-
1
-
-
0023876502
-
Primary biliary cirrhosis and mitochondrial autoantigens - insights from molecular biology
-
Gershwin ME, Coppel RL, Mackay IR. Primary biliary cirrhosis and mitochondrial autoantigens - insights from molecular biology. HEPATOLOGY 1988;8:147-151.
-
(1988)
HEPATOLOGY
, vol.8
, pp. 147-151
-
-
Gershwin, M.E.1
Coppel, R.L.2
Mackay, I.R.3
-
2
-
-
33745255689
-
New insights to the immunopathology and autoimmune responses in primary biliary cirrhosis
-
He XS, Ansari AA, Ridgway WM, Coppel RL, Gershwin ME. New insights to the immunopathology and autoimmune responses in primary biliary cirrhosis. Cell Immunol 2006;239:1-13.
-
(2006)
Cell Immunol
, vol.239
, pp. 1-13
-
-
He, X.S.1
Ansari, A.A.2
Ridgway, W.M.3
Coppel, R.L.4
Gershwin, M.E.5
-
3
-
-
33645076274
-
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE
-
Ehlers M, Fukuyama H, McGaha TL, Aderem A, Ravetch JV. TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE. J Exp Med 2006;203:553-561.
-
(2006)
J Exp Med
, vol.203
, pp. 553-561
-
-
Ehlers, M.1
Fukuyama, H.2
McGaha, T.L.3
Aderem, A.4
Ravetch, J.V.5
-
4
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 2002;416:603-607.
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
5
-
-
0347480224
-
Activation of autoreactive B cells by CpG dsDNA
-
Viglianti GA, Lau CM, Hanley TM, Miko BA, Shlomchik MJ, Marshak-Rothstein A. Activation of autoreactive B cells by CpG dsDNA. Immunity 2003;19:837-847.
-
(2003)
Immunity
, vol.19
, pp. 837-847
-
-
Viglianti, G.A.1
Lau, C.M.2
Hanley, T.M.3
Miko, B.A.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
6
-
-
14244262923
-
Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis
-
Kikuchi K, Lian ZX, Yang GX, Ansari AA, Ikehara S, Kaplan M, et al. Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis. Gastroenterology 2005;128:304-312.
-
(2005)
Gastroenterology
, vol.128
, pp. 304-312
-
-
Kikuchi, K.1
Lian, Z.X.2
Yang, G.X.3
Ansari, A.A.4
Ikehara, S.5
Kaplan, M.6
-
7
-
-
2142700028
-
K+ channels as targets for specific immunomodulation
-
George Chandy K, WuIff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. K+ channels as targets for specific immunomodulation. Trends Pharmacol Sci 2004;25:280-289.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 280-289
-
-
George Chandy, K.1
WuIff, H.2
Beeton, C.3
Pennington, M.4
Gutman, G.A.5
Cahalan, M.D.6
-
8
-
-
0038481183
-
The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS
-
Wulff H, Calabresi PA, Allie R, Yun S, Pennington M, Beeton C, et al. The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS. J Clin Invest 2003;111:1703-1713.
-
(2003)
J Clin Invest
, vol.111
, pp. 1703-1713
-
-
Wulff, H.1
Calabresi, P.A.2
Allie, R.3
Yun, S.4
Pennington, M.5
Beeton, C.6
-
9
-
-
3142775617
-
K+ channel expression during B cell differentiation: Implications for immunomodulation and autoimmunity
-
WuIff H, Knaus HG, Pennington M, Chandy KG. K+ channel expression during B cell differentiation: implications for immunomodulation and autoimmunity. J Immunol 2004;173:776-786.
