possible role for probiotics
    • Solga S.F., Diehl A.M. Non-alcoholic fatty liver disease: lumen-liver interactions and possible role for probiotics. J. Hepatol. 2003, 38:681-687.
    • (2003) J. Hepatol. , vol.38 , pp. 681-687
    • Solga, S.F.1    Diehl, A.M.2
  • 183
    • 63349101854 scopus 로고    scopus 로고
    • VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice
    • Velayudham A., Dolganiuc A., Ellis M., Petrasek J., Kodys K., Mandrekar P., Szabo G. VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice. Hepatology 2009, 49:989-997.
    • (2009) Hepatology , vol.49 , pp. 989-997
    • Velayudham, A.1    Dolganiuc, A.2    Ellis, M.3    Petrasek, J.4    Kodys, K.5    Mandrekar, P.6    Szabo, G.7
  • 185
    • 21644472266 scopus 로고    scopus 로고
    • Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression
    • Romics L., Mandrekar P., Kodys K., Velayudham A., Drechsler Y., Dolganiuc A., Szabo G. Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression. Alcohol. Clin. Exp. Res. 2005, 29:1018-1026.
    • (2005) Alcohol. Clin. Exp. Res. , vol.29 , pp. 1018-1026
    • Romics, L.1    Mandrekar, P.2    Kodys, K.3    Velayudham, A.4    Drechsler, Y.5    Dolganiuc, A.6    Szabo, G.7
  • 186
    • 0001513966 scopus 로고    scopus 로고
    • Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis
    • Yang S.Q., Lin H.Z., Lane M.D., Clemens M., Diehl A.M. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc. Natl. Acad. Sci. USA. 1997, 94:2557-2562.
    • (1997) Proc. Natl. Acad. Sci. USA. , vol.94 , pp. 2557-2562
    • Yang, S.Q.1    Lin, H.Z.2    Lane, M.D.3    Clemens, M.4    Diehl, A.M.5
  • 187
    • 70350075402 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice
    • Spruss A., Kanuri G., Wagnerberger S., Haub S., Bischoff S.C., Bergheim I. Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice. Hepatology 2009, 50:1094-1104.
    • (2009) Hepatology , vol.50 , pp. 1094-1104
    • Spruss, A.1    Kanuri, G.2    Wagnerberger, S.3    Haub, S.4    Bischoff, S.C.5    Bergheim, I.6
  • 188
    • 79952230506 scopus 로고    scopus 로고
    • Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease
    • Miura K., Seki E., Ohnishi H., Brenner D.A. Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease. Gastroenterol. Res. Pract. 2010, 2010:362847.
    • (2010) Gastroenterol. Res. Pract. , vol.2010 , pp. 362847
    • Miura, K.1    Seki, E.2    Ohnishi, H.3    Brenner, D.A.4
  • 189
    • 36348997503 scopus 로고    scopus 로고
    • Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9
    • Watanabe A., Hashmi A., Gomes D.A., Town T., Badou A., Flavell R.A., Mehal W.Z. Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology 2007, 46:1509-1518.
    • (2007) Hepatology , vol.46 , pp. 1509-1518
    • Watanabe, A.1    Hashmi, A.2    Gomes, D.A.3    Town, T.4    Badou, A.5    Flavell, R.A.6    Mehal, W.Z.7
  • 191
    • 33748755008 scopus 로고    scopus 로고
    • Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes
    • Senn J.J. Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes. J. Biol. Chem. 2006, 281:26865-26875.
    • (2006) J. Biol. Chem. , vol.281 , pp. 26865-26875
    • Senn, J.J.1
  • 192
    • 73949110679 scopus 로고    scopus 로고
    • Saturated fatty acids do not directly stimulate Toll-like receptor signaling
    • Erridge C., Samani N.J. Saturated fatty acids do not directly stimulate Toll-like receptor signaling. Arterioscler. Thromb. Vasc. Biol. 2009, 29:1944-1949.
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 1944-1949
    • Erridge, C.1    Samani, N.J.2
  • 193
    • 80055043169 scopus 로고    scopus 로고
    • Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice
    • Li L., Chen L., Hu L., Liu Y., Sun H.Y., Tang J., Hou Y.J., Chang Y.X., Tu Q.Q., Feng G.S., et al. Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice. Hepatology 2011, 54:1620-1630.
