Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis

Journal of Biological Chemistry

Volumn 281, Issue 17, 2006, Pages 12093-12101

  Malhi, Harmeet ^a   Bronk, Steven F ^a   Werneburg, Nathan W ^a   Gores, Gregory J ^a  

^a Mayo Clinic College of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL MEMBRANES; DISEASES; LIPIDS; METABOLISM; PROTEINS;

FREE FATTY ACIDS (FFA); HEPATOCYTE LIPOAPOPTOSIS; MITOCHONDRIAL APOPTOTIC PATHWAY; MITOCHONDRIAL DYSFUNCTION;

FATTY ACIDS;

BH3 PROTEIN; BIM PROTEIN; CASPASE; CYTOCHROME C; FATTY ACID; MONOUNSATURATED FATTY ACID; PROTEIN BAX; SATURATED FATTY ACID; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CULTURE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; RAT; STEATOSIS;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CATHEPSIN B; CYTOCHROMES C; FATTY ACIDS, NONESTERIFIED; FATTY LIVER; FLOW CYTOMETRY; HEPATOCYTES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER NEOPLASMS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; RATS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 33744948514     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M510660200     Document Type: Article

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