-
(2004)
J Immunol
, vol.173
, pp. 776-786
-
-
WuIff, H.1
Knaus, H.G.2
Pennington, M.3
Chandy, K.G.4
-
10
-
-
20144366005
-
Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases
-
Beeton C, Pennington MW, Wulff H, Singh S, Nugent D, Crossley G, et al. Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases. Mol Pharmacol 2005;67:1369-1381.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1369-1381
-
-
Beeton, C.1
Pennington, M.W.2
Wulff, H.3
Singh, S.4
Nugent, D.5
Crossley, G.6
-
11
-
-
0035923519
-
Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis
-
Beeton C, Wulff H, Barbaria J, Clot-Faybesse O, Pennington M, Bernard D, et al. Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis. Proc Natl Acad Sci U S A 2001;98:13942-13947.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13942-13947
-
-
Beeton, C.1
Wulff, H.2
Barbaria, J.3
Clot-Faybesse, O.4
Pennington, M.5
Bernard, D.6
-
12
-
-
20244366860
-
Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice
-
Reich EP, Cui L, Yang L, Pugliese-Sivo C, Golovko A, Petro M, et al. Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice. Eur J Immunol 2005;35:1027-3036.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1027-3036
-
-
Reich, E.P.1
Cui, L.2
Yang, L.3
Pugliese-Sivo, C.4
Golovko, A.5
Petro, M.6
-
13
-
-
2142843025
-
Selective blockade of voltage-gated potassium channels reduces inflammatory bone resorption in experimental periodontal disease
-
Valverde P, Kawai T, Taubman MA. Selective blockade of voltage-gated potassium channels reduces inflammatory bone resorption in experimental periodontal disease. J Bone Miner Res 2004;19:155-164.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 155-164
-
-
Valverde, P.1
Kawai, T.2
Taubman, M.A.3
-
14
-
-
0037487251
-
Primary biliary cirrhosis
-
Talwalkar JA, Lindor KD. Primary biliary cirrhosis. Lancet 2003;362:53-61.
-
(2003)
Lancet
, vol.362
, pp. 53-61
-
-
Talwalkar, J.A.1
Lindor, K.D.2
-
15
-
-
0017895412
-
Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis)
-
Ludwig J, Dickson ER, McDonald GS. Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis). Virchows Arch A Pathol Anat Histol 1978;379:103-112.
-
(1978)
Virchows Arch A Pathol Anat Histol
, vol.379
, pp. 103-112
-
-
Ludwig, J.1
Dickson, E.R.2
McDonald, G.S.3
-
16
-
-
0034711234
-
Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences
-
Ghanshani S, Wulff H, Miller MJ, Rohm H, Neben A, Gutman GA, et al. Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences. J Biol Chem 2000;275:37137-37149.
-
(2000)
J Biol Chem
, vol.275
, pp. 37137-37149
-
-
Ghanshani, S.1
Wulff, H.2
Miller, M.J.3
Rohm, H.4
Neben, A.5
Gutman, G.A.6
-
17
-
-
0031890637
-
Characterization of antimitochondrial antibodies in health adults
-
Mattalia A, Quaranta S, Leung PS, Bauducci M, Van de Water J, Calvo PL, et al. Characterization of antimitochondrial antibodies in health adults. HEPATOLOGY 1998;27:656-661.
-
(1998)
HEPATOLOGY
, vol.27
, pp. 656-661
-
-
Mattalia, A.1
Quaranta, S.2
Leung, P.S.3
Bauducci, M.4
Van de Water, J.5
Calvo, P.L.6
-
18
-
-
0029892610
-
Use of a designer triple expression hybrid clone for three different lipoyl domain for the detection of antimitochondrial autoantibodies
-
Moteki S, Leung PS, Goppel RL, Dickson ER, Kaplan MM, Munoz S, et al. Use of a designer triple expression hybrid clone for three different lipoyl domain for the detection of antimitochondrial autoantibodies. HEPATOLOGY 1996;24:97-103.
-
(1996)
HEPATOLOGY
, vol.24
, pp. 97-103
-
-
Moteki, S.1
Leung, P.S.2
Goppel, R.L.3
Dickson, E.R.4
Kaplan, M.M.5
Munoz, S.6
-
19
-
-
2342541212
-
-
Matsumura S, Van De Water J, Leung P, Odin JA, Yamamoto K, Gores GJ, et al. Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis. HEPATOLOY 2004;39:1415-1422.
-
Matsumura S, Van De Water J, Leung P, Odin JA, Yamamoto K, Gores GJ, et al. Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis. HEPATOLOY 2004;39:1415-1422.
-
-
-
-
20
-
-
0032532294
-
B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice
-
Serreze DV, Fleming SA, Chapman HD, Richard SD, Leiter EH, Tisch RM. B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice. J Immunol 1998;161:3912-3918.
-
(1998)
J Immunol
, vol.161
, pp. 3912-3918
-
-
Serreze, D.V.1
Fleming, S.A.2
Chapman, H.D.3
Richard, S.D.4
Leiter, E.H.5
Tisch, R.M.6
-
21
-
-
0142059887
-
Potassium channels as therapeutic targets for autoimmune disorders
-
Wulff H, Beeton C, Chandy KG. Potassium channels as therapeutic targets for autoimmune disorders. Curr Opin Drug Discov Devel 2003;6:640-647.
-
(2003)
Curr Opin Drug Discov Devel
, vol.6
, pp. 640-647
-
-
Wulff, H.1
Beeton, C.2
Chandy, K.G.3
-
22
-
-
1242337398
-
Primary biliary cirrhosis: An infectious disease caused by Chlamydia pneumoniae?