    • (2011) Hepatology , vol.54 , pp. 1620-1630
    • Li, L.1    Chen, L.2    Hu, L.3    Liu, Y.4    Sun, H.Y.5    Tang, J.6    Hou, Y.J.7    Chang, Y.X.8    Tu, Q.Q.9    Feng, G.S.10
  • 195
    • 30044431801 scopus 로고    scopus 로고
    • From fat to inflammation
    • Day C.P. From fat to inflammation. Gastroenterology 2006, 130:207-210.
    • (2006) Gastroenterology , vol.130 , pp. 207-210
    • Day, C.P.1
  • 197
    • 56649094325 scopus 로고    scopus 로고
    • Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease
    • Malhi H., Gores G.J. Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease. Semin. Liver Dis. 2008, 28:360-369.
    • (2008) Semin. Liver Dis. , vol.28 , pp. 360-369
    • Malhi, H.1    Gores, G.J.2
  • 198
    • 33744948514 scopus 로고    scopus 로고
    • Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis
    • Malhi H., Bronk S.F., Werneburg N.W., Gores G.J. Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis. J. Biol. Chem. 2006, 281:12093-12101.
    • (2006) J. Biol. Chem. , vol.281 , pp. 12093-12101
    • Malhi, H.1    Bronk, S.F.2    Werneburg, N.W.3    Gores, G.J.4
  • 200
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly K.L., Smith C.I., Schwarzenberg S.J., Jessurun J., Boldt M.D., Parks E.J. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 2005, 115:1343-1351.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 202
    • 42949086433 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of liver injury
    • Malhi H., Gores G.J. Cellular and molecular mechanisms of liver injury. Gastroenterology 2008, 134:1641-1654.
    • (2008) Gastroenterology , vol.134 , pp. 1641-1654
    • Malhi, H.1    Gores, G.J.2
  • 203
    • 57649214103 scopus 로고    scopus 로고
    • Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)
    • Musso G., Gambino R., Cassader M. Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD). Prog. Lipid Res. 2009, 48:1-26.
    • (2009) Prog. Lipid Res. , vol.48 , pp. 1-26
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 204
    • 78049522194 scopus 로고    scopus 로고
    • Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis
    • Tilg H., Moschen A.R. Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. Hepatology 2010, 52:1836-1846.
    • (2010) Hepatology , vol.52 , pp. 1836-1846
    • Tilg, H.1    Moschen, A.R.2
  • 206
    • 80054737370 scopus 로고    scopus 로고
    • Lack of interleukin-1alpha or interleukin-1beta inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
    • Kamari Y., Shaish A., Vax E., Shemesh S., Kandel-Kfir M., Arbel Y., Olteanu S., Barshack I., Dotan S., Voronov E., et al. Lack of interleukin-1alpha or interleukin-1beta inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. J. Hepatol. 2011, 55:1086-1094.
    • (2011) J. Hepatol. , vol.55 , pp. 1086-1094
    • Kamari, Y.1    Shaish, A.2    Vax, E.3    Shemesh, S.4    Kandel-Kfir, M.5    Arbel, Y.6    Olteanu, S.7    Barshack, I.8    Dotan, S.9    Voronov, E.10
  • 207
  • 208
    • 75449101395 scopus 로고    scopus 로고
    • Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity
    • Stienstra R., Saudale F., Duval C., Keshtkar S., Groener J.E., van Rooijen N., Staels B., Kersten S., Muller M. Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity. Hepatology 2010, 51:511-522.
    • (2010) Hepatology , vol.51 , pp. 511-522
    • Stienstra, R.1    Saudale, F.2    Duval, C.3    Keshtkar, S.4    Groener, J.E.5    van Rooijen, N.6    Staels, B.7    Kersten, S.8    Muller, M.9
  • 210
    • 33845497181 scopus 로고    scopus 로고
    • Inflammatory caspases and inflammasomes: master switches of inflammation
    • Martinon F., Tschopp J. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ. 2007, 14:10-22.