-
Abdulkarim AS, Petrovic LM, Kim WR, Angulo P, Lloyd RV, Lindor KD. Primary biliary cirrhosis: an infectious disease caused by Chlamydia pneumoniae? J Hepatol 2004;40:380-384.
-
(2004)
J Hepatol
, vol.40
, pp. 380-384
-
-
Abdulkarim, A.S.1
Petrovic, L.M.2
Kim, W.R.3
Angulo, P.4
Lloyd, R.V.5
Lindor, K.D.6
-
23
-
-
0036788465
-
Analysis of TCR antagonism and molecular mimicry of an HLA-A0201-restricted CTL epitope in primary biliary cirrhosis
-
Kita H, Matsumura S, He XS, Ansari AA, Lian ZX, Van de Water J, et al. Analysis of TCR antagonism and molecular mimicry of an HLA-A0201-restricted CTL epitope in primary biliary cirrhosis. HEPATOLOGY 2002;36:918-926.
-
(2002)
HEPATOLOGY
, vol.36
, pp. 918-926
-
-
Kita, H.1
Matsumura, S.2
He, X.S.3
Ansari, A.A.4
Lian, Z.X.5
Van de Water, J.6
-
24
-
-
0142182773
-
Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium
-
Selmi C, Balkwill DL, Invernizzi P, Ansari AA, Coppel RL, Podda M, et al. Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium. HEPATOLOGY 2003;38:1250-1257.
-
(2003)
HEPATOLOGY
, vol.38
, pp. 1250-1257
-
-
Selmi, C.1
Balkwill, D.L.2
Invernizzi, P.3
Ansari, A.A.4
Coppel, R.L.5
Podda, M.6
-
25
-
-
0033755006
-
Fine specificity of T cells reactive to human PDC-E2 163-176 peptide, the immunodominant autoantigen in primary biliary cirrhosis: Implications for molecular mimicry and cross-recognition among mitochondrial autoantigens
-
Shigematsu H, Shimoda S, Nakamura M, Matsushita S, Nishimura Y, Sakamoto N, et al. Fine specificity of T cells reactive to human PDC-E2 163-176 peptide, the immunodominant autoantigen in primary biliary cirrhosis: implications for molecular mimicry and cross-recognition among mitochondrial autoantigens. HEPATOLOGY 2000;32:901-909.
-
(2000)
HEPATOLOGY
, vol.32
, pp. 901-909
-
-
Shigematsu, H.1
Shimoda, S.2
Nakamura, M.3
Matsushita, S.4
Nishimura, Y.5
Sakamoto, N.6
-
26
-
-
0028905099
-
HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: Evidence of molecular mimicry in human autoimmune diseases
-
Shimoda S, Nakamura M, Ishibashi H, Hayashida K, Niho Y. HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases. J Exp Med 1995;181:1835-1845.
-
(1995)
J Exp Med
, vol.181
, pp. 1835-1845
-
-
Shimoda, S.1
Nakamura, M.2
Ishibashi, H.3
Hayashida, K.4
Niho, Y.5
-
27
-
-
0034076796
-
Mimicry peptides of human PDC-E2 163-176 peptide, the immunodominant T-cell epitope of primary biliary cirrhosis
-
Shimoda S, Nakamura M, Shigematsu H, Tanimoto H, Gushima T, Gershwin ME, et al. Mimicry peptides of human PDC-E2 163-176 peptide, the immunodominant T-cell epitope of primary biliary cirrhosis. HEPATOLOGY 2000;31:1212-1216.
-
(2000)
HEPATOLOGY
, vol.31
, pp. 1212-1216
-
-
Shimoda, S.1
Nakamura, M.2
Shigematsu, H.3
Tanimoto, H.4
Gushima, T.5
Gershwin, M.E.6
-
28
-
-
3342921914
-
The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers
-
Mackay F, Tangye SG. The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers. Curr Opin Pharmacol 2004;4:347-354.
-
(2004)
Curr Opin Pharmacol
, vol.4
, pp. 347-354
-
-
Mackay, F.1
Tangye, S.G.2
-
29
-
-
13444287958
-
Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry
-
McClain MT, Heinlen LD, Dennis GJ, Roebuck J, Harley JB, James JA. Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry. Nat Med 2005;11:85-89.