    • (2007) Cell Death Differ. , vol.14 , pp. 10-22
    • Martinon, F.1    Tschopp, J.2
  • 211
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K., Tschopp J. The inflammasomes. Cell 2010, 140:821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 212
    • 67049158193 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
    • Cayrol C., Girard J.P. The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:9021-9026.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 9021-9026
    • Cayrol, C.1    Girard, J.P.2
  • 214
    • 34247574122 scopus 로고    scopus 로고
    • Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response
    • Kummer J.A., Broekhuizen R., Everett H., Agostini L., Kuijk L., Martinon F., van Bruggen R., Tschopp J. Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J. Histochem. Cytochem. 2007, 55:443-452.
    • (2007) J. Histochem. Cytochem. , vol.55 , pp. 443-452
    • Kummer, J.A.1    Broekhuizen, R.2    Everett, H.3    Agostini, L.4    Kuijk, L.5    Martinon, F.6    van Bruggen, R.7    Tschopp, J.8
  • 215
    • 79957438570 scopus 로고    scopus 로고
    • Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice
    • Csak T., Dolganiuc A., Kodys K., Nath B., Petrasek J., Bala S., Lippai D., Szabo G. Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice. Hepatology 2011, 53:1917-1931.
    • (2011) Hepatology , vol.53 , pp. 1917-1931
    • Csak, T.1    Dolganiuc, A.2    Kodys, K.3    Nath, B.4    Petrasek, J.5    Bala, S.6    Lippai, D.7    Szabo, G.8
  • 216
    • 77649132053 scopus 로고    scopus 로고
    • Mechanisms and clinical implications of hepatocyte lipoapoptosis
    • Cazanave S.C., Gores G.J. Mechanisms and clinical implications of hepatocyte lipoapoptosis. Clin. Lipidol. 2010, 5:71-85.
    • (2010) Clin. Lipidol. , vol.5 , pp. 71-85
    • Cazanave, S.C.1    Gores, G.J.2
  • 220
    • 77956810224 scopus 로고    scopus 로고
    • Toll-like receptor signaling and liver fibrosis
    • 192543 (Epub 2010 Jul 25)
    • Aoyama T., Paik Y.H., Seki E. Toll-like receptor signaling and liver fibrosis. Gastroenterol. Res. Pract. 2010, 2010. 192543 (Epub 2010 Jul 25).
    • (2010) Gastroenterol. Res. Pract. , vol.2010
    • Aoyama, T.1    Paik, Y.H.2    Seki, E.3
  • 222
    • 0029057032 scopus 로고
    • Experimental biliary fibrosis correlates with increased numbers of fat-storing and Kupffer cells, and portal endotoxemia
    • Grinko I., Geerts A., Wisse E. Experimental biliary fibrosis correlates with increased numbers of fat-storing and Kupffer cells, and portal endotoxemia. J. Hepatol. 1995, 23:449-458.
    • (1995) J. Hepatol. , vol.23 , pp. 449-458
    • Grinko, I.1    Geerts, A.2    Wisse, E.3
  • 223
    • 0028934072 scopus 로고
    • Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation
    • Lin R.S., Lee F.Y., Lee S.D., Tsai Y.T., Lin H.C., Lu R.H., Hsu W.C., Huang C.C., Wang S.S., Lo K.J. Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation. J. Hepatol. 1995, 22:165-172.
    • (1995) J. Hepatol. , vol.22 , pp. 165-172
    • Lin, R.S.1    Lee, F.Y.2    Lee, S.D.3    Tsai, Y.T.4    Lin, H.C.5    Lu, R.H.6    Hsu, W.C.7    Huang, C.C.8    Wang, S.S.9    Lo, K.J.10
  • 225
    • 0033965330 scopus 로고    scopus 로고
    • Hydrogen peroxide: a link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells
    • Greenwel P., Dominguez-Rosales J.A., Mavi G., Rivas-Estilla A.M., Rojkind M. Hydrogen peroxide: a link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells. Hepatology 2000, 31:109-116.
    • (2000) Hepatology , vol.31 , pp. 109-116
    • Greenwel, P.1    Dominguez-Rosales, J.A.2    Mavi, G.3    Rivas-Estilla, A.M.4    Rojkind, M.5
  • 226
    • 0037155835 scopus 로고    scopus 로고
    • Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells
    • Nieto N., Friedman S.L., Cederbaum A.I. Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells. J. Biol. Chem. 2002, 277:9853-9864.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9853-9864
    • Nieto, N.1    Friedman, S.L.2    Cederbaum, A.I.3
  • 229
    • 0036017171 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of alcoholic hepatitis: introduction and summary of the symposium
    • Purohit V., Russo D. Cellular and molecular mechanisms of alcoholic hepatitis: introduction and summary of the symposium. Alcohol 2002, 27:3-6.
    • (2002) Alcohol , vol.27 , pp. 3-6
    • Purohit, V.1    Russo, D.2
  • 230
    • 0025272893 scopus 로고
    • Stimulation of hepatic lipocyte collagen production by Kupffer cell-derived transforming growth factor beta: implication for a pathogenetic role in alcoholic liver fibrogenesis
    • Matsuoka M., Tsukamoto H. Stimulation of hepatic lipocyte collagen production by Kupffer cell-derived transforming growth factor beta: implication for a pathogenetic role in alcoholic liver fibrogenesis. Hepatology 1990, 11:599-605.
    • (1990) Hepatology , vol.11 , pp. 599-605
    • Matsuoka, M.1    Tsukamoto, H.2
  • 231
    • 40749087701 scopus 로고    scopus 로고
    • Innate immunity and alcoholic liver fibrosis
    • Jeong W.I., Gao B. Innate immunity and alcoholic liver fibrosis. J. Gastroenterol. Hepatol. 2008, 23(Suppl. 1):S112-S118.
    • (2008) J. Gastroenterol. Hepatol. , vol.23 , Issue.SUPPL. 1
    • Jeong, W.I.1    Gao, B.2
  • 233
    • 0038185316 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
    • Paik Y.H., Schwabe R.F., Bataller R., Russo M.P., Jobin C., Brenner D.A. Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology 2003, 37:1043-1055.
    • (2003) Hepatology , vol.37 , pp. 1043-1055
    • Paik, Y.H.1    Schwabe, R.F.2    Bataller, R.3    Russo, M.P.4    Jobin, C.5    Brenner, D.A.6
  • 234
    • 41349116553 scopus 로고    scopus 로고
    • A molecular link between inflammation and fibrogenesis: the bacterial microflora influences hepatic fibrosis via toll-like receptor 4-dependent modification of transforming growth factor-beta signaling in hepatic stellate cells
    • Luedde T., Trautwein C. A molecular link between inflammation and fibrogenesis: the bacterial microflora influences hepatic fibrosis via toll-like receptor 4-dependent modification of transforming growth factor-beta signaling in hepatic stellate cells. Hepatology 2008, 47:1089-1091.
    • (2008) Hepatology , vol.47 , pp. 1089-1091
    • Luedde, T.1    Trautwein, C.2
  • 236
    • 63649108380 scopus 로고    scopus 로고
    • The roles of TLRs, RLRs and NLRs in pathogen recognition
    • Kawai T., Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int. Immunol. 2009, 21:317-337.
    • (2009) Int. Immunol. , vol.21 , pp. 317-337
    • Kawai, T.1    Akira, S.2
  • 242
    • 33847042376 scopus 로고    scopus 로고
    • Chronic ethanol consumption impairs cellular immune responses against HCV NS5 protein due to dendritic cell dysfunction
    • Aloman C., Gehring S., Wintermeyer P., Kuzushita N., Wands J.R. Chronic ethanol consumption impairs cellular immune responses against HCV NS5 protein due to dendritic cell dysfunction. Gastroenterology 2007, 132:698-708.
    • (2007) Gastroenterology , vol.132 , pp. 698-708
    • Aloman, C.1    Gehring, S.2    Wintermeyer, P.3    Kuzushita, N.4    Wands, J.R.5
  • 244
    • 0036777957 scopus 로고    scopus 로고
    • The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides
    • Goldberg A.L., Cascio P., Saric T., Rock K.L. The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides. Mol. Immunol. 2002, 39:147-164.
    • (2002) Mol. Immunol. , vol.39 , pp. 147-164
    • Goldberg, A.L.1    Cascio, P.2    Saric, T.3    Rock, K.L.4
  • 245
    • 4544304395 scopus 로고    scopus 로고
    • Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo
    • Osna N.A., Haorah J., Krutik V.M., Donohue T.M. Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo. Hepatology 2004, 40:574-582.
    • (2004) Hepatology , vol.40 , pp. 574-582
    • Osna, N.A.1    Haorah, J.2    Krutik, V.M.3    Donohue, T.M.4
  • 246
    • 27844604269 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production
    • Korenaga M., Wang T., Li Y., Showalter L.A., Chan T., Sun J., Weinman S.A. Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production. J. Biol. Chem. 2005, 280:37481-37488.