-
(2005)
Nat Med
, vol.11
, pp. 85-89
-
-
McClain, M.T.1
Heinlen, L.D.2
Dennis, G.J.3
Roebuck, J.4
Harley, J.B.5
James, J.A.6
-
30
-
-
4143106857
-
Lack of immunological or molecular evidence for a role of mouse mammary tumor retrovirus in primary biliary cirrhosis
-
Selmi C, Ross SR, Ansari AA, Invernizzi P, Podda M, Coppel RL, et al. Lack of immunological or molecular evidence for a role of mouse mammary tumor retrovirus in primary biliary cirrhosis. Gastroenterology 2004;127:493-501.
-
(2004)
Gastroenterology
, vol.127
, pp. 493-501
-
-
Selmi, C.1
Ross, S.R.2
Ansari, A.A.3
Invernizzi, P.4
Podda, M.5
Coppel, R.L.6
-
31
-
-
9144232256
-
IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA
-
Wagner M, Poeck H, Jahrsdoerfer B, Rothenfusser S, Prell D, Bohle B, et al. IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA. J Immunol 2004;172:954-963.
-
(2004)
J Immunol
, vol.172
, pp. 954-963
-
-
Wagner, M.1
Poeck, H.2
Jahrsdoerfer, B.3
Rothenfusser, S.4
Prell, D.5
Bohle, B.6
-
32
-
-
0037040863
-
Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma
-
Suvas S, Singh V, Sahdev S, Vohra H, Agrewala JN. Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma. J Biol Chem 2002;277:7766-7775.
-
(2002)
J Biol Chem
, vol.277
, pp. 7766-7775
-
-
Suvas, S.1
Singh, V.2
Sahdev, S.3
Vohra, H.4
Agrewala, J.N.5
-
33
-
-
14944361288
-
The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis
-
Corpechot C, Carrat F, Bahr A, Chretien Y, Poupon RE, Poupon R. The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis. Gastroenterology 2005;128:297-303.
-
(2005)
Gastroenterology
, vol.128
, pp. 297-303
-
-
Corpechot, C.1
Carrat, F.2
Bahr, A.3
Chretien, Y.4
Poupon, R.E.5
Poupon, R.6
-
34
-
-
0037033367
-
Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendriric cells
-
Kita H, Lian ZX, Van de Water J, He XS, Matsumura S, Kaplan M, et al. Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendriric cells. J Exp Med 2002;195:113-123.
-
(2002)
J Exp Med
, vol.195
, pp. 113-123
-
-
Kita, H.1
Lian, Z.X.2
Van de Water, J.3
He, X.S.4
Matsumura, S.5
Kaplan, M.6
-
35
-
-
0036246857
-
Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis
-
Kita H, Matsumura S, He XS, Ansari AA, Lian ZX, Van de Water J, et al. Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis. J Clin Invest 2002;109:1231-1240.
-
(2002)
J Clin Invest
, vol.109
, pp. 1231-1240
-
-
Kita, H.1
Matsumura, S.2
He, X.S.3
Ansari, A.A.4
Lian, Z.X.5
Van de Water, J.6
-
36
-
-
0027328383
-
Distribution of B lymphocytes in nonsuppurative cholangitis in primary biliary cirrhosis
-
Nakanuma Y. Distribution of B lymphocytes in nonsuppurative cholangitis in primary biliary cirrhosis. HEPATOLOGY 1993;18:570-575.
-
(1993)
HEPATOLOGY
, vol.18
, pp. 570-575
-
-
Nakanuma, Y.1
-
37
-
-
2542627510
-
Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse
-
Palmer JM, Robe AJ, Burt AD, Kirby JA, Jones DE. Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse. HEPATOLOGY 2004;39:1583-1592.
-
(2004)
HEPATOLOGY
, vol.39
, pp. 1583-1592
-
-
Palmer, J.M.1
Robe, A.J.2
Burt, A.D.3
Kirby, J.A.4
Jones, D.E.5
-
38
-
-
17844381839
-
A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse
-
Robe AJ, Kirby JA, Jones DE, Palmer JM. A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse. HEPATOLOGY 2005;41:1106-1112.
-
(2005)
HEPATOLOGY
, vol.41
, pp. 1106-1112
-
-
Robe, A.J.1
Kirby, J.A.2
Jones, D.E.3
Palmer, J.M.4
-
39
-
-
7844229417
-
Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis
-
Shimoda S, Van de Water J, Ansari A, Nakamura M, Ishibashi H, Coppel RL, et al. Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis. J Clin Invest 1998;102:1831-1840.
-
(1998)
J Clin Invest
, vol.102
, pp. 1831-1840
-
-
Shimoda, S.1
Van de Water, J.2
Ansari, A.3
Nakamura, M.4
Ishibashi, H.5
Coppel, R.L.6
|