    • (2005) J. Biol. Chem. , vol.280 , pp. 37481-37488
    • Korenaga, M.1    Wang, T.2    Li, Y.3    Showalter, L.A.4    Chan, T.5    Sun, J.6    Weinman, S.A.7
  • 247
    • 11144342818 scopus 로고    scopus 로고
    • Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells
    • Otani K., Korenaga M., Beard M.R., Li K., Qian T., Showalter L.A., Singh A.K., Wang T., Weinman S.A. Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells. Gastroenterology 2005, 128:96-107.
    • (2005) Gastroenterology , vol.128 , pp. 96-107
    • Otani, K.1    Korenaga, M.2    Beard, M.R.3    Li, K.4    Qian, T.5    Showalter, L.A.6    Singh, A.K.7    Wang, T.8    Weinman, S.A.9
  • 248
    • 0036829556 scopus 로고    scopus 로고
    • Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus
    • Hassan M.M., Hwang L.Y., Hatten C.J., Swaim M., Li D., Abbruzzese J.L., Beasley P., Patt Y.Z. Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus. Hepatology 2002, 36:1206-1213.
    • (2002) Hepatology , vol.36 , pp. 1206-1213
    • Hassan, M.M.1    Hwang, L.Y.2    Hatten, C.J.3    Swaim, M.4    Li, D.5    Abbruzzese, J.L.6    Beasley, P.7    Patt, Y.Z.8
  • 249
  • 250
    • 4143065907 scopus 로고    scopus 로고
    • Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the US
    • Yuan J.M., Govindarajan S., Arakawa K., Yu M.C. Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the US. Cancer 2004, 101:1009-1017.
    • (2004) Cancer , vol.101 , pp. 1009-1017
    • Yuan, J.M.1    Govindarajan, S.2    Arakawa, K.3    Yu, M.C.4
  • 252
    • 18244365866 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis
    • Perlemuter G., Sabile A., Letteron P., Vona G., Topilco A., Chretien Y., Koike K., Pessayre D., Chapman J., Barba G., et al. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J. 2002, 16:185-194.
    • (2002) FASEB J. , vol.16 , pp. 185-194
    • Perlemuter, G.1    Sabile, A.2    Letteron, P.3    Vona, G.4    Topilco, A.5    Chretien, Y.6    Koike, K.7    Pessayre, D.8    Chapman, J.9    Barba, G.10
  • 256
    • 77956798665 scopus 로고    scopus 로고
    • TLR4-dependent Nanog+ cancer stem cells exhibit defective TGF-beta signaling
    • Machida K., Liu J., Jeong H., Mishra L., Tsukamoto H. TLR4-dependent Nanog+ cancer stem cells exhibit defective TGF-beta signaling. Hepatology 2009, 50(Suppl.):A871.
    • (2009) Hepatology , vol.50 , Issue.SUPPL.
    • Machida, K.1    Liu, J.2    Jeong, H.3    Mishra, L.4    Tsukamoto, H.5
  • 258
    • 66749106254 scopus 로고    scopus 로고
    • Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD)
    • Bellentani S., Marino M. Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD). Ann. Hepatol. 2009, 8(Suppl 1):S4-S8.
    • (2009) Ann. Hepatol. , vol.8 , Issue.SUPPL. 1
    • Bellentani, S.1    Marino, M.2
  • 259
    • 59349102306 scopus 로고    scopus 로고
    • Metabolic syndrome, non-alcoholic fatty liver disease and hepatitis C virus: impact on disease progression and treatment response
    • Younossi Z.M., McCullough A.J. Metabolic syndrome, non-alcoholic fatty liver disease and hepatitis C virus: impact on disease progression and treatment response. Liver Int. 2009, 29(Suppl. 2):3-12.
    • (2009) Liver Int. , vol.29 , Issue.SUPPL. 2 , pp. 3-12
    • Younossi, Z.M.1    McCullough, A.J.2
  • 260
    • 0345655291 scopus 로고    scopus 로고
    • Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected]
    • Hui J.M., Sud A., Farrell G.C., Bandara P., Byth K., Kench J.G., McCaughan G.W., George J. Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected]. Gastroenterology 2003, 125:1695-1704.
    • (2003) Gastroenterology , vol.125 , pp. 1695-1704
    • Hui, J.M.1    Sud, A.2    Farrell, G.C.3    Bandara, P.4    Byth, K.5    Kench, J.G.6    McCaughan, G.W.7    George, J.8
  • 261
    • 64049090624 scopus 로고    scopus 로고
    • MAVS self-association mediates antiviral innate immune signaling
    • Tang E.D., Wang C.Y. MAVS self-association mediates antiviral innate immune signaling. J. Virol. 2009, 83:3420-3428.
    • (2009) J. Virol. , vol.83 , pp. 3420-3428
    • Tang, E.D.1    Wang, C.Y.2
  • 262
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
    • Seth R.B., Sun L., Ea C.K., Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005, 122:669-682.
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 264
    • 70450205079 scopus 로고    scopus 로고
    • Apoptosis and human diseases: mitochondrion damage and lethal role of released cytochrome C as proapoptotic protein
    • Caroppi P., Sinibaldi F., Fiorucci L., Santucci R. Apoptosis and human diseases: mitochondrion damage and lethal role of released cytochrome C as proapoptotic protein. Curr. Med. Chem. 2009, 16:4058-4065.
    • (2009) Curr. Med. Chem. , vol.16 , pp. 4058-4065
    • Caroppi, P.1    Sinibaldi, F.2    Fiorucci, L.3    Santucci, R.4
  • 266
    • 43049181923 scopus 로고    scopus 로고
    • Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis
    • Stadlbauer V., Mookerjee R.P., Hodges S., Wright G.A., Davies N.A., Jalan R. Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis. J. Hepatol. 2008, 48:945-951.
    • (2008) J. Hepatol. , vol.48 , pp. 945-951
    • Stadlbauer, V.1    Mookerjee, R.P.2    Hodges, S.3    Wright, G.A.4    Davies, N.A.5    Jalan, R.6
  • 267
    • 36349031101 scopus 로고    scopus 로고
    • Good science behind hepatitis C virus antiviral drug development: necessary but not sufficient
    • Pappas S.C. Good science behind hepatitis C virus antiviral drug development: necessary but not sufficient. Hepatology 2007, 46:1317-1318.
    • (2007) Hepatology , vol.46 , pp. 1317-1318
    • Pappas, S.C.1
  • 273
    • 0038637373 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha is an important mediator of portal and systemic haemodynamic derangements in alcoholic hepatitis
    • Mookerjee R.P., Sen S., Davies N.A., Hodges S.J., Williams R., Jalan R. Tumour necrosis factor alpha is an important mediator of portal and systemic haemodynamic derangements in alcoholic hepatitis. Gut 2003, 52:1182-1187.
    • (2003) Gut , vol.52 , pp. 1182-1187
    • Mookerjee, R.P.1    Sen, S.2    Davies, N.A.3    Hodges, S.J.4    Williams, R.5    Jalan, R.6
  • 276
    • 20644468617 scopus 로고    scopus 로고
    • Effect of Lactobacillus supplementation with and without arginine on liver damage and bacterial translocation in an acute liver injury model in the rat
    • Adawi D., Kasravi F.B., Molin G., Jeppsson B. Effect of Lactobacillus supplementation with and without arginine on liver damage and bacterial translocation in an acute liver injury model in the rat. Hepatology 1997, 25:642-647.
    • (1997) Hepatology , vol.25 , pp. 642-647
    • Adawi, D.1    Kasravi, F.B.2    Molin, G.3    Jeppsson, B.4
  • 277
    • 34548757869 scopus 로고    scopus 로고
    • Probiotic bacteria prevent hepatic damage and maintain colonic barrier function in a mouse model of sepsis
    • Ewaschuk J., Endersby R., Thiel D., Diaz H., Backer J., Ma M., Churchill T., Madsen K. Probiotic bacteria prevent hepatic damage and maintain colonic barrier function in a mouse model of sepsis. Hepatology 2007, 46:841-850.
    • (2007) Hepatology , vol.46 , pp. 841-850
    • Ewaschuk, J.1    Endersby, R.2    Thiel, D.3    Diaz, H.4    Backer, J.5    Ma, M.6    Churchill, T.7    Madsen, K.8
  • 278
    • 2342580955 scopus 로고    scopus 로고
    • Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis
    • Liu Q., Duan Z.P., Ha D.K., Bengmark S., Kurtovic J., Riordan S.M. Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis. Hepatology 2004, 39:1441-1449.
    • (2004) Hepatology , vol.39 , pp. 1441-1449
    • Liu, Q.1    Duan, Z.P.2    Ha, D.K.3    Bengmark, S.4    Kurtovic, J.5    Riordan, S.M.6
  • 279
    • 0036295030 scopus 로고    scopus 로고
    • Early enteral supply of fiber and Lactobacilli versus conventional nutrition: a controlled trial in patients with major abdominal surgery
    • Rayes N., Hansen S., Seehofer D., Muller A.R., Serke S., Bengmark S., Neuhaus P. Early enteral supply of fiber and Lactobacilli versus conventional nutrition: a controlled trial in patients with major abdominal surgery. Nutrition 2002, 18:609-615.
    • (2002) Nutrition , vol.18 , pp. 609-615
    • Rayes, N.1    Hansen, S.2    Seehofer, D.3    Muller, A.R.4    Serke, S.5    Bengmark, S.6    Neuhaus, P.7
  • 280
    • 0037099390 scopus 로고    scopus 로고
    • Early enteral supply of lactobacillus and fiber versus selective bowel decontamination: a controlled trial in liver transplant recipients
    • Rayes N., Seehofer D., Hansen S., Boucsein K., Muller A.R., Serke S., Bengmark S., Neuhaus P. Early enteral supply of lactobacillus and fiber versus selective bowel decontamination: a controlled trial in liver transplant recipients. Transplantation 2002, 74:123-127.
    • (2002) Transplantation , vol.74 , pp. 123-127
    • Rayes, N.1    Seehofer, D.2    Hansen, S.3    Boucsein, K.4    Muller, A.R.5    Serke, S.6    Bengmark, S.7    Neuhaus, P.8
  • 281
    • 34547657678 scopus 로고    scopus 로고
    • Endotoxin- and D-galactosamine-induced liver injury improved by the administration of Lactobacillus, Bifidobacterium and blueberry
    • Osman N., Adawi D., Ahrne S., Jeppsson B., Molin G. Endotoxin- and D-galactosamine-induced liver injury improved by the administration of Lactobacillus, Bifidobacterium and blueberry. Dig. Liver Dis. 2007, 39:849-856.
    • (2007) Dig. Liver Dis. , vol.39 , pp. 849-856
    • Osman, N.1    Adawi, D.2    Ahrne, S.3    Jeppsson, B.4    Molin, G.5
  • 282
    • 32044431702 scopus 로고    scopus 로고
    • Dysregulated cytokine metabolism, altered hepatic methionine metabolism and proteasome dysfunction in alcoholic liver disease
    • McClain C., Barve S., Joshi-Barve S., Song Z., Deaciuc I., Chen T., Hill D. Dysregulated cytokine metabolism, altered hepatic methionine metabolism and proteasome dysfunction in alcoholic liver disease. Alcohol. Clin. Exp. Res. 2005, 29:180S-188S.
    • (2005) Alcohol. Clin. Exp. Res. , vol.29
    • McClain, C.1    Barve, S.2    Joshi-Barve, S.3    Song, Z.4    Deaciuc, I.5    Chen, T.6    Hill, D.7
  • 285
    • 0031028140 scopus 로고    scopus 로고
    • Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor
    • Yamada Y., Kirillova I., Peschon J.J., Fausto N. Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor. Proc. Natl. Acad. Sci. USA. 1997, 94:1441-1446.
    • (1997) Proc. Natl. Acad. Sci. USA. , vol.94 , pp. 1441-1446
    • Yamada, Y.1    Kirillova, I.2    Peschon, J.J.3    Fausto, N.4
  • 288
    • 52949129811 scopus 로고    scopus 로고
    • Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity
    • Osborn O., Brownell S.E., Sanchez-Alavez M., Salomon D., Gram H., Bartfai T. Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity. Cytokine 2008, 44:141-148.
    • (2008) Cytokine , vol.44 , pp. 141-148
    • Osborn, O.1    Brownell, S.E.2    Sanchez-Alavez, M.3    Salomon, D.4    Gram, H.5    Bartfai, T.6
  • 290
    • 34748903504 scopus 로고    scopus 로고
    • Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a high-fat diet
    • Barbuio R., Milanski M., Bertolo M.B., Saad M.J., Velloso L.A. Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a high-fat diet. J. Endocrinol. 2007, 194:539-550.
    • (2007) J. Endocrinol. , vol.194 , pp. 539-550
    • Barbuio, R.1    Milanski, M.2    Bertolo, M.B.3    Saad, M.J.4    Velloso, L.A.5
  • 292
    • 0028887596 scopus 로고
    • Antitumor necrosis factor antibodies reduce hepatic steatosis during total parenteral nutrition and bowel rest in the rat
    • Pappo I., Bercovier H., Berry E., Gallilly R., Feigin E., Freund H.R. Antitumor necrosis factor antibodies reduce hepatic steatosis during total parenteral nutrition and bowel rest in the rat. JPEN J. Parenter. Enteral. Nutr. 1995, 19:80-82.
    • (1995) JPEN J. Parenter. Enteral. Nutr. , vol.19 , pp. 80-82
    • Pappo, I.1    Bercovier, H.2    Berry, E.3    Gallilly, R.4    Feigin, E.5    Freund, H.R.6
  • 294
    • 29144456824 scopus 로고    scopus 로고
    • Joint effects of body weight and alcohol on elevated serum alanine aminotransferase in the United States population
    • Ruhl C.E., Everhart J.E. Joint effects of body weight and alcohol on elevated serum alanine aminotransferase in the United States population. Clin. Gastroenterol. Hepatol. 2005, 3:1260-1268.
    • (2005) Clin. Gastroenterol. Hepatol. , vol.3 , pp. 1260-1268
    • Ruhl, C.E.1    Everhart, J.E.2
  • 295
    • 18344371820 scopus 로고    scopus 로고
    • Lower risk for alcohol-induced cirrhosis in wine drinkers
    • Becker U., Gronbaek M., Johansen D., Sorensen T.I. Lower risk for alcohol-induced cirrhosis in wine drinkers. Hepatology 2002, 35:868-875.
    • (2002) Hepatology , vol.35 , pp. 868-875
    • Becker, U.1    Gronbaek, M.2    Johansen, D.3    Sorensen, T.I.4
  • 296
    • 34548139334 scopus 로고    scopus 로고
    • Light to moderate alcohol consumption is associated with lower frequency of hypertransaminasemia
    • Suzuki A., Angulo P., St Sauver J., Muto A., Okada T., Lindor K. Light to moderate alcohol consumption is associated with lower frequency of hypertransaminasemia. Am. J. Gastroenterol. 2007, 102:1912-1919.
    • (2007) Am. J. Gastroenterol. , vol.102 , pp. 1912-1919
    • Suzuki, A.1    Angulo, P.2    St Sauver, J.3    Muto, A.4    Okada, T.5    Lindor, K.6
  • 297
    • 46249090385 scopus 로고    scopus 로고
    • Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease
    • Dunn W., Xu R., Schwimmer J.B. Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease. Hepatology 2008, 47:1947-1954.
    • (2008) Hepatology , vol.47 , pp. 1947-1954
    • Dunn, W.1    Xu, R.2    Schwimmer, J.B.3
  • 299
    • 0742301241 scopus 로고    scopus 로고
    • Effect of alcohol consumption on diabetes mellitus: a systematic review
    • Howard A.A., Arnsten J.H., Gourevitch M.N. Effect of alcohol consumption on diabetes mellitus: a systematic review. Ann. Intern. Med. 2004, 140:211-219.
    • (2004) Ann. Intern. Med. , vol.140 , pp. 211-219
    • Howard, A.A.1    Arnsten, J.H.2    Gourevitch, M.N.3
  • 300
    • 23244433350 scopus 로고    scopus 로고
    • Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress
    • Zern T.L., Wood R.J., Greene C., West K.L., Liu Y., Aggarwal D., Shachter N.S., Fernandez M.L. Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress. J. Nutr. 2005, 135:1911-1917.
    • (2005) J. Nutr. , vol.135 , pp. 1911-1917
    • Zern, T.L.1    Wood, R.J.2    Greene, C.3    West, K.L.4    Liu, Y.5    Aggarwal, D.6    Shachter, N.S.7    Fernandez, M.L.8


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